Basic Information

Gene Symbol
-
Assembly
GCA_905147015.1
Location
LR989975.1:925434-928186[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 0.0039 0.27 12.2 0.3 1 23 219 242 219 242 0.94
2 17 0.00011 0.0079 17.0 4.8 1 23 247 269 247 269 0.98
3 17 0.00092 0.064 14.2 0.6 1 23 299 322 299 322 0.95
4 17 0.0024 0.17 12.8 0.6 3 23 384 405 382 405 0.95
5 17 0.00044 0.03 15.2 1.0 1 23 411 434 411 434 0.93
6 17 0.0012 0.081 13.8 0.3 3 21 439 457 437 458 0.93
7 17 2.6 1.8e+02 3.3 0.0 3 23 468 489 468 489 0.94
8 17 3.6 2.5e+02 2.8 2.7 1 23 494 517 494 517 0.91
9 17 0.0079 0.54 11.2 0.1 2 23 530 551 529 551 0.96
10 17 0.0075 0.52 11.3 2.3 1 23 557 579 557 579 0.97
11 17 0.0086 0.59 11.1 2.0 1 23 615 637 615 637 0.96
12 17 0.037 2.6 9.1 1.4 3 23 643 663 642 663 0.93
13 17 0.0011 0.079 13.9 2.0 2 23 676 698 675 698 0.96
14 17 0.0018 0.13 13.2 2.7 1 23 704 726 704 726 0.98
15 17 0.00011 0.0078 17.0 5.4 2 23 733 754 732 754 0.96
16 17 2e-05 0.0014 19.4 1.4 1 23 760 783 760 783 0.97
17 17 0.51 35 5.5 1.3 3 23 790 811 788 811 0.95

Sequence Information

Coding Sequence
ATGGAGGACTTTGTAGTAACAAAAGATCCTGAGAAGTTACTGAAGTTGGACTGGTTGAAAAAAAAACTAAATGCACTATGGTCATCAGCCAAATTCTGTGGCCTTTGTTTGGAGAATACAGGAAACTTTAGCTCCATAGACATGGAGCTGGTCATCAATAAACAAAACTTTTCAAGCTGTCTTCGGGACATCATAAATTATGTTTTTAATGATGATGTTGACAATTTAATGTTGAGTCACTACTTATGTGACAATTGCACAGAAACTACCATACAATCTTACATCTTTATACACAACACAAAACAAGTATCAAAAATTATAAATAGCTGTGTGAACGATATTTACTCAAAAGTCATTGATGTAAATGAACAAGTTAGTCGTTCAACTGACTTTGACAATGCCAACGTAATGATTATTTTAGAGAATGATGTTGACTTTTACAAAACATTACCAGCCGCCACTCCTATAGCCATGAGAGTGGAACAGCCTAAGAAAGTAGCAGTTATATCTAAGGTAGAAACAATCAAAGAGCCCATCAAAGTTGAATGTGAACAGATAAAGTCTGAACCCACACCAAATATAACTTTAAAAGATGGACATATAGTTATAAAACCATTGAATTCGAATAGGACTTTGACGCCCCGTTACAATACGTATGAATGTGCTAGCTGTCCAGAGATTTTTACTACTTATCGATCGTTAAAAGAACATGAAAAGGCCAAACATAACAAGTCAGTCTTCCATTGTAATCTTTGTGACAAGTCATACAACACTCGTCAATATCTGAACATACATTATAAGACTCATTCTAAAGCAAAATGCAAATTTTGTCAGCAAATATTACCTGAAACGGAATTAATGGAACATTTGAGAGCAAATCATGCATATTTAGTGTTCCCATGTAAGTTTTGTGACTTAGTATATTATACACAAGATACGTTGATCACACATTTCAATATCAGTCATTTGGTTAACAATACCAAAGTAAAGTCTCAATGTATTATGTGTTTAAAGATTCTCAAAGATACTGAAATGAAAAAACATAAATGCAAGTTTGCGTGTTCTGAATGTTTTGTGATGCCATGCATACATTATAAGTATCTAATGTCCTATCGAGAGCAAACATTGAACCATGCAAACAAAGTCAATTGTATGGACTGTGACTATGTTACTAGGAGGAAGGAACATTTGATAGGACATGTGAATAGAGAGCATTTGGATCATCACCCATTTACTTGTGCTGATTGTGGTCAGCAATTCTACACTAAGCTTAGTTTGAAAACCCATATTGTACAATTTCATCAAGACATTAACTGTGAATACTGTGATTTTGAATTTAAAGACAATAATTCTTTGGAGAATCATAAAAAAGTGTGTAAGTCAGTTAGAAGGGCATTGGGCTGTAATCAATGTGTCGCTTCCTTTGATTTGGAAGAAGAACTTGTTGCTCATGAGAATTTGAGACATAGTGAGAGTGTTCATGCATGTAATCTTTGTAAAAGTAAGTTCTTGACTAATATGGAGCTACAGGAACATCACGCGAGAGTGCATGGGGGTATCCAATGTAAAAAGCGAAGGAAACACATAGAATGTTCAGTATGCGACATCATGTTTAAAAACATCAAAGAAATGGTTCAGCATGAGAAAATTCATGAACCAGATGAGATGTACCCATGTAAGGTATGTTCAAAACAGTTTAAGAGCTTGATGAAGTTGTATATGCACAATCAGAAGCACTACACCAACAGGATTAAGTGTACTCGGTGTAATAAAAATGTGGCAGCTTCATTCTACCCTCAACATGCAGTCAGGTGTCCATACAAAAGAGAAGCAACTTTGAGTCACGTTTGTGAAGTCTGCGGAAAAGCTTTCCATCTAGAATCATTGTTACGTTTCCACCAAAAAGTCCATATGGAGCGAGAACCGTGTCCACAGTGTGACAAATGTATGAAACCGACCAGCTTAAAGAGACACATGGAACAAATCCATGGAGATGAAAAGAAAGCAACACAGAAGCCAGTCATACAATGTAAATTATGCGGTCATGTAGTGAGAAAAAAACATGATCTTGAAGCACATGTAAACAGATACCACCTGAAGATTAAACCATATATTTGTCATATATGCAGCAAGGACTTCTGTGGAAAGATTCGGTTGAAGGAACATATAGCAACGCATACAACTGACAATAGCTGCTTCTGTCCAGAGTGTGGCAAGAAGTTTGCTAACCGTGTTTGTTTGAAAATGCACTATAGAAGGCATACTGGAGAGGCACCGTATCCTTGTGATATATGCGGTCAGAAGTTCCGATCTTCTAGTATGATGAAGACTCACCGATTGAAGAAGCATTTGGAGAAAACAGTTTGCTGCCCGCTATGTGACAGTATGTTTTATATGGCAAGAGATATGAGACTTCACTTCAAGAAAGTTCACTGGAAATTCAAAGATAGGCCTTTTGATGTTAGAGAGGTTAAGGAACTAGATAAAGACTACTATTACTTGTTTGAAGATGGACGATTGCCTAAATTGGATTCTTGA
Protein Sequence
MEDFVVTKDPEKLLKLDWLKKKLNALWSSAKFCGLCLENTGNFSSIDMELVINKQNFSSCLRDIINYVFNDDVDNLMLSHYLCDNCTETTIQSYIFIHNTKQVSKIINSCVNDIYSKVIDVNEQVSRSTDFDNANVMIILENDVDFYKTLPAATPIAMRVEQPKKVAVISKVETIKEPIKVECEQIKSEPTPNITLKDGHIVIKPLNSNRTLTPRYNTYECASCPEIFTTYRSLKEHEKAKHNKSVFHCNLCDKSYNTRQYLNIHYKTHSKAKCKFCQQILPETELMEHLRANHAYLVFPCKFCDLVYYTQDTLITHFNISHLVNNTKVKSQCIMCLKILKDTEMKKHKCKFACSECFVMPCIHYKYLMSYREQTLNHANKVNCMDCDYVTRRKEHLIGHVNREHLDHHPFTCADCGQQFYTKLSLKTHIVQFHQDINCEYCDFEFKDNNSLENHKKVCKSVRRALGCNQCVASFDLEEELVAHENLRHSESVHACNLCKSKFLTNMELQEHHARVHGGIQCKKRRKHIECSVCDIMFKNIKEMVQHEKIHEPDEMYPCKVCSKQFKSLMKLYMHNQKHYTNRIKCTRCNKNVAASFYPQHAVRCPYKREATLSHVCEVCGKAFHLESLLRFHQKVHMEREPCPQCDKCMKPTSLKRHMEQIHGDEKKATQKPVIQCKLCGHVVRKKHDLEAHVNRYHLKIKPYICHICSKDFCGKIRLKEHIATHTTDNSCFCPECGKKFANRVCLKMHYRRHTGEAPYPCDICGQKFRSSSMMKTHRLKKHLEKTVCCPLCDSMFYMARDMRLHFKKVHWKFKDRPFDVREVKELDKDYYYLFEDGRLPKLDS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00281660;
90% Identity
-
80% Identity
-