Lrea018761.1
Basic Information
- Insect
- Leptidea reali
- Gene Symbol
- -
- Assembly
- GCA_949711725.1
- Location
- CATIXN010000015.1:3898601-3904871[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 19 9.9 1.2e+03 1.3 0.2 1 22 56 77 56 79 0.76 2 19 2.8 3.5e+02 3.1 1.0 2 23 110 132 109 132 0.92 3 19 0.0057 0.71 11.5 1.0 2 23 155 177 154 177 0.96 4 19 0.0021 0.26 12.9 1.2 1 23 182 205 182 205 0.95 5 19 0.0031 0.39 12.4 1.9 1 23 210 233 210 233 0.96 6 19 0.0085 1.1 11.0 0.3 3 23 240 261 238 261 0.91 7 19 6.8e-05 0.0085 17.6 0.9 2 23 269 291 268 291 0.97 8 19 0.013 1.7 10.4 0.2 2 23 298 319 297 319 0.96 9 19 2.2e-05 0.0027 19.2 0.1 1 23 325 347 325 347 0.97 10 19 0.0084 1.1 11.0 2.2 1 23 353 376 353 376 0.97 11 19 0.012 1.6 10.5 0.6 1 23 446 468 446 468 0.98 12 19 0.13 16 7.3 0.0 2 23 494 516 493 516 0.90 13 19 0.17 21 6.9 0.6 2 23 539 561 538 561 0.94 14 19 2.2e-05 0.0027 19.1 0.9 3 23 569 590 568 590 0.98 15 19 0.0031 0.39 12.4 1.1 3 23 597 618 596 618 0.97 16 19 0.012 1.6 10.5 2.1 1 23 624 647 624 647 0.97 17 19 5.6e-05 0.007 17.9 1.7 2 23 654 676 653 676 0.95 18 19 0.0051 0.64 11.7 0.8 1 23 682 704 682 704 0.95 19 19 0.0053 0.66 11.6 1.0 1 23 710 733 710 733 0.90
Sequence Information
- Coding Sequence
- ATggatgaaaactgtcacagcacaaatcaaataaatctagGACCCTTAGTTCCTCAAGAGGGCAAGCAAAAAGAACTATCAGAAAAGTTGACTATCAAACGTCGCAACATTGAAAATATCTTACTTTATAGCAACGCAACTCCCTTCCTGTTCTACAAGGGACACTATAGGTGCTTTTACTGCAGACAAATTATGAAAGACCCGGTAATATTACGTGAACATACAGCTAATGTCCATCAATATGTAAATCTTGAAGCTATTGTCTACGATAGAACGAAGACGTATCATAATAAAGACGCAGCTACCAAAATTGATGTCACAGATCTGAAGTGTCGTCTCTGCTTTAAGTCTTTACTGGATTTGGATCAGTTTATTCATCACCTTACAATCGCTCATGATATGGAATACGATATGACTGTTTCAAACTGTCTTTTGTCATTTAAGCTGGATAAATATCAATCAACGTGCTCAATCTGTAACATGAAATTTGTCTTCTTCGAGTACCTTCTTCGCCATGCAAATAAATACCATCTGTCTCACGACTATATTTGCGACGTCTGCGGTACGAGTTTTCAGGGGGAGAATCATCTGCAAATGCACAACAGATATTATCATAAAGAGGGTGGCTATAAGTGCGATCATTGTGGCATAAACTTTGCAACCCTTTCGAAGAAGTTCTTACACGAAAGAAACGTGCATTTAGCCCATCAGATGGCTTGCCCGTATTGCACAGAGACGTTTAAAAGTCCGTACTTTAAGAAGTTACATTTGGCGAATGTACACGGTGTTGCAGAGTTGAAAATTAAGTGCCGCTTTTGCGCAAAAGTTTTTCCCCAGCAAAGTTTGATGTCGAAGCATATGCGGCGAGTACATTTGAAAGAGAAAAACGTGGAATGTCCCATCTGTGGGGACAAGTTTTTCGAAGCCCATGACGTGAAACTTCACATGTTGAAACATAGCGGAGATAAAAAATTCGTATGTTCGGTCTGCGGCAAGCAATTTGCCAAAATAGGAAATCTGAATCAACATTTGACCATACACAATGGCAAGAAACCTTTTGAATGCAGTATTTGTTTGAACGAATTCGCTCATCGCTCTAATTTGAATTTCCATATGAAATCGAATCATCCGGAGCATTTGAGTGAAAAAAATACATGGACTAGGGCTGGTCAGGACTCAAGAAATGCTATAACTGAAGCCTTTAATGGTTTTCCTGCAACGAGTCAACGGAAATCTGACTTGACGGTTAAAGAAAAACGGTGCGCTATGCGTAATAATGTAATACAAGTCCTCATAAAGTCCACAGTAATGCCGTTCCGATGGCTCAAAAGTTCCTACCgctgtttttattgctacgatATCTTTCAAGAGCCATCCGAGTTGAAAGATCATCAGCAAATACATTCAGGAGATGATGTGAAAGTGAATGCCATGAATAAGTATTGGGAACCAGTTGTCTATATTGATATATCGAATCTCACTTGCAAATTATGTCCGGAGAATATCAGTGATCTGTACGACTTAATTGACCATTTAGTTGAGAAACATGGTGTTGCTTACAATAAAGATATTGGATTATGCATGATACCATTCAAGTTAGACAATTTATCATTGAATTGTTTGACTTGTGGCgcaattttttatacatttggaCCTTTGCTGCACCATACAAATAAGGACCACAAAGGAGTCTCAGCGATTCTCTGCGATGTCTGCGGACAACATTTCAAAGACGCCAACCTACTGAAACTGCACATGAAAACTGTGCACGAAAATAACGGGTTGCTGTGCCAAGATTGTGGGGATAAATTTGAGTCGAGGTACAAGTTGAAAAGTCATCAGAAATATGAGCATAACGTGGACAAGAAATATAAATGTATGGAATGTCCGCAGATGTTTCAGAGTCATTACAAACGATCGAGGCATATGGCTGTTGAGCACAAGACAAGAGAGGAAGTGAAATGCCCGCATTGCcctaaaacttttgtttttcgGAGTATGATGATGACTCACCTAAGAGATACGCACCTCAAAGTAAGGAATTACATTTGCAGCGTCTGTGGTTGGAAGGCTTTTAATAGTAATAGGTTGAAGAATCATATGTTTAAGCATAGCGGGGAGAAGAACTTTAAGTGCGATGTGTGCGAGAAAATGTTTAGTACTCGTAAGATTATGCGCGCGCATTTTATAAGAATGCACaaaagtattcaaagtcaaccAGTTCCGTATGATCCTTATGGCGATTGA
- Protein Sequence
- MDENCHSTNQINLGPLVPQEGKQKELSEKLTIKRRNIENILLYSNATPFLFYKGHYRCFYCRQIMKDPVILREHTANVHQYVNLEAIVYDRTKTYHNKDAATKIDVTDLKCRLCFKSLLDLDQFIHHLTIAHDMEYDMTVSNCLLSFKLDKYQSTCSICNMKFVFFEYLLRHANKYHLSHDYICDVCGTSFQGENHLQMHNRYYHKEGGYKCDHCGINFATLSKKFLHERNVHLAHQMACPYCTETFKSPYFKKLHLANVHGVAELKIKCRFCAKVFPQQSLMSKHMRRVHLKEKNVECPICGDKFFEAHDVKLHMLKHSGDKKFVCSVCGKQFAKIGNLNQHLTIHNGKKPFECSICLNEFAHRSNLNFHMKSNHPEHLSEKNTWTRAGQDSRNAITEAFNGFPATSQRKSDLTVKEKRCAMRNNVIQVLIKSTVMPFRWLKSSYRCFYCYDIFQEPSELKDHQQIHSGDDVKVNAMNKYWEPVVYIDISNLTCKLCPENISDLYDLIDHLVEKHGVAYNKDIGLCMIPFKLDNLSLNCLTCGAIFYTFGPLLHHTNKDHKGVSAILCDVCGQHFKDANLLKLHMKTVHENNGLLCQDCGDKFESRYKLKSHQKYEHNVDKKYKCMECPQMFQSHYKRSRHMAVEHKTREEVKCPHCPKTFVFRSMMMTHLRDTHLKVRNYICSVCGWKAFNSNRLKNHMFKHSGEKNFKCDVCEKMFSTRKIMRAHFIRMHKSIQSQPVPYDPYGD
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -