Basic Information

Insect: Lathronympha strigana
Gene Symbol: Mecom
Assembly: GCA_949128165.1
Location: OX421927.1:2417864-2446167[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.074 6.5 8.7 0.5 1 23 816 839 816 839 0.98

2 13 4.2 3.7e+02 3.2 0.0 2 23 847 868 846 868 0.94

3 13 1.2 1e+02 4.9 0.5 1 23 872 895 872 895 0.96

4 13 0.23 21 7.1 6.7 2 23 901 922 900 923 0.94

5 13 0.00013 0.011 17.4 0.0 1 23 926 949 926 949 0.96

6 13 0.0058 0.51 12.2 0.3 1 23 954 976 954 976 0.98

7 13 5.2 4.6e+02 2.9 0.1 6 20 988 1002 984 1004 0.88

8 13 5.2 4.6e+02 2.9 0.1 6 20 1087 1101 1083 1103 0.88

9 13 5.2 4.6e+02 2.9 0.1 6 20 1167 1181 1163 1183 0.88

10 13 5.2 4.6e+02 2.9 0.1 6 20 1247 1261 1243 1263 0.88

11 13 0.0016 0.14 14.0 1.2 3 21 1275 1293 1273 1297 0.91

12 13 0.00015 0.013 17.2 0.1 1 23 1302 1324 1302 1324 0.98

13 13 1.9 1.6e+02 4.3 0.1 3 13 1336 1346 1335 1347 0.86

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.074	6.5	8.7	0.5	1	23	816	839	816	839	0.98
2	13	4.2	3.7e+02	3.2	0.0	2	23	847	868	846	868	0.94
3	13	1.2	1e+02	4.9	0.5	1	23	872	895	872	895	0.96
4	13	0.23	21	7.1	6.7	2	23	901	922	900	923	0.94
5	13	0.00013	0.011	17.4	0.0	1	23	926	949	926	949	0.96
6	13	0.0058	0.51	12.2	0.3	1	23	954	976	954	976	0.98
7	13	5.2	4.6e+02	2.9	0.1	6	20	988	1002	984	1004	0.88
8	13	5.2	4.6e+02	2.9	0.1	6	20	1087	1101	1083	1103	0.88
9	13	5.2	4.6e+02	2.9	0.1	6	20	1167	1181	1163	1183	0.88
10	13	5.2	4.6e+02	2.9	0.1	6	20	1247	1261	1243	1263	0.88
11	13	0.0016	0.14	14.0	1.2	3	21	1275	1293	1273	1297	0.91
12	13	0.00015	0.013	17.2	0.1	1	23	1302	1324	1302	1324	0.98
13	13	1.9	1.6e+02	4.3	0.1	3	13	1336	1346	1335	1347	0.86

