Basic Information

Gene Symbol
-
Assembly
GCA_002313205.1
Location
NNCF01135648.1:348153-395486[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 19 2.8 1.3e+02 2.9 0.2 1 23 245 268 245 268 0.93
2 19 0.19 8.9 6.6 0.0 2 23 298 320 297 320 0.94
3 19 1.4 65 3.9 0.2 3 23 325 346 324 346 0.96
4 19 1.6 77 3.6 0.6 1 12 377 388 377 393 0.82
5 19 0.017 0.8 9.9 0.4 3 23 509 530 508 530 0.95
6 19 3.1 1.5e+02 2.7 0.3 3 23 535 559 533 559 0.79
7 19 0.0019 0.088 12.9 2.5 1 23 1062 1085 1062 1085 0.96
8 19 7.3 3.4e+02 1.6 2.2 1 23 1099 1122 1099 1122 0.91
9 19 0.048 2.2 8.5 5.1 1 23 1128 1151 1128 1151 0.96
10 19 0.0024 0.11 12.6 1.9 1 23 1188 1211 1188 1211 0.97
11 19 0.0011 0.051 13.6 1.1 1 23 1217 1239 1217 1239 0.96
12 19 4.7e-06 0.00022 21.1 0.7 2 23 1246 1267 1245 1267 0.97
13 19 1.1e-07 5.3e-06 26.2 2.5 1 23 1272 1294 1272 1294 0.98
14 19 0.00034 0.016 15.2 4.8 1 23 1300 1322 1300 1322 0.99
15 19 2.7e-05 0.0013 18.7 4.8 2 23 1329 1350 1328 1350 0.96
16 19 0.00011 0.005 16.8 0.3 2 23 1357 1378 1356 1378 0.95
17 19 0.00034 0.016 15.2 0.3 3 23 1386 1407 1385 1407 0.95
18 19 8.4e-06 0.00039 20.3 0.5 1 23 1413 1435 1413 1435 0.97
19 19 0.00063 0.03 14.4 0.8 2 23 1442 1464 1441 1464 0.94

Sequence Information

Coding Sequence
ATGAGTGATGATGAAGCCAGAGACAGTTGCTTGGAGAGGACCAGCTTCCCGTTGTTCCACCCCAAGAAGAGCAAAATGTTGTCTCGGGCCAGTAGTACCTCCCACGAACCCTTGGCCACCACCAGACGAGGGGAAGTGGGACCACCGCCTGCCGCCACTCGAGACGCGGTGGAAACTTCTCACGACATGTTGAAACGGAGGCTGAGTCCGAACAATGCTTCATTAGCTTCCACGTCTAACACGATGGCAGTTCCCAGTGATGTGAGTGGGATCAACGCTTTTCTCATGAACCCTCTCTTGGCGATGGGCTTCCAGTTGCCTCAGTTGGCTTTGTTAatgcagcaacaacaacaacagaacaaGAAATCAgatcaccatcaccaccaccacctccatcgccaACAAGAGCAGCAGCTTCTGAGTGGTCTCCCTTCAGCCTCCTCTTCTCCTTCCTCCTCCTCGATGCTGAACCCAGCTCTCCTTCTCCCGCACATGTTGAGTGCTGAAAtagctgctgccgctgctgcacACCAGAAACCGCCGTGGTCCTCATACCACAGCACGGCTGAGAACGTTCTGTTGCCGGTTCAGACCAATGAGCCCAGAACGGGTACCATCATGAGTGGTTCTGTGGGCGGCAATGCGGTGCCTCATGTCTCAGTGAAAGGTTCTGCAGAGAAACAGCCCATTGTTGCTCATACGAAAGAGGATTCTGGACCGGGAAAACAGCCGTTTGTGTGCGACTTGTGTCGTGAGTGGTTCTTTTCCAGAGAGAAATTGGTGATGCATCTCGTCATGAACCACAAGATGCACCATTGTCATTTCTGTGCGGAACTGTTTGAGTCTGTTGAGATGCGAGACGACCACGAAGCGGGCACGCATTTGCCTTTGGAATGTGACATGTGTCAAGCGAGTCTGCCATCTGCCGATCTACTGTCGCAGCACTACCTCATTAGTCATGATGTTAGAAATTGCCAGTTTTGTGGTGTCCTGGTAAGGCCAAAGTCTTATTATGCTGTGCATGTTCGTAGGAAACACTTTGTAGCACCTGATGTTATGGTTGACGATTCTAAAGTGAGGATTATGCGTCGTTGGGATTCTGGAGCAAACGGGTCATCTGCGTGGACATTCACGTGCCATCTGTGTggcaaagaaaggaaaagaacaGAAACGTTtggtcatttttattcatatcatcGGCTTTCTCTTTCATGCCTCATCCAACTGTTGGCTTCCGAGGGAGTAGCGTTCTCTGTTCAAGGGACGCCGGCTCCGTCCTCTTCTGGTAACGTACAAAATTTGCCTGCCATAACGATGTCGAGCAGTGACTTCACCTTGACCGCTCCGGCAGGGGATGATTCTTCCAATAACGATGCCTCTCGTAACTCAGGGACCTCTGTAAGCGGAGATGAATCTCAACAACGTTGCCGTTCAAATCCTTCTTCTTGCACCGTGTGTACAAATCCATTTTCAGTCCAAGTGCCAAAACCTGCCCACGATCTCTTTTGCAGAGGGCTGACACTGTGTAGATACTGTGACAGAACGTTTCCCACGAAGGCTGCTAGAAATTCTCACGTCGCCAAGGATCACGGTGATCTCACATGCCGCGTTGGATGTCATTCTGACGTGTCATTTTCTCAGGAATATGAATTATCTGCTCATTATCTGCAAGATCATAATCTCCACATGTGCCATTACTGCACCAACCTCGTGCCAGACGTACAGAATCAGTTCcctcttcatttaaaaaaaatccacaaTTGTTCCGAGGATAGCAGCGCTCTTCAAGACCAGGGGAATAGTGGAGGAATAGATTTGTTTCAATGCAAATACAGTGGAGATAATCTTTCAGTTACATGTGTCTTGTGCAATATAGatattacttcatttatgaatgatatccaattattatttaaacacattGAATTCCACAGCATAGAAGTACAATCTGCTTTGCATCTTCTTGAAACAAATCTCATTTTTGATACTGAATTGTGTTCCAGCAAGACAAAGCGGAGTATAGAGCAAGATTTCAGGGATTTGAATTTACATCAGGGAAATACGTCTAGCTATTGGAATAAAATGTTGCACGGAGAAGAGGAGTCTAACAAAACAAGAAAGACTAGGACAAATACTAGAAAAACAGTCCTTAATGCAAAGAAAGTTGTTTATTCGAGTGACCAAGAGCAAGTGGTGTCGAAACAGAGAACCACTGTTCTGAAATCTGTGCAGCAGAATAAAGGGTCAGATGCTGAGGGATCGGTGACTAGAGGGATCAGGAAACATTCCAAAGAAACTTCGGAGAAGAACGGCGGTGATAAGGTCCCTTCAGGGACACCTTTAACAGATGATCCAAATTTTGATTCTTCTAGTGATCTAATGAGCTCTGAAGATGAAGATCTGGCGTCTGAAGGAGACGGCGCAGAGAACGATCTCACAGAGGAAGAAGACGACGAATATTCCCCTGAAAACAAGTCGAAACAGCTGTCAACTGGTCTTGAAAATGATAACTGTGAAGCTGAGTTTGACCCAAACGAAGTGGAATGTGTATTTACGGACACAAGCgatgaggaggaagaggaaaGGGAGACAGCTTTGGGACCtaaaattgaaatcaaagaaGAATGCAGTGTCGAAACCCATTGCACATTGCCTGTTTCAGAGTTTGAGGAAGTGGGAAGGACAGGAAGTTGTCCAAAAAAAGGAGACGATGTGCTCATCAAGAAGGAGCCGGAGGAGGAGGATGAATCTCAACAACCGAGAATTTCAGGGGAAGAGACAAGTGGTGGGTTAGTGGGGGACCAGTTGGTGGAGAAGAGAAATAGCAGCTGCACCACCACCAAATGTGAAATTTGTCAGGGCTCCTTCATCTCGGGTGAAGGGTCAAAGGAACTTGCCCACCACATGAGTTCTCTCCATGGCTTTTGCTTACCATCGGGTAGAGGCCTGGACAGAGCAGGAACCACTCGCCGAAGTTTGAAGTGTTGCTTTTGTCCGACGCAGACACTCTCCCGTCCTGCTTTGCGCCATCACCTGTCCCTGTTGCACAGCAGTGAAATGAAGAAGGAGCCTCCGGACAGGGAAGTGGCATATCAATGTCGTTACTGTGATCATCTTTTCTGGAGGGTGTCTGATCGTGATGAGCATCAAGTGGTCACGCATTCTGATCAAATATCCAGCTTCTTCAAATGCTACgtttgtttaaaagtttattcTAGTAAGTTGTGTTTGGAACGGCACATGAAAGCGGAACACCCTGATCAAACAAGGGGTGTGACGAATATCGGAATGACCTTTAAATGCAAGGTGTGTCTGACGATGCTGCACGGATTGTCTCTTCTAAGGCAGCATTTTCAAGATAAACATCCTGCATCTTTGGTTTTTCACTGTTATCGTTGTAACACTACATTGAAAACCAAGAAGACTCTACGCTCACACATTAAAAATGTCCATTCAGAGGCTCGCCGTCGCGAGTGCAACTTGTGTGGCAAGGTGCTCTGGAGCAAACGCGCTCATGCCATTCACTACAGAATGAAACATAGCGTGCATTCCAAAGTGGGCTTCAGGTGTCGCATTTGTCAAAAAAGATTTGACTCTAAGGATGAAAgGAAATTGCATTACCAAGTTGACCACGAGGGGGAAAGTCCATACCACTGTAGTGAGTGTGGCAAAGGTTTTGCATCTAAATCAGGAATGTATGGTCATCGTCAATTGCATACAGGATCAGGCATTTCCAAATGTGAATATTGTGGCAAAGAGTTTACGAGGAAAGATAGCTACAACGAACATCTGTTGATTCACAATGGTCCGAGGCACAAATGTCCTCACTGCCCCAAGGAGTTTGTGCAACGATCCAACCTTGTAAGGCACATAAGGATTCATACAGgtGAGAAGccttataaatgtttgtactgtgACAAATGCTTCTCCGACAAAGGGGCTTGCAATTCCCATATTCGTGTGCATACTCGAGAAGAAACTTGTAGCTGTCCTTATTGTGGTCAGACCTTCTCCAAGAAACAGAAATTGAAGTATCATATCCGAAAGCATACAGGGGAAGGTTTAATAAGTTGTGAAATTTGCAGCAAGTCTTTTACAAACAGCTTTGCTCTGAAAGAACACAGGGTAATTCACAACAGACAAACTCAAATTCTTTGCCAGATGTGTGGAAAAGGATTTAATAGTGAAAAGTATTTGCAACGGCATGTGACTATTGTTCATGAACCATCTAAAGCATTTGCCTGCCCTCTCTGTCCAAAGGTGTTCTCCCAACATGCACGTCTGAAGGCCCATCTCATGACACACACTGGAGTGAAGCATATCAAATGCTTGCTCTGTGATAAGGCGTACTCTGTTCGTAAATCATTACGGCGCCACCTTcaagaaaaacacaatatttccCCCGAACATCCTCAGTACAAACACTGTTTCTATGCCATGACTGCCGAAGAGGCAGGGCTACACATCCCAGAGGGAGCGGGACCCTTTGTCGGAGACGACGACTCGACGAGTCAATCGCTTCCTCaggacgaggaggaggagaagaagaagaaggtgaagaagagGGATCCTCCGTCTCCGACGTCGAGAAAGTTTCCTCGTAAAACCCCGGGACGAAAGGGACCTACCAGGAGAGGTGTTACCAAGACATCGGCCCCCTTTGAAGTATACAGTGGAGAAGCAGAGGAAGGAGACGGGGAACAGAAGAGAAACCGTCGAAGGGTGGGTAGGAAGCGCTCTTCTTCACAGCATCGCGAAGGGGAGAGCACGTCCTCCAACAATCCTTCGACGTCTTCCTCAGAATCTCCTAGGAAGAGAGGTCGACCTCCGAAAAAGATCGCTCCCACCAAAGTTGTGAGGAAACTGGATGAAGGAAAaaccgaagaagaagaagaagacgagagaGGCGAAGGAAATACCGAGTTTGTGCCTTCCGACGAGTCCGGTAGTAGCCAGAATTTGGCAGAATCTGTTTGTAGACGAGAAGAGGAGGCTGTAGTGACTAGGACTCCTGTGAAGGGGTTGAGTCGAGAGGACGGCAGGAGCACGGCAGCGTTAGCGACTCCACCGGGCGATCGCTCTACCGCCATCACGGCGATTAGCTCTTCGACCACAGGAAGAAAGAAGAGACGTGTGGAAGCGATTGTAGAAATCCTTCACAAGACTGGAAGTTCTCCCAGCAGTGTAAGTacaaaggaggaggaggaggaggaggaggaggatggggAAGATGACGAGGACCAAGAGGACAAGAAGGAAACTGTGACGACAAAGAAGAGGGAGGAAGAATCTAGTTTGAGAGGGGAATCTGAAAGTGAGGATGATACGCCAGTTTTAGCAAAGATTCTCCCCTTGAATAGTCCAAAGAAATCTCGAGATGAGTcttggtattttatttcaaatgtctcTGGAACCacgaaaggaaggaaggaaggtctTGTCTTGTCTTGTCTTGTCTTGTCTTCACCTGTTCCACAACGGCCTTCAATTGTTGTCGTTGACGCAGCGACAAGCAAACCGCCGTCTCAGCCGTCTCAGCCGTCTCAGCCGTCTCAGCCGTCTCAGCCGTCTCAGCCGTCTCAGCCGTCTCAGCCGTCTCAGCCGTCTCAGCCGTCTCAGCCGTCTCAGCCGTCTCAGCCGTCTCAGCCGTCTCAGCCGTCTCAGCCGTCTCAGCCGTCTCAGCCGTCTCAGCCGTCTCAGCCGTCTCAGCCGTCGACGAAGGAATCGCCGAATGGCAATGGAAAAGGAAGAGGCAAAGGCAAGGGCAAGGGCAAAGGCAAAAACTGTGGGGAGAGAGAGAGTCCAGCCAACCAGCCCAATTCCCCTGACTTCCCCCCACCACCATTGATGATAAGAGCGCGTGCGCGCCGTGTAAACTGCGCTGCTGTCTCAGTCGCAGCCACTGTGTGTCCCGGTGTGTTTCCTTctgccgcccgccgcccgccTGAGTTCGTTCGTTCAGTTGAGTTCCAGTCGCCGTCGCCATCGGAAGGGCGCTCGGTTCGCTACACGACGACCTCCCATCCGCAGCCGAGTCACGTATGTATTCGTTCAACAGATGAACAAGTGCTTATCGAGCGTTGCCAGGCGACGGGTGCGATAGCGAGTGGAAACATGTGCACTACGGAACGACCCTCACTTCTACGTCGTTAG
Protein Sequence
MSDDEARDSCLERTSFPLFHPKKSKMLSRASSTSHEPLATTRRGEVGPPPAATRDAVETSHDMLKRRLSPNNASLASTSNTMAVPSDVSGINAFLMNPLLAMGFQLPQLALLMQQQQQQNKKSDHHHHHHLHRQQEQQLLSGLPSASSSPSSSSMLNPALLLPHMLSAEIAAAAAAHQKPPWSSYHSTAENVLLPVQTNEPRTGTIMSGSVGGNAVPHVSVKGSAEKQPIVAHTKEDSGPGKQPFVCDLCREWFFSREKLVMHLVMNHKMHHCHFCAELFESVEMRDDHEAGTHLPLECDMCQASLPSADLLSQHYLISHDVRNCQFCGVLVRPKSYYAVHVRRKHFVAPDVMVDDSKVRIMRRWDSGANGSSAWTFTCHLCGKERKRTETFGHFYSYHRLSLSCLIQLLASEGVAFSVQGTPAPSSSGNVQNLPAITMSSSDFTLTAPAGDDSSNNDASRNSGTSVSGDESQQRCRSNPSSCTVCTNPFSVQVPKPAHDLFCRGLTLCRYCDRTFPTKAARNSHVAKDHGDLTCRVGCHSDVSFSQEYELSAHYLQDHNLHMCHYCTNLVPDVQNQFPLHLKKIHNCSEDSSALQDQGNSGGIDLFQCKYSGDNLSVTCVLCNIDITSFMNDIQLLFKHIEFHSIEVQSALHLLETNLIFDTELCSSKTKRSIEQDFRDLNLHQGNTSSYWNKMLHGEEESNKTRKTRTNTRKTVLNAKKVVYSSDQEQVVSKQRTTVLKSVQQNKGSDAEGSVTRGIRKHSKETSEKNGGDKVPSGTPLTDDPNFDSSSDLMSSEDEDLASEGDGAENDLTEEEDDEYSPENKSKQLSTGLENDNCEAEFDPNEVECVFTDTSDEEEEERETALGPKIEIKEECSVETHCTLPVSEFEEVGRTGSCPKKGDDVLIKKEPEEEDESQQPRISGEETSGGLVGDQLVEKRNSSCTTTKCEICQGSFISGEGSKELAHHMSSLHGFCLPSGRGLDRAGTTRRSLKCCFCPTQTLSRPALRHHLSLLHSSEMKKEPPDREVAYQCRYCDHLFWRVSDRDEHQVVTHSDQISSFFKCYVCLKVYSSKLCLERHMKAEHPDQTRGVTNIGMTFKCKVCLTMLHGLSLLRQHFQDKHPASLVFHCYRCNTTLKTKKTLRSHIKNVHSEARRRECNLCGKVLWSKRAHAIHYRMKHSVHSKVGFRCRICQKRFDSKDERKLHYQVDHEGESPYHCSECGKGFASKSGMYGHRQLHTGSGISKCEYCGKEFTRKDSYNEHLLIHNGPRHKCPHCPKEFVQRSNLVRHIRIHTGEKPYKCLYCDKCFSDKGACNSHIRVHTREETCSCPYCGQTFSKKQKLKYHIRKHTGEGLISCEICSKSFTNSFALKEHRVIHNRQTQILCQMCGKGFNSEKYLQRHVTIVHEPSKAFACPLCPKVFSQHARLKAHLMTHTGVKHIKCLLCDKAYSVRKSLRRHLQEKHNISPEHPQYKHCFYAMTAEEAGLHIPEGAGPFVGDDDSTSQSLPQDEEEEKKKKVKKRDPPSPTSRKFPRKTPGRKGPTRRGVTKTSAPFEVYSGEAEEGDGEQKRNRRRVGRKRSSSQHREGESTSSNNPSTSSSESPRKRGRPPKKIAPTKVVRKLDEGKTEEEEEDERGEGNTEFVPSDESGSSQNLAESVCRREEEAVVTRTPVKGLSREDGRSTAALATPPGDRSTAITAISSSTTGRKKRRVEAIVEILHKTGSSPSSVSTKEEEEEEEEDGEDDEDQEDKKETVTTKKREEESSLRGESESEDDTPVLAKILPLNSPKKSRDESWYFISNVSGTTKGRKEGLVLSCLVLSSPVPQRPSIVVVDAATSKPPSQPSQPSQPSQPSQPSQPSQPSQPSQPSQPSQPSQPSQPSQPSQPSQPSQPSQPSQPSQPSQPSTKESPNGNGKGRGKGKGKGKGKNCGERESPANQPNSPDFPPPPLMIRARARRVNCAAVSVAATVCPGVFPSAARRPPEFVRSVEFQSPSPSEGRSVRYTTTSHPQPSHVCIRSTDEQVLIERCQATGAIASGNMCTTERPSLLRR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-