Lrea019046.1
Basic Information
- Insect
- Leptidea reali
- Gene Symbol
- ZNF296
- Assembly
- GCA_949711725.1
- Location
- CATIXN010000015.1:7434043-7459626[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.56 70 5.3 0.1 1 23 82 104 82 104 0.86 2 13 0.00061 0.076 14.6 4.7 1 23 198 220 198 220 0.99 3 13 1.7e-05 0.0021 19.5 0.7 1 23 226 249 226 249 0.97 4 13 0.084 10 7.9 3.6 1 23 254 277 254 277 0.93 5 13 0.18 22 6.8 4.4 1 23 402 425 402 425 0.95 6 13 0.35 44 5.9 0.2 1 23 432 454 432 454 0.97 7 13 0.00062 0.078 14.6 4.9 1 23 460 482 460 482 0.98 8 13 0.0001 0.013 17.0 2.4 1 23 488 510 488 510 0.98 9 13 0.00061 0.076 14.6 2.1 1 23 519 541 519 541 0.98 10 13 8.9e-05 0.011 17.2 0.6 2 23 586 607 586 607 0.97 11 13 0.018 2.2 10.0 4.8 1 23 624 646 624 646 0.96 12 13 1.8e-06 0.00022 22.6 0.7 1 23 652 674 652 674 0.98 13 13 3.7e-07 4.7e-05 24.7 3.1 1 23 680 703 680 703 0.98
Sequence Information
- Coding Sequence
- atgtTACAGAAAACTATGGAGCCAGCATCTGGTGATCAAATAGAGACTTATATGTACCAAAACTTTAACCAGGAACAATACATGCCGACAACAAGCACATACCAATGTGgtgaacaaaattattttccACTTATCATTCCTCCAAGCAATGAAAAAAGCCGAAAGCCTAGGacaaagaaaacaataaaaaaagaaaagaaaagttttGTTTCAGAGAAAATAACCGATACAGACTTTCCATTCTATGCATGCTCGGTCTGTGATATTACATTTTTACTGCAACGAGAACTTGATTCGCATGTAACTGAACACAAAGATAGAATAACAAGTTATGATTTGAAAATCCGCAATCAGCTCAGGAAAAAAAAGCTCAAGAAggagaagaaaaagaagaagctAAAAGAGGAAGTAACAAATGTGACTATTGAGATAAAACCAGAAGAGGGCTATATTGGTAACGAAAAGGCTTCGGATGTTGCAAATGAAGAAAAGTTTGTGCCGAACGACAAAATgaatgatgtaataaaaaagcagGACTTATTAATGACTGATGAAGCGAAACGAAAGGAGTTATTGAACCTGGAGAAGATATACAAATGTCACGCTTGTAAGAAGCAGTTCTCATTGAGTTATTACTTGAAGTTGCACGTCCGGTCTCATACAGATGAAAAGCCCTACACGTGCGACAAATGCGGTCAATCATTCATAACAGCAAGTAAACTGGGTAGGCACAACAAGCGAATACATCTCGCGATTCACTTCACGTGCAGGATATGCTATAAGAAATATTACAGatTTGAGTTGCTAACCGACCATTTTGACAAGAAACACGCGGAGGATAAGTTGGAGGGAGAGCCCTACGGTGACAAGGTGGAGAGTGAAGTGAAGGAAGAGTTGGAGATCAAGGTAGAGATTGCCCAAGTGCTGATGGATGAAGTAATTGTCAAAGTGGAACCAGTGGATGATGAATTTAATGCCTGCGATCGGAATTTGGATGGAGctaatgatgatggtgatgacgGACCTCACATAGATGCTGATGACTGCTCCAACAACGGTGATGGTATTCCGGAAGATAACAAGGACGACATAAAGGAAGACGTCAAAGAAGATGATGTCAAGGATGATGAGAAGAAGgtgaagaagaaaaagaaagcgCTGAAAAAGCAAAAGGAGATTGAGAAGAAACGCAAGAAGAGACCGCACGCGTGCGACTACTGCCAGAAGAGATTCTTGCACATGGAGACACTGTTGTCGCACAAGAGGTCCCTGCATGCCGGTGAGACCATAAAGCACGTGTGCAAGTTCTGCCTGGAAGAGTCTGAGGATGCAGCAGCCCTGAAGGAACACGAGAGCACGCACGTGGGGGCCACGCCCTACGTGTGCACGCTATGCGGGAAGTGCTACAAGAAACGGGAGTCTATGATGTACCACAGGAAGAGTCACAAAACTGAGTCCAACTACATCTGCGACATCTGCACCAAGTCCTTCAACGCCCAGTGTAAGCTCCAGCGACACCTGCTGAGCCACACCACGGAGAAGTTCATCCTCAAGTACGAATGCCCGGTCTGTGCACACATGTTCAACACCAAGTACCACATACAGATGCATTTGGCTACCCACCAGCGGGAGGGGATAATTCACGAAGAAAACCGCAACCAGATTCTTGCCATGGTGCTACAGAACGCTCGCAAGATACCAAAGGAAGGCGATTCCTCGCTTCTCACAGTCATACCCACTGACGAACGAAGCCGCGTGTGCAACATATGCGGTGAGGTATTCCAACACTTCTACTATCTAGAGGAGCACCTCAAAAGCCACGGCTCAAAAATCGCCATCGAAAACGTCGAGACAGAGGAGGAAAAAAAGCATGTATGCGAAGTGTGCAATAAAGGCTTCAAACTGCATTACTATTTGAAACTGCACagtttcacgcacactaaagagAAGCCGTTTATATGCCAGCAGTGTGGTAAGGGTTTTATCACTCGGGGCAAACTGAAGAGGCATTTGGAGACGCATTCGGGCCTTAAAAAGTACCAATGTCACATTTGCTATAAGTTCTTCACGAGACCAAGCTATTTACGGATACATGTGAGGACTATTCATGGGACACAAGTTATCATGAACGACAAATTTGGTTTGGAAGCAGGGCTTAATATGTGA
- Protein Sequence
- MLQKTMEPASGDQIETYMYQNFNQEQYMPTTSTYQCGEQNYFPLIIPPSNEKSRKPRTKKTIKKEKKSFVSEKITDTDFPFYACSVCDITFLLQRELDSHVTEHKDRITSYDLKIRNQLRKKKLKKEKKKKKLKEEVTNVTIEIKPEEGYIGNEKASDVANEEKFVPNDKMNDVIKKQDLLMTDEAKRKELLNLEKIYKCHACKKQFSLSYYLKLHVRSHTDEKPYTCDKCGQSFITASKLGRHNKRIHLAIHFTCRICYKKYYRFELLTDHFDKKHAEDKLEGEPYGDKVESEVKEELEIKVEIAQVLMDEVIVKVEPVDDEFNACDRNLDGANDDGDDGPHIDADDCSNNGDGIPEDNKDDIKEDVKEDDVKDDEKKVKKKKKALKKQKEIEKKRKKRPHACDYCQKRFLHMETLLSHKRSLHAGETIKHVCKFCLEESEDAAALKEHESTHVGATPYVCTLCGKCYKKRESMMYHRKSHKTESNYICDICTKSFNAQCKLQRHLLSHTTEKFILKYECPVCAHMFNTKYHIQMHLATHQREGIIHEENRNQILAMVLQNARKIPKEGDSSLLTVIPTDERSRVCNICGEVFQHFYYLEEHLKSHGSKIAIENVETEEEKKHVCEVCNKGFKLHYYLKLHSFTHTKEKPFICQQCGKGFITRGKLKRHLETHSGLKKYQCHICYKFFTRPSYLRIHVRTIHGTQVIMNDKFGLEAGLNM
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -