Lpau016401.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Lasioglossum pauxillum
Gene Symbol
ZFHX3
Assembly
GCA_028455745.1
Location
CM052305.1:17020950-17034646[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.23 25 6.1 0.1 2 23 224 246 223 246 0.91
2 16 0.00018 0.02 15.9 1.8 2 23 469 491 468 491 0.95
3 16 4.4e-05 0.0049 17.8 0.7 1 23 523 547 523 547 0.92
4 16 0.0064 0.72 10.9 0.4 1 22 604 625 604 628 0.91
5 16 6.1 6.9e+02 1.6 0.8 2 20 853 871 852 876 0.88
6 16 3.1 3.5e+02 2.5 1.5 1 23 900 924 900 924 0.91
7 16 0.075 8.4 7.6 0.1 2 23 1017 1039 1016 1039 0.95
8 16 0.086 9.6 7.4 0.1 3 23 1060 1081 1059 1081 0.95
9 16 0.0017 0.19 12.8 3.5 2 23 1145 1167 1144 1167 0.95
10 16 0.0032 0.36 11.9 1.3 1 23 1184 1206 1184 1206 0.97
11 16 0.00015 0.017 16.0 0.4 2 23 1213 1235 1212 1235 0.95
12 16 0.0015 0.17 12.9 3.6 1 23 1325 1349 1325 1349 0.91
13 16 0.0051 0.57 11.3 0.6 1 22 1369 1390 1369 1393 0.89
14 16 0.00069 0.077 14.0 0.2 1 23 1434 1458 1434 1458 0.93
15 16 0.079 8.9 7.5 0.1 2 21 1505 1524 1504 1525 0.94
16 16 0.15 17 6.6 2.0 2 19 1670 1687 1669 1692 0.91

Sequence Information

Coding Sequence
ATGCCCTCCAcaaaagcaGGAGATGAGCCCGGAGGAGGAGGGGGGTCGAGGGGGCGGGTCCCCCCCCCGGCAGCGGGGGCTGCGCTGCACCAGCCCCACCACCCCCGCACGGCCAGTCCACCCTCCGGCACGGAACCCTGCACCCGCGATGCCATACCAACGCCTACACCGATCGCGGACACTACCACGACCACTACCACGACTACTATGACCATGCAATCGCAAGGGCAGCAACAGCAAGAGCAGCAAGGTCCCAGCCCGAGCCCAAGTCCAACGGGCGGCGACGTTGAGAAATTCGATGGGAAGATCGTCTACAACCCGGACGGTTCGGCGTACATAATCGAGGGCGAGAGCGAACTGAGCGAGGACGACTCCCTGCCGGATGGTTGCATCGTAGACGGTCGCGGTGTCTCTGTTCCTCATTCTTTAGTATTTCCTCAAATCGCGAGCGCGTACTACGTGTCAAGACTGTACGCCCATCAGGCCTACCAACAGCAGCAGCAACAGCAACAGCAACGCTCGGCGGTCCAGCAGCACAATCCCGATCTTCCTGTAATGCACAGCTATCGGGTAATTAGCTACAGAAGCGCGGAGGGTAGCAAACAACCGCCTCCGCCCCCGACGGCGCCTCCACCGCCTGCAGCATCGGTGCCCGTGAAACCTATTTTGATGTGTTTCATATGCAAATTGAGCTTCGGGTACGCGAAGAGCTTCGTGGCGCACGCCCAGGGTGAACATCAGCTCACCCTGATGGAAGACGAGAGGCAAGTGCTTTCTCATTCGACGGCGTCGGCGATCATCCAGGCCGTGGGCAGGGGAAAACAGCCGCTCGTCAGCTTCCTCGAGCCCGTGACAAATTCCACGTGCCCGCAATCGTCGCCCGCGCAGATGCCGAGCCAACAGCAACAGCAGCGCGCCGAATCGAACGAGCACGAAACACCGACGGCGACTAGCACGCCGGCCAGCACGCCCGGAGTCCCTAGCAGTCCTCAACAACAGCAACAGCAGCAGCAACAGAGGCCATCGCCGAGCACACCCACCACACCCACGTCTCATTCGAATCATCCTCTATCGTACAATCATCAACAGCCACAGCAACATCAATGGACCGGGGCGCAGGTGAGCGCTGCCTCCTGGGCCAAAGCACCGGACGCCATGCATTACACTTCACCACCGCCACCGACTTCGTCGACCAAAGGCTCGCCGTCTTCTTACGCTGCGCTGACGCAGCAACCACCGAATTTCCTAACGGGCACCACCATCGGCGTGTGTCCCGAACACATGCAGGGCAGGCCGAGCGGCGTCGAGTGCCCGAAATGCGAACTTATCCTCGCCAGTAGCCGATTAGCGGGTCCGGGTGGACCGTTGGCAGGTATTCACAGTCGAAACTCGTGCAAAACGTTGAAGTGTCCGAAATGTAATTGGCATTACAAGTACCAGGAGACCTTGGAGATACACATGAAGGAGAAGCATCCGGAGAGCGAGACTTCCTGCATCTATTGCATCGCTGGCCAGCCTCATCCTAGGTTAGCGCGGGGCGAGACGTACACTTGCGGGTACAAGCCGTATAGGTGCGAGGTGTGTAATTATTCGACCACGACGAAGGGTAATCTCAGCATTCACATGCAGAGCGACAAGCATTTGAATAACATGCAAGAGCTGCAGCAGGGCGGAGGCGGCAGTTCGGGCGCCAGCAATCCATCCTCCTCGCAAGACGCGCCGATGCCTACGAGAAGTCCGCACCATCAACAGAACCATAGTCCGCACATCGCTGGCCAAGCCGGAAACCAAAGTAAACCGAAGCCGACGTTTCGCTGCGACGTCTGCAACTACGAGACCAACGTGGCGCGCAACCTGAGGATACACATGACCAGTGAGAAGCATACGCACAACATGCTGGTCCTGCAACAGAACGTGAAACACATGCAGACCTTGTCCGCGTTgcagtcgcatcaccagcaagcacagcatcatcatcaacaagcgcaacagcaacaccaacagcaactcgagcagttgctccacctgggcGGCTTGGACAAACCCCAACATGCCGAAGCGGCTCTCGCAGACATGGCTTACAATCAGGCCCTATTGATTCAAATGATGACCGGTGGTCAGCTGCCACCGCAGCTCCCACCGGAAATTATGGGCGGCATGGCGAGTATGGGCGCGATGGGAAATCTTGGTGGGGACGTTGGACTTTCACCAGACAGTATGGATCCTCCTCCGGAACCGGCTGATCCCGACCCGTCCCATCTCTATCAATGCTGCGTCTGCAACAATTTCGCGACCGACTCGCTCGAGGCCCTGACCCACCATCTGGCTGTGGACAGAACGCGGACACGCGAAGGCGAGATCCTCGCCCTGGTAGCCGGCCACTTCGTCTGCAAACTTTGTTCCTATAAAACTAATTTAAAAGCGAACTTTCAACTACACTGCAAAACGGACAAGCATCTGCAACGCCTGCAGCACGTGAACCACGTGAAGGAAGGCGGTCCGAGGAACGAATGGAAGCTGAAGTACTTGGCCTCACCCACCAGCGCCGCGCAATTGCGTTGTCACGCGTGCGACTATTACACTAACAGCGCTCATAAACTAGCCCTACACGCTGCCTCCCCGAGACACGAGGCCGCCGCGCTCCTTCTTCGTCATCTGCTCGAGGCTAGTGCCAACGTGCCCACGCAGGGCAAACTTTATCATTGCGCCCTATGCGGGTTCAGCGCGAGGCACAGACTGCCGCTTCTGCAGCACGTCCGATCCCTCAGACACCTGCAGATGGAGCAACTGCATCAGCTCCATCGGCGGAGCGGCATCCAAGGCAACGAAACTCCGCACACTGACATCGGTGACGTTTTTCAAGTCGTCGGCGATCCTGATGCACCACCCGCGCAACAATCCAGTCCGACTACACCCACCACTCCCAACGCCACCAGTGTTAACAGTGAACGACGGGAGGATGGTAGCGACTGCGGTAACGAGGTAAAGCAAGAGCCGGACAACGATCAGGAAACGGAACAGGAACCGGACAACGATCACGAGGACGTCTCATGTCCGTATTGCACGTATCAGCCGACGTCTCGCGAGGAGTTGCGGCAGCATTTGCAGGTGGCTCATGTTCAGGACTCTGACGAGAAAACGGAGACGGTGAAGGAAGAACCACCGCCGGATTTGCTATGCCCGTTGTGTCAAGATGGCTTCCGGGAGCGTTCCGCTCTCGAGAAGCACGTGATGCAGATCCACTCGGTGAACGCGGACGGTCTGCAACGGCTGCTGCTGTTGGTCGATCAGAGTCATTGGCTGAACAACAACCCGAGGAACACGTCGACGCCAGCGGTGACAACGCCAACGTCGCCGACGACCACCACGAAGCCGCCGCAAGAGGACGACATCAACGAGCGGAGCGGTAACGATGAGATCGAGGAGATCACACGGTGCACCATTTGCGGGCGAATCTGCCGCTCCCTGGAAGAACTGCAGCAACATCATCGAGAGACTCATCCGGCTACCACGCCCACGTTGGCGGTCAGCGAGAAGCACGTGTACAAGTATCGGTGCGGCCAGTGCAGCCTCGCGTTCAAGACTCTGGAGAAACTGCAGCAACACTCGCAGTACCACGCGATTAGGGACGCGACCAAGTGCGCGCTGTGCGGCCGATCGTTTCGTTCCGTGCAGGCGCTTCAGAGACACCTGGAGTCGACGCACGCGGATTTGCACGAGGAGGAGTTGGCGCAGTACAAGCAGAGTTTGTTGCACGCCCATCCGCTTCTGCAGGCGCTCACCGAGGAGAGTTTCCGGAGGCAGGGGAATTTGAGCGGTGAGCAGAGCGTGGAAGACGACACCAGCAAGGCCGAGGAAGAGGAGAGCGACGCGAGCGACTCGTCGCCGTTGCACAAGGAACAACGTCTTCTGGAGGATTATCTGAACAGCCAGCCGGTCGCCGAAGACTCCTATCACGATCCCGGGAGGAAGTTTAAATGTCATCGTTGCAAGCTCGCGTTCACGCGGCAGAGCTACCTGACCGGACACAACAAGACGCTGTTGCACCGCAAGGGAGAGAAGATGTCCTATCCGATGGAGAAGTACTTGGACCCGAACAGACCGTACAAATGTGACGTGTGCAAAGAGAGCTTCACACAGAAGAATATACTGTTGGTTCATTATAACAGCGTGAGTCACCTGCATAAATTGAAGAGAGCCATGCAGGAGCAGGGTAACAACAACACGCTGATATCGGTCGTGCCGCCAGCCAGTCCCACAGAGTCGCCGGATTCGCAACAGGATCAAGATAAGAAGCCTTACAAGTGTAACATCTGTAAAGTGGCTTACTCGCAAGGCAGCACTTTGGACATTCATATGAGGAGCGTGCTGCATCAGACAAGAGCCAGCAAACTGCCAGATCTCGCTGCTAGTGGTCAATTAGACCTCGCGCGGCCGTTGATCGAGCAGCCGCCGCCATCCAGCCCGAACAGCCCACCTGTTAGCATGAACACCACCAGCACGGGAATGTTGTCTTGTCCGCGGTGCAGCGCTCTCTTTGTGAACCAGGAGCAGCTCGCCACGCATCAACAGCTCTATTGTATCTTCAGCAATCCGTTGGCATTGTTTCAACAATTGGCGGCGTCGCAGCAGCTCGTCCCGTCTACGCCGGCTAAAACACCGCCGCCGACGTCTACGACCCCGGGGCCGCAACAACACATGCAACAGAGCGTGCAACACGCCTCGCAGGCGACACAGGACATCCTGTCGCAGCCGCGTCACAAAACATCGCAGATGTACAAGCATCTGTTGGAGAGCTTCGGGTTCGACCTTGTGATGCAGTTCAACGAGAACCATCAGAGACGTCAGCGGAAAGAAGAGGAGGCCGCTGCCGCGCTCCAGGCTCAGCAGGAACAGCAGAAACAGGAACAACAGAAGCAGGCTCTGGCTGCTCAAGCTGCTCGCGAGAAAGAGGAGGAGGCTGAAGAGCCTGCCGACGACGATGTCATACCGGAACTGACCAGAAGCACTTGCCAGCATTGCAACAAGGAGTTCAGCAGCGTTTGGGTGTTGAAGGCGCACTGCGAGGAGGTGCATCGCGATCTGGTGCCCCGCGAGTTTCTCGAGAAGTACGCGCAACAGTTCAAGTGCGAGTACGAAAAGAAAAGCGTGGTGGTCACCGTCGCAACGTCGTCGTCTACGTCGTCCGCGCCCAGAAGCTCCACTCCCGCGACCGGTCAACCGCAAGATCTCAGCGCTGACAAGGAACAACGTGAGAAGGAAAAGGAGGAGATCGCTGAGAACAAAGAACGCGTCAGCAAAACCCCGGAAGCCACCTCCACCACTCCGGCaacgacgcccgcgttgagcaacacgcccgtgtcgagcaccgattccactacagccaccgtgttacctaccaatcagacgatccactcgcaacaacaacagcagcaacaacagcagcagcagcaacaacaacagcagcagcagcaacagcaacaacaacagcacgctcaacttactctggcgcaacagatgtccgagatgcaggctgctttgaatgcaatggcggcttcgcagttgcaacaacaacttcagcaatatccTGGATTGATGATGGGGATGATGGGTCTCCCGTTAGGGTTGAACGTTCCTGCTTTGGCTGCCATGAACCTCCAACCGCCTCTGGTGCCAATGATGCTACCGCCACCGCCTTATGATGGCGCTGCCACCGCGTATCCGCCGATCAACGCTCAAGCTGATCTTCTGGCTAAACAACATCTCGCTCTGCAACAGCAACAGGCAGCGGCTGCAAGCGCAGCTGCTTCCCAGAAACGTGCTCGCACTCGCATAACAGACGAACAGCTAAAAAATCCTCCGAGCGCATTTCGATATTAA
Protein Sequence
MPSTKAGDEPGGGGGSRGRVPPPAAGAALHQPHHPRTASPPSGTEPCTRDAIPTPTPIADTTTTTTTTTMTMQSQGQQQQEQQGPSPSPSPTGGDVEKFDGKIVYNPDGSAYIIEGESELSEDDSLPDGCIVDGRGVSVPHSLVFPQIASAYYVSRLYAHQAYQQQQQQQQQRSAVQQHNPDLPVMHSYRVISYRSAEGSKQPPPPPTAPPPPAASVPVKPILMCFICKLSFGYAKSFVAHAQGEHQLTLMEDERQVLSHSTASAIIQAVGRGKQPLVSFLEPVTNSTCPQSSPAQMPSQQQQQRAESNEHETPTATSTPASTPGVPSSPQQQQQQQQQRPSPSTPTTPTSHSNHPLSYNHQQPQQHQWTGAQVSAASWAKAPDAMHYTSPPPPTSSTKGSPSSYAALTQQPPNFLTGTTIGVCPEHMQGRPSGVECPKCELILASSRLAGPGGPLAGIHSRNSCKTLKCPKCNWHYKYQETLEIHMKEKHPESETSCIYCIAGQPHPRLARGETYTCGYKPYRCEVCNYSTTTKGNLSIHMQSDKHLNNMQELQQGGGGSSGASNPSSSQDAPMPTRSPHHQQNHSPHIAGQAGNQSKPKPTFRCDVCNYETNVARNLRIHMTSEKHTHNMLVLQQNVKHMQTLSALQSHHQQAQHHHQQAQQQHQQQLEQLLHLGGLDKPQHAEAALADMAYNQALLIQMMTGGQLPPQLPPEIMGGMASMGAMGNLGGDVGLSPDSMDPPPEPADPDPSHLYQCCVCNNFATDSLEALTHHLAVDRTRTREGEILALVAGHFVCKLCSYKTNLKANFQLHCKTDKHLQRLQHVNHVKEGGPRNEWKLKYLASPTSAAQLRCHACDYYTNSAHKLALHAASPRHEAAALLLRHLLEASANVPTQGKLYHCALCGFSARHRLPLLQHVRSLRHLQMEQLHQLHRRSGIQGNETPHTDIGDVFQVVGDPDAPPAQQSSPTTPTTPNATSVNSERREDGSDCGNEVKQEPDNDQETEQEPDNDHEDVSCPYCTYQPTSREELRQHLQVAHVQDSDEKTETVKEEPPPDLLCPLCQDGFRERSALEKHVMQIHSVNADGLQRLLLLVDQSHWLNNNPRNTSTPAVTTPTSPTTTTKPPQEDDINERSGNDEIEEITRCTICGRICRSLEELQQHHRETHPATTPTLAVSEKHVYKYRCGQCSLAFKTLEKLQQHSQYHAIRDATKCALCGRSFRSVQALQRHLESTHADLHEEELAQYKQSLLHAHPLLQALTEESFRRQGNLSGEQSVEDDTSKAEEEESDASDSSPLHKEQRLLEDYLNSQPVAEDSYHDPGRKFKCHRCKLAFTRQSYLTGHNKTLLHRKGEKMSYPMEKYLDPNRPYKCDVCKESFTQKNILLVHYNSVSHLHKLKRAMQEQGNNNTLISVVPPASPTESPDSQQDQDKKPYKCNICKVAYSQGSTLDIHMRSVLHQTRASKLPDLAASGQLDLARPLIEQPPPSSPNSPPVSMNTTSTGMLSCPRCSALFVNQEQLATHQQLYCIFSNPLALFQQLAASQQLVPSTPAKTPPPTSTTPGPQQHMQQSVQHASQATQDILSQPRHKTSQMYKHLLESFGFDLVMQFNENHQRRQRKEEEAAAALQAQQEQQKQEQQKQALAAQAAREKEEEAEEPADDDVIPELTRSTCQHCNKEFSSVWVLKAHCEEVHRDLVPREFLEKYAQQFKCEYEKKSVVVTVATSSSTSSAPRSSTPATGQPQDLSADKEQREKEKEEIAENKERVSKTPEATSTTPATTPALSNTPVSSTDSTTATVLPTNQTIHSQQQQQQQQQQQQQQQQQQQQQQQQHAQLTLAQQMSEMQAALNAMAASQLQQQLQQYPGLMMGMMGLPLGLNVPALAAMNLQPPLVPMMLPPPPYDGAATAYPPINAQADLLAKQHLALQQQQAAAASAAASQKRARTRITDEQLKNPPSAFRY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01268537;
90% Identity
-
80% Identity
-