Basic Information

Insect: Lasioglossum vierecki
Gene Symbol: topi
Assembly: GCA_028455595.1
Location: CM052344.1:6587780-6595911[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 1.8 1.5e+02 3.3 3.2 1 23 195 217 195 217 0.88

2 15 0.018 1.5 9.6 1.3 2 23 224 246 223 246 0.96

3 15 0.0019 0.16 12.7 0.4 2 21 253 272 252 273 0.92

4 15 0.00048 0.04 14.6 2.4 1 23 280 302 280 302 0.97

5 15 1.5e-07 1.2e-05 25.6 0.9 1 23 308 330 308 330 0.97

6 15 0.13 10 7.0 3.8 1 23 379 401 379 401 0.96

7 15 2.9 2.4e+02 2.7 0.2 1 23 407 429 407 429 0.73

8 15 0.025 2.1 9.2 0.8 1 23 439 462 439 462 0.94

9 15 0.032 2.7 8.8 0.0 1 20 476 495 476 497 0.93

10 15 0.0047 0.4 11.4 0.1 1 23 502 524 502 524 0.98

11 15 2.1e-06 0.00018 22.0 3.1 1 23 530 552 530 552 0.98

12 15 0.00014 0.011 16.3 0.4 1 23 558 581 558 581 0.97

13 15 0.051 4.3 8.2 0.7 1 23 587 609 587 609 0.89

14 15 3.4e-07 2.8e-05 24.5 2.2 1 23 615 637 615 637 0.99

15 15 8.1e-06 0.00068 20.1 5.2 1 23 643 666 643 666 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	1.8	1.5e+02	3.3	3.2	1	23	195	217	195	217	0.88
2	15	0.018	1.5	9.6	1.3	2	23	224	246	223	246	0.96
3	15	0.0019	0.16	12.7	0.4	2	21	253	272	252	273	0.92
4	15	0.00048	0.04	14.6	2.4	1	23	280	302	280	302	0.97
5	15	1.5e-07	1.2e-05	25.6	0.9	1	23	308	330	308	330	0.97
6	15	0.13	10	7.0	3.8	1	23	379	401	379	401	0.96
7	15	2.9	2.4e+02	2.7	0.2	1	23	407	429	407	429	0.73
8	15	0.025	2.1	9.2	0.8	1	23	439	462	439	462	0.94
9	15	0.032	2.7	8.8	0.0	1	20	476	495	476	497	0.93
10	15	0.0047	0.4	11.4	0.1	1	23	502	524	502	524	0.98
11	15	2.1e-06	0.00018	22.0	3.1	1	23	530	552	530	552	0.98
12	15	0.00014	0.011	16.3	0.4	1	23	558	581	558	581	0.97
13	15	0.051	4.3	8.2	0.7	1	23	587	609	587	609	0.89
14	15	3.4e-07	2.8e-05	24.5	2.2	1	23	615	637	615	637	0.99
15	15	8.1e-06	0.00068	20.1	5.2	1	23	643	666	643	666	0.96

Sequence Information

Coding Sequence: ATGGACAGCGACTGGCTGATCAATCCACCGACTCGTCTCATTTCTATTTGCCTAGAGTTTGGAGAGTCTTTAAGACTTTTGGACAAGATAAACACATGTTTAAGCATTAAGGTGAAGAAAACAGATCCTCTTCCGAAACAACTTTGTCCAACGTGTGTCGAAAAGATTACTTGGTGTAACGACTTTGATTCTCAATGTATCAGAGCCGAGGAGACTCTTATAGAAATTCTCAAGCAGAAACATTCTTTTGTAACTATTAAGACTGATGCAAACCATTCAGAGAACAATGATTCATGTCCGTTATGCATCGAAGGACGAATGAAGATCTACGAAGAAGCTAAGAGTGATCAAAAGGACATCGACTTGTATGACAGTGACATTGTTCTTGAGAGCAGCGACGAAGAACAAATTCCAAGTGAACTTAGAGCTGACGAAGAAGCTGAAAGCGGAGCCATTACACTGTTTTGTTTGGGAACCAAGCAAAAATATTTGAAATGTGGTGCTTGTATGAACCTTTATCATACAAAGGAAACTCTAGATGAACATAAATGTAAACCAAACTTGCAGTGCACATCCAAGCCTTATAAGTGTGATATCTGTCTCGCAACGTTCACCTTCGAAGAGCGATTGCGATTCCACCAACATTTTCACAAGGAAGCAAAAGCATTGTATTGCGAAATTTGCAAGATTACTTTTGGGAAGGAGCAAAAGTTATTTTATCACTACAAGAGGTACCATTGCAAAGATGGCAGAGTATCCTGTTTGCAGTGTGGAAAATTATTTGAAAATCAAGAAGGGCTAAAGAAACACGTCTGTGTGGATGGTAAAACAAGACCTCATGTGTGCGAGGTCTGTTCTAAAGGATTCTGCGATGGGTATACtttgaagcgtcacgtggtgacccatctcccagagaagccgtacaaatgtcccgaatgctcaaaaagcttcacacagaagtcaagattaaataaacacatAGCTGGCCACAGTATCGTTTTAGAAAACAGTCAAACAATTTGGAGGTGTGTTCGTTGCGGCGAAGTGTTTGGGTCATGCGAGACCGCAGACGAGCATTGCAAGATGCACGAAGAGAACGTAAGTCTCATCGAAGAGTTGCAGGCGTTGAAGCTTTACCACTGCGAGTTCTGCAACAGCCACTTTGCAGACATGAACTATCTAAAAGCCCACCGCGATTTACACATAGTTGAAAAACCATACTCGTGCAACGAGTGCAACTCGTGGTTCAAGTCTTTCGCAGAGGCTGTCCTTCATTGGAAGGAGCATCCGAGGATATTCAAAGTCTTGGTAGTGTTCTTGTGCGATGTTTGCGATAGGGACGTTAAAGAATTGTCTCTGCTCTACAAGCATAAACAAAAGAGGCATCAGCCGGTGGCTAGAAAATCGGAGAAGAGCGAAGAGAAGTTTATTTGCGAACTTTGCGGAAGCATTTTTGTGAGCGCTGAAGACTTCCAAGAACACGGGAAGTACAGATGCTCTAAATTCCCCTGTGACATTTGTGGGAGTTTGCTGCCCACTGCGAATTCTTTGAACGCGCATAAAAGAAGACACAGTGGACTCAGGCCAtacgtttgcaatatatgtggcaagagttacacgcagtcgagtcacatgtggactcacaaaaggttccatatgggcgtcaaaccttacgcgtgcgagtattgtgatcagagatttactataaaacctgacctagcggatcatactagaaagaagcatactagagagagaccatttaagtgcgacgtctgcaacaaagctttcttaacgggttccgttttctatcaacatagattaatacacaggggagatcgcagatacaagtgccactattgcgagaaagcattcaccagaacagaagctttgaataatcacattaagattcataccggcgagaaaccacacgcgtgtgacgtttgtgggagatgtttcaggcaaaaaggggacatgagaaagcacaggcgtacgcggcatactgctaagCAGGACTTGAAATAA
Protein Sequence: MDSDWLINPPTRLISICLEFGESLRLLDKINTCLSIKVKKTDPLPKQLCPTCVEKITWCNDFDSQCIRAEETLIEILKQKHSFVTIKTDANHSENNDSCPLCIEGRMKIYEEAKSDQKDIDLYDSDIVLESSDEEQIPSELRADEEAESGAITLFCLGTKQKYLKCGACMNLYHTKETLDEHKCKPNLQCTSKPYKCDICLATFTFEERLRFHQHFHKEAKALYCEICKITFGKEQKLFYHYKRYHCKDGRVSCLQCGKLFENQEGLKKHVCVDGKTRPHVCEVCSKGFCDGYTLKRHVVTHLPEKPYKCPECSKSFTQKSRLNKHIAGHSIVLENSQTIWRCVRCGEVFGSCETADEHCKMHEENVSLIEELQALKLYHCEFCNSHFADMNYLKAHRDLHIVEKPYSCNECNSWFKSFAEAVLHWKEHPRIFKVLVVFLCDVCDRDVKELSLLYKHKQKRHQPVARKSEKSEEKFICELCGSIFVSAEDFQEHGKYRCSKFPCDICGSLLPTANSLNAHKRRHSGLRPYVCNICGKSYTQSSHMWTHKRFHMGVKPYACEYCDQRFTIKPDLADHTRKKHTRERPFKCDVCNKAFLTGSVFYQHRLIHRGDRRYKCHYCEKAFTRTEALNNHIKIHTGEKPHACDVCGRCFRQKGDMRKHRRTRHTAKQDLK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00085636;
90% Identity: iTF_00862754;
80% Identity: -