Lfle021769.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Laspeyria flexula
Gene Symbol
-
Assembly
GCA_905147015.1
Location
LR989951.1:15920210-15932354[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.74 51 5.0 0.4 2 23 266 287 266 287 0.80
2 11 0.00046 0.032 15.1 2.0 1 22 292 313 292 316 0.92
3 11 0.00091 0.063 14.2 3.7 2 23 442 464 441 464 0.94
4 11 0.0038 0.26 12.2 0.0 1 23 470 492 470 492 0.96
5 11 0.029 2 9.5 0.2 1 23 503 526 503 526 0.88
6 11 2.3e-07 1.6e-05 25.5 3.5 1 23 531 553 531 553 0.98
7 11 1.4e-05 0.00096 19.9 1.6 1 23 559 581 559 581 0.98
8 11 0.00011 0.0075 17.1 4.9 1 23 587 609 587 609 0.98
9 11 4e-08 2.8e-06 27.9 1.0 1 23 615 637 615 637 0.99
10 11 0.00024 0.016 16.0 0.1 2 23 680 701 679 701 0.97
11 11 0.0066 0.45 11.5 4.9 1 23 707 730 707 730 0.95

Sequence Information

Coding Sequence
ATGGAAGTATACCTTTACAATTCCACTGTTTGTAGATTATGTGGTGAAGAAAACGATAATGGAACCTTTTTATATTCTTGTGAAGAAAATAACACAAACTTAAGCGAAGTTATAAATACATATTTACCACTCAAGGTGTGTGATGATGGACAGCTGCCTCGAACCATATGTCCAGGATGCACTATTCAATTGGAGGCCGCCGTAGAATTTTTAACTTTAATTATAAATGGACAGAAAATAATTCGTGAACTGCATCTTAGAGAAAGGGAATATAAAAAGACCATTCTGAGTCCTGCTCCGGAACAAGATGTTATTACTGAAAAGATTGTCTACGAAGTAAATACCAGTAATGGAGTATACCAAGTTGAACATCCGATTGCCTTACAAGTAGCTGGTCTTGATAAACCTAAACGTAAGCGAGGCAGACCTCCGAAGAAGCTTAAAACTCCTGAACAACTAGCACAGGAGGCGGCTGCCAAAGAAAAAGAGCAGAAATCAGCCAAAAGACATGAGAGAGATGATGAGCCAACTGGAAAACGGAGAAGAAAAACTCCAACAAGGTTCAGAGAAGCTGTGCAGGGCAAAGAACTAGATAGAATATTCAAAGAAGAAGGTGTGACTGATGGAGAGGAAAGTGATCGTGATGTAAGACCCAGTCCTGGGATGGATGTCAAGCTTCCTGTGTCAAAAGAACCAGAAATCATTGGGCATATGGAGAACTCCGGTGAACTTGTAGTCTTCGTGAAGGGCAAAGGACGTGGCAGACCCAAAGGGCCAATGCGGTTAACTCGCAGAGAATGCACAATCTGTGGAATGGCGTTCTCTTGTGCTGGCCGCTACATGTCTCACGTGGCACAACATGGCCCTGTCATGTACCAGTGCCAAGAATGTAATGAGACCTTCGATACACACATCAACTTCGCTAACCATCAGAAACAGCTCAGCCATAGTGGAAAGAATATTATTCAGATTAGCAAGAAGGCTGCTCAAAAACTTCAGCATGCACAGGAAGCAGCAAAGCTAGACCAGGATACCCTGAGTCAACCATCAACAGCGGAGACCCCTGAAGTAGGAGAGAACACGTTAATTGAGAATGTTGTGATGACATCGCTGCCTGACTTGAATGCACAGCCGGTCCCTAGTCAACCTGAGGCTGATGTTCTACTCGCACCTGCCACTCCTACCGTTGAGTTTGTATCATGCTCTTCTATTGATGGTGCTGTAACAATAACAGACATGCCTACAAATGTGGTTGAAGAAGTTACTGAGAAGCCAACGGAAGAAGTTGTAAAGGAACCGGCACCTACTGGGAAACCGAGATTGAAGTGCAACCATTGTGATAAAACGTTTAGTAGTAAACAGAGCAAGTCGCTACATATTAAGGCGACGCACTCGGGCGAGCGGCCGTACGTGTGCGTGGAGTGCGGCGCGCGCTTCGCGTACCCGCGCTCGCTGGCGCTGCACGGCATCTCGCACCGCCGACACCGACCCAACCACGCCAAGGGGTTCGCCTGCGACCTGTGCGGGAAGGTCCTTAACCACCCATCATCAGTAGTGTACCACAAGGAAGCGGAACACGCGGGTCAACGATACGTGTGCAACAAATGTGGCAAGTCTTTCAAACACAAACAGTTGCTGCAACGTCATCAACTTGTTCACTCGCAAGTCAGACCTTATACTTGTAAGACATGCGACTCCTCGTTCAAGACCAAAGCGAACTTACTGAATCATCAGTTGTTACACACGGGTGTTAAGAAGTTTTCCTGTGAGATATGCAAGCACAAGTTCGCGCACAAGACTAGTCTCACGCTACACATGAGGTGGCATACGGGTCAGAAGCCGTACACGTGCACCACGTGCGGCAAGAGCTTCAGTCAGAAGGGCAACCTGTCGGAGCACCTGCGCATCCACACCGGCGAGAAACCCTTCCACACCGGCTGCACGCGCGCCGCCACGCCGCGCCCCCGCGCCGCCTGTCCCGCTCGGCGCGGCCCGCGCCCCGCGCGCCCCCCCCGCCCCGCGGGGCGCGCCCCGCAGCGCTGCGCGGTGTGCGCGCGCGTGTTCCCGGAGCGCGCGGCGCTGCTGAAGCACATGCGCACGCACGCGGCGGAGCGCGCGCACCGCTGCCCGCACTGCCCCCGCGCCTTCCTAGACTGCGCCAATCTCAACAAGCACAAGAAGCAAGTCCACAAACCGATGAGCCTACTAGCGAACTCCCAGCCGCATCAGCCGCTGCCAGCCGCCTCCACAATCCTCCCCAAGCTGTCCCCCGGGATATGTGTGGAGGAAACTCAGGACGACTCGCTAGAGGAGCGCGTCATATACGTCGCGTACGATGTGGACGAGCCTGACTCACCGGCCTTCCATATACTCTCACCAGAACAGTCGGCAGGTCTCGACGATGGCAAAATGCTGACAAGTTGCGAGCTATACTCGGGACCGTCACTGCTAGTGCCACAGCCTGAACTAGAACAGCTGGAACAATTTGAACAAGAAGAGTTGGAACACCTTGTGTTGGATGGCCATCATGAGCATATGCCGGTGACAGACGAACAAGGGAATCCACTACACTTCACGATGCAAGATGGCACCAGACTTGCTATCACCTCTGCAGATGGTAAATCTTTACAGGTGATCACTCAAGATGGCCAGACCATTCCTGTTGAGATAAATGGATTTGCTGAAGAAGAGGAGGTGTCTAACCCAGACACGATAGTTCATCAGCTTAACATACAAAAGAGTGTAGAGCAAGAGGCGTCTGCGCCGGTCACACATTACTTTACCATAGTTTAA
Protein Sequence
MEVYLYNSTVCRLCGEENDNGTFLYSCEENNTNLSEVINTYLPLKVCDDGQLPRTICPGCTIQLEAAVEFLTLIINGQKIIRELHLREREYKKTILSPAPEQDVITEKIVYEVNTSNGVYQVEHPIALQVAGLDKPKRKRGRPPKKLKTPEQLAQEAAAKEKEQKSAKRHERDDEPTGKRRRKTPTRFREAVQGKELDRIFKEEGVTDGEESDRDVRPSPGMDVKLPVSKEPEIIGHMENSGELVVFVKGKGRGRPKGPMRLTRRECTICGMAFSCAGRYMSHVAQHGPVMYQCQECNETFDTHINFANHQKQLSHSGKNIIQISKKAAQKLQHAQEAAKLDQDTLSQPSTAETPEVGENTLIENVVMTSLPDLNAQPVPSQPEADVLLAPATPTVEFVSCSSIDGAVTITDMPTNVVEEVTEKPTEEVVKEPAPTGKPRLKCNHCDKTFSSKQSKSLHIKATHSGERPYVCVECGARFAYPRSLALHGISHRRHRPNHAKGFACDLCGKVLNHPSSVVYHKEAEHAGQRYVCNKCGKSFKHKQLLQRHQLVHSQVRPYTCKTCDSSFKTKANLLNHQLLHTGVKKFSCEICKHKFAHKTSLTLHMRWHTGQKPYTCTTCGKSFSQKGNLSEHLRIHTGEKPFHTGCTRAATPRPRAACPARRGPRPARPPRPAGRAPQRCAVCARVFPERAALLKHMRTHAAERAHRCPHCPRAFLDCANLNKHKKQVHKPMSLLANSQPHQPLPAASTILPKLSPGICVEETQDDSLEERVIYVAYDVDEPDSPAFHILSPEQSAGLDDGKMLTSCELYSGPSLLVPQPELEQLEQFEQEELEHLVLDGHHEHMPVTDEQGNPLHFTMQDGTRLAITSADGKSLQVITQDGQTIPVEINGFAEEEEVSNPDTIVHQLNIQKSVEQEASAPVTHYFTIV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-