Basic Information

Insect: Lathronympha strigana
Gene Symbol: Hr78_1
Assembly: GCA_949128165.1
Location: OX421922.1:11824001-11859229[-]

Transcription Factor Domain

TF Family: RXR-like
Domain: zf-C4|RXR-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers. Each zinc finger contains a group of four Cys residues which co-ordinates a single zinc atom. RXR functions as a DNA binding partner by forming heterodimers with other nuclear receptors including CAR, FXR, LXR, PPAR, PXR, RAR, TR, and VDR. All RXR heterodimers preferentially bind response elements composed of direct repeats of two AGGTCA sites with a 1-5 bp spacer. RXRs can play different roles in these heterodimers. RXR acts either as a structural component of the heterodimer complex, required for DNA binding but not acting as a receptor, or as both a structural and a functional component of the heterodimer, allowing 9-cis RA to signal through the corresponding heterodimer. In addition, RXR can also form homodimers, functioning as a receptor for 9-cis RA, independently of other nuclear receptors. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, RXR has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [cite:PUB00121610], [cite:PUB00121611], [cite:PUB00121612], [cite:PUB00025660], [cite:PUB00121613], [cite:PUB00092048], [cite:PUB00092725], [cite:PUB00092726], [cite:PUB00016724], [cite:PUB00059514PMID:18971932
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 34 0.6 3e+03 -0.9 0.0 1 27 258 284 258 287 0.93

