Lfle017555.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Laspeyria flexula
Gene Symbol
ZFX
Assembly
GCA_905147015.1
Location
LR989975.1:1887575-1890581[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 0.041 2.8 9.0 7.1 1 23 149 172 149 172 0.95
2 18 6.1e-05 0.0043 17.9 0.3 2 23 182 204 181 204 0.97
3 18 0.014 0.94 10.5 0.4 2 23 217 239 217 239 0.97
4 18 0.00069 0.048 14.5 1.0 1 23 248 271 248 271 0.96
5 18 0.0043 0.3 12.0 3.1 1 23 283 306 283 306 0.96
6 18 4.7e-05 0.0033 18.2 0.8 2 23 334 356 333 356 0.97
7 18 0.0013 0.092 13.7 1.2 2 23 366 388 365 388 0.96
8 18 0.093 6.5 7.8 1.8 3 20 394 411 392 413 0.91
9 18 0.00084 0.058 14.3 0.5 2 21 418 437 417 440 0.94
10 18 0.2 14 6.8 1.6 3 23 450 471 448 471 0.92
11 18 0.00026 0.018 15.9 3.5 1 23 476 499 476 499 0.94
12 18 0.00074 0.051 14.5 1.6 2 23 511 533 510 533 0.95
13 18 0.00017 0.012 16.4 1.4 1 23 557 580 557 580 0.94
14 18 0.93 65 4.7 0.3 2 23 587 608 586 608 0.89
15 18 0.024 1.7 9.7 1.9 2 23 614 635 613 635 0.97
16 18 2.4 1.7e+02 3.4 2.1 3 23 643 665 641 665 0.90
17 18 0.0095 0.66 11.0 0.2 1 23 701 723 701 723 0.97
18 18 0.08 5.6 8.1 1.9 1 23 729 752 729 752 0.97

Sequence Information

Coding Sequence
ATGGAAGAAACAAAAGAAGATATTAAAATAAAAATAAAAATTGAAAGAAAAGACCCTACCTCATTCTTACCAGAGGAACCAATGAGCTATGAGATTAAAAAAAAGAAGAAAAAGAAAAAGAAACTTCAAGAGGACCCATTCAAAGATATAGATGATAAAATGGAAGTAAAGACAATTGTGACAGAAATTGTTCCAGCCTCCTTGGATCCTGAAGTCAGTATAAAAGCTGAGAATATTGAAGTGGAACTGGACTTTAATGATTTTACAGATAACCAAGGTCTGATGCTACAAACTCCACACAGTGACGATAGCCAAGAACCCGCAATTAAATACGAAAATCAGAATCACCAGGCCGTTATACTTACCTTTGAGAGCATCATCAACGAGAACAAATTATTAGCGCCGCCCATTTCTGAAGAATTGGACGTTACACCGAAACCAGAACACTTCTGCAAAATATGCCACCTAGTTTTCCAATCTACTAAAACTTTAAGAATGCACCAGAAAAGGAAGCACAAGGTTTTCAGAAAGGCTTTCAAAAATAGATGTGATTATTGCGGCATGGCTTACGAAAACAAAAACAGTTTAGCGGCTCATATTAAGAGGAAACACGGACCAAATGCTCCACCAGATGATAAGGAAGAAAGGACTTGTGACATTTGTGCTCTAGTGTTTAAAGGAATGGCCAGGCTACGTATGCACATGAGAAGGAAACACGGATCATTCCAAGATTCTTTTAAGCACGTTTGTGATGATTGCGGTTTGACTTACGATAAGTATAGAAGCTTATTAGTACATATACAACGGAAACATTCGAATCAAACAAAACCAGAGATCAGTCAGTGGTATAACTGTATGTTTTGTTCGAAAATGTTCACAAAAAGAGAAACGTACGCAAGACACGTGCAAAGAAAACATCAAGTTGCTGAAGATAATATCAAGGATGAAAATGCGGAGTATGATTTAGAAAATTGTAAAAATGAGCAAACCGGTGAAATAACTTGCAAGGAATGTCCTCTAGTCTTTTCGTCTTTGAATTTCTTGAAACTACACATGAGGAGAAAACATAACGCATTGCGAGATGATTTTAGGTTGAAGTGTAGGATTTGTAACTTGTCTTACGATAAGATTGAGAGTCTGAAACGTCATGTGAGAAGAAAACACGATAAAGGATCGCATTGTGAGGTGTGTAACAAGCAATTTGATACCAGGGAAATGTATTTAAATCATTCTCATACAAAAGTTATAAAAGAATGCTCAATTTGCGGACTCATATTCGCCTCTCAAGGCGGTTTGGCGAAACATCTAAGGTGTACACACAAAATAGATACACCAAAAACAATTTTCTGTAATTTATGCAATGAAGGTTTCCATGATAAGCGTCAATTGAAACCGCATTTCATGAAAGTGCATTTAAAAGTTTCTTATACATGCAGGTACTGCAAAAAAGTGTTTAAAGCGAAAGAAAGTTATCGCCGGCATATCTTGTTCAAGCATCCTACTTCCGAACATGTAAACACTCAGTTACAAAAATGTGAGAGTTGCAACGAAATGTTTAAAGATGAGTTTGAGTTATGTAAGCACATAAACTTAGCTCACGGACAAGGAGACGAAAATATGTTGATTAAAACGGTGATTAAAAGGGAAGATGATGATGTTAAGACCCGTTTTCAGTGTACAAAATGTCCAGAAGTTTATATTACATGGGAGCAATTAAAATTGCATTACGAACAATGCCACTATAATGTAGAACATACTCAATGCCAGATATGTGGTGAGATTTTACCAGGCAACGAGTTACAGAAGCATATTAAAAACCAACACACTGACACCGATATGAAGTGCAAGTATTGTGAGTTCAAAACGAACATAAAAATAAGTTTAACCCAGCATATGTTGAGGCATAAAAACGCTGCCACATTACACTGTGACTACTCGGGTTGTAAATATAAGACGTTTTATGAAGGTGCTATGGAGAAACATAGAAGGAAGCATGCCGATCAAGGAGTCAAACTCCAGTGTACGCAATGTCCGTTCCAATCTATGAATAAATATATATTAAAATATCATGAGGAAGCCCATGAAACAGGTGTTAAAAGATATACGTGTGATCAATGTGATTATGCAACGATTTTACCAGCGAATTTGGTTCAGCATAAATATAAACATTCAACCGAAAAGAGGTTCAAATGTGAAGTCTGTCCTTTTGCAACGAAGTACAACACTTCTTTACGTTTTCATGTAAGGAAAAAGCACTGTGATCTCCCAACATTCAGCTAA
Protein Sequence
MEETKEDIKIKIKIERKDPTSFLPEEPMSYEIKKKKKKKKKLQEDPFKDIDDKMEVKTIVTEIVPASLDPEVSIKAENIEVELDFNDFTDNQGLMLQTPHSDDSQEPAIKYENQNHQAVILTFESIINENKLLAPPISEELDVTPKPEHFCKICHLVFQSTKTLRMHQKRKHKVFRKAFKNRCDYCGMAYENKNSLAAHIKRKHGPNAPPDDKEERTCDICALVFKGMARLRMHMRRKHGSFQDSFKHVCDDCGLTYDKYRSLLVHIQRKHSNQTKPEISQWYNCMFCSKMFTKRETYARHVQRKHQVAEDNIKDENAEYDLENCKNEQTGEITCKECPLVFSSLNFLKLHMRRKHNALRDDFRLKCRICNLSYDKIESLKRHVRRKHDKGSHCEVCNKQFDTREMYLNHSHTKVIKECSICGLIFASQGGLAKHLRCTHKIDTPKTIFCNLCNEGFHDKRQLKPHFMKVHLKVSYTCRYCKKVFKAKESYRRHILFKHPTSEHVNTQLQKCESCNEMFKDEFELCKHINLAHGQGDENMLIKTVIKREDDDVKTRFQCTKCPEVYITWEQLKLHYEQCHYNVEHTQCQICGEILPGNELQKHIKNQHTDTDMKCKYCEFKTNIKISLTQHMLRHKNAATLHCDYSGCKYKTFYEGAMEKHRRKHADQGVKLQCTQCPFQSMNKYILKYHEEAHETGVKRYTCDQCDYATILPANLVQHKYKHSTEKRFKCEVCPFATKYNTSLRFHVRKKHCDLPTFS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00932998;
90% Identity
-
80% Identity
-