Lko_12591-RA


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Laupala kohalensis
Gene Symbol
-
Assembly
GCA_002313205.1
Location
NNCF01130566.1:545469-563868[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 1.3 60 4.0 0.2 6 14 84 92 83 93 0.90
2 18 0.12 5.8 7.2 0.6 2 23 149 170 148 170 0.96
3 18 2.7e-06 0.00012 21.8 3.5 1 23 177 199 177 199 0.99
4 18 0.00031 0.015 15.3 1.7 3 23 241 261 240 261 0.98
5 18 0.61 28 5.0 0.5 3 12 269 278 267 286 0.72
6 18 0.00012 0.0059 16.6 5.1 1 23 292 314 292 314 0.98
7 18 0.08 3.8 7.7 0.6 1 12 320 331 320 334 0.89
8 18 0.0086 0.41 10.8 0.2 2 23 379 400 378 400 0.97
9 18 6.2e-06 0.00029 20.7 2.5 1 23 407 429 407 429 0.99
10 18 9.1e-06 0.00043 20.2 2.6 1 23 435 458 435 458 0.97
11 18 9.6e-05 0.0045 16.9 0.3 1 23 464 486 464 486 0.98
12 18 0.03 1.4 9.1 0.8 1 23 492 514 492 514 0.96
13 18 4.4e-05 0.0021 18.0 3.9 1 23 518 540 518 540 0.99
14 18 4.5e-06 0.00021 21.1 0.5 3 23 552 572 551 572 0.99
15 18 0.057 2.7 8.2 0.2 5 23 579 597 578 597 0.73
16 18 9.6e-06 0.00045 20.1 1.2 1 23 603 625 603 625 0.99
17 18 4.3e-07 2e-05 24.3 0.5 1 23 631 653 631 653 0.98
18 18 0.00029 0.013 15.4 1.5 1 21 659 679 659 680 0.95