2 34 0.6 3e+03 -0.9 0.0 1 27 293 319 293 322 0.93

3 34 0.6 3e+03 -0.9 0.0 1 27 328 354 328 357 0.93

4 34 0.6 3e+03 -0.9 0.0 1 27 363 389 363 392 0.93

5 34 0.6 3e+03 -0.9 0.0 1 27 398 424 398 427 0.93

6 34 0.6 3e+03 -0.9 0.0 1 27 433 459 433 462 0.93

7 34 0.6 3e+03 -0.9 0.0 1 27 468 494 468 497 0.93

8 34 0.6 3e+03 -0.9 0.0 1 27 503 529 503 532 0.93

9 34 0.6 3e+03 -0.9 0.0 1 27 538 564 538 567 0.93

10 34 0.6 3e+03 -0.9 0.0 1 27 573 599 573 602 0.93

11 34 0.38 1.9e+03 -0.2 0.0 1 28 608 635 608 642 0.90

12 34 0.6 3e+03 -0.9 0.0 1 27 643 669 643 672 0.93

13 34 0.6 3e+03 -0.9 0.0 1 27 678 704 678 707 0.93

14 34 0.6 3e+03 -0.9 0.0 1 27 713 739 713 742 0.93

15 34 0.6 3e+03 -0.9 0.0 1 27 748 774 748 777 0.93

16 34 0.6 3e+03 -0.9 0.0 1 27 783 809 783 812 0.93

17 34 0.6 3e+03 -0.9 0.0 1 27 818 844 818 847 0.93

18 34 0.6 3e+03 -0.9 0.0 1 27 853 879 853 882 0.93

19 34 0.6 3e+03 -0.9 0.0 1 27 888 914 888 917 0.93

20 34 0.6 3e+03 -0.9 0.0 1 27 923 949 923 952 0.93

21 34 0.6 3e+03 -0.9 0.0 1 27 958 984 958 987 0.93

22 34 0.6 3e+03 -0.9 0.0 1 27 993 1019 993 1022 0.93

23 34 0.6 3e+03 -0.9 0.0 1 27 1028 1054 1028 1057 0.93

24 34 0.6 3e+03 -0.9 0.0 1 27 1063 1089 1063 1092 0.93

25 34 0.6 3e+03 -0.9 0.0 1 27 1098 1124 1098 1127 0.93

26 34 0.6 3e+03 -0.9 0.0 1 27 1133 1159 1133 1162 0.93

27 34 0.6 3e+03 -0.9 0.0 1 27 1168 1194 1168 1197 0.93

28 34 0.6 3e+03 -0.9 0.0 1 27 1203 1229 1203 1232 0.93

29 34 0.6 3e+03 -0.9 0.0 1 27 1238 1264 1238 1267 0.93

30 34 0.6 3e+03 -0.9 0.0 1 27 1273 1299 1273 1302 0.93

31 34 0.6 3e+03 -0.9 0.0 1 27 1308 1334 1308 1337 0.93

32 34 0.6 3e+03 -0.9 0.0 1 27 1343 1369 1343 1372 0.93

33 34 0.65 3.3e+03 -1.0 0.0 1 27 1378 1404 1378 1406 0.93

34 34 8.3e-30 4.2e-26 93.3 0.1 1 196 1413 1622 1413 1624 0.85

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	34	0.6	3e+03	-0.9	0.0	1	27	258	284	258	287	0.93
2	34	0.6	3e+03	-0.9	0.0	1	27	293	319	293	322	0.93
3	34	0.6	3e+03	-0.9	0.0	1	27	328	354	328	357	0.93
4	34	0.6	3e+03	-0.9	0.0	1	27	363	389	363	392	0.93
5	34	0.6	3e+03	-0.9	0.0	1	27	398	424	398	427	0.93
6	34	0.6	3e+03	-0.9	0.0	1	27	433	459	433	462	0.93
7	34	0.6	3e+03	-0.9	0.0	1	27	468	494	468	497	0.93
8	34	0.6	3e+03	-0.9	0.0	1	27	503	529	503	532	0.93
9	34	0.6	3e+03	-0.9	0.0	1	27	538	564	538	567	0.93
10	34	0.6	3e+03	-0.9	0.0	1	27	573	599	573	602	0.93
11	34	0.38	1.9e+03	-0.2	0.0	1	28	608	635	608	642	0.90
12	34	0.6	3e+03	-0.9	0.0	1	27	643	669	643	672	0.93
13	34	0.6	3e+03	-0.9	0.0	1	27	678	704	678	707	0.93
14	34	0.6	3e+03	-0.9	0.0	1	27	713	739	713	742	0.93
15	34	0.6	3e+03	-0.9	0.0	1	27	748	774	748	777	0.93
16	34	0.6	3e+03	-0.9	0.0	1	27	783	809	783	812	0.93
17	34	0.6	3e+03	-0.9	0.0	1	27	818	844	818	847	0.93
18	34	0.6	3e+03	-0.9	0.0	1	27	853	879	853	882	0.93
19	34	0.6	3e+03	-0.9	0.0	1	27	888	914	888	917	0.93
20	34	0.6	3e+03	-0.9	0.0	1	27	923	949	923	952	0.93
21	34	0.6	3e+03	-0.9	0.0	1	27	958	984	958	987	0.93
22	34	0.6	3e+03	-0.9	0.0	1	27	993	1019	993	1022	0.93
23	34	0.6	3e+03	-0.9	0.0	1	27	1028	1054	1028	1057	0.93
24	34	0.6	3e+03	-0.9	0.0	1	27	1063	1089	1063	1092	0.93
25	34	0.6	3e+03	-0.9	0.0	1	27	1098	1124	1098	1127	0.93
26	34	0.6	3e+03	-0.9	0.0	1	27	1133	1159	1133	1162	0.93
27	34	0.6	3e+03	-0.9	0.0	1	27	1168	1194	1168	1197	0.93
28	34	0.6	3e+03	-0.9	0.0	1	27	1203	1229	1203	1232	0.93
29	34	0.6	3e+03	-0.9	0.0	1	27	1238	1264	1238	1267	0.93
30	34	0.6	3e+03	-0.9	0.0	1	27	1273	1299	1273	1302	0.93
31	34	0.6	3e+03	-0.9	0.0	1	27	1308	1334	1308	1337	0.93
32	34	0.6	3e+03	-0.9	0.0	1	27	1343	1369	1343	1372	0.93
33	34	0.65	3.3e+03	-1.0	0.0	1	27	1378	1404	1378	1406	0.93
34	34	8.3e-30	4.2e-26	93.3	0.1	1	196	1413	1622	1413	1624	0.85

Sequence Information

Coding Sequence: ATGGATGGCCAGGACCAGATGGAGATGAAATTCAGCGGAGGCAGCGAAGTCGGCGGGATGGAGCTCTGCATTGTGTGCGGAGACCGAGCATCTGGGAGACACTATGGCGCTATCAGCTGTGAAGGTTGCAAAGGCTTCTTCAAACGCAGCATCCGCAAGAAGCTCGGCTACCAATGTCGGGGCAGCATGAACTGCGAGGTGACCAAGCACCACCGTAACAGGTGCCAGTACTGCCGGTTGCAGAAGTGTTTGGCCTGCGGCATGAGGAGCGACTCGGTCCAGCACGAACGGAAGCCGATCGTGGACAAAGTGAAACCCGAGCGGGGAGAGGGTCTTCACGAGCGGCAGGCGTATTCTAAGCTGTTGGGATTGGCTGGCCAGCAGGGACCGATAAATCCGAAGGAGGAGCCGGGAGAGTtcggcgcggcgccggcgcccgccaTCAACTTCGCGCTGGCCGCCGCCGTCGCCTTCAACAAGGGCAACCCAGTGCCGGGGTACCTGGGCGCCGGCGACGTGGAGGGCGCGCGGCGCCAGCAGCTGCTGCTGCAGACGCAGCTCGCCAAGAACCTCTTCAAGATGGGGCAGTTCGGAGCCATCAACGAGTACCTGCAGTCGGCGTACGCGGCCCCGGAGGCGCCGCAACTGCCGCAAGCCGACGCTCCACAGCCAGAAGTAGCGGACCCGTCGGCCGTCCTGTGCACGGCGGAGTCGCTGGCGCTGCAGCTGGCGCTGCCGGCGGGCGCGCCGCCGCACCTGCGCCTGCACGCCGtgtgcgaggcgggcgcgcgcctgctggccgcgctcagccgctggctgctggccgtgcccgccgccagagccttacccacaggagtgcacccgcgcctgcacgccgtgtgcgaggcgggcgcgcgcctgctggccgcgctcagccgctggctgctggccgtgcccgccgccagagccttacccacaggagtgcacccgcgcctgcacgccgtgtgcgaggcgggcgcgcgcctgctggccgcgctcagccgctggctgctggccgtgcccgccgccagagccttacccacaggagtgcacccgcgcctgcacgccgtgtgcgaggcgggcgcgcgcctgctggccgcgctcagccgctggctgctggccgtgcccgccgccagagccttacccacaggagtgcacccgcgcctgcacgccgtgtgcgaggcgggcgcgcgcctgctggccgcgctcagccgctggctgctggccgtgcccgccgccagagccttacccacaggagtgcacccgcgcctgcacgccgtgtgcgaggcgggcgcgcgcctgctggccgcgctcagccgctggctgctggccgtgcccgccgccagagccttacccacaggagtgcacccgcgcctgcacgccgtgtgcgaggcgggcgcgcgcctgctggccgcgctcagccgctggctgctggccgtgcccgccgccagagccttacccacaggagtgcacccgcgcctgcacgccgtgtgcgaggcgggcgcgcgcctgctggccgcgctcagccgctggctgctggccgtgcccgccgccagagccttacccacaggagtgcacccgcgcctgcacgccgtgtgcgaggcgggcgcgcgcctgctggccgcgctcagccgctggctgctggccgtgcccgccgccagagccttacccacaggagtgcacccgcgcctgcacgccgtgtgcgaggcgggcgcgcgcctgctggccgcgctcagccgctggctgctggccgtgcccgccgccagagccttacccacaggagtgcacccgcgcctgcacgccgtgtgcgaggcgggcgcgcgcctgctggccgcgctcagccgctggctgctggccgtgcccgccgccagagccttacccacaggagtgcacctgcgcctgcacgccgtgtgcgaggcgggcgcgcgcctgctggccgcgctcagccgctggctgctggccgtgcccgccgccagagccttacccacaggagtgcacccgcgcctgcacgccgtgtgcgaggcgggcgcgcgcctgctggccgcgctcagccgctggctgctggccgtgcccgccgccagagccttacccacaggagtgcacccgcgcctgcacgccgtgtgcgaggcgggcgcgcgcctgctggccgcgctcagcCGCTGGCTGCTGGCCGTGCCCGCCGCCAGAGCCTTACCcacaggagtgcacccgcgcctgcacgccgtgtgcgaggcgggcgcgcgcctgctggccgcgctcagccgctggctgctggccgtgcccgccgccagagccttacccacaggagtgcacccgcgcctgcacgccgtgtgcgaggcgggcgcgcgcctgctggccgcgctcagccgctggctgctggccgtgcccgccgccagagccttacccacaggagtgcacccgcgcctgcacgccgtgtgcgaggcgggcgcgcgcctgctggccgcgctcagcCGCTGGCTGCTGGCCGTGCCCGCCGCCAGAGCTTTACCcacaggagtgcacccgcgcctgcacgccgtgtgcgaggcgggcgcgcgcctgctggccgcgctcagcCGCTGGCTGCTGGCCGTGCCCGCCGCCAGAGCTTTACCcacaggagtgcacccgcgcctgcacgccgtgtgcgaggcgggcgcgcgcctgctggccgcgctcagccgctggctgctggccgtgcccgccgccagagccttacccacaggagtgcacccgcgcctgcacgccgtgtgcgaggcgggcgcgcgcctgctggccgcgctcagcCGCTGGCTGCTGGCCGTGCCCGCCGCCAGAGCTTTACCcacaggagtgcacccgcgcctgcacgccgtgtgcgaggcgggcgcgcgcctgctggccgcgctcagccgctggctgctggccgtgcccgccgccagagccttacccacaggagtgcacccgcgcctgcacgccgtgtgcgaggcgggcgcgcgcctgctggccgcgctcagcCGCTGGCTGCTGGCCGTGCCCGCCGCCAGAGCTTTACCcacaggagtgcacccgcgcctgcacgccgtgtgcgaggcgggcgcgcgcctgctggccgcgctcagccgctggctgctggccgtgcccgccgccagagccttacccacaggagtgcacccgcgcctgcacgccgtgtgcgaggcgggcgcgcgcctgctggccgcgctcagcCGCTGGCTGCTGGCCGTGCCCGCCGCCAGAGCTTTACCcacaggagtgcacccgcgcctgcacgccgtgtgcgaggcgggcgcgcgcctgctggccgcgctcagcCGCTGGCTGCTGGCCGTGCCCGCCGCCAGAGCTTTACCcacaggagtgcacccgcgcctgcacgccgtgtgcgaggcgggcgcgcgcctgctggccgcgctcagcCGCTGGCTGCTGGCCGTGCCCGCCGCCAGAGCTTTACCcacaggagtgcacccgcgcctgcacgccgtgtgcgaggcgggcgcgcgcctgctggccgcgctcagccgctggctgctggccgtgcccgccgccagagccttacccacaggagtgcacccgcgcctgcacgccgtgtgcgaggcgggcgcgcgcctgctggccgcgctcagcCGCTGGCTGCTGGCCGTGCCCGCCGCCAGAGCTTTACCcacaggagtgcacccgcgcctgcacgccgtgtgcgaggcgggcgcgcgcctgctggccgcgctcagccgctggctgctggccgtgcccgccgccagagccttacccacaggagtgcacccgcgcctgcacgccgtgtgcgaggcgggcgcgcgcctgctggccgcgctcagcCGCTGGCTGCTGGCCGTGCCCGCCGCCAGAGCTTTACCcacaggagtgcacccgcgcctgcacgccgtgtgcgaggcgggcgcgcgcctgctggccgcgctcagccgctggctgctggccgtgcccgccgccagagccttacccacaggagtgcacccgcgcctgcacgccgtgtgcgaggcgggcgcgcgcctgctggccgcgctcagccgctggctgctggccgtgcccgccgccagagccttacccacaggagtgcacccgcgcctgcacgccgtgtgcgaggcgggcgcgcgcctgctggccgcgctcagccgctggctgctggccgtgcccgccgccagagccttacccacaggagtgcacccgcgcctgcacgccgtgtgcgaggcgggcgcgcgcctgctggccgcgctcagcCGCTGGCTGCTGGCCGTGCCCGCCGCCAGAGCCTTACCATTTGAGATCCAAGTGACGCTCCTCAAGAAATGCTGGCCGGAGCTCTTCGTGCTGGGTCTAGCCAAGTTCTCCGCCGCGCTGCAGCTGACTGCCCTGCTGCCGCAGATGGTGGCGCATCTCCAGGCGGTGCTGAGGGAGCGAGCCGGCAATACCGAGTGCGAGCGAGAGCGCGGCGCTGAGATAACCACAGCGGATTATTCCGACGAGCGAGTGTCGGAAGTGAGCAGCATGCTGTCTCGCTTGCAACAATACATCGGCAACATGGAGCAGCTGCGAGTGAGCGAGAGGGAACATGCGCATTTACGAGCGCTGTGCCTGTTTTCACCAGACGGCGCCCCAGACTTCCTAACCAAGAAGCTCCAAGAGCTCCAATCGTCCGTCCTTCGTTCCCTCCGCGCGCTATGCGCGTCAGACGAGGACCGCTGCGCGACCATCCTGCTCCAACTGCCGGTGCTCCGCGCGTTCACGGGACCCTTTCTTGAGGATGTGTTCTTTGTAGGATTTGTAGGTGATGTCAGCATCGATGACGTCGTGCCGTATTTACTGAACGCGGAGCGCTGA
Protein Sequence: MDGQDQMEMKFSGGSEVGGMELCIVCGDRASGRHYGAISCEGCKGFFKRSIRKKLGYQCRGSMNCEVTKHHRNRCQYCRLQKCLACGMRSDSVQHERKPIVDKVKPERGEGLHERQAYSKLLGLAGQQGPINPKEEPGEFGAAPAPAINFALAAAVAFNKGNPVPGYLGAGDVEGARRQQLLLQTQLAKNLFKMGQFGAINEYLQSAYAAPEAPQLPQADAPQPEVADPSAVLCTAESLALQLALPAGAPPHLRLHAVCEAGARLLAALSRWLLAVPAARALPTGVHPRLHAVCEAGARLLAALSRWLLAVPAARALPTGVHPRLHAVCEAGARLLAALSRWLLAVPAARALPTGVHPRLHAVCEAGARLLAALSRWLLAVPAARALPTGVHPRLHAVCEAGARLLAALSRWLLAVPAARALPTGVHPRLHAVCEAGARLLAALSRWLLAVPAARALPTGVHPRLHAVCEAGARLLAALSRWLLAVPAARALPTGVHPRLHAVCEAGARLLAALSRWLLAVPAARALPTGVHPRLHAVCEAGARLLAALSRWLLAVPAARALPTGVHPRLHAVCEAGARLLAALSRWLLAVPAARALPTGVHPRLHAVCEAGARLLAALSRWLLAVPAARALPTGVHLRLHAVCEAGARLLAALSRWLLAVPAARALPTGVHPRLHAVCEAGARLLAALSRWLLAVPAARALPTGVHPRLHAVCEAGARLLAALSRWLLAVPAARALPTGVHPRLHAVCEAGARLLAALSRWLLAVPAARALPTGVHPRLHAVCEAGARLLAALSRWLLAVPAARALPTGVHPRLHAVCEAGARLLAALSRWLLAVPAARALPTGVHPRLHAVCEAGARLLAALSRWLLAVPAARALPTGVHPRLHAVCEAGARLLAALSRWLLAVPAARALPTGVHPRLHAVCEAGARLLAALSRWLLAVPAARALPTGVHPRLHAVCEAGARLLAALSRWLLAVPAARALPTGVHPRLHAVCEAGARLLAALSRWLLAVPAARALPTGVHPRLHAVCEAGARLLAALSRWLLAVPAARALPTGVHPRLHAVCEAGARLLAALSRWLLAVPAARALPTGVHPRLHAVCEAGARLLAALSRWLLAVPAARALPTGVHPRLHAVCEAGARLLAALSRWLLAVPAARALPTGVHPRLHAVCEAGARLLAALSRWLLAVPAARALPTGVHPRLHAVCEAGARLLAALSRWLLAVPAARALPTGVHPRLHAVCEAGARLLAALSRWLLAVPAARALPTGVHPRLHAVCEAGARLLAALSRWLLAVPAARALPTGVHPRLHAVCEAGARLLAALSRWLLAVPAARALPTGVHPRLHAVCEAGARLLAALSRWLLAVPAARALPTGVHPRLHAVCEAGARLLAALSRWLLAVPAARALPTGVHPRLHAVCEAGARLLAALSRWLLAVPAARALPFEIQVTLLKKCWPELFVLGLAKFSAALQLTALLPQMVAHLQAVLRERAGNTECERERGAEITTADYSDERVSEVSSMLSRLQQYIGNMEQLRVSEREHAHLRALCLFSPDGAPDFLTKKLQELQSSVLRSLRALCASDEDRCATILLQLPVLRAFTGPFLEDVFFVGFVGDVSIDDVVPYLLNAER

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -