Basic Information

Insect: Latheticus oryzae
Gene Symbol: topi
Assembly: GCA_030157265.1
Location: CM058049.1:7337637-7339811[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.007 0.51 10.8 1.9 2 21 95 114 94 115 0.94

2 14 1e-06 7.6e-05 22.9 1.3 1 23 140 162 140 162 0.97

3 14 0.018 1.3 9.6 3.5 2 23 169 190 168 190 0.95

4 14 0.012 0.87 10.1 0.5 2 15 209 222 208 229 0.84

5 14 0.0012 0.085 13.3 1.2 2 23 267 288 266 288 0.97

6 14 0.25 18 6.0 0.1 1 19 294 312 294 315 0.82

7 14 0.35 26 5.5 3.0 2 21 331 350 330 354 0.83

8 14 0.16 11 6.6 0.2 1 23 470 493 470 493 0.96

9 14 0.012 0.84 10.2 0.2 1 23 497 519 497 519 0.96

10 14 6.1e-07 4.5e-05 23.6 2.4 1 23 525 547 525 547 0.98

11 14 0.017 1.2 9.6 0.2 1 23 553 578 553 578 0.96

12 14 0.036 2.6 8.6 2.7 1 23 584 606 584 606 0.86

13 14 5.5e-05 0.004 17.5 0.5 3 23 614 634 612 634 0.97

14 14 0.00031 0.022 15.1 1.7 1 23 640 663 640 663 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.007	0.51	10.8	1.9	2	21	95	114	94	115	0.94
2	14	1e-06	7.6e-05	22.9	1.3	1	23	140	162	140	162	0.97
3	14	0.018	1.3	9.6	3.5	2	23	169	190	168	190	0.95
4	14	0.012	0.87	10.1	0.5	2	15	209	222	208	229	0.84
5	14	0.0012	0.085	13.3	1.2	2	23	267	288	266	288	0.97
6	14	0.25	18	6.0	0.1	1	19	294	312	294	315	0.82
7	14	0.35	26	5.5	3.0	2	21	331	350	330	354	0.83
8	14	0.16	11	6.6	0.2	1	23	470	493	470	493	0.96
9	14	0.012	0.84	10.2	0.2	1	23	497	519	497	519	0.96
10	14	6.1e-07	4.5e-05	23.6	2.4	1	23	525	547	525	547	0.98
11	14	0.017	1.2	9.6	0.2	1	23	553	578	553	578	0.96
12	14	0.036	2.6	8.6	2.7	1	23	584	606	584	606	0.86
13	14	5.5e-05	0.004	17.5	0.5	3	23	614	634	612	634	0.97
14	14	0.00031	0.022	15.1	1.7	1	23	640	663	640	663	0.98

