Lfle022037.1
Basic Information
- Insect
- Laspeyria flexula
- Gene Symbol
- -
- Assembly
- GCA_905147015.1
- Location
- LR989960.1:2108190-2114510[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 2.2 1.5e+02 3.5 0.4 2 23 6 27 5 27 0.96 2 14 0.92 64 4.7 0.0 1 23 1002 1025 1002 1025 0.90 3 14 7.7 5.4e+02 1.8 0.1 1 23 1098 1120 1098 1120 0.85 4 14 9.2e-06 0.00063 20.5 2.2 2 23 1123 1144 1122 1144 0.97 5 14 0.00026 0.018 15.9 3.0 1 23 1150 1172 1150 1172 0.98 6 14 0.011 0.73 10.8 3.0 2 23 1179 1200 1178 1201 0.94 7 14 0.35 24 6.0 0.1 6 23 1215 1232 1214 1232 0.98 8 14 0.019 1.3 10.0 1.1 3 23 1239 1260 1238 1260 0.96 9 14 0.11 7.8 7.6 0.2 3 23 1275 1294 1274 1294 0.96 10 14 0.00026 0.018 15.9 3.1 1 20 1300 1319 1300 1322 0.89 11 14 0.0017 0.12 13.3 0.1 1 23 1330 1352 1330 1352 0.98 12 14 0.0012 0.082 13.8 4.5 1 23 1358 1380 1358 1380 0.98 13 14 1.5e-05 0.0011 19.8 0.7 1 23 1386 1410 1386 1410 0.94 14 14 0.0019 0.13 13.1 4.2 1 23 1416 1438 1416 1439 0.95
Sequence Information
- Coding Sequence
- ATGGACCAGCTCGTGCAGTGTCCCGTGTGCACGCTGTTTCTGCACAATGGCATGACCCTAGAGTCACATCTGGATACACATCCTAAAGATCAAGTTATTAAAGCACTATGTAATTTGACAACACCTAAGGCTCCTAGTTATGGAAGTAGGACTTCCACCCCTTTACATTCTGAAAGGTCATACAGAAGTAGGTCACGGACACCGGCCACAGATGAGAGCAGATGGAATGGGTCCCACAGAAGTGATGACCGCTACTGGCGTAGAACTCCTAGTAGAACCCCGAAGGCCAGTGCGATGCCAAGTGCATCTAGACATGGAACACCAGACATCCATCATATAAATTTTGATAACAATAGTGGGCCGGGTAATGGAGCACAACTTTCAGGGCCACCGTTTGTAATGAAAGCTGATAAGTTCCAACAGACATACCAGTCTCCTCCAATATCTGATTATGATTCTCAGTACATTTACTATGAACAACCAGAGGACAGGGAGGTTAAGTACTCTCGCAGTGCTGAGTACAATTCTATGAGCAGTCCCAACAATATGTATGCCTACAACCATGTCATTCCATCCGTAGGACCAGCTGTCAAGTTGGTACCAGCCACTCCTAAAAGAGGAAACGACCTTCAGAAAATTTTACCTAAACCAAATAATATACTGCTTAAAAATATGGGTGGTGTGCAATATATTAGTCCAGGATCTAAACCAATGCATGTTATGATGCCAAGTGCATCAACGTTTGTTCAGAAAAATGTTCAAAACAATATGATAATGGCAGGTGGTGTGCCAAACCTGCAGATTCAAATAGACAGCAAATCAGGAGCACCCCCTCTGGCCAGCAACCAACTAAACCAAATGAGTTCTGGTGCATTCACCCCAGGTACTACTGTGGTTACTCAGAACTCACAAATTATTTACAGAGAAATGGTAAACAATGTTGATGGTAAGCCCTTTATAACTAGCATGCCCACTATTCTAGGTGCTCATGATAATGTCACAAATTTAGCTCAAACTAGTTCATTGTACCAAAATGTAATGGTTGTTGATCAGTTTGGAAATACCTCATGTATGTATGCATCACCTCCGCAAATAATACCCAAGTGTCCCACGTCTGTGTACAATGAAACACCATCTCTAGCGTCTAGTTCTATGCATGTAGAGAAAGCTTCAGGTAATACAAATGACCCTAAAACTCTCATTATTGAGGTAGGGCCCATAGGTCCTCCAGGGCCAGACAAACTGTGTAAGCCTTCCACTTCTTCACACTCAAACACCAATAGTCCAGTTGAAAAACCTGACAAACAAATAAATGACAATGTTGAAACTAAGAGTGAAACGCCTGGTTCTACCAAAGGCTTAAAAATACTTAGTAACATAAAAGTTGAAGTTCCAGTACAGCATCATAAAAACATGGTGAACACTGTGATGGACCTCACAGGGCCTAATGACTCTGAATATCCTGTGGAACGAGTGCCTTCACCAGAAAAGATTTTGCCAGACTTAGATGACAGTGACAATCATCAAAGTTTGTCCAATGAGAGTATACAGCCATCTGACTCGAGTGCTGACAGTGTTCCATCCTCATTTGGTGTCATAAAGACTAAGTCGTCACTGAAAGATTCAAATAAAAGTCCTGTTGAAAGTAAAGCGGACATAGAGTTCTCAGACAGCTGTCCCGTGCCAGATCTAATCTGTAATGAGAAGCCGTCAATATCACCTTGTAGTGAGTTGTCAGAGAATGGTGATAACTCAACCGATCATACCTCAATATCTCCTAAACCTGTGAGTAGTGAAGTTAGCCATAGTAATATAGATTCTCCAGAAAAGAAAAAACAGCTTCCACAGAAGCCATACAGGCACAACCCATTAAGACTGAACAATATTTATGTGAAGAAAAATAAGAAAGTTTTGCAAATTAAGAATTCCAAGGGGTTTCCAGTAGGTAGTTCATGTAAAAAGGAAGAACCTATAGCTTCGTCATCTTGTGGCAAGGCACCTGAAAATTTTACAATGAATATATTGCATCATACAGATAAAAGTGAAAGTAAAGAAAAGTCTAGTGTTTTAACAACAATATCAGTAGAGGAGATCAAGGAGAATGATGATAATAACGAGTTTGATGCTGACACAGAGGAGCAGTCCATGGACATAGAACCAGTGGCCCCTTCCAGTATGCGTCATGAACAGAACAACTTCACCACAAGCACAGTCATTGTGAAGGAGGACGTGAAGGAGGAAATCAATACTAGTAATGAAGGGGGATTTAGTAATCATACGGCTACATCAGACCGCGAGCTCGCACCTCTAGAAACTTTGCGTCCAATCAATGTTGTTCCCTACGCAAACATGTCGGCAGATTTCGACGAAGACTCGAATGATAAGGAACTGCTTGATCTTGAAACCACGTCAAAGAACAAACAGTTTGTTAATATGATGAACGAGAACTACTTCGGCGACAATATCTATGTGGACTACTTCACGCCGGACCGAGTGGAGTCGTTCGACGCGGCGCGCGGGTCGGCAGGATTCAAGGATGGTCCTAAAGAGGGTATGTATAATATTTGGGGTGAACCGTCTCAGAAAGAGAACGAGAATGAGTTTGTTTTACCTAACTTTATACACGAGAGCTACAAAATAGCGGAGAGTAGTGGAATAGATTACTCAGAGATTGGTAGAGAAGGACAAGGTGATGGCGAGGGTGATGGGTGTGAGCGAGACAGCAAGGTGGATGTGTTGAGCGAAGGTCGCAGTGAAGGGGACACGCCGCTCAACATCTGCGCCGACGAGCGCATGCCGCCCCGCGGAGAGCTCAGCGGACAGGAGAGCAACGGAGACATGGAGTCACCTTGGGGCGGGATGTACACGGACGTGCCGGCGACAGAGCCGTACGATCTCATCGCAAGAGAGAGCTGGGTGTCAGACGGGTCTGACGTGGACGTCAGCGAGAAGAGAGAAACACTTGAGGAAGAGCTGCAATTCCCCAAGGCGCTGGGGCGCGTGTACTCGTGCGCGCTGTGCGACGTGAAGGCGGCGTCGCTCAAGGAGCTGCGCGCGCACAAGGCGGCGGCGCACGCCCCCCCCCACACCTACAGCCGCCTCGTCACCGACCGCAAGATCAAGAAGGAGGAGAAGTCGCACGACGCCGTCGCACTCTCTGGCAACCTATTGGGGATAGACTCGAAGGAGCCGATCACATCGACGATCTTACAAGTGTACGACACTCTGGAGGAAGCTAAGCCGAAGATTGAGGGTCTGATCAAGCAGGAGACGAAGAGAAGACGGAAAAACTACGTGTGTCCTACGTGTAAAGTGAACCAGGGGTCTGACGCCGCGTTCAACGCTCATCTCAAGATACATCCCTTGGAGTGCCTCACGTGTGGCAAGTGCTTCTTTAGAAGAGCGAACTTGGCACTGCATATGAAAACACATTTAGGAATTAAGAATTACAAGTGCGACATGTGCGAGAAGCGGTTCATAACTCGACAGAAGTTGATGGAGCACCACAACGTGCACACGGGCCGCCAGCCCATCAAGTGCACCATGTGTGACGACACCTTCCGCAGATACTCCAACATGGTACAGCACAGGGACCGGCACCACCTCGGCAAGCGCGCGCGCGTGCGCGACTTCGTGTGCGCGTGCGGCGCCGTGTTCCACTCGCGCGCCAAGCTGGCGTGGCACCGCGAGACGCACGACGAGCGCCCCAAGGCCTGCCTCTACTGCAGCGACAAGTTCGTGCACGCCGCCTCGCTCACGCGCCACGTGCGGCGCTCGCACAACGAGTGCCTGGCGGCCGAGCGCGGCAAGGACAACGTGGCGTGCCCCGTGTGCAAGCAGCTGTACCTGCGCGGCAACCTGCGCGCGCACGTGCGCACGCACTCGGGCGCGCGCCCGCACGCCTGCGTCGTGTGCGGCAAGTGCTTCAGCACCAAGTGGAACCTCAAGCTGCACCGCTGGACGCACGCGGCGCGCTCGGCCAAGCCCTTCCGCTGCGCGCTGTGCCAGGCCGCCTTCGTACGGCGCGCCGAGTTCGCGTCGCACATGAACGCGCACCGCGCCGTGCGCCCCTACACGTGCAACCACTGCGGCGCGCGCTTCGTGCGCAAGTACAACTGCGCGCGCCACGTGCGGGAGCACGAGCAGGCCAAGCGCTTCGTGTGCGCCGTGCCCGACTGCGGCAAGTCCTTCCACCGCTCCTACTACCTGTCCGAGCACATGAAGGTGCACTCGGGCGCGCGCCCCTTCGCCTGCAACGTGTGCGGCAAGACCTCCAGCAACAAGTCCAACCACAACAAGCACGTCAAGATCCACCACGCGCGGGAGCCCGTCGCCACCGAGGCCTAG
- Protein Sequence
- MDQLVQCPVCTLFLHNGMTLESHLDTHPKDQVIKALCNLTTPKAPSYGSRTSTPLHSERSYRSRSRTPATDESRWNGSHRSDDRYWRRTPSRTPKASAMPSASRHGTPDIHHINFDNNSGPGNGAQLSGPPFVMKADKFQQTYQSPPISDYDSQYIYYEQPEDREVKYSRSAEYNSMSSPNNMYAYNHVIPSVGPAVKLVPATPKRGNDLQKILPKPNNILLKNMGGVQYISPGSKPMHVMMPSASTFVQKNVQNNMIMAGGVPNLQIQIDSKSGAPPLASNQLNQMSSGAFTPGTTVVTQNSQIIYREMVNNVDGKPFITSMPTILGAHDNVTNLAQTSSLYQNVMVVDQFGNTSCMYASPPQIIPKCPTSVYNETPSLASSSMHVEKASGNTNDPKTLIIEVGPIGPPGPDKLCKPSTSSHSNTNSPVEKPDKQINDNVETKSETPGSTKGLKILSNIKVEVPVQHHKNMVNTVMDLTGPNDSEYPVERVPSPEKILPDLDDSDNHQSLSNESIQPSDSSADSVPSSFGVIKTKSSLKDSNKSPVESKADIEFSDSCPVPDLICNEKPSISPCSELSENGDNSTDHTSISPKPVSSEVSHSNIDSPEKKKQLPQKPYRHNPLRLNNIYVKKNKKVLQIKNSKGFPVGSSCKKEEPIASSSCGKAPENFTMNILHHTDKSESKEKSSVLTTISVEEIKENDDNNEFDADTEEQSMDIEPVAPSSMRHEQNNFTTSTVIVKEDVKEEINTSNEGGFSNHTATSDRELAPLETLRPINVVPYANMSADFDEDSNDKELLDLETTSKNKQFVNMMNENYFGDNIYVDYFTPDRVESFDAARGSAGFKDGPKEGMYNIWGEPSQKENENEFVLPNFIHESYKIAESSGIDYSEIGREGQGDGEGDGCERDSKVDVLSEGRSEGDTPLNICADERMPPRGELSGQESNGDMESPWGGMYTDVPATEPYDLIARESWVSDGSDVDVSEKRETLEEELQFPKALGRVYSCALCDVKAASLKELRAHKAAAHAPPHTYSRLVTDRKIKKEEKSHDAVALSGNLLGIDSKEPITSTILQVYDTLEEAKPKIEGLIKQETKRRRKNYVCPTCKVNQGSDAAFNAHLKIHPLECLTCGKCFFRRANLALHMKTHLGIKNYKCDMCEKRFITRQKLMEHHNVHTGRQPIKCTMCDDTFRRYSNMVQHRDRHHLGKRARVRDFVCACGAVFHSRAKLAWHRETHDERPKACLYCSDKFVHAASLTRHVRRSHNECLAAERGKDNVACPVCKQLYLRGNLRAHVRTHSGARPHACVVCGKCFSTKWNLKLHRWTHAARSAKPFRCALCQAAFVRRAEFASHMNAHRAVRPYTCNHCGARFVRKYNCARHVREHEQAKRFVCAVPDCGKSFHRSYYLSEHMKVHSGARPFACNVCGKTSSNKSNHNKHVKIHHAREPVATEA
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00281692;
- 90% Identity
- -
- 80% Identity
- -