Lstr040163.1
Basic Information
- Insect
- Lathronympha strigana
- Gene Symbol
- Znf131
- Assembly
- GCA_949128165.1
- Location
- OX421927.1:7706145-7718964[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.00026 0.023 16.4 0.5 2 23 303 325 302 325 0.97 2 11 0.038 3.4 9.6 3.2 2 23 333 355 333 355 0.95 3 11 0.0015 0.14 14.0 4.7 2 23 387 409 386 409 0.97 4 11 0.00018 0.015 17.0 0.8 2 23 418 440 418 440 0.94 5 11 0.59 52 5.9 1.8 3 21 453 471 451 472 0.92 6 11 0.096 8.4 8.3 0.1 3 23 485 506 483 506 0.91 7 11 0.0016 0.14 13.9 0.3 1 23 511 534 511 534 0.96 8 11 0.0032 0.28 13.0 1.0 3 23 568 588 567 588 0.97 9 11 4.3e-05 0.0038 18.9 0.1 1 23 594 617 594 617 0.95 10 11 0.00094 0.082 14.7 0.8 1 23 623 645 623 645 0.97 11 11 3.2e-05 0.0028 19.3 1.2 1 23 651 674 651 674 0.95
Sequence Information
- Coding Sequence
- ATGGATAGTGTGAAATTGGAATTAGAGCCGGAGAGTTTGGTAGCGTGTCGTATTTGCCTTGCTTGGGAGGGCAAGTTGTTTAACATTAGGGAATGGGGTCTTGACCAGCTGTACAGCGAAGTTACAGGCACTAGTttgtcaGCATGGGATGGGCTACCCCAGCACTTGTGCACATGGTGCCGAGCGCAGCTCGTAAAAGCGCATGCGCTGCGCATACGCAGCCACCGCGCCGATGCGCTGCTAAAGCAGGCTCTCATACATCAACACTTTATCTCGAACAACTATATCCGAACTATTGATAGAACAgcatataaattaattcatcCTTATTTTACTCACCTTAcgaaagaaacaataaatatcgtttttgatgaaaataaacaaacagaaagcaATGATGTGAAAGATGAACTAGAACGTGACATGATTGTTGGTGATGATCATCATCATGCTGATGATTTGgatgatgatttatttttgcCGAATGCTTTGAAACCGATTGATATTAACTTTGCTGATGTAACACTAGTTAAGGATGATGACTTGACAGAAATTAGTCCAGATAAGAGTGAAATTGTAGTTGAAGTAGGTATAGTACCGGCTAAAAAAATTGCTAAGAAACCGGCTAAAAGAAAAAAGGCAGTGGAAGAAATTATCGAAGAATCTCCAAAAAGAAGAAGATCTCAAAAGAGAAAAACGGAAGAGATAGAAGAGAAAGAAGCATCAGTTAAATTTGTAGTTAAAAAGAAAGAGAAACGTTTAAAGAAGAGTAAGATTAAGAGGGAAGAAGATTATAAAGAGTTTGAGAAGAAATATGACTTCCAGGTGAAGTGTTTGACGGAGGAAGAGATGGTGGAAGATATGGAGAGGAGGAAACTGTCGGACAAGGCCATTAAAGGTGTGGTGAAGTGCCAATTGTGTTATAAGGGGTTCATGAATAATACTACTTTGGAGAATCATATGAAGATTGCGCATGATCCGtcaGTGGGCTCGAATGAGTGTCACCTGTGTCACTCACGCTATCGGTTCGCAGTGAACCTCCGGCAGCATCTACAGAATGCGCACCAACTCATGTTCAAATGTAACCAGTGCGGGGACATCGTGTGGGGCGAATCGCATGCTGTTTTACACGCCGGTATCCACGCCGGGACAACGCTCAAGTGCCGGCATTGCGACAAACAATTCGTAAAGAAAACTACGCGAACGACGCATATGCGTATGGCGCATCCTGTGGAAAATGCAGCCGGCGGCACCTGCGAGGTCTGCGGGGAGACTTTCACTTCCCGCCGCGGGCTCCGGAGCCACAAGGCGCGGACACACAACAAGCAACTGCAGCCATCAGTGCCGGGGCTGTTCTGCCGCAAGTGCCGCGTGCAGTTCGACTCCAAGCAGGCGCTGCAGCACCACAAGCAACAGCAGGAGGGTCAGCGCTGCCACAACGACCACAGTGCGTGCGAGCAGTGCGGCGCGCTTTATCCGACCGAAGACGAATTGATCCGGCACAAGCACGAAGCGCACGGCGTCCAACTCTTCACGTGCGACGGGTGTTCCAAATCGTTCCTATCCAAGGTGTCTCTCTCTGTGCACATTGACCGCGTCCACTTGAACATAAAGCCGGTGCGTCCTAATCGTCCCAAGCCGGCCGGGGACCGCAGGGGACAGAAGTCGAAGCCGAAACAGAAGTTCAAGCTGGAAAACATGTGTGAGATCTGCGGGAAGGCTTATTCTTGTCTGGCGCTTCTGAAGACGCACCAAATGCGTCACACGGGAGACCGTCCCTTTAAATGCACGGAGTGCCCCAAAGGGTTCGTCACCGCCACGCTGCTGCGGGAGCACCGCGATATTGTGCACGCGCGCCTGCGCAAGTACCGCTGCCCGGAGTGCCCCAAGACCTTCCTGCACCAGTCCTCCGTCTACGTGCACCGAGCCATCCACACCGGCGAGAAGGCGTATGAATGCAGTTTCTGCGGCAAAGCGTTTACGCAGGCCGGCACGCTGCACACGCACGTCAAGTTCGTGCACATGAAGGTCAAGCCGCCGCCGCGCAAGCGCAACAAGAACATGATGGACGTCTAA
- Protein Sequence
- MDSVKLELEPESLVACRICLAWEGKLFNIREWGLDQLYSEVTGTSLSAWDGLPQHLCTWCRAQLVKAHALRIRSHRADALLKQALIHQHFISNNYIRTIDRTAYKLIHPYFTHLTKETINIVFDENKQTESNDVKDELERDMIVGDDHHHADDLDDDLFLPNALKPIDINFADVTLVKDDDLTEISPDKSEIVVEVGIVPAKKIAKKPAKRKKAVEEIIEESPKRRRSQKRKTEEIEEKEASVKFVVKKKEKRLKKSKIKREEDYKEFEKKYDFQVKCLTEEEMVEDMERRKLSDKAIKGVVKCQLCYKGFMNNTTLENHMKIAHDPSVGSNECHLCHSRYRFAVNLRQHLQNAHQLMFKCNQCGDIVWGESHAVLHAGIHAGTTLKCRHCDKQFVKKTTRTTHMRMAHPVENAAGGTCEVCGETFTSRRGLRSHKARTHNKQLQPSVPGLFCRKCRVQFDSKQALQHHKQQQEGQRCHNDHSACEQCGALYPTEDELIRHKHEAHGVQLFTCDGCSKSFLSKVSLSVHIDRVHLNIKPVRPNRPKPAGDRRGQKSKPKQKFKLENMCEICGKAYSCLALLKTHQMRHTGDRPFKCTECPKGFVTATLLREHRDIVHARLRKYRCPECPKTFLHQSSVYVHRAIHTGEKAYECSFCGKAFTQAGTLHTHVKFVHMKVKPPPRKRNKNMMDV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00654622;
- 90% Identity
- -
- 80% Identity
- -