Sequence Information

Coding Sequence: ATGCTCAGCGCTGAGAATCGAACACTTTCTGTGATAAATGCACATTTCATAAGCGACTTTGGGAAAATTTCCTCGATGCGGTATGAAGCTGACTTTATTACCtacaaaataattagtaaaagTCCATTTTTAACTGAAAAGAATATAAGTTTTAACTTAAGCGAAGAGATTAATTTCAGTCATCAATCTCTTTTTAATGAAGATTTGGGTCCAGTTCAACTTCATAGAGTAGAAGGTAATCCAAATTTGAACAAGCACAGAATGAACATCCCAACAATGATCAGGTGCCAAAATTGCGAAACTAATTATCCCACAAAGTACCAATACCAAAGACACCAATGCGAATTCAATGCGGAAAAAGTGGTCCTCAAACCAAACGCCGACTTTATCGATGGAGAAAAAGGTAAACGCATCAAGTACGATTGTTCTACATGCGGAAAACAATTTGTTAGTAAAAACAATTTGGAACGTCACCAAACAAGTCACGAAAGCTCCAATAATAAAACTTGCGAGCATtgcaaaaaacaatttgtcaGTGAAAATCGCTTAAGAATACATAAAGAAAACCATTGCAAAAAAGCGGgagatatttcaaaattttacagaagCGATGTTACTGTAtggaaatgtaaaaaatgccATGAAGTTTTCTCATCGAGTTCTACTGCTGGATACCACGTAGAAAGTTGCACTGAAATAATCGAcaacgaaataaaaaaagaaccTTTGAGTGAAAACAGTGAACAAAACACCAAACCTGacaaaactattgaaaaaatatcaacagaaATTCTTCTCCAATGTGAATTTTGTAATAGAACTTACGCTGATAAGcaaattttactaaaacatcaaaaaactCACAAAACTGATAAGAATTACGAATGCGTCATTTGCAAAGAAACTTTTGAATCGTACATAACCGCTTCCCAACATTGGCTGAAGAAATGTTCGGAAAAAGCAAATCTTTTCTATTTACCTAAATTGACTTATTGTGAATTTTGCGATCGTACTTTTAAATCGCACGAAATTCTTTATactcataaaattaaaaagaagcATTATACGCCAAAAGCGCATGATATTAGCGGCATTGAGAAAAGTAATCAAGTTAAAGATATCAAGAGTGAGGATGTTATTGATAAATTGATTGAAGATGTCTTAACAGCTTTAGAAATACCAGTAAACAAACGAATGAAAAAATGCGTTGAAAAAAGAGAAGaagataaagaaaatataGTTTGTGAGGAAGAAAATGCTAAAGTGAAGATAGAACCAACGAGCCATACTACTGACCAAGAGGAAGTTTCTGTTcctgaaaagaaaaaacgcGGTCGAAAGAGGAAGTTTCCAAAACAGCAGCCAAAATTCAAGAAACCTTCTGTTGTTCTGGATGAAGGGTATAAATATCAATGTGAACGATGTACTGAAGTTTGGAACACTATCACTGAATTGGAAAATCACAGAGAGAAAGAACACGCAGCAAATTTCAACTGCGACGAATGCGGCCAAGTTTTGCATAGCGCTCGAGCACTTTTAATTCATAGCCGAGCTCATAAAAGCTTAAAGCCTTATGTTTGTGATACATGCGGTAGAAGTTACTCGCAAACTTCTCATTTGTGGCAACACATGAGATTCCATCAAGGCATAAAACCTTTTGCTTGTCCTCATGAGGGCTGCGAAGCTCGATACACTATCCGCCCGGATTTGAAAGACCACATTCGGAAAGTTCATACAAGAGAAAGACCTTTCAAATGCAGTGTCTGTGGTAAATGTTTCCTGACAGGATCAGTTTACTATCAACATCGATTAATCCACACCGAGGACAGACGCTATGGATGCGATatgTGTGAGAAGAGATTCTTCAGAGCTGACGCTTTAAATAATCACAAGAGAATTCATACGAATGAAAGACCGTATCCTTGTTTTGTTTGTGGAAGATTGTTTAGACAGAAAGGAGATAGGAATAAACACTTCAGGACACAACACCCTGATGCAATTACCAACTAA
Protein Sequence: MLSAENRTLSVINAHFISDFGKISSMRYEADFITYKIISKSPFLTEKNISFNLSEEINFSHQSLFNEDLGPVQLHRVEGNPNLNKHRMNIPTMIRCQNCETNYPTKYQYQRHQCEFNAEKVVLKPNADFIDGEKGKRIKYDCSTCGKQFVSKNNLERHQTSHESSNNKTCEHCKKQFVSENRLRIHKENHCKKAGDISKFYRSDVTVWKCKKCHEVFSSSSTAGYHVESCTEIIDNEIKKEPLSENSEQNTKPDKTIEKISTEILLQCEFCNRTYADKQILLKHQKTHKTDKNYECVICKETFESYITASQHWLKKCSEKANLFYLPKLTYCEFCDRTFKSHEILYTHKIKKKHYTPKAHDISGIEKSNQVKDIKSEDVIDKLIEDVLTALEIPVNKRMKKCVEKREEDKENIVCEEENAKVKIEPTSHTTDQEEVSVPEKKKRGRKRKFPKQQPKFKKPSVVLDEGYKYQCERCTEVWNTITELENHREKEHAANFNCDECGQVLHSARALLIHSRAHKSLKPYVCDTCGRSYSQTSHLWQHMRFHQGIKPFACPHEGCEARYTIRPDLKDHIRKVHTRERPFKCSVCGKCFLTGSVYYQHRLIHTEDRRYGCDMCEKRFFRADALNNHKRIHTNERPYPCFVCGRLFRQKGDRNKHFRTQHPDAITN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01481174;
90% Identity: -
80% Identity: -