Lrea013811.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Leptidea reali
Gene Symbol
-
Assembly
GCA_949711725.1
Location
CATIXN010000010.1:22451999-22501091[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 19 0.0028 0.36 12.5 0.6 1 23 325 347 325 347 0.99
2 19 0.0064 0.8 11.4 0.7 1 23 354 377 354 377 0.94
3 19 2.1 2.7e+02 3.4 0.9 1 17 408 424 408 425 0.85
4 19 0.76 95 4.9 0.8 2 23 449 471 448 471 0.95
5 19 0.035 4.4 9.0 0.7 2 20 487 505 486 508 0.89
6 19 4.3e-06 0.00054 21.4 2.1 1 23 514 536 514 536 0.97
7 19 0.0029 0.36 12.5 2.1 1 23 543 565 543 565 0.98
8 19 0.14 18 7.2 8.3 1 19 571 589 571 594 0.93
9 19 2.2 2.8e+02 3.4 3.0 1 23 912 934 912 934 0.94
10 19 0.00084 0.11 14.1 1.1 1 23 941 964 941 964 0.97
11 19 0.32 41 6.0 0.2 2 23 969 990 968 990 0.96
12 19 0.14 17 7.2 1.1 1 23 995 1018 995 1018 0.95
13 19 0.0043 0.54 11.9 0.7 1 23 1022 1045 1022 1045 0.96
14 19 0.55 69 5.3 0.3 2 21 1058 1077 1058 1082 0.91
15 19 0.078 9.8 8.0 0.5 2 23 1124 1146 1123 1146 0.95
16 19 0.00011 0.014 16.9 0.2 2 23 1162 1183 1161 1183 0.96
17 19 1.7e-08 2.1e-06 28.9 1.1 1 23 1189 1211 1189 1211 0.99
18 19 0.0002 0.025 16.1 3.5 1 23 1218 1240 1218 1240 0.98
19 19 8.9e-05 0.011 17.2 0.6 1 23 1246 1269 1246 1269 0.95

Sequence Information

Coding Sequence
ATGCCTAGATGTAGTATTGTACAATGTGTAAATGCAAAAGGCACAAACAAAAGCAGACACTCGTTTCACAGGTTTCCAAGTAATCCAGAATTAAAGAAGAAATGGTTGGAAGTAGTAGGTGAAAAGAATCTGAACCCGTTACACCAAGATTGGTTTATATGTGCGTCCCACTTTAAGGAAAGTGACTTCAATAAGACACTGGAAGTGGTGAGACTCCATGATGATACAATACCTTCTCTCTCTCTGGTTTGCAGGCTGTGTTTAGTTACTGGTGTTAAAATGTACGACATGATAGAAAAAGACTTACATGAGATATACCTAGAAATAACAGGCGTGCCAGCGTACGCAGATGACCCGCTACCCCAGTTAGCATGTGTGGAATGTATCCACAGACTAAATAATTGCAATCTGTTTAGAAACAAGTGTCGCAGAGCTCACAGGGTGCTCCAGGAAATTATTGACAACTCTGACAATGTAAGTAtggataaaatcaaaaatatagatcGTGATTCAGCCCTATTGACAAGTAATCTTACAAAAGTTGTGAATATAAATAGCTATGATTGCAGTTTGGTTTACAATGACGCTAATGAAACTATAAAACAGTTAAAATTTGAAGAACATTACAGCAGTGATGTTGAATATAACAGTGTTGATACAattgaaaataacattaatgacGATGACGGGGCAATTAATAATGAACACCCGCTATTTTTGGAAATTGACACTGATAATACAAGCAGACATACAACATCAAAAGATTCGAACGTAGAACAGAACGGTGTCAACGTGAGTCAGAAGTGGGATGACATACGGATATTGTGGAGAGGTAGAAAGAGAAGGCCTAGGGCACGGACTGGTTTTAAAGATTCACTCGAAGATAAGTTTGTGATAACCGACTTGACGTACGAAGAACAACTTGCGGAAGTGCACAAGAGACGGGAATCTGCGAATTATAAGAATAGCACTTACAGGTGTTCGCTGTGTTTCAAAGGGTTTTTGGATGAGGACGCCTTTAAAGCGCATATGATGAGGCATACTCGAGAATGCGGGGAATATGAATGCGGGATTTGTAAAGTGCACTATAAGACCTTAGCGAAGCTCTACAAACACATATCGGGTGTACACTTGATGAGATACAGCTGCAAACGTTGCCCGTTTACAACGTTGCATATAGCATTAGCTCGAAGTCACGATAGATGGCATGATGGGAAGAAGTTCCATTGTCAACACTGCTCTCAAGAATTTAAAGTAGCCAATGAGTACAGGAAGCCATCACTGAGAAAGAAGGGGATAAGGTTGGCGGGCTTCCGACGAGAGCGTGTTCTTGAAGAACCTTTGTCGTGTGAACAGTGTGACGTACAGTTAAACAGCGTGCACGAATATAACGCGCACTTCAGAAGGGAACACCCCGACAAGAATCGAACCGTGTACCCCACAATTAAGGCGCCGTGTATGTGTGAAATCTGCGGGAGGATTTTTCAGAGCCGCGCTGTACTGAGAGATCACCGGTGGACTCATACCGGCGAGACACCGTTCAGGTGTACGGACTGTGGCAAGACCTTCAGCTCAAGAAAACAGTTGGTCGTTCACGAACATGTGCACACTGACGAACGAAAAACTTTCCAGTGCGGGTTGTGCGCCAGAGAGTTTTCTACGCGGGGAAATTGTCGTCGGCATATGAGTGTTCACACAACTATTCGACCGCACCAATGCGAATTGTGCGGCAAATGTTTCAAAACGCCACACGAAAAGAAATCTCACTGTGATTACGTGCATCTTAAGAAGCCGTGGCCTCGGAAGAGCCGGGGGAAACTGAATGTTAAAGACACTGTGAAGGGCTTTGATCCTAATTTTGTATGGGATACTTGTAAATCAGCCATTCCATGGATTCCACCACTTATTTGGAATAATTTATTGCAAGCTAAGATGACAGACGTGGAAGTTGAAGAACTGCAGgtTTGCAGATTATGTCTAGACACCGGAGTTAAAATGCATAATATGGCTGAAAGAGATTTAAATGAGATATATATGTACATCACGGGCCTACCGACTAATACAGGCTTACCACAGACGGTGTGCTGGGAGTGTTCACACAGACTCATAGCTGCGAATGAGCTAAGAAGCAAGGCGATACAATCCCATAACATACTGCTCGGATTACTTCATTCCAAAACATCTGTGACTATAAGTGATATTGAATCAATAGACCGCAGAAAACTTAACCTTAAATCTAATTTAACCTCTGTGAACATATTAATAGAATATCCCCCATCAattgatgaaattaaaaatgaaatcaaaaatgaTAATGACGTAAATGATAATCAATTTAATGAAGATGTTAATAGTGGAGTTAAAGAACCAAAGAATGAAGATAGTAATGAGATATTCTTTGAAGAGTGTGACTATCTTAGTGAAGATGATAGGACTTTGAGTGAAATGTGTAAAGTAGATAGTGGGATATATAAAGTAGATAAAGTGAAATGTAAAGTGAGTAGAGTGAAGCGTAAAGTTAAAGTGAAGAAAGAACTGAAAAAACGACAGAAAGTGGAGAAGGGTATGGAAGATGAAACAACGGATGAAAGATGTAAATCATTGTTTGTGAAGCGTCGAGCTACAAATGACAGAATAGATGAGGACTTGTTCACAATCACAACACTGACCTTCGAAGAACAAATTGAGGAGATTAATAAGAGACAGGAGTCTACCTTTTATAAGAATGCTATGTTTAAATGTACTGAATGCTTTCGTGGGTTCCATATCAAGGACAGATATGATTCACATATTGTTCGGCATAGTGAGCGAAGTGGGGCGTACCCGTGCTTCATATGCAAGACAAGGTTAAAGACCAATCGTGCCTTGCGAAAACATCTGATGTCACTACACACAGAGCAAATTAGGTGTAAAGGGTGCCCCTTTGTCACTAAAAATAGGGGCGTCGCCCGCGATCATCAGAAATGGCACGCAGGGACAACGTACCAATGTCCTCACTGTCCGAGCCAATTTGACAAAGTGACAACATACCTCGGCCATGTGCGGATAAAGCATGCATCCGACTTTGTCTGTGAACTGTGCGGATTCACGTTTGTGAGTCAAAAAGGGATAGAGCTACACAAGAAGAAGAAACATAGGATGACTGACTTGGAGGTGACTCTGGAGGGTCCCTACTGTGATGTCTGCGATGTGCGTTTCGTGTCCCAAGAAGCCCATCTTCGACACATAAAGCTGTCCGTTCGACACAGCGATGGTAACGAAACGAATCGGATTCGGAACGACTCTCAGGATATCAAAGCACAGCAGAGCATTCTCGGACGGAAGATCGAGAGGCGACATGTGGACAGACAGGCGGACACACAGCTCATTACGTGCGAACAGTGCGGCAAGCAAGTGCGAGGCTTGAGGCAGTACATCCAGCATTTCAAACGCGTGCATCCTGACAAGAATCGAACCAAGTACCCGGCGATGAAGACGCCGTCGATGTGCGAGCTCTGTGGGAAGATATTCCAGACCACGGCCCTGTTGAAAACACATATGCTGGTGCATACGGGCGAGAAGAGTTTCAAATGCGATGAATGCAACAAGAGTTTCTCGCAGAAGACAAACCTTGTGGTGCATATGAGAGTCCACAGTTCCTCGCGACCCAGCTTCGAGTGTCCGCTCTGTGGTAAACACTTCGCTTCCGATCATAATAGGAAAAGGCATATGTATATACACACCGGCCTAAAGCTCTTCAAATGTGACACGTGCGGCAAAGGTTCTACGACCTCGGACGCACTGCGCTCTCATATTGAGCACGTGCATCTCAAGAAGCCGTGGCCTAAGCGAGTGAGGCGAGGTGACGAATGCCCGCTTGAAGATTGA
Protein Sequence
MPRCSIVQCVNAKGTNKSRHSFHRFPSNPELKKKWLEVVGEKNLNPLHQDWFICASHFKESDFNKTLEVVRLHDDTIPSLSLVCRLCLVTGVKMYDMIEKDLHEIYLEITGVPAYADDPLPQLACVECIHRLNNCNLFRNKCRRAHRVLQEIIDNSDNVSMDKIKNIDRDSALLTSNLTKVVNINSYDCSLVYNDANETIKQLKFEEHYSSDVEYNSVDTIENNINDDDGAINNEHPLFLEIDTDNTSRHTTSKDSNVEQNGVNVSQKWDDIRILWRGRKRRPRARTGFKDSLEDKFVITDLTYEEQLAEVHKRRESANYKNSTYRCSLCFKGFLDEDAFKAHMMRHTRECGEYECGICKVHYKTLAKLYKHISGVHLMRYSCKRCPFTTLHIALARSHDRWHDGKKFHCQHCSQEFKVANEYRKPSLRKKGIRLAGFRRERVLEEPLSCEQCDVQLNSVHEYNAHFRREHPDKNRTVYPTIKAPCMCEICGRIFQSRAVLRDHRWTHTGETPFRCTDCGKTFSSRKQLVVHEHVHTDERKTFQCGLCAREFSTRGNCRRHMSVHTTIRPHQCELCGKCFKTPHEKKSHCDYVHLKKPWPRKSRGKLNVKDTVKGFDPNFVWDTCKSAIPWIPPLIWNNLLQAKMTDVEVEELQVCRLCLDTGVKMHNMAERDLNEIYMYITGLPTNTGLPQTVCWECSHRLIAANELRSKAIQSHNILLGLLHSKTSVTISDIESIDRRKLNLKSNLTSVNILIEYPPSIDEIKNEIKNDNDVNDNQFNEDVNSGVKEPKNEDSNEIFFEECDYLSEDDRTLSEMCKVDSGIYKVDKVKCKVSRVKRKVKVKKELKKRQKVEKGMEDETTDERCKSLFVKRRATNDRIDEDLFTITTLTFEEQIEEINKRQESTFYKNAMFKCTECFRGFHIKDRYDSHIVRHSERSGAYPCFICKTRLKTNRALRKHLMSLHTEQIRCKGCPFVTKNRGVARDHQKWHAGTTYQCPHCPSQFDKVTTYLGHVRIKHASDFVCELCGFTFVSQKGIELHKKKKHRMTDLEVTLEGPYCDVCDVRFVSQEAHLRHIKLSVRHSDGNETNRIRNDSQDIKAQQSILGRKIERRHVDRQADTQLITCEQCGKQVRGLRQYIQHFKRVHPDKNRTKYPAMKTPSMCELCGKIFQTTALLKTHMLVHTGEKSFKCDECNKSFSQKTNLVVHMRVHSSSRPSFECPLCGKHFASDHNRKRHMYIHTGLKLFKCDTCGKGSTTSDALRSHIEHVHLKKPWPKRVRRGDECPLED

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00875381;
90% Identity
iTF_00875381;
80% Identity
iTF_00875381;