Sequence Information

Coding Sequence: ATGAATGGAAGAGTGTTGGATGTGGTGTTGGCGAGCATGGATATGAGTGACACTGTGTGCGTGCGGCAGGTTGACCCGCAAGAGGTGCTGTCCAAAATTGATCCTCATCATCCACCCATTATAGCTCGAATCCTATATAGTTTCACGTCAAGGGCAGTAGGTACTAATGGAACCTTCCAACCTGAAAATCCGACCCAATTCTGGTCCCATGTTAGTTCGCTTCGCTGCAAGGGTGGGGTCGAACCAAAGGTCACGCTCGGGGGTGTTGAATACTCAGGCGCTAGTGCCGCCGCAGCATTCGGAACGTATTTCGCTTCAGTTTTCTTGGCGGATCGGCCGATTCTAGACCCACAAGTAGCTAGCGCGTGTCCCCCAGCGGACGCTCGTCGCGTCGATATCAGACGGCTTAGCGAGCGTGACGTTCGGCTCGCAATCAAGAAACTTAAACCACGGGCGTCACCTGGACCTGATGCAGTACCCGCGTTCGTGCTCAAGGCTTGTGTCGATAATCTAGTCGCtccaattaaatttatttttaaccttattCTACAAACTGGAGTTTATCCGACTGCGTGGAAAAAGTCTCGGGTGACGCCTATTCCAAAGAAAGGATCGAAGttgaaaatagaaaattacCGACCTATTGCGATTCTTAGCGCTATAGCTAAAGTCTTTGAATCGGCTTTACAAAGTGCCTTGCTTCCCCAATGCCTGCCTAACATCACCAGCGCACAGCACGCCTTCTTGCCAAAGAGGTCCGTAGTAACGAACCTGCTCACCTTAACGCGGATGGTATCTCAGGAGTTAGATAGGAAAAATCAAGTAGACGTTATCTACCTAGACTTCCAGAAAGCCTTCGACCGTGTCGACAATGACATTCTTCTTTTAAAACTAGGAGCCATGGGATTTACACCCAGACTCCTGAAACTGTTTTCGAGTTATCTCTCGGATCGAAAGCAATTCATAAAGTATGGCCCTTACGTATCCGAGTGTTATCTCACGCGCTCCGGTGTTAGCCAAGGATCTAACCTAGGACCACTGCTTTTCGTGTTGCTCATAAACGACCTACTCGACGAGGTGCGCGGCTCCATGGTGTTGTTGTTCGCTGATGATGTGAAGCTGGTTAAGGTGATTCAAAGCCAGAGCGACTGCGTGGATTTACAAATGGACATTGATGTAGTGTACCGATGGAGTCTCCGTAATAAGCTTTATTTCAACGCGGAAAAATGCGAAATGTTAACATTTACACGTTCGAATACTGCCAACGATTATCAATACAATATTGGTGACGTCCCAATAGCTCGTGTGGAAAGGGTTCGCGATTTAGGTGTCATTTTTGATCCGGGGCTCACGTTCCGCGATCACATTCAAGCTGTCACCAAATCCGCATCGGGGAGGCTAGGATTCGTCTTGCGCAATTCTGCACCGTTGACCGTCCACGCTACTCGCGTGTTGTATACGGCGCTCGTCCGCAGCGTGCTGGAGACGAATGCAGTGGTTTGGAGTCCACATGAGAGCAAATATACTCTTATGTTGGAACAGGttcagaaaatgtatttaaggGCGCTATACAAGAGGATACACTTCTATTACCCATATATGTACCCTACCCTATTCTTGCAAGGTCAGTTAGGCTATGACTCCTTGCAATTGCGTAGATTAATTGCTCTAGCCAAATTCAGTATAGATGTCGTGAGAGGAAAGATCGATTGTGTAGATCTCGTCGAAGCATTCGTGCGTCTTTGTGTCCCTAGCTGGTACATCCGCGCGCGAAAGCACCCCTTGTTTGCGGTGCCGGGATCGCGCACACAGGCTCACGCGCACAAATCGCACAATCCAATCACACGCGCGCTAGCGTTCCTCAACTCCGTGCACGAAGCGCACCCGCAGTGTGATCTGTTTGCGAGTTCGACGGGGCGACTGATGATAGAGTGCAGGAAGgcTGAACCAGCTAAGAAAGTTGTGTGCTTAGAGTGCCACAATGTCCTGAAGAGGATAGAAACCTTCCGCCAGCAAGTGCTGAAGAGCTTCCAGAGCTTGACTGAGCAAGTTCCATCTTTAACACCCCAAAACTCCGACCAATCTAAAAAGAAAACCAACTTGACACACAAAAAAACAGTAAACATATACCTACCACCAGCGAAAGCAACGCCACTCACCGAGAAATGGCAACCCACGCCACCGCCACAGATAAGCAAAGAAAATGTGAAGAAAGAGGAGTCTATGGAGCCGGCGTTGCCAGTGGTGAAAATTAAGGCAGAGCCGCTTGACAGTGAGAGGGAGACGATTGAGATTGAGATTGTGCCTGTGAAGAAGCAGGAGGAAgtcaaagctcGTCCAGACAAAACGACCAACGTCGCCGTTCGAACGGTCACGCTTACCAAAGAAGAACTCGTGCTCGAGCGTTTAAAACTCGCGCAGTCTGCGGCCTACCTTAAACTCCCATATCGCTGCGAAAGCTGCGTGGTCGGGTTCAACTACGAGGAGAACATTAGGGACCACATGAAGAGGAAACATGGTCCGaaagtgGGCAGTGTGACCTGTGACGTGTGTCTCGCCGTGCTGCACCCTCCCGGAAGCCTTGCTGCGCACATGTTCCGACATCTCACGAGGTACGAATGCGTGAAATGCGACGCGCGCTACGGGAACTATGACGACGCGCTGTACCACTACAAGAAGCAACACGGCGAGCCCTGTCTGCGGTGCAGCGAGTGCCACTACACCACCGActCCCCGCAAAAGTTCAGGAAGCATAAACGTCAACACCACAAGCGGTTCACATGCAAGGACTGCGGAGTGGTGCTGGCCACGCGGCCCAGCCTCACCAGGCATATGGCCGTGCTGCACAACAAGCGGCTGTACCGCTGCGTGCACTGCTCCGTGACGTACACGGACGGCGCGGCGTTCGTGGCGCACATGCGGCTGcacggcgcggcggcggcgcgcgcgcactgCGCCCCGTGCGGCGTCTCCTTCAAGGCGTGGCACGCCTACAACGCGCACGTGCTCTACAGCGCGCAGCACCAGCACCAGCGCAAGTTAGTGCTACTGTTCGTGTTGTGTACAGTTCGTGGCGCACATGCGGCTGcacggcgcggcggcggcgcgcgcgcactgCGCCCCGTGCGGCGTCTCCTTCAAGGCGTGGCACGCCTACAACGCGCACGTGCTCTACAGCGCGCAGCACCAGCACCAGCGCAATTCGTGGCGCACATGCGGCTGcacggcgcggcggcggcgcgcgcgcactgCGCCCCGTGCGGCGTCTCCTTCAAGGCGTGGCACGCCTACAACGCGCACGTGCTCTACAGCGCGCAGCACCAGCACCAGCGCAAGTTAGTGCTACTGTTCGTGTTGTGTACAGTTCGTGGCGCACATGCGGCTGcacggcgcggcggcggcgcgcgcgcactgCGCCCCGTGCGGCGTCTCCTTCAAGGCTTCGTGGCGCACATGCGGCTGcacggcgcggcggcggcgcgcgcgcactgCGCCCCGTGCGGCGTCTCCTTCAAGGCGTGGCACGCCTACAACGCGCACGTGCTCTACAGCGCGCAGCACCAGCACCAGCGCAAGTTAGTGCTACTGTTCGTGTTGTGTACAGTTCGTGGCGCACATGCGGCTGcacggcgcggcggcggcgcgcgcgcactgCGCCCCGTGCGGCGTCTCCTTCAAGGCTTCGTGGCGCACATGCGGCTGcacggcgcggcggcggcgcgcgcgcactgCGCCCCGTGCGGCGTCTCCTTCAAGGCGTGGCACGCCTACAACGCGCACGTGCTCTACAGCGCGCAGCACCAGCACCAGCGCAAGATAGCGTGCACCCACTGCGGCATGAAATTCGCGACGGCGACGCACCTCCGTATGCACGTGCAGTTCAGCGATCACCCGAAGGAGACCTTCCAGTGCCCAGACTGTCCCAAGgaATTTGCAGTGGAAGCTGAAATGAAACAGCACCGTAATATACATAAACAGCAGCGGCTGAAATCCACCGACAGGATATGTGACTACTGCGGTCGCGTTTATACTGTACCATCTCCGACGGGGTATCCTACCTTCGTCCCGCGAGCGGCTCTGACAATCCCCCGTGCCTTCCTTCATTTAGCTCCATCCACTATTCcagATGCTGGAATAGGAGTGTTCAGCACTTTGACGCTGCCTAAGGGAGTACGCTTCGGGCCCTACCGTGGGCTGAAGACGGATGGAGTGAACTCTTCTTACTGTTGGCAGATATACGACCACAATCGCAAACCATCCCACGTTCTAGACGCGCGCAACCCGAACAAGTCCAACTGGATGCGCTACGTCAACTGCTCCAGACACTTCAGCGAGCAAAACATGCTCGCTTTCCAGTACCAAGGACAGCTGACAATAAAAATAATCCCCCGCTTCACGGAGTTGCTGGTGTTCTATGGCAGCGAGTTCGCCAGCGAGCTGAATATAGACCTGCGGCGGTACCACTCGCCGGCCTACTCGGAGACACTTGGTAACGTATCATTCATAGATGGCGCCGCTTTCGCAATGTAA
Protein Sequence: MNGRVLDVVLASMDMSDTVCVRQVDPQEVLSKIDPHHPPIIARILYSFTSRAVGTNGTFQPENPTQFWSHVSSLRCKGGVEPKVTLGGVEYSGASAAAAFGTYFASVFLADRPILDPQVASACPPADARRVDIRRLSERDVRLAIKKLKPRASPGPDAVPAFVLKACVDNLVAPIKFIFNLILQTGVYPTAWKKSRVTPIPKKGSKLKIENYRPIAILSAIAKVFESALQSALLPQCLPNITSAQHAFLPKRSVVTNLLTLTRMVSQELDRKNQVDVIYLDFQKAFDRVDNDILLLKLGAMGFTPRLLKLFSSYLSDRKQFIKYGPYVSECYLTRSGVSQGSNLGPLLFVLLINDLLDEVRGSMVLLFADDVKLVKVIQSQSDCVDLQMDIDVVYRWSLRNKLYFNAEKCEMLTFTRSNTANDYQYNIGDVPIARVERVRDLGVIFDPGLTFRDHIQAVTKSASGRLGFVLRNSAPLTVHATRVLYTALVRSVLETNAVVWSPHESKYTLMLEQVQKMYLRALYKRIHFYYPYMYPTLFLQGQLGYDSLQLRRLIALAKFSIDVVRGKIDCVDLVEAFVRLCVPSWYIRARKHPLFAVPGSRTQAHAHKSHNPITRALAFLNSVHEAHPQCDLFASSTGRLMIECRKAEPAKKVVCLECHNVLKRIETFRQQVLKSFQSLTEQVPSLTPQNSDQSKKKTNLTHKKTVNIYLPPAKATPLTEKWQPTPPPQISKENVKKEESMEPALPVVKIKAEPLDSERETIEIEIVPVKKQEEVKARPDKTTNVAVRTVTLTKEELVLERLKLAQSAAYLKLPYRCESCVVGFNYEENIRDHMKRKHGPKVGSVTCDVCLAVLHPPGSLAAHMFRHLTRYECVKCDARYGNYDDALYHYKKQHGEPCLRCSECHYTTDSPQKFRKHKRQHHKRFTCKDCGVVLATRPSLTRHMAVLHNKRLYRCVHCSVTYTDGAAFVAHMRLHGAAAARAHCAPCGVSFKAWHAYNAHVLYSAQHQHQRKLVLLFVLCTVRGAHAAARRGGGARALRPVRRLLQGVARLQRARALQRAAPAPAQFVAHMRLHGAAAARAHCAPCGVSFKAWHAYNAHVLYSAQHQHQRKLVLLFVLCTVRGAHAAARRGGGARALRPVRRLLQGFVAHMRLHGAAAARAHCAPCGVSFKAWHAYNAHVLYSAQHQHQRKLVLLFVLCTVRGAHAAARRGGGARALRPVRRLLQGFVAHMRLHGAAAARAHCAPCGVSFKAWHAYNAHVLYSAQHQHQRKIACTHCGMKFATATHLRMHVQFSDHPKETFQCPDCPKEFAVEAEMKQHRNIHKQQRLKSTDRICDYCGRVYTVPSPTGYPTFVPRAALTIPRAFLHLAPSTIPDAGIGVFSTLTLPKGVRFGPYRGLKTDGVNSSYCWQIYDHNRKPSHVLDARNPNKSNWMRYVNCSRHFSEQNMLAFQYQGQLTIKIIPRFTELLVFYGSEFASELNIDLRRYHSPAYSETLGNVSFIDGAAFAM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -