Loen004963.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Lasioglossum oenotherae
Gene Symbol
mecom-a
Assembly
GCA_028455765.1
Location
CM052290.1:2729764-2747493[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.04 3.3 8.5 0.4 2 23 173 195 172 195 0.93
2 9 0.53 44 4.9 0.1 1 23 202 225 202 225 0.93
3 9 1.3e-05 0.0011 19.4 1.4 1 23 231 258 231 259 0.93
4 9 4.6e-06 0.00038 20.9 2.6 1 23 265 287 265 287 0.95
5 9 2.8e-05 0.0023 18.4 5.0 1 23 293 315 293 315 0.99
6 9 0.00055 0.046 14.3 0.7 2 21 323 342 322 343 0.95
7 9 6.5e-09 5.4e-07 29.8 1.2 1 23 696 718 696 718 0.99
8 9 3.4e-07 2.8e-05 24.4 1.7 1 23 724 747 724 747 0.97
9 9 9.7e-06 0.0008 19.9 3.4 1 23 753 775 753 775 0.99

Sequence Information

Coding Sequence
ATGTGTTTACAACGTGAGAAGAGGGTGTCGGCAGGGGTGGAATTAGTTGGGAGAGGTTCCATCGAAAGGCGCAGGGTGTCCAGGGGCGTATCAGGTAGGGAGCAGACAGCACCCTATTGGATGCTGCAGCGGGAAGTAACAGCGAAAGAGACAGAGAGCAAGGGTGATGAGAGAAGGGCGACGCGCCGATGGGCGTCAGTGCGTACGGCCGGCAGCGGAGTGAGGGGTTGGTTGGACGCATCGCACGAGACGAACAATTGGCTGAAATACATTCGCAGCACCAGCAGTCCTCACGCCGTAAACATGCGCCACGTGCTCATCGGCGGACAGATGGTGTACGAGGCTGTGAGGGACATTGCGGCCGGTGAAGAGCTTCTTCTCGGCGTTCGAGAACCTCTTCAGCTGCAGGACATGCTTGGAGAAAACACAACCGAGGACAGAAGCGATCGAGAGACCGCCTCGCAGCACAGTGGAACCATCGACGAGGATAAAGAGGACGACGAGGAGGGCGAGACCAGGTGCACTGTCTGCGACAAGCCGTTCCAGGACATCGAACTGTTGGACGGGCACCTGGTGACCTGTCACAGATACCCCGCGGAACAGCATCGCTGCGACAGCTGTCCTCGCGCGTACGCCTGGCGACCGTTGCTGGTCCGTCACCGTGCCATCGTCCACGGGGAGCAACGCAACTATCCCTGCGAGAACTGTCCGAAGTCGGACAATCCgcaggtcttcacggatccgtcgaatctccagcgccacatccggacgcaccacgtgggcgcgaggagtcacgcgtgcaccgagtgcggcaaaacgttcgcgaccagttccgggctgaagcagcacactcacatccacagcagcgtgaagccattccagtgcgaggtctgcttcaaggcgtacacgcagttctcgaacctatgccggcacaagcgcatgcacgccgactgtcgcatgcagatcaagtgcgttaaatgcggacagtcgttcagcacggtcacctccttgtcgaagcacaAGCGATTCTGTGACTCGACGCCGCCGCCAGGCCCACCAGGAGCCATGCCGCAATTACCCACCTCGGCTGGCAGCCCTTTCCTCGTCTACCCTCGTCCTCCGGTTGGTCTGCCAGGCGGACTACCCTTCTACCCACCTAGTCTGATGGGCCCCTACCCGGGTCAATTCACTTTCCTCAATACTCCCCTTCTGTTCCCGCCGAAAGTCGAAGAAGCCGAAAAGAGAAGCGACAGTCCGAAGAAGGAGCGCTTCACACCGCCCCGAGTACTTCCTCAACACAGCAAAGTGTCTCCATCGACCGCGGAAGAGGCGACCTCATCGTTCAGGCCCTCTCCCGCCAGACCACCCGTTCAACCCACTCCCGACAGCGACGACGATCCTTCGAAAAAGCGAGAGTCAGCCAGCAGAATAACCGAGAAGAAGATGGACTCCGATCTAGCGTTATCTGCCGCGAATAAGGAGACAACGGACCAGCCCCTGGATCTCAGAGTCCAAACGAAGAAGCAGGAGACGAACTCGAATGCGCCTGAGAGGAAAAGTCACAGTCCCTCGCCAGTTCCAGCGCCGATGGAGGAGGCTCCACCCCCTCCGGATCCTCCGAAGCACGAGGAAGAGACCTCCGCGCCGATGGAAATCGATCCCAAAGACGTTCGCAGCAGTCCTCACATAAGAACAAGTTTATCTGCCGAGCAACCACCAACGAGCACTCCCCCGCATATGGCTTACCCCAGACCTATACACCCCATGTTCCTCGAGGCGATGTATCGCGGACCTGCTGGTGGGTTCCCCGGGTTCCCAGGTGGTCCCCCGCCTCCTGGAGGCGCTGCTCCAGAGTCCAGATTGCTGCCACCGCTGCCACCCTTCGGTCCTCCGCGGGGACTACCTTTTTTAGGAACGCTCATGAACGGGCTCAGCGGAGCTAGGCCTGGCGCGGGAGGATTCGACTTGCTGGGCAGGCCGCCGCTGGGACCGTTCCCCGGCGTGAAGCCGTTCCAGGAGGCTGTGATCGCTCCCCATCATCACCACCATCATCACCACCATccacacggcaagatgaaggaccgatactcctgcaagttctgcggcaaggtgttccccaggtcggcgaacctgaccagacatctgcgtactcatactggcgagcaaccgtacaagtgcaagtactgcgagagatccttcagcatctccagcaacctgcagagacacgtgcggaacatccacgacaaacagaggccattcaaatgtcctctctgcgagaggtgtttcggtcagcagactaatttagacagacacttgaagaaacacgaggctgacgatggTAGCGGTGTTGTATCTGTCGCGGACTCTCCCGGCAGTAGCAACGAGAACGAAAGGGAGGATACGTATTTCGATGAGATTCGCTCGTTCATGGGGAAGGTGACCTACGGAGGGGAAGCTGGTTATGGTTTACCACATCATCCTGCTTATCTGCCGAGCCGCCTGCACGAGATGCACGAATCCAAGATGGAGACAGAGTATGACGAAGACGAGGACAGCGAGGAGGGCGTGTCTCCTCTGGATGAGACTGACGGATTGTCCCCTGTAGAGACCAAAGAGATCACTCCGCCTCCTCAGTACGATCTGAAACTGAGGGAGAAGCAGGAGCTGCTGAACAATAACACGGCCGAGCCGGTGATCGAGATTTCCACATAG
Protein Sequence
MCLQREKRVSAGVELVGRGSIERRRVSRGVSGREQTAPYWMLQREVTAKETESKGDERRATRRWASVRTAGSGVRGWLDASHETNNWLKYIRSTSSPHAVNMRHVLIGGQMVYEAVRDIAAGEELLLGVREPLQLQDMLGENTTEDRSDRETASQHSGTIDEDKEDDEEGETRCTVCDKPFQDIELLDGHLVTCHRYPAEQHRCDSCPRAYAWRPLLVRHRAIVHGEQRNYPCENCPKSDNPQVFTDPSNLQRHIRTHHVGARSHACTECGKTFATSSGLKQHTHIHSSVKPFQCEVCFKAYTQFSNLCRHKRMHADCRMQIKCVKCGQSFSTVTSLSKHKRFCDSTPPPGPPGAMPQLPTSAGSPFLVYPRPPVGLPGGLPFYPPSLMGPYPGQFTFLNTPLLFPPKVEEAEKRSDSPKKERFTPPRVLPQHSKVSPSTAEEATSSFRPSPARPPVQPTPDSDDDPSKKRESASRITEKKMDSDLALSAANKETTDQPLDLRVQTKKQETNSNAPERKSHSPSPVPAPMEEAPPPPDPPKHEEETSAPMEIDPKDVRSSPHIRTSLSAEQPPTSTPPHMAYPRPIHPMFLEAMYRGPAGGFPGFPGGPPPPGGAAPESRLLPPLPPFGPPRGLPFLGTLMNGLSGARPGAGGFDLLGRPPLGPFPGVKPFQEAVIAPHHHHHHHHHPHGKMKDRYSCKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHDKQRPFKCPLCERCFGQQTNLDRHLKKHEADDGSGVVSVADSPGSSNENEREDTYFDEIRSFMGKVTYGGEAGYGLPHHPAYLPSRLHEMHESKMETEYDEDEDSEEGVSPLDETDGLSPVETKEITPPPQYDLKLREKQELLNNNTAEPVIEIST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01539779;
90% Identity
iTF_00763389;
80% Identity
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