Sequence Information

Coding Sequence
ATGAAAAAACATACTGAAGGTTTCAAGTGTGATATATGGTGCAAGTCTTTccaaagtaaacaatatttatcacACCATAATCCAaattatataagtaataataGCAATAACTTGTTTGATATATGCGAACACATTCAGGAGAAACGCCATATGAATGTTGTTTCTGTGAAGAAGAAAAATCGCTTCAAAAATTGGTCTTATGTCATTTACGTGTACATACTGGAGAAAaacttttctcttgttttctcATGTGGAAAAACATTTACTCAACAGTACTCCTCATTCTTTGACCATGCTGTTACGAATCCAAAGGAAATTAAACGcatgaaaaagattaaaaacttaaatatcttgtCAAAACTATTGAAAATGGATGAAGATAGTTTCAATTGGGTTTCCCAAAAAAGACAGCAAAAACAAGAAAGTACCGAGTGTGGAAATGTAAAATGTCTTATTTGCTGCTCATCTTTTGAGACATACGAGTTACTAGAAGAACATATAAAGATTCATAAAGATTCACGCCGGGTATTCAAGTGTGAAGTGTGTAACAAAGAGTTTCGAAGAAAATCACTTTTACATGATCATTTATCCACCCATTCAAATGATTGTCCATTCGAGTGTGACGTATGTTGTAAGAAATACAGAAATGAAACTAAACGAAATTTATTGTACCATAAGAAGACACATGatccaaattataaaaacaatagtaatattttgtgtgatttaTGTGGTAAATGTTTCCCGACGAAAATGCGTCTGGGTAGGCACCTGGAGACACATAGAGGTGGACACAAAAAGATATGCGATATTTGTGGGAAAACAGTCACACATTTGCCAAGTCATCGCAGGATACATACGGGAGAAAAGCCATATGAATGTTCTTTCTGTGGAAAAAAATTCAGCAAGCAATACAGCCTGAAATGTCATTTACGTATACATACTGGCGaaaagccattctcttgtgagaCATGTGGAAAAACGTACTCTTCCATTGATACTACTGTTAGGAATCCAACtgaaccaaaaattataaaaaacacttATAAATTGAGTATCATCCCAAAACAAGTGAAATTGGTTGGATATAGCGGAAAAAGTCggaaaacacaagaaaatgacACTGACATTATAAAATGTCtgatttgtttttcatcttttgaCTCATACCAGCTCCTAGAAGAACATATAAAGATCCATACGGATTCACGCCGGGTATATAAGTGTGAAGTGTGTAATAAGGAATATCGaagaaaatcactttttcgtGATCATTTAACTACTCATTCAACTGAGTGTCCATTTGAATGTAACGTGTGTtctaagaaattcagaaataaaacttttctaaaGGATCACATCAAAAGAATTCATTCTGGCGAGAAGCGTTATGAATGTGACATTTGTGGTTATGCTTCTTATAACAAGTGGAGTTTAGAACTTCACAGGAAGCGACACCTAAAGCAATATACTCACATATGTGGTGTATGTAACATGGGGATTTATGGAAATTACCAATTTAAACAGCACATGAAAATACACTCTGGAGGTTTCAAATGTGATATATGTTTCAAGTCCTTCCAAAGTAGCCAATATTTATTACGCCATAAGAAGACACATGatccaaattataaaaataataataataacttgtgTGATTTATGCGGTAAAGGTTTCCCGTCGAAAATATATCTGAGGAGGCACCAGAATACTCATAAGGGTGGAAACAAAAAGATATGTGATGTATGTGGAAAAACAGTCTCTGATTTAGTAACTCATCGCAGAATACATACAGGTGAAAAGCCGTATGAATGTTCTTTTTGTTCAAAGATGTTCTCTGCGAGATCATACTTAACCGCTCATACTCGGGTACATACCGGCGAAAAGCCATATTCTTGTGAGACATGTGGAAAAACGTTTACGCAACAATCTCCTCTCATTATCCACAAGCGAATTCATACGGGAGAACGTCCttataaatgtgatttttgtgaaaAAGAGTTCGTTTCTAAGTCTCTCATGAATACTCACAGGAAAAAATGCCAAATCTAA
Protein Sequence
MKKHTEGFKCDIWCKSFQSKQYLSHHNPNYISNNSNNLFDICEHIQEKRHMNVVSVKKKNRFKNWSYVIYVYILEKNFSLVFSCGKTFTQQYSSFFDHAVTNPKEIKRMKKIKNLNILSKLLKMDEDSFNWVSQKRQQKQESTECGNVKCLICCSSFETYELLEEHIKIHKDSRRVFKCEVCNKEFRRKSLLHDHLSTHSNDCPFECDVCCKKYRNETKRNLLYHKKTHDPNYKNNSNILCDLCGKCFPTKMRLGRHLETHRGGHKKICDICGKTVTHLPSHRRIHTGEKPYECSFCGKKFSKQYSLKCHLRIHTGEKPFSCETCGKTYSSIDTTVRNPTEPKIIKNTYKLSIIPKQVKLVGYSGKSRKTQENDTDIIKCLICFSSFDSYQLLEEHIKIHTDSRRVYKCEVCNKEYRRKSLFRDHLTTHSTECPFECNVCSKKFRNKTFLKDHIKRIHSGEKRYECDICGYASYNKWSLELHRKRHLKQYTHICGVCNMGIYGNYQFKQHMKIHSGGFKCDICFKSFQSSQYLLRHKKTHDPNYKNNNNNLCDLCGKGFPSKIYLRRHQNTHKGGNKKICDVCGKTVSDLVTHRRIHTGEKPYECSFCSKMFSARSYLTAHTRVHTGEKPYSCETCGKTFTQQSPLIIHKRIHTGERPYKCDFCEKEFVSKSLMNTHRKKCQI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-