Lstr040358.1
Basic Information
- Insect
- Lathronympha strigana
- Gene Symbol
- zfh1
- Assembly
- GCA_949128165.1
- Location
- OX421927.1:8964445-8980202[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.00021 0.019 16.7 0.3 1 23 305 327 305 327 0.98 2 12 0.2 17 7.4 1.7 1 23 334 356 334 356 0.90 3 12 1.9 1.7e+02 4.2 6.1 1 23 360 382 360 382 0.96 4 12 6.7e-06 0.00059 21.4 2.4 1 23 387 410 387 410 0.96 5 12 0.0017 0.15 13.8 0.2 3 23 417 438 416 438 0.97 6 12 0.0069 0.61 11.9 0.1 1 20 447 466 447 472 0.93 7 12 0.003 0.27 13.1 0.1 3 23 478 499 477 499 0.93 8 12 0.025 2.2 10.2 1.8 1 23 504 527 504 527 0.95 9 12 0.0012 0.11 14.3 0.5 1 23 550 572 550 572 0.97 10 12 1.6e-05 0.0014 20.2 1.4 1 23 578 600 578 600 0.96 11 12 1.3e-05 0.0011 20.5 1.6 1 23 606 629 606 629 0.95 12 12 3.6e-06 0.00031 22.3 0.9 2 23 637 659 636 660 0.96
Sequence Information
- Coding Sequence
- ATGGATATAATACATGATTTGTCGTCAAACCACGATGCTCTGTTGTGCTGCCGTGCTTGTTTGGCGACCGACGCGAGGTTGTTCAATATCCATGAATACAGACTTGCAGATGCCTTCAATCGCATCTCTGGGACTCCTGTGTTCAGAGATGGGCCGCAGCACCTGTGCAGCTATTGCAGCACGCAGCTGCTGCGCTGCGAGTCGTTCCGTGCCAAGTGCATGCGAGCGCAGCAGTGTCTCAGCTCGAAGAATCACCAAGGAGAGTTGGATACAGACTACATTCGCACCATAGACCGCTCGTCCCTCAAGTTGCTCCTGAACTTGACCGCAGACCCGGTGCAGACCCTCGAGTGCGTCGACCCTATACCGGTCGAAGACATCAAGAACGAGCCTAATATTGACATCACTGACGACGTAGACGCTGTAGACAGCaagaaaaccgacttcaaaatagaAGTAGAGCTCGACGAAGACAAACTAGAACAAGTATTCGTCGTGACCGACATAGAAGATgtcaaaaaaagaaagaaaaaatccGGAAATACGCCTAGAAAAAAGATAAAACGCGAATCAGACGATCATTTTGATGACGTAGGAGACATTCATGATGACGACGATGATGATATCAGCTTAGATAATGTTGCAAAGAGTCTAGTTAAAAAAAGGAAAGTCAAGGCTAAAAAGGTTGTTAAGAAGAAAGAGGAAAAGCCAGTGAAAATTAAGGTTGTTAAACAGAAACCGGTGAGAGAGTTGAAGATAAAGAGGAGGAACCCTGCCAATGGGTATTTGCCGGAGTTTGCGATGGCGGCCTTCGAGAACATGTATTCTGTACATGTTGTCACTTTAAGCAAGGAGGACCAAATGGAAGAGATCGCAATGCGGAAAGAGTCCGCCAACTACCAGGAGTCCGCGTTCCAATGCGAGGACTGCGGGAAGGGCTTCGTCGCCGAAGAGTCGTACAACAACCATCGCACGAGGCACAGCCCGAGCGCAGGTAATTTCCCCTGCGAGATATGTAACGTGCGCTTCACGAAGCAAAGTATACGACACACGCACCAAGACATGcaccggctgaagttcttctgTAAGGAGTGCAGCTTCGTATCCAGAACCAGGCACCAGGCGAAGCAGCATCATGAAATGCACGTTGGCAAGACATTCGAGTGTCAACATTGCGGGAAGAGTTTCAGTAAAAGCTCTACGTACCTGTCGCACGTGCGGCTCGCGCACCCGGCGCTCAATGTGGCGTGCGACGAGTGCGGCGAGACCTTCGTCGGACAGATGGGGCTGAAAATGCACAAGAAGCGGATGCACGCCAAGAGCGTGAAACCCGAACAGTTCAAATGCACGACTTGTTCGGCAACCTTCATCAGTGTGGAGGCGCTGAACCGACACGCGGACACGGCGGGCGAGCACAGCGACCTGCGGCCGTGCGAGCAGTGCGGCGAGAACTGTGCGAGCGAGGAAGCACTAGAGAAACATATGGAAGAGATGCATCCGAAAGAATCACATCGGTGTGAAGAGTGTAATGCGACGTTCGCAAGTTCAGCGGCGTACGACCTCCACCATCTCCGCAAACACCTGAACCAGCCGTTCAGCGCAGCGGGCCGCAGGACCCTGCACAGGGAGCCCCTGGTGCCGGGCCAGTTCGTGTGCGAGCAGTGCGGACGGATACTGCCGACGCGGACGTCCCTGCGCTACCACAAGCGGGACCACAAGACGGCGAAGCCCCACGCGTGCCGCCAGTGTCCCAAAAGCTTCTCCACCAAACGAGCGCTCGATTGGCATATCCGTTCGCACACCGGTGAGAAACCGCACCAGTGTCCCGAGTGTCCGCTCGCCTTCAGCATCAAGTCAAACCTGAAGAGACACCACAAGGCTGTGCACCTTGGGCTCCGGAACAGCGTTCCCTGCCCCATCTGTGGACGTGTATTCACAACCAACTCCTGCGTCCGCATACACATCAACACGGTGCACCACGGACAGCCAGGGCCCAAGCGGAACAGGAAACGGGCTAAATACGGGAAGAATGTTCCCGAGTCGCCCGCCAGTCttatttag
- Protein Sequence
- MDIIHDLSSNHDALLCCRACLATDARLFNIHEYRLADAFNRISGTPVFRDGPQHLCSYCSTQLLRCESFRAKCMRAQQCLSSKNHQGELDTDYIRTIDRSSLKLLLNLTADPVQTLECVDPIPVEDIKNEPNIDITDDVDAVDSKKTDFKIEVELDEDKLEQVFVVTDIEDVKKRKKKSGNTPRKKIKRESDDHFDDVGDIHDDDDDDISLDNVAKSLVKKRKVKAKKVVKKKEEKPVKIKVVKQKPVRELKIKRRNPANGYLPEFAMAAFENMYSVHVVTLSKEDQMEEIAMRKESANYQESAFQCEDCGKGFVAEESYNNHRTRHSPSAGNFPCEICNVRFTKQSIRHTHQDMHRLKFFCKECSFVSRTRHQAKQHHEMHVGKTFECQHCGKSFSKSSTYLSHVRLAHPALNVACDECGETFVGQMGLKMHKKRMHAKSVKPEQFKCTTCSATFISVEALNRHADTAGEHSDLRPCEQCGENCASEEALEKHMEEMHPKESHRCEECNATFASSAAYDLHHLRKHLNQPFSAAGRRTLHREPLVPGQFVCEQCGRILPTRTSLRYHKRDHKTAKPHACRQCPKSFSTKRALDWHIRSHTGEKPHQCPECPLAFSIKSNLKRHHKAVHLGLRNSVPCPICGRVFTTNSCVRIHINTVHHGQPGPKRNRKRAKYGKNVPESPASLI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01134205;
- 90% Identity
- -
- 80% Identity
- -