Basic Information

Insect: Lathronympha strigana
Gene Symbol: Bcl11b
Assembly: GCA_949128165.1
Location: OX421925.1:6013536-6021112[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.34 30 6.6 4.1 1 23 138 163 138 163 0.69

2 12 1.4e-05 0.0012 20.4 2.5 1 23 169 191 169 191 0.94

3 12 0.00083 0.073 14.8 1.9 1 23 197 219 197 219 0.98

4 12 4.2e-07 3.7e-05 25.2 2.3 1 23 225 247 225 247 0.99

5 12 3.5e-05 0.0031 19.2 0.2 3 23 259 279 257 279 0.97

6 12 6.4e-05 0.0056 18.3 0.6 1 23 297 319 297 319 0.97

7 12 5.7e-06 0.0005 21.7 2.7 1 23 325 347 325 347 0.99

8 12 1.1e-05 0.001 20.7 4.1 1 23 353 375 353 375 0.96

9 12 0.00031 0.027 16.2 0.5 1 23 381 403 381 403 0.98

10 12 0.00013 0.012 17.3 2.4 1 23 409 432 409 432 0.96

11 12 0.00039 0.034 15.9 0.3 1 23 438 460 438 460 0.98

12 12 0.00011 0.0096 17.6 0.3 1 23 466 489 466 489 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.34	30	6.6	4.1	1	23	138	163	138	163	0.69
2	12	1.4e-05	0.0012	20.4	2.5	1	23	169	191	169	191	0.94
3	12	0.00083	0.073	14.8	1.9	1	23	197	219	197	219	0.98
4	12	4.2e-07	3.7e-05	25.2	2.3	1	23	225	247	225	247	0.99
5	12	3.5e-05	0.0031	19.2	0.2	3	23	259	279	257	279	0.97
6	12	6.4e-05	0.0056	18.3	0.6	1	23	297	319	297	319	0.97
7	12	5.7e-06	0.0005	21.7	2.7	1	23	325	347	325	347	0.99
8	12	1.1e-05	0.001	20.7	4.1	1	23	353	375	353	375	0.96
9	12	0.00031	0.027	16.2	0.5	1	23	381	403	381	403	0.98
10	12	0.00013	0.012	17.3	2.4	1	23	409	432	409	432	0.96
11	12	0.00039	0.034	15.9	0.3	1	23	438	460	438	460	0.98
12	12	0.00011	0.0096	17.6	0.3	1	23	466	489	466	489	0.97

Sequence Information

Coding Sequence: ATGGGGAATGACGAGTGTGGGATATGCGAGGTGTGCGTGGGGCAGCTGCGGCAAGCGTGTGACTTCAAGAAGCAAGTGCAGCGCAGCCAGGCCGAGCTGCACGCGCGGCTCAAGGGTGTGCTCACTGCCAGTGACAATCTCAAAATCAAATTGGAAAAAGCCAATGCGGATGAAAGCATCACACGCGATATAAAGGTGGAGAAGTCCGACTTTGAGATGGCTGATGGCGAGATCGTATCGGTGGCCATACACGAAGGCCCGCCAGCGCCTTCCGCAAAACCTGTTTCTACTGTATCCGAGAGCATCGCTTCTGTGCCTGATCCCGCACCGCCGCCGCAGACGCTCACCGATCTGGATGAAACCGGCCAGCAACCCGATGAGACGGCTTCCACTTCAAGTGGCGCTAATGCCCACACATGTGATATTTGCCACAGGACGTTCGACAATCCAAATGCTAAATCTAAACTCGTGATCCACCGCCGCATACACACAGGAGAGAAACCATACGCGTGCAGCGTATGCGACAAAAAATTCGCACAAAAAAGTCACTTAAATACTCATTTCGCATACCACCTGGGGAAATTCAAATTCTCCTGCGAATTTTGTGACAAACGATTCCTACAAAGAAATCAATTTGTCGTCCACATGCGGCTACATACTGGTGAAAAACCGTACTCGTGTGATATGTGCAACAAAAAatacagacaacaaagtgactTAAATGTTCATAGAAGAACTCACATCGAATACGATCCTGTGAAACAACCGTTCGGCTGTGATTTATGCGGAAAACGATTTGCACTGCAGGGGAATTTAGTTAAACATATGGAACAACACGCTCAAAAAGAAAAGGACCAAAAAGAAGGAAAAACAGAAGATCCAAAGCCCTTTGAGTGTGAAATATGTAACAAACGATTTTCCTCAAAGGGTATCTTAAGAAATCATAGAGAAATACATACCGAAGATACACCTTTCCAATGTGATGTATGTCATAAGAAGTTCAGAGTAAAAAAGTATTTAGAAGTGCACATAAAAGTCCATGAGAACACCAAACAACATGCTTGTGAAGTGTGCGGTCAACAGTTTACACACAGATCAAGTTTTAAACGTCATATCAAAATACATACTGGCGAAAAGAAATTTTCCTGCGAAGTTTGTAATAAGCGATTCGGACGCTCAACAATTTTGCGAGACCACATGCTCATACATAGCGGTCTGAAACTGCACAATTGTAAAGTGTGTAATAAGCAATTTAGACAGAAAAATGCTTTAGACGTCCACGTGCGACGACTTCACACAGGCGAACGGCCTTATCCCTGTGAAGTGTGTAAGAAAGCATTTGCTGAGTTGTCCGCTTTAAAGTTCCATTATCGAACGCATACTGGAGAGAAACcttatgtttgtgaaatatgtCATATGAAATTTGTTCGACCTGAAGGTGTCAGGAAACATCTCATTCGTGTTCATAAGGAGAAACCTTCGAAATTTgtggtaattaaataa
Protein Sequence: MGNDECGICEVCVGQLRQACDFKKQVQRSQAELHARLKGVLTASDNLKIKLEKANADESITRDIKVEKSDFEMADGEIVSVAIHEGPPAPSAKPVSTVSESIASVPDPAPPPQTLTDLDETGQQPDETASTSSGANAHTCDICHRTFDNPNAKSKLVIHRRIHTGEKPYACSVCDKKFAQKSHLNTHFAYHLGKFKFSCEFCDKRFLQRNQFVVHMRLHTGEKPYSCDMCNKKYRQQSDLNVHRRTHIEYDPVKQPFGCDLCGKRFALQGNLVKHMEQHAQKEKDQKEGKTEDPKPFECEICNKRFSSKGILRNHREIHTEDTPFQCDVCHKKFRVKKYLEVHIKVHENTKQHACEVCGQQFTHRSSFKRHIKIHTGEKKFSCEVCNKRFGRSTILRDHMLIHSGLKLHNCKVCNKQFRQKNALDVHVRRLHTGERPYPCEVCKKAFAELSALKFHYRTHTGEKPYVCEICHMKFVRPEGVRKHLIRVHKEKPSKFVVIK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -