Lko_22938-RA
Basic Information
- Insect
- Laupala kohalensis
- Gene Symbol
- -
- Assembly
- GCA_002313205.1
- Location
- NNCF01129566.1:248971-264161[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.016 0.77 9.9 0.0 2 23 407 428 407 428 0.95 2 12 0.0015 0.071 13.2 7.2 1 23 434 457 434 457 0.97 3 12 0.85 40 4.5 2.0 2 19 474 491 473 493 0.91 4 12 0.018 0.85 9.8 0.5 1 10 500 509 500 522 0.84 5 12 1.7e-06 7.8e-05 22.5 1.0 2 23 529 551 528 551 0.95 6 12 0.00042 0.02 14.9 2.8 1 23 557 579 557 579 0.96 7 12 0.0002 0.0094 15.9 0.8 1 23 585 607 585 607 0.98 8 12 2.2e-05 0.001 19.0 3.1 1 23 613 635 613 635 0.96 9 12 0.032 1.5 9.0 0.5 1 23 646 671 646 671 0.91 10 12 2.5e-07 1.2e-05 25.1 0.4 1 23 689 711 689 711 0.98 11 12 4.8e-08 2.2e-06 27.3 0.3 1 23 736 758 736 758 0.98 12 12 2.4e-05 0.0011 18.8 1.6 1 23 764 786 764 786 0.95
Sequence Information
- Coding Sequence
- ATGGTAAAGAGTAAATTACCTCATGAAGGTAGATGTAATGAAAAGGTGGGTGAGACGAAGTTAAAAGTGGAAGAACTTAATGAATGTGAGTCCAATAAGTCTACAgATGATGATGCTTCTCTACCTGATCATGGAACAGTACCAGAAGAATTTGATGAAATGGAGAATCAGTCATCACAAATATTGTTACATTGCCTTGTTCCAGAATGTGGTAAATCACAGGCTGATTACCCTGATAAAGTATTTTTCATGTTGCCTTCAGATGAAGAAAAGTTACATCATTGGCTTCTTGTTTGCAAACGGACTGACttgataaaagattttaaaaatatctgtaatgAACCGTATGGTATTTGTGAGGATCACTTCATTACTGATAATTTTTCTGACAGCTCAAAGCAAACATTAAAGTATGAAGCAATTCCTACCCTGTTTACCGATAACCAAAGAGGAGAGGACTCAAAAGACAGACATGTGTTTTTACCAGGAGAATGTGAAATACGTATTAAAGAAGAATTACCTGATGAATGTGATGACTACTTCTATGGAGAAAAtgagatggaagaagaggaagatgaaaatttaaatcttcTTTGTCGTTTGTGTGCCAACAGAATCCGTGATGTTGTGTATATATTTAATGACACCGGACAAGAACagcaaattgcaaagaaaataaacactTGCTTGCCAGTAACAGTGAGAAGAACAGATCCGTTACCTAAGCAATTATGCAAGTCCTGTGTTGCAAAGCTTAACTTGTTTCATGAATTTGCTGAAGCTTGTATTAAAGCTGAGGACAAACTATTGAACTTGAATGGGAATGATTATTTTAGGTCTGAGGCCGTCTCGTCAGCGAGTTCTGAATGTATTTCCAACAACTACAACTTGAGGAgctttaaaaaagatgaaaaatttaactGCTCCCAAAGCCATGACTCCAATTCGAAGAACGAGACCAAACCGGCAGATTTGCAGCGAGATAAGAATTATTGTTGCCCCTTATGCTGCAAAGGAAGTATGACGTTGACAGATCACGAACCACCGAGTCCTGCGGAACTAGACGGTGAAACAGTGAGAGGCTGTGATTCCGACTTTCTTCACAATGGGTATTCAGATGGAACTGATAATGGCAGCTTGAATTCTGAATTGAAACAAGAACCATTATCCCAGTCGGGTCTCGGTACAAGCGCCGTCATCGAGGGAAGCAAGAAGGCCGTTTGTCGGATTTGTGGCGAATTCTTTGAAAATGCGGACGCTGTAATTTCTCACGCAACTTcgcattttgaaactgatttctTTCCGTGTTGCTTGTGCGATCTATGTTTTTCTACGAAATCGAGCTTTAAAGAACACACCAAAAAACAGCACATTGAGAACGAGAGACAAGGAGCGAAAGTTCGACCGACGAAGCGATTGACGTGCAATTCGTGCGGGAAGCTGTTCAATTCCGAACGGACCTTCAACGGCCACTCGTGCGGCAGTTCCCCTCGTCCCTTCAAGTGCAACGAGTGCGGGAAGAGCTTCCTGACGGAACTGCGCCTCTCCTTCCATCAGCAGATCCACCAAGGAGGCAGCAACATGACCTGCGAGCATTGCGGCAAAGTGTTCTCTCGGGAGAACAACCTGTTCGACCACGTGCGCCTGGTGCACATGGGGGAGAAGGCGCATTGTTGCGACCTGTGCGGCAAGACGTTCCAGCTGAAGGCGCGGCTCATCGCGCACCAGCGCGTGCACACCGGCGAACGGCCCTTCGAGTGCGACATCTGCGGAGGCAAGTTCTACGACAAGGCGACGCTCAAGGGCCACCACCTCACGCATCTGAACGTGAAGCCCTTCCAGTGCGAGAAGTGCGGGCGGTGCTTCGCGCGCAAGACGCTCTTCAAGCAGCACGCCATGGCGCACCTCAACGAGGAGCGCAAGCGGCCCAGGACGTACCGCTGCCGCATCTGCGGAGGCTCCTTCGTCTTCAACTCGTACGCCAAGCTCATCGAGCACCGCAGGGAGAAGCATCCGCACGTGGAGATCAAGGAAGTAGACGAACCCACGCAAGGGACGAAGCCCTTCAAGTGCGACGAATGCGGGAAGTCGTTCGCGTATCGAGTCACGTTGATCGCGCATCAACGCAACCACACGGGGGAGTTGCCTTTCCAATGCGATCACTCGTATTATCAGCACATGTGGATCCATCAAGGGAAGAAGCCGTATCCGTGCTCTTATTGCGGCAAGGCGTTCCGACGCTCCAACGGATTGAAAATCCACATTCGCATCCACACTGGGGAAAAGCCACACGCGTGTGACGTATGTGGCCGTTCATTTGCCCAGAAACAAGACATGAAGAAACACAGGAACCTCCATGTGATTGGGAAATTG
- Protein Sequence
- MVKSKLPHEGRCNEKVGETKLKVEELNECESNKSTDDDASLPDHGTVPEEFDEMENQSSQILLHCLVPECGKSQADYPDKVFFMLPSDEEKLHHWLLVCKRTDLIKDFKNICNEPYGICEDHFITDNFSDSSKQTLKYEAIPTLFTDNQRGEDSKDRHVFLPGECEIRIKEELPDECDDYFYGENEMEEEEDENLNLLCRLCANRIRDVVYIFNDTGQEQQIAKKINTCLPVTVRRTDPLPKQLCKSCVAKLNLFHEFAEACIKAEDKLLNLNGNDYFRSEAVSSASSECISNNYNLRSFKKDEKFNCSQSHDSNSKNETKPADLQRDKNYCCPLCCKGSMTLTDHEPPSPAELDGETVRGCDSDFLHNGYSDGTDNGSLNSELKQEPLSQSGLGTSAVIEGSKKAVCRICGEFFENADAVISHATSHFETDFFPCCLCDLCFSTKSSFKEHTKKQHIENERQGAKVRPTKRLTCNSCGKLFNSERTFNGHSCGSSPRPFKCNECGKSFLTELRLSFHQQIHQGGSNMTCEHCGKVFSRENNLFDHVRLVHMGEKAHCCDLCGKTFQLKARLIAHQRVHTGERPFECDICGGKFYDKATLKGHHLTHLNVKPFQCEKCGRCFARKTLFKQHAMAHLNEERKRPRTYRCRICGGSFVFNSYAKLIEHRREKHPHVEIKEVDEPTQGTKPFKCDECGKSFAYRVTLIAHQRNHTGELPFQCDHSYYQHMWIHQGKKPYPCSYCGKAFRRSNGLKIHIRIHTGEKPHACDVCGRSFAQKQDMKKHRNLHVIGKL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -