Lfle003516.1
Basic Information
- Insect
- Laspeyria flexula
- Gene Symbol
- -
- Assembly
- GCA_905147015.1
- Location
- LR989950.1:10025302-10033925[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.00075 0.052 14.4 0.2 2 23 144 166 143 166 0.95 2 12 1.3 87 4.3 0.3 6 23 176 193 174 193 0.92 3 12 0.0066 0.46 11.5 2.5 1 19 226 244 226 249 0.94 4 12 4.6 3.2e+02 2.5 0.4 6 23 259 276 257 276 0.94 5 12 0.0012 0.081 13.8 0.3 3 23 284 304 282 304 0.96 6 12 8e-05 0.0056 17.5 2.5 1 23 312 334 312 334 0.97 7 12 0.0012 0.083 13.8 2.3 1 23 343 366 343 366 0.97 8 12 0.00021 0.015 16.2 0.2 1 23 372 394 372 394 0.97 9 12 1e-06 7.1e-05 23.5 2.0 1 23 400 422 400 422 0.98 10 12 0.00037 0.025 15.4 1.0 1 23 427 449 427 449 0.98 11 12 2.8e-06 0.0002 22.1 4.2 1 23 455 477 455 477 0.97 12 12 2.5e-05 0.0017 19.1 0.6 2 23 484 506 483 506 0.95
Sequence Information
- Coding Sequence
- ATGGCTATGGATCTAAAAGAGTTGTGCAGATTATGTGCAAAAAAACACGAGTATTCGAGAGATATATTGGATGAAAGTAACAGAAATACACATAAACTTATACAGGATTTTCTACAAATAATTGTATATGAAAATGACAATTTACCAACTAAAATTTGCTTGAATTGTGAAGAAAAAATGGTCTCATTTCAACTATTTGTGCTTGAGTGCTATAAGGTTCAAGAAACACTGAAAAAGATGTATGAAGAGGAGATACCAATTACCGATTTAAAACTTGACTTAAGGCTTCCTTTAGATTGTGCAGTACCAATTAAATCTGAGGTAAAAGATGAAGTTACTGCAGAAGATATCGTTTCCGCACTGAATGATGACCCAACACTGGCAGTGATAGATAAATCTAATCTGAAAGTTAAGGATTTTGTAAAATTACAATGCAATTTTTGTGAAGAAAGACTAAAAACATGGAGTGGATTACGGGCACATTATGCAAAGGAACACAAAAGTAAACCATATGTTTTTTGTTTGTGTGGTTTTGTTGTACGATCTAAGAGTGTTCTATACAAACATGTCTCAGACCATAAGTTAGAGAGTAGAAAATTAAAAAAGAATTCCGAAACAGATGATGAGAAGCAAGATGTTAAATATTCAAGTCTAAATGTGAAAGATTTTATAAGGTTCAACTGTCCTCGATGTGATGAAGAATGTTCAAGCTGGTATAGTCTGAAGGCTCATTGCGAAGAAGTTCACAATATAATGCCTGTAGTGTCCTGTAGCTGTGGTATTACTCTAAAGTCTAAATCTGTTATGTATAAACATGTACAGGATCATAGAAACCCCAATGTATTAGCTTGCGATAAGTGTCCCCGTATAACGAAGACTTTGGCAGCCTTGAATAAACACAAGATGAGACACATACCGAAATCTGAAAGGAAATTCTGCTGTGGTTCTTGCGACAAAATTTTTACTTCCAAAGACGCTTTAAAATCACACGAAAAATCGCATATACCAATAGAAGAACGAAAGATATATCACTGTGAAACGTGCAATATGAAGTTTACAACACGATCGTCGGCGGCTTCCCACAAGCGTGTGGTGCACGACAAGATAAAGGGCTACGTGTGCGACCTGTGCGGGTACGCGTGCGGCACCAACGGAGAGTTGCGGCAACACCGCGCCATACACAGCGACGAGAAACCCTTTGTTTGCTTGAAATGTTCTAAGCCATTTAAGACATATTCTAACCTGAAGACGCACATGGACACGCACGAGGAGACCTCGTACGAGTGTTACATCTGCAGGCGCGTGCTCAACAGTCGCCGCACGCTACGGAAACATCTACTAGTACACGAGGACAAGTGCAGGCATGTCTGCTCCTACTGCAACAAGGCCTTCAAAAGGAGACAGACACTCAAGGTGCACATGTATACGCACACGGGCGACAAGCCGCTGACGTGCAAGTGGTGCGACGAGCGCTTCTCGTACGCGTCCACGCTGCGCTCGCACCGCCTGCGCGCGCACCCCGACAAGGTGTCGCTGCAACACAACGTGTACTCGTCCTACACGCACGTCGCCATGTCGCAGGACTATATTAAAGAAGATTTGGCAGCCGTGAATGTACCTGTAGCAAAGAACGAAGTTGAGGCTATGTAA
- Protein Sequence
- MAMDLKELCRLCAKKHEYSRDILDESNRNTHKLIQDFLQIIVYENDNLPTKICLNCEEKMVSFQLFVLECYKVQETLKKMYEEEIPITDLKLDLRLPLDCAVPIKSEVKDEVTAEDIVSALNDDPTLAVIDKSNLKVKDFVKLQCNFCEERLKTWSGLRAHYAKEHKSKPYVFCLCGFVVRSKSVLYKHVSDHKLESRKLKKNSETDDEKQDVKYSSLNVKDFIRFNCPRCDEECSSWYSLKAHCEEVHNIMPVVSCSCGITLKSKSVMYKHVQDHRNPNVLACDKCPRITKTLAALNKHKMRHIPKSERKFCCGSCDKIFTSKDALKSHEKSHIPIEERKIYHCETCNMKFTTRSSAASHKRVVHDKIKGYVCDLCGYACGTNGELRQHRAIHSDEKPFVCLKCSKPFKTYSNLKTHMDTHEETSYECYICRRVLNSRRTLRKHLLVHEDKCRHVCSYCNKAFKRRQTLKVHMYTHTGDKPLTCKWCDERFSYASTLRSHRLRAHPDKVSLQHNVYSSYTHVAMSQDYIKEDLAAVNVPVAKNEVEAM
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -