Basic Information

Insect: Laupala kohalensis
Gene Symbol: ZEB2
Assembly: GCA_002313205.1
Location: NNCF01125908.1:301841-323733[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 23 7.1 3.3e+02 1.6 0.3 8 23 115 131 114 131 0.90

2 23 0.32 15 5.8 0.4 2 23 139 160 138 160 0.96

3 23 0.0045 0.21 11.7 1.2 1 23 164 186 164 186 0.97

4 23 0.00051 0.024 14.6 2.3 3 23 196 216 195 216 0.98

5 23 0.026 1.2 9.3 0.1 2 23 220 241 219 241 0.96

6 23 0.082 3.9 7.7 1.4 2 23 319 341 318 341 0.93

7 23 0.028 1.3 9.2 1.4 2 23 346 367 346 367 0.98

8 23 1 48 4.3 0.5 1 23 404 426 404 426 0.76

9 23 0.052 2.4 8.3 0.7 2 23 435 456 430 456 0.86

10 23 8.5e-07 4e-05 23.4 1.1 2 23 461 482 460 482 0.98

11 23 3.1 1.4e+02 2.8 4.7 1 21 491 511 491 513 0.95

12 23 0.31 15 5.9 0.5 1 13 519 531 519 535 0.90

13 23 1.1e-05 0.00052 19.9 0.8 1 23 600 623 600 623 0.96

14 23 4.3e-05 0.002 18.0 0.7 1 23 629 652 629 652 0.96

15 23 0.8 37 4.6 1.0 3 21 796 814 795 815 0.91

16 23 0.061 2.9 8.1 0.8 2 23 821 843 820 843 0.94

17 23 0.00056 0.027 14.5 8.0 3 23 1117 1137 1115 1137 0.97

18 23 0.0021 0.098 12.7 1.0 1 23 1143 1165 1143 1165 0.98

19 23 0.00022 0.01 15.8 1.2 1 23 1171 1193 1171 1193 0.97

20 23 0.00071 0.033 14.2 0.0 1 17 1199 1215 1199 1216 0.93

21 23 0.00074 0.035 14.1 5.4 1 23 1231 1253 1231 1253 0.94

22 23 0.0043 0.2 11.8 3.6 1 23 1259 1281 1259 1281 0.97

23 23 0.018 0.85 9.8 2.4 2 21 1289 1308 1288 1309 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	23	7.1	3.3e+02	1.6	0.3	8	23	115	131	114	131	0.90
2	23	0.32	15	5.8	0.4	2	23	139	160	138	160	0.96
3	23	0.0045	0.21	11.7	1.2	1	23	164	186	164	186	0.97
4	23	0.00051	0.024	14.6	2.3	3	23	196	216	195	216	0.98
5	23	0.026	1.2	9.3	0.1	2	23	220	241	219	241	0.96
6	23	0.082	3.9	7.7	1.4	2	23	319	341	318	341	0.93
7	23	0.028	1.3	9.2	1.4	2	23	346	367	346	367	0.98
8	23	1	48	4.3	0.5	1	23	404	426	404	426	0.76
9	23	0.052	2.4	8.3	0.7	2	23	435	456	430	456	0.86
10	23	8.5e-07	4e-05	23.4	1.1	2	23	461	482	460	482	0.98
11	23	3.1	1.4e+02	2.8	4.7	1	21	491	511	491	513	0.95
12	23	0.31	15	5.9	0.5	1	13	519	531	519	535	0.90
13	23	1.1e-05	0.00052	19.9	0.8	1	23	600	623	600	623	0.96
14	23	4.3e-05	0.002	18.0	0.7	1	23	629	652	629	652	0.96
15	23	0.8	37	4.6	1.0	3	21	796	814	795	815	0.91
16	23	0.061	2.9	8.1	0.8	2	23	821	843	820	843	0.94
17	23	0.00056	0.027	14.5	8.0	3	23	1117	1137	1115	1137	0.97
18	23	0.0021	0.098	12.7	1.0	1	23	1143	1165	1143	1165	0.98
19	23	0.00022	0.01	15.8	1.2	1	23	1171	1193	1171	1193	0.97
20	23	0.00071	0.033	14.2	0.0	1	17	1199	1215	1199	1216	0.93
21	23	0.00074	0.035	14.1	5.4	1	23	1231	1253	1231	1253	0.94
22	23	0.0043	0.2	11.8	3.6	1	23	1259	1281	1259	1281	0.97
23	23	0.018	0.85	9.8	2.4	2	21	1289	1308	1288	1309	0.92

Sequence Information

Coding Sequence: ATGGCCTCTGAAGCGATTGATATATTACTTCCAGACAAGTCTGCTGGTGAACTAACTTTGAAAAAAAGTGTTGTGAATAACATGGAAGAAGTAGGAGAGTATGTAGAATCAAGTGATAGTATTGATAATATTCATTCTACAGTGGATAATCCTGGTGtgagaaatatagaaattatttgtgAGCCATTATGGAATTCAATTAGCCCAGTTACCCATATTGAAATTATCAAGTCAAATTCTAGGAGAGTTACAGGTGCAAACCGTGTTGTTCCACTTCTAACTAATACCTTAAAAGCGGGCAAACTTGCTGTAACAAATTCTGGACTTGCTGAAcTAACCAGgaagaaatatgtttttcaagaaCAGCTGAGGGACCATTTGAAACAAATACATGGTATTCATTGCCCTGACCTTATATGCAAACTTTGTTTTATGGAATTTGGTACGAGCATAGAACAGAAAGCtcatgaaagaaaacatgaacagtCATTTGTTTGTTACATATGTTCGGAAACATTTTCAATGGATTATTTGTATCAGAAACATTTGAaccaacatttaatattacaagaaaatacaaaagactGTAAAAAATGTGGTAGAAGATTTAAGACCAGTATTTCCCTGGACATTCATAAGAAGAGACATGTATATATTGAATGTACTGTATGTGGAAGTGTTTTCAATAATGACCTAGACTTATTAATGCACTTAAAGAACCATGAAACAGGTGGagttgtgaaatttttaaatttagtggagcAATTTGATCATGATGAAAATTTACTAGAAGCAATGCTTGCTTCATactcaacaatttcaaaaagaaaaacctTGAGTATTGCAGAATCTGAATGTTCTACTTTAAtgaaagatgtttctgactgTTTATCTGATATTGTCACTGTCGTGTCACAAAATAATAGGACTGGTACTGATGAGAGACTGGGAATTGAATGTAAGTTGTGTGGAAAAAATATGTCATCTAATACAGAGCTTTTGGAACATAGGCACAACTTTCATTTAAGAAATCGGACTTGTCCTTTTTGTGGTAAAAGGAATAGATCTGTTAGCCAAACTTGGAGACACATGAAGTCTCATATTGTGAAGAACAAGAATTCTGCTTTGAAACATCTGCCTGATTCTCAAGATTTAGTCGAAGAGTctagtattacaaaaattaaacaacCTCGAACCAATACAAGACTATATAGTTGTAACATATGTTCTAGAAAATTTCTGTACCCTGGATCTCGTGACAATCATGTTTTGCAACACAGCAAAGATAAGTGTGAAAGCTGGAAGTGTATTGTTTGTGAAGAAGTGTTTTCGCACCCAGGATTACTCATGTCACATTCATCCGTTCATAATCCATCTGTGAAATGTAATGTGTGTGACAAGGTATTCTCATCCCAACGTTCCCTGCAGAGTCATTTGAAATCCCATTCCAACAATGAGAAGAAAAGAAGACACAAGTGTAGTTTTTGTTCTGTGGAATGCCCAACTCTTTTTGGACTCCAAGCTCACATCCGTTGCCACACTGGAGAGAGACCTTATACTTGTGGTCAGTGTCAAAGAAGATTTAAGCGTCTccagCTCACtaaagagaatgaaaggaaagaaatagatAAGTTTCTTctGAAAAGCaaagttttgaaatacttttgGCATATGTACCTGTATGAAGTTGATGATAGACACCTGCATAGACCCCTGTGCGAAATTGATGAATACTTTACTAGTGTTGCTGTGAAAAAACATATCCAGGTTGTTCATAACAGCGCAAGTTTGGAGTATCATTCCTGTTCAATTTGTCCGAAAACATTTAACAGTCCTGCAAACATGATTCGTCACTACCTTAGAATTCACTGTCATGTTCGTCGTTTTGTTTGTGGGATATGTGGATCCCGATTTAGCCAAAACCAAGACTTACGACGCCATTTTAAAGTGTCCCATGAACTAGACATGCCAAATATAAATGGCACAGAcaggaagaaattgaaagagatttatgtgattCCCAGTATTGACAATTTACCTGAAAAACATCCACATGCCATTAAGATTAACTCTATAGTTGCTGAAGAAAAAGCAAAATTCAAAGGATTGTCAGAGTTAATGACAAAGAGAAATGTTGATCGGGAAGATTCACAAGGAGTATTGAAGAGTATAGGTCAGTTTATCCAAGAATTTTCAACAGAAAATGAAGAGCAAGTCATCGAGTTAGTCCCAACATCATCTGGCAGAATTAACGAGGCAATGATTGACGCATCAGTTTCTGATGATAATCATGAATGTCCACAGAATAGCATATTGACAAAAGAGAACAATGCAAATGAAATGCTAtttgcaaataatgaaaaaagcaatttcaaagtgatattatgtaaaatttgtgGCAAAAATTGTTTTGGGGAGAAGGAGTATTTAAAACATACTGCTACTggtaatatttccatttcatgtAGCCAGTGTGAAACTAGATTCTGTGATGATGTCTTACTTGCATATCACATGtcaaatgaacacaaaattgtttCTCACAATAGTGAcgaagtattttctaaaaaagataatattttgcaGGATTCATATGTAAATGAAGGTCAGTCTTGGAAACATTTTATGGATGAACAGATTTGCACATTAGAGCAGAATAATTCACTACTTGTAACAcctggtgaaaatatttttactattgtgcCTGATCCAACTATACATTTAGATACCATTTCCTCAGAAAATATTCAATCTGTTTCGCCAAATTCTCAGACAACTCGGACAAGTGATGCTCATATACCTACATCTCTTAATATTAATGGatttgttgtacaaaatataatttttcagcaGGCTCCGGCAATTTTGCAAACAGTTCCACTTACATTTTCTAATCATGAAGTGATGAATTCATCTGGTATCTCTCCTGTTTTAACCCTAAATTCTGTACCTGTTGTATCTGACTTGCAAACAAAACCATATTTACTCAACATGACTAAAAGTCAAAAAATGACTTCAGTGAATGAAACTAATTTAGCTAAGTTTACCTCAAAAGATGTCATGGATTCACGCAAAGATACATCAGTTGATGAGACTAACGAAAACTGTGGAAATAACCATTCAAAAGAATGTGAAGTTAACCTTGAGAATAACATTGAATTATCCAATTATAATAGAGAAGAGAGATTGAAAGTAATCATTGATACATTAACCCATGAAGGACCTAATGAGGAAATGGTAAATGATGAATCCAAGGAAGCAAATTGTGAACGAAGTAGAGAAAGCATTCAggatatttttccttcaaatggAGACAAGAAGCATAGTGCtggAACTAAGCCATATGGTTGTCATCATTGTGGAAAACACTTTTCTGAAAAGTGCAATTTGAAAGTGCATTTAATGGTACACACTGGAGAACGTCCATTTACGTGTGAAGAATGTGGTAAACGGATCAGATATAGAAAAGATGTTTTGGATCATAAGAGAATGCATTTGGGTGAAAAACCATTTTCATGTGATGAATGTGGACGTAAGTTTCTCAGGAAAAGAGAATTGAATcgtcataaaattattcatactgGTAAGAAAAAGCATAAATGTCCAATTTGTGGCAAAGCTTTTGCCAGATTGGATCTGTTGAAGCTGGGTCATTTACCCACACATATTGATGACAAATCAAAGCTGTTGCACTCTTGTAGCATTTGCCACAAGAGTTTTAAGTTAAAATCAAAGCTAAAGCAACATGAAATATTGCATTCAGgCCTTAAGGAGTTTCAGTGTGACATATGTCATAAGCAATTTGCATTAGGGTCTTATCTGAGAACACATTTACACTTGCATTTGAAGAAAGATAAACACCTGAAGTGTAATATATGTCATCATCAATTTGCTACGAATACAGCATTTAAGtcacaCAAAGAGACTTGTCTACAAATACCTACAAAAAACAAGAATGGAAAACTACTGAAGGATTTCCCTGctgttattcaaaatattcttattgaaaAAGGAAATGCAGAATTGGAAACTGGAATTGGAAGAGATATTGAACTGCAAGATGTGGACCTGAGTATGTTGGATGCCGATAGTTGTAATGCTGTGATATATCTTCAAATGACTCCTGAAGATTTAAAACTAAGTTTTGGAAGTAGTGATGATTAA
Protein Sequence: MASEAIDILLPDKSAGELTLKKSVVNNMEEVGEYVESSDSIDNIHSTVDNPGVRNIEIICEPLWNSISPVTHIEIIKSNSRRVTGANRVVPLLTNTLKAGKLAVTNSGLAELTRKKYVFQEQLRDHLKQIHGIHCPDLICKLCFMEFGTSIEQKAHERKHEQSFVCYICSETFSMDYLYQKHLNQHLILQENTKDCKKCGRRFKTSISLDIHKKRHVYIECTVCGSVFNNDLDLLMHLKNHETGGVVKFLNLVEQFDHDENLLEAMLASYSTISKRKTLSIAESECSTLMKDVSDCLSDIVTVVSQNNRTGTDERLGIECKLCGKNMSSNTELLEHRHNFHLRNRTCPFCGKRNRSVSQTWRHMKSHIVKNKNSALKHLPDSQDLVEESSITKIKQPRTNTRLYSCNICSRKFLYPGSRDNHVLQHSKDKCESWKCIVCEEVFSHPGLLMSHSSVHNPSVKCNVCDKVFSSQRSLQSHLKSHSNNEKKRRHKCSFCSVECPTLFGLQAHIRCHTGERPYTCGQCQRRFKRLQLTKENERKEIDKFLLKSKVLKYFWHMYLYEVDDRHLHRPLCEIDEYFTSVAVKKHIQVVHNSASLEYHSCSICPKTFNSPANMIRHYLRIHCHVRRFVCGICGSRFSQNQDLRRHFKVSHELDMPNINGTDRKKLKEIYVIPSIDNLPEKHPHAIKINSIVAEEKAKFKGLSELMTKRNVDREDSQGVLKSIGQFIQEFSTENEEQVIELVPTSSGRINEAMIDASVSDDNHECPQNSILTKENNANEMLFANNEKSNFKVILCKICGKNCFGEKEYLKHTATGNISISCSQCETRFCDDVLLAYHMSNEHKIVSHNSDEVFSKKDNILQDSYVNEGQSWKHFMDEQICTLEQNNSLLVTPGENIFTIVPDPTIHLDTISSENIQSVSPNSQTTRTSDAHIPTSLNINGFVVQNIIFQQAPAILQTVPLTFSNHEVMNSSGISPVLTLNSVPVVSDLQTKPYLLNMTKSQKMTSVNETNLAKFTSKDVMDSRKDTSVDETNENCGNNHSKECEVNLENNIELSNYNREERLKVIIDTLTHEGPNEEMVNDESKEANCERSRESIQDIFPSNGDKKHSAGTKPYGCHHCGKHFSEKCNLKVHLMVHTGERPFTCEECGKRIRYRKDVLDHKRMHLGEKPFSCDECGRKFLRKRELNRHKIIHTGKKKHKCPICGKAFARLDLLKLGHLPTHIDDKSKLLHSCSICHKSFKLKSKLKQHEILHSGLKEFQCDICHKQFALGSYLRTHLHLHLKKDKHLKCNICHHQFATNTAFKSHKETCLQIPTKNKNGKLLKDFPAVIQNILIEKGNAELETGIGRDIELQDVDLSMLDADSCNAVIYLQMTPEDLKLSFGSSDD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -