Lstr040256.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Lathronympha strigana
Gene Symbol
-
Assembly
GCA_949128165.1
Location
OX421927.1:8256809-8258020[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.00028 0.025 16.3 2.3 1 23 51 74 51 74 0.95
2 10 5.1e-05 0.0045 18.6 3.0 2 23 82 104 81 104 0.94
3 10 0.11 10 8.1 5.2 2 23 112 134 111 134 0.95
4 10 7.7e-05 0.0067 18.1 3.1 2 23 142 164 141 164 0.96
5 10 0.00023 0.02 16.6 4.2 1 23 171 194 171 194 0.93
6 10 0.0016 0.14 13.9 5.8 1 23 200 223 200 223 0.94
7 10 1.1e-05 0.00099 20.7 0.3 2 23 231 252 230 252 0.97
8 10 0.0052 0.45 12.3 2.0 2 23 260 282 259 282 0.96
9 10 0.00024 0.022 16.5 3.4 2 23 289 311 288 311 0.94
10 10 0.00019 0.017 16.8 3.7 1 23 321 343 321 343 0.98

Sequence Information

Coding Sequence
ATGGACCCGAAACCAGAGCCAGCGCCTCCGCCCAAGGACATGAAGTTCATCTCTGTTACCAGCGACGTACTGACAGACGAGCAACGAGAGATGTACGAGTCTGTCCTCACTACGTGGAAACCAGTACTCTTCCCCAAGCGAGCAAAACGCTACATCTGCCAGAAATGCAATAAGGAATTCAAAAACTACCAAAATCTTTATTTACACACAACCAGGGTACACTCTTCAGAAGAATCCGCCGTTATGTGCGATATATgtgataaaacatttaaaaacaagcACTATTTATACATGCATAGGATGAACAAACATTATTCGGAAGAGGAGAAATGCTTCTGCCAATATTGCTTGCAAGAGTTTAGGACGAGGCGCGCTCTGCATATGCATGTGAAGAGGATTCATCCGGCTACGTTACCGGAGATAAAGTGCCATGAGTGTGGAAAAGAATTCAACGTACCGTACAAGTTGAAATATCATATAGAGCGATGTCATAGGCTCGATAAGGACAAATACAAATGTCCTATCTGTGAAAAGATATACAAAAGCCATTTAAACTTAAACAGACATTTGCACTTCCAGCATTCGCAAGTTGAAAGACATCCGTGCGTTTTCTGCGATATGACTTTTAAATCGCGTCACCATATGAAAcgacatattttaaatatacacCCGCCTTTAGAGTCCAAAGTGCAATGTCCAGAGTGCTCAAAAGAGTTCAAAAACGATCAGTACTTAAAAGAGCACATGCAAGTTCATTCCTCTTTAGACACTAAAGTAAAATGCGATCTCTGTGATAAATACTTTCATTCAGCGATCCGTTTAAAGAAGCATAAAAAGATAGTACATCCGGATAAGCCTAAAATACGTTGCGAGAAGTGTGATAAAGAATTCGCCCATGAACATTATTTGCGTCGCCATAACAATTCAGTCCACGTTGAGTTAAAAGAGTCGGATTATCAACATGAATGCAAACAGTGTGGGAAGAAGTTTAAAATTGGAAGATATCTTAATAACCACATGCAGAGACACGAACAGCAGCATTTGAAAAGGATATCGATGATGGTGAAGACGGTTTTGGATGATGGGACGCCGGTGAGGAAGAAGAGAGGTAGGAAGCCGAGGGAACCACCGAAAGAGATAGAGTTTATTAAATGCGAGCCGGTGTCTAGTTCGGAGTCTTCTGGTGATAGCGATGAAACGGACTCAGAGTAA
Protein Sequence
MDPKPEPAPPPKDMKFISVTSDVLTDEQREMYESVLTTWKPVLFPKRAKRYICQKCNKEFKNYQNLYLHTTRVHSSEESAVMCDICDKTFKNKHYLYMHRMNKHYSEEEKCFCQYCLQEFRTRRALHMHVKRIHPATLPEIKCHECGKEFNVPYKLKYHIERCHRLDKDKYKCPICEKIYKSHLNLNRHLHFQHSQVERHPCVFCDMTFKSRHHMKRHILNIHPPLESKVQCPECSKEFKNDQYLKEHMQVHSSLDTKVKCDLCDKYFHSAIRLKKHKKIVHPDKPKIRCEKCDKEFAHEHYLRRHNNSVHVELKESDYQHECKQCGKKFKIGRYLNNHMQRHEQQHLKRISMMVKTVLDDGTPVRKKRGRKPREPPKEIEFIKCEPVSSSESSGDSDETDSE