Lstr040248.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Lathronympha strigana
Gene Symbol
ZEB2
Assembly
GCA_949128165.1
Location
OX421927.1:8162439-8180258[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.013 1.1 11.1 4.4 1 23 230 252 230 252 0.98
2 16 0.0017 0.15 13.9 2.6 2 23 260 281 259 281 0.96
3 16 0.21 19 7.2 1.9 1 23 285 308 285 308 0.96
4 16 0.0012 0.11 14.3 0.3 1 23 313 336 313 336 0.96
5 16 0.16 14 7.6 5.9 1 23 339 362 339 362 0.93
6 16 0.38 33 6.5 0.0 2 19 376 393 375 395 0.93
7 16 0.055 4.8 9.1 0.1 3 23 407 427 405 427 0.94
8 16 0.00021 0.018 16.7 1.2 2 23 434 456 433 456 0.95
9 16 0.0002 0.018 16.8 0.2 2 23 474 496 473 496 0.95
10 16 1.5e-05 0.0013 20.4 4.0 1 23 505 527 505 527 0.98
11 16 4.6e-05 0.004 18.8 0.3 1 23 533 555 533 555 0.99
12 16 0.0006 0.053 15.3 0.5 1 23 561 584 561 584 0.92
13 16 2.5e-06 0.00022 22.8 0.6 1 23 593 615 593 615 0.98
14 16 0.0006 0.053 15.3 0.4 1 21 621 641 621 642 0.94
15 16 0.00056 0.049 15.4 1.6 1 23 653 675 653 675 0.96
16 16 0.00059 0.052 15.3 0.7 1 23 681 704 681 704 0.96

Sequence Information

Coding Sequence
ATGGCGGAATTACTTGCGTGTCGTACATGTCTTATTACAGACGTTAAACTTTATGATATGTTCAAATATAAGTTAGCAGAACCGTTCGCACTTCTGACGCGAACagagGACTTAGGGCAGGGCCTACCCCAACATATGTGTGGCATATGTGCCTCTGTTCTGCTAAGAAGTGTAACATTCCAAATACAGTGTAACACAGCCATGCGTGTACTGCAGAAGGCTGTAACGCAAGAAACTGAGctGACAATGCAATTTGTAAGGTCCATAGACCGCTCGGTATACTCCTTTGGACCCGCACTAGCTTTCACACCAATAGAGCAAAACAACTATATACATGAGGCCAACATCgacgtaaaaaaatatacagaccAAGACACTTCAGATGAACTTATGGATATAGAGGTTCATAATATTAAACTAGATATAGAACAGGATGAAAACTTATCAGACAATGAAGTTGAAGCAAAACTAGAGAATTCTGATAGTGAAGATGTTTGCGTTTTATGTGATTACTTCGGAGTTGATAAGTGCGATGAAATGATGGAGGGTTTCCCAAATGAGACGGGGAATGAAATTAGTGATGACCAAAACGACAGTAATGATattaaagttattttgttggataaagaaCAACAGGTAGAAGAGTTGTTGAAGAATAAGGAGAGTGTACAATACTTGACGGCTAAATATAGGTGTGATAAGTGCTATAAGTCGTATAATATTGAGTATATGTACAGGGCGCATATGAAGCATCATGACCCGgaGAGTGGAGAGCTTGTGTGCGAGGTGTGCCGCCGGCGGTACAGTCAACGCCATGAGTTCAACAACCACGTGAAGTCCCACGAGCGGCGTTACCAGTGCCAGCAATGTCAGCACGTCAGCAAGGATCTATGGACAGCGAAGAAACACTTATCGGTGTTTCACGAAGAAGTGGAGTACGCGTGTGAGCCCTGCGGAGAATCGTTCACGGTCCACAACGCGTACGCGGCGCACATGCGGACGAAGCACGCGGAGCACCGCTGCGACCTGTGCGGAGACTGCTTCACCACGTTCAAGGGACTCCGCCACCACCGGGTCATCACACATCTCAACAAGgTCGAGGCCCTGAAACACTGCAAGGACAATGTATGTATGTCTTGCAACACCAACTTCGACAGTCCAGAGGCCCTGGAAGCACACAAGGGGGGTGAAAGTACTTGCAACACTGACATGAAaccgTGCGTCGCTTGTGGCGCGGGATTCGAAACAGAAAAAGAGTTGAAAGAACATAAGAAAATACATCGGAAAAAACCATCTGTTAAATGCCAGCTAtgCGACAAGATGTTCGCGGATCGCTACTCGTACAGAACTCACTATAAGGAGAACCACTTCAAGGGGACCCACAAACCAGACCAGCAGACCAAACCAAAGATGGCGTCCGTCTGTGAAGTCTGCGGCAAGATATGTCGGACGCCATTCGGGCTCCGTGCGCACCAGGCGCGCGCGCACTGCGGCGCCGCGCCCAAGCACAAGCATGTCTGCAACCAGTGTGGGCAAACCTTCGCTACTAGTAATCATTTGATGGTCCACTACAGGAAACACACGGGTGAGAGACCGTTCCAGTGCGAACGCTGCCCGAAAGCATTCTACACCAGACCAGCCCTGGTCACGCACACACGGATTCACACAGGAGAGAAACCCTTCTTGTGCGAGTTCTGCGGCAAGGCGTTCACTCAGTCCAAAACTCGGAAGATTCACATCATGGGCGTGCACAAGGACCTGGTCGGCGGCAAGCGGTTCCCCTGCAGCATGTGCCCCAAGACGTTCTCACTGGCTAGCTACCTCAAGGAGCACTTAAGGAGACACACTGGTGAGAAACCGTACAAGTGCGAAATATGCTCAAGACCATTCACGAGTCCGGGGGAACTCCATGGTCACAAGAAGAGGCGCACGAGAAATAACATCGGTGAGAAACCATACGAATGCAAAAGCTGTCCGAAAGCTTTTTTCAACAGTTCTTCGCTGTATACTCACAACAAGGAACACCGGGGTAAGAAGGCGTATTCGTGCCCGCACTGCGACCAGGTGTTCGGGTACTCGTTCACTATGAACGACCACATCGCCATGCAGCACCTCGGCACCAAGCCCAAGAGAGTCAAGAAGAAGACGAAACAGGAGGACACTGAAAACGCAAATGAAACTGAAACCGCCGGACTGAAATGCACCGATATAGAAGCGAGACCTAAAAAGCGGAGAGCTGAGAAGCCGAGTGAGGGCGAAGGAACAGAGTTCGAGCAGAGTTCCGATCTAGAGAGTGAACGCAGGTACTTATACGTCGAAGCCGAGGAGCGCCAATATCTGGTCGTGAGTAACGAAGAGGATGAATAG
Protein Sequence
MAELLACRTCLITDVKLYDMFKYKLAEPFALLTRTEDLGQGLPQHMCGICASVLLRSVTFQIQCNTAMRVLQKAVTQETELTMQFVRSIDRSVYSFGPALAFTPIEQNNYIHEANIDVKKYTDQDTSDELMDIEVHNIKLDIEQDENLSDNEVEAKLENSDSEDVCVLCDYFGVDKCDEMMEGFPNETGNEISDDQNDSNDIKVILLDKEQQVEELLKNKESVQYLTAKYRCDKCYKSYNIEYMYRAHMKHHDPESGELVCEVCRRRYSQRHEFNNHVKSHERRYQCQQCQHVSKDLWTAKKHLSVFHEEVEYACEPCGESFTVHNAYAAHMRTKHAEHRCDLCGDCFTTFKGLRHHRVITHLNKVEALKHCKDNVCMSCNTNFDSPEALEAHKGGESTCNTDMKPCVACGAGFETEKELKEHKKIHRKKPSVKCQLCDKMFADRYSYRTHYKENHFKGTHKPDQQTKPKMASVCEVCGKICRTPFGLRAHQARAHCGAAPKHKHVCNQCGQTFATSNHLMVHYRKHTGERPFQCERCPKAFYTRPALVTHTRIHTGEKPFLCEFCGKAFTQSKTRKIHIMGVHKDLVGGKRFPCSMCPKTFSLASYLKEHLRRHTGEKPYKCEICSRPFTSPGELHGHKKRRTRNNIGEKPYECKSCPKAFFNSSSLYTHNKEHRGKKAYSCPHCDQVFGYSFTMNDHIAMQHLGTKPKRVKKKTKQEDTENANETETAGLKCTDIEARPKKRRAEKPSEGEGTEFEQSSDLESERRYLYVEAEERQYLVVSNEEDE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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