Lko_01306-RA
Basic Information
- Insect
- Laupala kohalensis
- Gene Symbol
- ZFX
- Assembly
- GCA_002313205.1
- Location
- NNCF01127331.1:76033-83606[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 15 0.33 16 5.8 0.0 2 23 6 27 5 27 0.95 2 15 1.5 70 3.7 2.9 1 23 634 657 634 657 0.91 3 15 0.0022 0.1 12.7 0.5 1 23 755 778 755 778 0.97 4 15 0.016 0.77 9.9 0.2 1 23 783 805 783 805 0.98 5 15 5.4e-05 0.0026 17.7 3.2 2 23 808 829 807 829 0.97 6 15 2.4e-06 0.00011 22.0 0.9 1 23 835 857 835 857 0.99 7 15 6.2e-05 0.0029 17.5 3.8 2 23 864 885 863 886 0.95 8 15 1.3 63 3.9 5.3 5 23 899 917 898 917 0.96 9 15 4.8e-06 0.00022 21.0 2.3 2 23 923 945 922 945 0.97 10 15 0.023 1.1 9.4 0.2 2 23 961 981 960 981 0.96 11 15 8.1e-06 0.00038 20.3 2.1 1 20 987 1006 987 1009 0.92 12 15 0.0052 0.24 11.5 5.5 1 23 1017 1039 1017 1039 0.98 13 15 0.0039 0.19 11.9 3.5 1 23 1045 1067 1045 1067 0.98 14 15 1.7e-06 7.9e-05 22.5 4.1 1 23 1073 1095 1073 1095 0.98 15 15 0.0013 0.062 13.3 7.6 1 23 1101 1123 1101 1124 0.96
Sequence Information
- Coding Sequence
- ATGGATGCCCCAGTGCCCTGCCCTGTATGTACGTTGTATCTACGTGAGGGGGTTTCATTGCAAAACCATTTGAATACCCACCCGAAAGACCAGGTTATCGAAGCACTGCTGAAGTACTGCGGATCGGTACGTGATGTGAATGCACCTGGTGAAATAGAAGGGGTTGTGGACGGTCAGTATGAAAGTCAACAGAACGACCAAACTGTAGCAGAAAATGCTTCTTCATCAATTTCCAGTCAACAGCCATACCCCTGTGGAAGTAGTCACTTCACTGCTGCTGTTACATATCAGCAGTTTATGAGTAGCAATGCTTCTGTTGGAGGTACTGTACTACCGCAATGTTTCTCAGTTCCTGCAATAATTACTACTCCTGCTGGAGAACCTGGTCAGGCTACAATAATGCCGCTGCTATATAACCCTTATGTCAttcaacaacagcaacaacaacttCAGTTTTATAATGCATTTCGAACTATTCCTCAGCAACCTTTATCTCGTCAAATTGTATCTCCTTCTCCTCTTTTCCCAGTTTCTCCTCAATTTGCTGTTACCACATCTGGGAATCCTATTTATCAATCCAGTATGTCTTCCAGTTCTGCTTTGCAAAATGGAGAAAATATACCATCCAACCCTGCCATATATGTTCCATCGGTTGGCACTCAGGATGATGATTTGAAATGTAATGATCAAGAAGTAACCTGTTCTGAAGATTCTCCCAAATGCAAAGCTGATCAAACTAAACCTAAAATATCGAATATTCAGTGCATTGAAAATGAAGATGTTACTGAAACTCGGGAATCTGAACCCAAAGTAGGTGATGAATGTGATAACTCAGTAATATCTGTTGTTTTTGAAGATGATGTGAATAATGTGAGTGAGGTTCCTGTTGCAAATGGTGATAAAAGTAGCCCTGGTACTAGTATTGAGTATGATGATGtagtttgtgaaattaaaattgattctaATGAAAAATTACCTGAAGGTGAAGAAAGCTGCTCTGGTGAAAATGATGCAAACAGTCATTTAGGAGATTCACTATCCAGTCCTGTCAGCCCAAGTGTACACATCAGAGTAGATCTCAATAGAACCAATCCTTGTACAAGTGAAAGATTTCTTGATGGAAACGGCAACAGTAGAGGTCTCACATCCATGGAAGGTgagaccccagaagataatggaGCTACTTCATTGTCAGAAGACAAAACTGACAATGTGGGATGGGGATTTATTTCTGAGAAAGATAAAGTAAACTCTGAATCACATTCAGATGagaatgtgaaagaattttctgAGTTCATTATTTCAGACCTTTATCCTTCAAATACAGAACCTAAAAATTCTGATCAAACGACTTCTCTTTCTCGTGGAACACAAGATGGTGATACATCTGCTAGGCATTTCAAGGTTGTTGACATAGAAGGCATGCAAGTTTTGGTGGCATCACATTTACTAGCACCAAGTCAAGAACAGAATGCAGATGATGATGTAGAACATCCTGCAAGAACACCCAGTGAACAGAGTAGCTGTGAGGCTCCTCAAGACTCAGAAGAAGTGAGTACAAATGTGAATCCTGACATTCAGACTGATGAAGTTATGCCAGCCATGGGAGAACTTTCAGGTCAGGAAAGCATAGGAGAAAATGACACAAATTCTTGGTCTCAGgaaaaagatGATATTACAACATCCTATGACCTTCTTGCACGAGAGAAGTGGGAGGTGTCTGATGGTTCTGATGAAGAAAATGAAGCAGACGGTGATATTGGAGACATGGGTGTAGACACTGAAGAGAGTCCATGTGATGTGTCACCTTCAGAAACTCTTCCACTTCCTACTGCTAGTTCAGTAGAAGACCAGTATAGAGaagataaaactaaaaagaaagagaaaccaaagtgtttttataaatgttgGACATGTAATCAAATCTTTACTTGCCCCAAAGAGCGCAGAGTGCATCAAAGTGAAAAACATGGTGCTAGGGGTCTAGAAAGACTAGAATCTAAAGTGGGAGGGCTGAAAAATTCTTCTTGGCCCATTGTAAAGATTGAAGGCAGTCAAACTGTGGATAGTACAATGAAACAGgaggaaaaagaggaaaaagtttGTTTGAAATCTGAAGAAGATACATTGTCAAACATTCCAGAGGAAATAGATGAAAGCAAGACAGCTGGTGAAACAAAAACCTCTTCATTTGAAGAAGAAtgtgtgaaagaaataaaaaaggaagaggaaCAATCAAAACCTGATGATAATGCATTTAAGTTTATTTGTTCAAGGTGTGAAGGGGTCTTTGCATCTGCCAAAAGTCTTCATCAACATGTACGCACTGCTCACGGGCAAAGTCAATTCACGTGTCGCACTTGTAGTGAGAAGTATCCCTCTGAGGCTGCCTACTTGGCTCATCTCAAAGTTCATCCATTAGAATGTTCGAGATGTGGAAAGTACTTTTATAGACATCAGAATCTAAATTTGCATATAAGAAGACATCTGGGCATAAAACCATTTAAGTGTACTATATGTGATAAAGCATTTGTTACCAAACAAAAACTTGCTGAACACACTAACACTCACACGGGTGATACTCCTATTAAATGCAATCTTTGCACAGAAACATTTCGACGATATAGCAATTTAATACAACATAAGAACAGACATCACttgaagataaaaaagaaaattaaggatTTTATTTGTCACTGTGGGGAAGTTTTTCATTCGCAAAAGAAACTGCATTGGCATAAGGAAATACATGATGAAAAACCAAAAACGTGTAATTACTGTAGTGAGCGTTTTGTACATGCATCAAGTCTCACTAGGCACATTCGGAAAGCCCATGACCAGCGTTATTTTCCATGCCAGGGTCGTGAGAGAGAGAATGTTGAGTGTCCAATTTGTGGGTGTATTTTTCTGAAGTCATCTTTGCCAGTTCACATGCGTTTGCATAGTGGAGAACGTCCATACAACTGCCATATTTGTGGTAAAAATTTCAGTACTAAGTGGAATCTGCAACTGCATCGTTGGACACATGCCTCACGTAGTCTAAAGCCATACAAATGTTCCCTGTGCAAGAGTGCTTTCATTCGTCATAGCGAATACACTTCGCATATGCATTCCCATCGTAATGTTAGACCATACACATGCAATTATTGTGGTAGCCAATTTATTCGGAAGTATAACTGTATACGTCATGCACGTGAGCATGAAAGTGAGAAACCATTTGTTTGCAATATTTGTCAGAAGTCATTTCATCGTCGTTACTATTTGAAAGAACATATGCGGATCCACAGTGGACTGCGGCCTTTCACTTGCCATATATGTGGGAAAACTTCAAGTACGAAGTCGAATCATAATAAGCATGTTAAAATTCATCACGCTCGTGAGGCTGTTAACACTGAAGGTTAA
- Protein Sequence
- MDAPVPCPVCTLYLREGVSLQNHLNTHPKDQVIEALLKYCGSVRDVNAPGEIEGVVDGQYESQQNDQTVAENASSSISSQQPYPCGSSHFTAAVTYQQFMSSNASVGGTVLPQCFSVPAIITTPAGEPGQATIMPLLYNPYVIQQQQQQLQFYNAFRTIPQQPLSRQIVSPSPLFPVSPQFAVTTSGNPIYQSSMSSSSALQNGENIPSNPAIYVPSVGTQDDDLKCNDQEVTCSEDSPKCKADQTKPKISNIQCIENEDVTETRESEPKVGDECDNSVISVVFEDDVNNVSEVPVANGDKSSPGTSIEYDDVVCEIKIDSNEKLPEGEESCSGENDANSHLGDSLSSPVSPSVHIRVDLNRTNPCTSERFLDGNGNSRGLTSMEGETPEDNGATSLSEDKTDNVGWGFISEKDKVNSESHSDENVKEFSEFIISDLYPSNTEPKNSDQTTSLSRGTQDGDTSARHFKVVDIEGMQVLVASHLLAPSQEQNADDDVEHPARTPSEQSSCEAPQDSEEVSTNVNPDIQTDEVMPAMGELSGQESIGENDTNSWSQEKDDITTSYDLLAREKWEVSDGSDEENEADGDIGDMGVDTEESPCDVSPSETLPLPTASSVEDQYREDKTKKKEKPKCFYKCWTCNQIFTCPKERRVHQSEKHGARGLERLESKVGGLKNSSWPIVKIEGSQTVDSTMKQEEKEEKVCLKSEEDTLSNIPEEIDESKTAGETKTSSFEEECVKEIKKEEEQSKPDDNAFKFICSRCEGVFASAKSLHQHVRTAHGQSQFTCRTCSEKYPSEAAYLAHLKVHPLECSRCGKYFYRHQNLNLHIRRHLGIKPFKCTICDKAFVTKQKLAEHTNTHTGDTPIKCNLCTETFRRYSNLIQHKNRHHLKIKKKIKDFICHCGEVFHSQKKLHWHKEIHDEKPKTCNYCSERFVHASSLTRHIRKAHDQRYFPCQGRERENVECPICGCIFLKSSLPVHMRLHSGERPYNCHICGKNFSTKWNLQLHRWTHASRSLKPYKCSLCKSAFIRHSEYTSHMHSHRNVRPYTCNYCGSQFIRKYNCIRHAREHESEKPFVCNICQKSFHRRYYLKEHMRIHSGLRPFTCHICGKTSSTKSNHNKHVKIHHAREAVNTEG
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -