Basic Information

Insect: Leistus spinibarbis
Gene Symbol: YTHDC2
Assembly: GCA_933228875.1
Location: CAKOGB010000082.1:148832-164037[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.00011 0.0096 16.7 0.7 1 23 1731 1753 1731 1753 0.98

2 10 4e-05 0.0033 18.2 3.0 1 23 1759 1781 1759 1781 0.98

3 10 9.7e-06 0.00081 20.1 0.2 1 23 1825 1847 1825 1847 0.98

4 10 0.093 7.8 7.6 0.7 3 23 1854 1876 1854 1876 0.95

5 10 0.00024 0.02 15.7 0.1 1 23 1882 1904 1882 1904 0.95

6 10 0.0018 0.15 13.0 0.8 1 23 1910 1932 1910 1933 0.95

7 10 0.00045 0.037 14.9 1.0 1 23 1938 1960 1938 1960 0.97

8 10 0.004 0.34 11.9 1.6 1 23 1966 1988 1966 1988 0.97

9 10 0.0016 0.14 13.1 9.9 1 23 1994 2016 1994 2016 0.98

10 10 5.9e-05 0.005 17.6 0.1 1 23 2022 2047 2022 2047 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.00011	0.0096	16.7	0.7	1	23	1731	1753	1731	1753	0.98
2	10	4e-05	0.0033	18.2	3.0	1	23	1759	1781	1759	1781	0.98
3	10	9.7e-06	0.00081	20.1	0.2	1	23	1825	1847	1825	1847	0.98
4	10	0.093	7.8	7.6	0.7	3	23	1854	1876	1854	1876	0.95
5	10	0.00024	0.02	15.7	0.1	1	23	1882	1904	1882	1904	0.95
6	10	0.0018	0.15	13.0	0.8	1	23	1910	1932	1910	1933	0.95
7	10	0.00045	0.037	14.9	1.0	1	23	1938	1960	1938	1960	0.97
8	10	0.004	0.34	11.9	1.6	1	23	1966	1988	1966	1988	0.97
9	10	0.0016	0.14	13.1	9.9	1	23	1994	2016	1994	2016	0.98
10	10	5.9e-05	0.005	17.6	0.1	1	23	2022	2047	2022	2047	0.97

Sequence Information

Coding Sequence: ATGGCTCCTCACAGATATACCATGAATATTATTGTATCGGAAGAATTTCGCGTACAATCCGAAATGATTTTACGCAATTTTCTACACGATGAAAATGTCGCTGCGTACGAATTTCCGACTAATTTAACAAATATCGAAAGAGCATGGTTACACAATTACGCTAAAACATTAGGCCTATCATCAAAATCAATTGGCAAAGAGCCTACTCGAAAAATTACACTGTCCAAACCTAATGCGGAGCGGGGACAACAAAATAGGATACCATTAACGGTTTCTAGGGAAAATATGACGACGATCCGAGATTTCTTCCTTAGATACCCAAAGAATTGTGGGGATGGGAGTAAATTGCGTATTCGCTCCAAAAACAATATAGAGGGTACTGACACTAATATGGGACAGCTAACTGTCGGTATCCCACAACTGCCCGTTTTCTCACTATGCAACGACTTGATTGCGTTCCGCATGGAGCTTCCAATATGGCCGATGCGGGATACCCTAATGGAAGCAATCGTTTCCAATCAAGTTGTTATTGTCTGCGGGGAGACCGGATCTGGGAAAACGACCCAAATCCCACAGTTCATATTGGATTATAGCGCATCAGTAAAGGAAAAGACGCGGATTATATGCACACAACCTCGCCGAATATCTGCGGTTGCCGTTGCTGAGCGAGTTGCAGCCGAACGCGGCGAAAAGTCGGGCCAAACGGTAGGGTTTCACATACGATTAGAGTCGTGCGTTGGCCCCAAAACCGTTTTGGTGTATTGCACCAACGGGATTCTATTGCGGACACTGATGAACGGGGATGCTTGCTTGAATTCGTTCACCCATGTTATAGTGGACGAGATCCACGAGCGAGATAGATTCAGCGACTTTCTATTGATTTGCCTCCGCGAATGTCTGGTCAATTACCCTCATTTGCGATTAATTTTAATGTCAGCGACTATGGATGTGCAATCATTCCAATCTTATTTCAATAATGCACCAGTTATCTTTATACCTGGTCGTCTCCACTCAGTGAATGAGTATTACATGGAGGATATTTTAAAAATAACTAATTATGAATCAGCAACCATGACTAACTTGAAAAAGCAACACGCCAAAATGGTCCATCTGCCTGTAAGGCCACAAACTCCGATTATTCAGAATTACAACATGAATTTAGACTTGCAATTTGAGATGATTGATTGCATTAATGACTGCGTTGAATTCGGTTCGGACGAATCATTTACGCAACTGTTGCAACTCATTTTATCTGATCACGCACCGGTTAATTTCCAACACCCAGAAACTATGGTCACAGGACTTATTGCTGCTGCAATACACGGTAACCTTAACATTTGCACTGAGTTACTTAACTATGGAGCCGATGTTAAATTAGTATCTAAAGAGAAATTAACAGCGTCGGATTGGGCTCGACGCAACCAGCACGTCGATGTGGTCGAACTCTTAAACCACTACGATCTATACATGGAAAATGCATCTACATCAAATCAGTGTTCAATAAGCGACGATGATAAAGAATTATTAGACCTATACCATAACACGATCACTGATCAGTTAATTGATTTTGATTTATTGATAGTCTTACTATACAATATACATATTAAGAATATCCCTGGGAGTATTTTGATATTTTTGCCTGGGTATGATGATATTATAACGGTTCGAGATAGAATCCAAAGTGATGCAAGATTTAATGGAAATGCCTATCAGATTTTCACGTTGCACAGTTTAATGCAGATCAGTGATCAACATAAGGTTTTTAATCACTTGCCGGATAAAAGAAAGATTATTCTGTCGACGAATATCGCGGAGACTAGCATCACTATCGATGATGTGGTTTATGTCATTGATTCGGGGAAAGTGAAGGAAAAGTGTTATGATTCGATAACTGGCATATGTAGCCTTCAAAGCGCTTGGATTTCGCAAGCATGTGCCAAGCAAAGAGCAGGTCGAGCTGGTCGTACTCAGCCTGGAATATGCTTCCACATGTTCTCGAAGTTTCGACACATCTCGATGCAGGAGTTTTCGACGCCAGAAATATTACGTATGCCCTTACATGAATTATGTCTCCAAACAAAAATGCTCGCGCCTAATGAGACAAGAATCGCCGATTTTTTGGCACGAGCCCTAGAACCACCATCCAGTATGGCTGTGAATAATGCTATTAAGCATCTTCTGGATATTGGTGCGCTTGACGAGAGTGAAGACTTGACCCTGTTAGGACAACATCTAGTCGACTTACCAGTCGAACCACGACTTGCCAAAATACTTATTTATTCTGTGATATTTAAGTGTATTGACCCATTGCTTACCATAGTGGCCTTCCTCAGCTATAGAGACCCCTTTGTTCTTCCTAGTGTACACCACCAAAAAAGTTCAGCTCAAAATATTAAGAAACAATTTGCCGTCGGTACATATAGTGACCATATGATCTTATTGCGTGTTTTCCAACAATGGCAGGACGCACGATTGTCGAATGGAGAGCGAGCGTTTTGTAGTAAATATTATGTGAGCTCTGCAACAATGGAAATGGTTGTGAATATTCGCTCACAACTCCTGGCTCAGTTGCGAGCGAGTGGTTTCGTCAAAACTAAACCACCGGGAGATATCCGAGAATTGAACGAAAATGCAAACAATTGGGCATTGATTAAATCTGTTTTGACTGCTGGATTATATCCGAATATTGCATTTATTAATAAGCACTCCATGCAAATGAGGACCAAAAATGAAAAGAAAGTGATGCTTCATTCAACGTCTTCGTTGCGAATGGGTGAACGTCATTCAAGTAACCAAGATCATATTCAAAGTTTAAAGACAATCCCGGCACCTTGGCTAATTTACGAAGAGCTATCTCGTACTGGAAACACGTACACAATACGGGCGGCTACATCAATCTCACCTTTAATAGTTGCCCTATTCGTGGACCACGCAACGCCAGACTATTCCGAACTACTTAGTTCGGATTCAGAGGACGAAGACTCAAGCAGCGCATTTCCCCTAAATAACTGGATCGTCTTCGAAGGCGCCACAGATATGATCCGCATTTTAACCGCTGTACGGGATAAGATCAACATACTCATCGCGAAAAAGATCTCTAATCCGTACAAATCCTACGGACCGCATGACGACGCGCTTATCACAATGATTGCGAATGTTCTTCAGTCTGAAGACAATGTAATCGGGTTCTTTCAGCCTCCCGGTATTGGACAACGTCCAAAAATTATGATGCCTAGCAACTATCCATCAGGGGGGTACAGCGCAACGGGGCGTTCGAACTCAAAAGGGCAAATCTCGAAGAAACAAGAGCGGATTGCGGCGGAAATATTGCATTTTAAGCGGGTTAATGTGAACAGTTATAATAAGTTCTTGTCGCGGGGTCCGGGGCCGCTAATACCGCATATACCGCAAAATAATCAATATAATTTAGAGTACAATTCTCATTATCCACAACCTTCATACATGCAATCTGAATTCAATCATTTAGCTCAAAATATAGATGCGTTATCGTTGTATAATAATGCGCCATATAACAATTTTGTCCCTTACAACTACTCGATGGACCCTAATATGTACTTACAGTCTCCATATATGGATCCAATATGGCAGGTACAAAGTGACTTCAGGAATAATGGCGTCACTGTTGATATGGAGGCTGGTGCATGCGCTTTGGAGCCTGTTCAGGTGGAGCATAGGCCTGAGCCGCAGTTTTTCAATAATATACCCCATGGACCGTCTTGGAATTTCCACTTGCGCGATCCGGAAAATACACTATTTTTCCTTATAAAAACAGGAAGTGTGAAAGCGATTGATGTATCCATCAGCAAGAAAACTTGGATCTTTTCGCCACAAACCGAGCGCAAAATTCTGCGTGAATTCCAGACTGGCCAGCCGATCATTTTGATATTCACCGTACAAATGTCGATTTTTTTCCATGGCATTGCCAGATTGATTAGCGGCCCATCCAAAGAGCTGTCGCATTATAACTTGAATTGCCCGATAGAGTGGTTGAGTCGGGCTGATATTCCGTTTGAACAACTAGGTGGGCTGATTTCACCAAACTGCTCCGATGGTGACAAATTGGACCCCAAAATAGGCATGAAATTGCTAATGATGTTCACTAACTGTACTCCGATCCAACCGGAACAAGTAGAAGGATGCATACCTTATGGTGGGTCAACGGAAAGATCGGATATACTTATCGATAGAAGAATTGCTAGAAATTCTTTGTTTAATCGCAGAAGAACCTCTACTTCTGCATGGGATACAGTATTATCAGATCTATTAATTTTCGGCGAATCTAAATCACTAACAATACAGCAAGTAAAGAAAAAATGGGATAATTTATGCTTCAAATATAAAAAAGAAAAACAGAATCCAGGCTCAATTTGGCCACATTTTTCAAAGATGAACGATTTTTTTAATAATGAAACTGGCCACTTTTTAAATGAAGACATTAATAAATGCTGTGTATCCGTACCAGAATGCTATGACAAAAAATTTACACAATTCAACCAGAATTGTGAAAAATATTGTCGAAATTTTGATCGATGGACGAAAAAGAAAACTTTATTTCTAATTGAAAGACGTAAAATACGAGATGCCTTGTTTGATGGACGAGGCTTGTCTGGATGGCAAGCTATTTTATCCGACTTTCAAGAAGAAGGCATTTCAACAGACATAACAGTGTACCATATTAAGAAAAAATGGGAGAATTTATGTACACGTTATAAAGTTATTAAAGATGCAAAACCGAACTCAAACTGGGAGTTTTTTAAAAAGTTGGATAAATTCTTTAAAGGGAAATCAACTAATAAACAAAATTTGAAAAGTGTGGATAATATAAAGCCTGAAACTGAAAATGTAGATTGGGTCGATGATTGGGACATAGAAGAACTTGTTAATAATGAAAGAGAAAAATTGTCTAAATGTCGATTATGTCAACAGAATAATAGTGATCATTCATTGGTTGATGATAAAAATCTTTGTGATCGTATAACAGCTTGTACTTCTATAAAAGTTCTTGAAGTAAACGAAAATCTACCAACTGGAATTTGCGACATATGTAAATCAACCATAGATAAATTTCACGATTTCCTTGTCCAATGTCACACAGTTGACAACGAACTACGAACTAGTATATCTGAGATAAAAATTAAACGAGAAAAAGAACAAATTTCCACTGATGTATATGAATGCTGCGAATGCCCCGTATCATTTTCAACTGTAGAATCACTTGAAAACCATTTAAAAAGTCACAAAATGGCATCTAGATTTCACTGCAAAATTTGCAGTGTTAGTTTCAGTCGGCAATCAGCGCTATATTCGCACATTAAGCGACATTTTGAAACCAACAATGTTCCTGTTAGCGAAGCAAATGATGAAACCAACGATTATTTATTTGAAGATGATCCAATTGATGGAAAGAGTGATAATGAGATTGAAAGTAGTACAACACAAATACCTAATTTATTCCCGTGTGAAGTTTGCTCTAAGGTGTTCGAGCGGGAGACTGATTTGCAAAGACATCTTGATACGCATTCGAGAACGATTCATGGTTGTCCGCGGGATGGTTGTGATAAAACTTATTTGAGTTTGACGTCGTTGCGAAATCATGAACGAAAACATTTAGGATTGCATTCGTTTCTATGCGTTATTTGTGGAAAAGGGTTTGTAACGAAAGTCGCCCTAAAACTCCACGAAAAAATTCATTCCGATTTAAAAGAGTACATCTGCGACGTTTGCTCCAGCGGCTTCTCAATAATGAGTAACTTAAGAGCCCATATTAAAAAACACCACGAAGGCCACAGATTTTATTGTTCGCAATGTCCCAAAGAATTTCTAACAAAATCGAGCTTGCAACGGCATGAACTAGTTCATACGGGTATTAAAGATTTTATTTGCGATACATGTAGCTCGGCATTTTATACAAATAAAGAACTGATCAAGCATAAACGGTATCATAACGGAGAACGATTGTACCATTGTAAACAGTGTTTTAAAACATTTTATGAAAAGCATCACCTTACGGTTCATATCAGGACCCATACTGGAGAACGGCCGTATGAATGCAAAGTTCCTGACTGTGGTAAAGCGTTTCGAGAAAGTAACAAGTTGGCGCGACATGTTAAAGTTATTCATCGGGTAATAAACTAG
Protein Sequence: MAPHRYTMNIIVSEEFRVQSEMILRNFLHDENVAAYEFPTNLTNIERAWLHNYAKTLGLSSKSIGKEPTRKITLSKPNAERGQQNRIPLTVSRENMTTIRDFFLRYPKNCGDGSKLRIRSKNNIEGTDTNMGQLTVGIPQLPVFSLCNDLIAFRMELPIWPMRDTLMEAIVSNQVVIVCGETGSGKTTQIPQFILDYSASVKEKTRIICTQPRRISAVAVAERVAAERGEKSGQTVGFHIRLESCVGPKTVLVYCTNGILLRTLMNGDACLNSFTHVIVDEIHERDRFSDFLLICLRECLVNYPHLRLILMSATMDVQSFQSYFNNAPVIFIPGRLHSVNEYYMEDILKITNYESATMTNLKKQHAKMVHLPVRPQTPIIQNYNMNLDLQFEMIDCINDCVEFGSDESFTQLLQLILSDHAPVNFQHPETMVTGLIAAAIHGNLNICTELLNYGADVKLVSKEKLTASDWARRNQHVDVVELLNHYDLYMENASTSNQCSISDDDKELLDLYHNTITDQLIDFDLLIVLLYNIHIKNIPGSILIFLPGYDDIITVRDRIQSDARFNGNAYQIFTLHSLMQISDQHKVFNHLPDKRKIILSTNIAETSITIDDVVYVIDSGKVKEKCYDSITGICSLQSAWISQACAKQRAGRAGRTQPGICFHMFSKFRHISMQEFSTPEILRMPLHELCLQTKMLAPNETRIADFLARALEPPSSMAVNNAIKHLLDIGALDESEDLTLLGQHLVDLPVEPRLAKILIYSVIFKCIDPLLTIVAFLSYRDPFVLPSVHHQKSSAQNIKKQFAVGTYSDHMILLRVFQQWQDARLSNGERAFCSKYYVSSATMEMVVNIRSQLLAQLRASGFVKTKPPGDIRELNENANNWALIKSVLTAGLYPNIAFINKHSMQMRTKNEKKVMLHSTSSLRMGERHSSNQDHIQSLKTIPAPWLIYEELSRTGNTYTIRAATSISPLIVALFVDHATPDYSELLSSDSEDEDSSSAFPLNNWIVFEGATDMIRILTAVRDKINILIAKKISNPYKSYGPHDDALITMIANVLQSEDNVIGFFQPPGIGQRPKIMMPSNYPSGGYSATGRSNSKGQISKKQERIAAEILHFKRVNVNSYNKFLSRGPGPLIPHIPQNNQYNLEYNSHYPQPSYMQSEFNHLAQNIDALSLYNNAPYNNFVPYNYSMDPNMYLQSPYMDPIWQVQSDFRNNGVTVDMEAGACALEPVQVEHRPEPQFFNNIPHGPSWNFHLRDPENTLFFLIKTGSVKAIDVSISKKTWIFSPQTERKILREFQTGQPIILIFTVQMSIFFHGIARLISGPSKELSHYNLNCPIEWLSRADIPFEQLGGLISPNCSDGDKLDPKIGMKLLMMFTNCTPIQPEQVEGCIPYGGSTERSDILIDRRIARNSLFNRRRTSTSAWDTVLSDLLIFGESKSLTIQQVKKKWDNLCFKYKKEKQNPGSIWPHFSKMNDFFNNETGHFLNEDINKCCVSVPECYDKKFTQFNQNCEKYCRNFDRWTKKKTLFLIERRKIRDALFDGRGLSGWQAILSDFQEEGISTDITVYHIKKKWENLCTRYKVIKDAKPNSNWEFFKKLDKFFKGKSTNKQNLKSVDNIKPETENVDWVDDWDIEELVNNEREKLSKCRLCQQNNSDHSLVDDKNLCDRITACTSIKVLEVNENLPTGICDICKSTIDKFHDFLVQCHTVDNELRTSISEIKIKREKEQISTDVYECCECPVSFSTVESLENHLKSHKMASRFHCKICSVSFSRQSALYSHIKRHFETNNVPVSEANDETNDYLFEDDPIDGKSDNEIESSTTQIPNLFPCEVCSKVFERETDLQRHLDTHSRTIHGCPRDGCDKTYLSLTSLRNHERKHLGLHSFLCVICGKGFVTKVALKLHEKIHSDLKEYICDVCSSGFSIMSNLRAHIKKHHEGHRFYCSQCPKEFLTKSSLQRHELVHTGIKDFICDTCSSAFYTNKELIKHKRYHNGERLYHCKQCFKTFYEKHHLTVHIRTHTGERPYECKVPDCGKAFRESNKLARHVKVIHRVIN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -