Lko_12590-RA
Basic Information
- Insect
- Laupala kohalensis
- Gene Symbol
- Zfy1
- Assembly
- GCA_002313205.1
- Location
- NNCF01130566.1:513725-545422[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 19 0.079 3.7 7.8 0.7 3 23 82 102 80 102 0.92 2 19 0.00011 0.0052 16.8 2.4 1 23 109 131 109 131 0.98 3 19 0.00046 0.022 14.8 1.5 1 23 137 160 137 160 0.98 4 19 3.4 1.6e+02 2.6 0.3 1 14 166 179 166 188 0.69 5 19 0.0048 0.23 11.6 4.1 1 23 194 216 194 216 0.97 6 19 0.00025 0.012 15.6 2.3 1 23 220 242 220 242 0.99 7 19 8.5e-06 0.0004 20.3 2.5 1 23 252 274 252 274 0.96 8 19 2.7 1.3e+02 2.9 0.9 3 12 282 291 280 299 0.70 9 19 0.00018 0.0084 16.1 5.4 1 23 305 327 305 327 0.98 10 19 3e-07 1.4e-05 24.8 1.7 1 23 333 355 333 355 0.98 11 19 1.8e-05 0.00086 19.2 1.8 1 23 423 445 423 445 0.98 12 19 0.0021 0.097 12.8 0.6 2 23 452 474 451 474 0.95 13 19 0.00017 0.008 16.2 0.4 1 23 480 502 480 502 0.98 14 19 3.3e-06 0.00016 21.5 2.9 1 23 508 530 508 530 0.97 15 19 1.6e-05 0.00075 19.4 3.1 1 23 534 556 534 556 0.98 16 19 0.53 25 5.2 0.2 1 19 566 584 566 585 0.82 17 19 0.33 16 5.8 1.6 2 23 605 626 604 626 0.97 18 19 1.5e-05 0.00068 19.5 1.9 1 23 633 655 633 655 0.99 19 19 0.013 0.62 10.2 0.1 1 17 690 706 690 707 0.93
Sequence Information
- Coding Sequence
- ATGCGGAAGAAAGGTCAAGAATTTGCAAAATCATATGAGAACACATACGAGAGAAAAGTcttttcaatGCCCTCTTCGCTCATTGACCCTACAGTTGGTAATCCGAAGGAACCAATAAGTATGACAGACACGAATAAAGTAAATATCAACTCAATACGTTTGAATTTGGATGAAGATAGTTCGAATTGGGTTCCACAAACAAGTCCGGATACACAAGAAAATGGTGACACggagaatataaaatgtattttttgtggcTCTTGTTTTGGATCGTTTTGGATGCTCGAAGAACATATGAAGATTCATGACGAATTTCGAAGGATATACAAGTGTGAAGTGTGTAATAAAGAATTTCTAAAGAAATCCTATTTAACTAAACATTTATCTTCTCATTCCATCGATCGGCAGTTTCAGTGCGACGTATGTTTTAAAACGTATAAGAATGAAACTGTTTTGAAGGACCACAAAAGAAGCGTTCATTTAGGTGAAAAGCGTTTCGTTTGTGACATTTGTGATTATGCTGCATACAAGAAGGATATTGTAGATCTTCACAGAAAAAGACACCTTAAACAGTATACTCACATTTGTGATGTATGTAACAGAGGGTTTTATGCAAGCCACCAATTCAAAGTACACACGAAAACACACAGAGAAGGTTTTAAGTGCGACATATGTTTCAAGCTTTTCCAAAGTGATAGTAATTTATTAAGGCATAAAAATACTCATGAACCCAATTACAAAAGTAATTATGATCACGCGTGTAGTGTATGCGGTAAGAAGTTTCGGACGAAACTATCTCTTAAGAGGCACGTGTTAAGTCATGTGGGTGGAAGTGGAAAGATATGTGAATTATGTGGAAAGACGGTCACTGATTTGCCAAGTCATCGCAGAACACATACGGGAGAAAAGCCTTATGAGTGTTCTTACTGTGAAAAGAAATTCTCTACACGAAAGAGCCTGAAATGTCATTTACGTGTACATACCGGCGAAAAGCCATTCTCTTGCGAGACATGCGGAAAAACGTTTACCCAACAATCTACTCTCATTGTTCACAAGCGATATCATACTGGAGAACGACCTCATGAATGTGACTTTTGTAAGAAAAAGCCTTCTTCGCTCATTGCCCCTACAATTAGCAAACCAAAGCAGCCAATAAGTATGAAAAACAGAAACTTAAATGTCAATTCGAAAAGGTTGAATTTGAGTGAAGACATTTTGAAACGGATAAGAAGACACTTGAGGGGCCATGTGGATTTGCACCGGGTATTCAAGTGTGGAGTGTGTGGtaaagaatttcaaaagaaaaccctTTTAACTAGACATTATTCTTCTCATTCAACTGAACGGAATATTGAGTGCGCCATATGTAATAAGAAGTTCAGGACTGAAAGTATTCTAAAGGATCACTTCAAAAGAATTCATTCTGGCGAGAAACgtttccaatgtgaaatttgtgattaCTCTGCATTTGATAAATACGCGCTAGAAGTTCACAGAAAAAGACACCTAAAGCAATATACTCACATATGTAACGTATGTAACAAAGGGTTTTATACAAAAAGCGATCTGAATAAACACGAGAAAACACATACTGGGGGTTATAAATGTGACATATGTTCAAAGTTCTTGAAAAACAAGTCTAATTTGACTAATCATAAGAAGTTACATGATCCCGATTATAAAAGTAAAAGTGATCATGTGTGCAGTATATGCGGTAAAATTCTTCTGACTAAAATACGTCTCAAGCAGCACCTTTGGGAATTAGAATTCCCGAAACTATCGGAAAACACAAGAAATGACACTGACATTGTAAAATGTCTTATTTGTTGCACGTCTTTTGATTCATACCAACTCCTAGAAGAACATAAAAAGATCCATATAAATTCACGCCGGGTGTACAAGTGTGACGTATGCAATaaagaatatagaagaaaatcgCTTTTCCTTGATCATTTAACCACCCATTCGATTGATTGCCCATTTGAAAGTGACGCGTGTTGTAAGAAATTCAGGATTGAAACTTTTCTAAAGGATTTCATCAAAAGAATTCATTGTGGCGAGAAGCGTTATGAATGTGGCATTTGTGATTATGCTTTTTATCACAAGTGGAGTTTAGAAGCGACACCAGAAGCAATATACTCACATTTGTGA
- Protein Sequence
- MRKKGQEFAKSYENTYERKVFSMPSSLIDPTVGNPKEPISMTDTNKVNINSIRLNLDEDSSNWVPQTSPDTQENGDTENIKCIFCGSCFGSFWMLEEHMKIHDEFRRIYKCEVCNKEFLKKSYLTKHLSSHSIDRQFQCDVCFKTYKNETVLKDHKRSVHLGEKRFVCDICDYAAYKKDIVDLHRKRHLKQYTHICDVCNRGFYASHQFKVHTKTHREGFKCDICFKLFQSDSNLLRHKNTHEPNYKSNYDHACSVCGKKFRTKLSLKRHVLSHVGGSGKICELCGKTVTDLPSHRRTHTGEKPYECSYCEKKFSTRKSLKCHLRVHTGEKPFSCETCGKTFTQQSTLIVHKRYHTGERPHECDFCKKKPSSLIAPTISKPKQPISMKNRNLNVNSKRLNLSEDILKRIRRHLRGHVDLHRVFKCGVCGKEFQKKTLLTRHYSSHSTERNIECAICNKKFRTESILKDHFKRIHSGEKRFQCEICDYSAFDKYALEVHRKRHLKQYTHICNVCNKGFYTKSDLNKHEKTHTGGYKCDICSKFLKNKSNLTNHKKLHDPDYKSKSDHVCSICGKILLTKIRLKQHLWELEFPKLSENTRNDTDIVKCLICCTSFDSYQLLEEHKKIHINSRRVYKCDVCNKEYRRKSLFLDHLTTHSIDCPFESDACCKKFRIETFLKDFIKRIHCGEKRYECGICDYAFYHKWSLEATPEAIYSHL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -