Basic Information

Insect: Lasioglossum marginatum
Gene Symbol: mecom-b
Assembly: GCA_028455795.1
Location: CM052242.1:3813390-3847747[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.046 4.4 8.2 0.4 2 23 366 388 365 388 0.93

2 9 0.62 58 4.6 0.1 1 23 395 418 395 418 0.93

3 9 1.3e-05 0.0013 19.3 1.2 1 23 424 451 424 452 0.93

4 9 5.3e-06 0.0005 20.6 2.6 1 23 458 480 458 480 0.95

5 9 3.2e-05 0.0031 18.1 5.0 1 23 486 508 486 508 0.99

6 9 0.00064 0.06 14.0 0.7 2 21 516 535 515 536 0.95

7 9 7.5e-09 7.2e-07 29.5 1.2 1 23 893 915 893 915 0.99

8 9 4e-07 3.8e-05 24.1 1.7 1 23 921 944 921 944 0.97

9 9 1.1e-05 0.0011 19.6 3.4 1 23 950 972 950 972 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.046	4.4	8.2	0.4	2	23	366	388	365	388	0.93
2	9	0.62	58	4.6	0.1	1	23	395	418	395	418	0.93
3	9	1.3e-05	0.0013	19.3	1.2	1	23	424	451	424	452	0.93
4	9	5.3e-06	0.0005	20.6	2.6	1	23	458	480	458	480	0.95
5	9	3.2e-05	0.0031	18.1	5.0	1	23	486	508	486	508	0.99
6	9	0.00064	0.06	14.0	0.7	2	21	516	535	515	536	0.95
7	9	7.5e-09	7.2e-07	29.5	1.2	1	23	893	915	893	915	0.99
8	9	4e-07	3.8e-05	24.1	1.7	1	23	921	944	921	944	0.97
9	9	1.1e-05	0.0011	19.6	3.4	1	23	950	972	950	972	0.99

Sequence Information

Coding Sequence: ATGGTTGAACAAGTACTTGTGGCCTCTGTCAAGGGAATGAAAACGTCGAAGCACTCGTGTCCCACAGGAGTCAAAGACCCCTGGGCGTCAAGAGTTTTCCAAATATTGTTGATGTATCGTATCGACGAGTCGCACGAGAGGATCCTCAAGTTTCCTATCCGGATGGGGAGAGGAAGCAGCGACGAAGGCGAGTCGACGTCTGGCACGCCGGGCGGCAGTGGTGCCGGTGAGAACGCTGAGATGGAGGAGAACGGGTCGATTCGAGGAggtagcaacagcaacagcaacagcaacagcaacagcaacagtggtaccagcaatcctgtgtacAGGGACTTGAAGGCCCTTCACGCGACCAGTGCCCACGATGTCCCGCAGGACTACAATCCTCAATCCAGGCCCGCTTATCAACGAGGCTACTCGCCAGCCATGGACAAGCAACCAAGCTACGAAAAGGATCGGCACAGAGCATCGTCCAGGGAAGACGAAAAGTCCTGGGACTACGAAAAAACCGACCGCAAGGACTACTCCAGTTCCCGGGACGCTTACAGAACCGATTCCTATCCTTTGCCGTTCGCAGAGGACGCGGTGAAGCAGGAGCAGAAGGAGCAGTCGAGCCGCGAGTGGATGTCACCTGTGCCGGAAGTCGAGGTGGGAGGTTCATCGCCCGGAGGTCCTCAGGTTCGAGCGAGGAAAGACATTCCACGGGGTGCAAGGTTCGGCCCGTTTCTCGGGAAATGGGCTAGCGAGCCTTTCAACCCCCGCTACGCCTGGGAGGTGCGTACGTCCGGCAGCGGAGTGAGGGGTTGGTTGGACGCATCGCACGAGACGAACAATTGGCTGAAATACATTCGCAGCACCAGCAGTCCTCACGCCGTGAACATGCGCCACGTGCTCATCGGCGGACAGATGGTGTACGAGGCTGTGAGGGACATTGCGGCCAGTGAAGAGCTTCTTCTCGGCGTTCGAGAACCTCTTCAGCTGCAGGACATGCTTGGAGAAAACACAACCGAGGACAGAAGCGATCGAGAGACCGCCTCGCAGCACAGTGGAACCATCGACGAGGATAAAGAGGACGACGAGGAGGGCGAGACCAGGTGCACTGTCTGCGACAAGCCGTTCCAGGACATCGAACTGTTGGACGGCCACCTGGTGACCTGTCACAGATACCCCGCGGGACAGCACCGCTGCGACAGCTGTCCTCGCGCGTACGCCTGGCGACCGTTGCTGGTCCGTCACCGTGCCATCGTCCACGGTGATCTACGCAACTATCCTTGCGAGAACTGTCCGAAGTCGGACAATCCGCaggtcttcacggatccgtcgaatctccagcgccacatccggacgcatcacgtgggcgcgaggagtcacgcgtgcaccgagtgcggcaaaacgttcgcaaccagttccggactgaagcagcacacccacatccacagcagtgtgaagccgttccagtgcgaagtctgcttcaaggcgtacacgcagttctcgaacctatgccgacacaagcgcatgcacgccgactgtcgcatgcagatcaagtgcgttaaatgcggacaatcgttcagcacggtcacctccttgtcgaagcacaAGCGGTTCTGTGACTCGACGCCGCCGTCAGGCCCACCGGGAGCCATGCCGCAATTACCCACGTCGGCTGGCAGCCCTTTCCTTGTCTACCCTCGTCCCCCGGTTAACCTACCAGGCAGACTACCCTTCTACCCACCTAGTCTGATGAGCCCCTACCCGGGTATCTTCCCGAATGCCCCCAATTTCATCAATACTCCCCTTCTGTTCCCGCCGAAAGTTGAAGAAGCCGAAAAGAGAAGCGACAGTCCGAAGAAAGAGCGCTTCACACCGCCCCGAGTACTTCCTCAACACAGCAAAGTGTCTCCATCGACCGCAGAAGAGGCGACCTCATCGTTCAGGCCCTCTCCCGCCAGACCACCTGTTCAACCCACTCCTGATAGCGACGACGATCCTTCGAAGAAGCGAGAGTCAGGCAACAGAACAACCGAGAAGAAGATGGACTCTGATCTAGCTTCATCTGCCGCGAATGAGGAGACAACGGACCAGCCCCTGGATCTCAGAGTCCAAACGAAGAAGCAGAATACGAACTCGAGCGCGGCTGAGAGGAAGAGTCACAGTCCTTCGCCGGTTCCACCGTCGATGGAGGAGGCCCCGCCCCCTCCGGATCCTCCGAAGCACGAGGAAGAGACCTCCGCGCCGATGGAAATCGATCCCAAAGACGTTCGTAGCAGTCCTCACATAAGAACCAGTTTATCTGCCGAGCAACCACCAACGAGCACTCCCCCGCATATGGCTTACCCCAGACCTATACACCCCATGTTCCTCGAGGCGATGTATCGCGGACCTGCTGGTGGATTCCCCGGGTTCCCAGGTGGTCCCCTGCCTCCTGGAGGCGCTGCTCCGGAGTCCAGATTGCTGCCACCGCTGCCACCCTTCGGTCCTCCGCGGGGACTCCCTTTTTTAGGAACGCTCATGAATGGGCTCAGCGGAGCTAGGCCTGGTGCGGGAGGATTCGACTTGCTGGGCAGGCCACCGCTGGGACCGTTTCCCGGCGTGAAGCCTTTCCAGGAGGCCGTGATCGCTCCCCATCATCACCACCATCATCATCACCATCCACATGGCAAGATGAAGGACCGATATTcctgcaagttctgcggcaaggtgttccccaggtcggcgaaccttaccagacatctacgtactcatactggcgagcaaccgtacaagtgcaagtactgcgagagatccttcagcatctccagcaacctgcagagacacgtgcggaacatccacgacaaacagaggccgtttaaatgtcccctctgcgagaggtgtttcggtcagcagactaatttagacagacacttgaagaaacacgaggctgatgatggTAGCGGTGTTGTGTCTGTTGCGGACTCTCCCGGAAGTAGCAACGAGAACGAAAGGGAGGATACCTATTTCGATGAGATTCGCTCGTTTATGGGGAAGGTGACTTACGGAGGGGAAGCTGGTTATGGTTTACCACATCATCCTGCTTATCTGCCGAGTCGCCTGCATGAGATGCACGAGTCCAAGATGGAGACCGAGTACGATGAAGACGAGGATAGCGAGGAGGGTGTGTCTCCTCTGGATGAGACTGATGGATTGTCCCCTGTAGAGACCAAAGAGACCACTCCGCCTCCTCAGTACAATCTGAAACTGAGGGAGAAGCAGGAGCTGCTGAACAATAACACAGCCGAACCGGTGATCGAGATTTCCACATAG
Protein Sequence: MVEQVLVASVKGMKTSKHSCPTGVKDPWASRVFQILLMYRIDESHERILKFPIRMGRGSSDEGESTSGTPGGSGAGENAEMEENGSIRGGSNSNSNSNSNSNSGTSNPVYRDLKALHATSAHDVPQDYNPQSRPAYQRGYSPAMDKQPSYEKDRHRASSREDEKSWDYEKTDRKDYSSSRDAYRTDSYPLPFAEDAVKQEQKEQSSREWMSPVPEVEVGGSSPGGPQVRARKDIPRGARFGPFLGKWASEPFNPRYAWEVRTSGSGVRGWLDASHETNNWLKYIRSTSSPHAVNMRHVLIGGQMVYEAVRDIAASEELLLGVREPLQLQDMLGENTTEDRSDRETASQHSGTIDEDKEDDEEGETRCTVCDKPFQDIELLDGHLVTCHRYPAGQHRCDSCPRAYAWRPLLVRHRAIVHGDLRNYPCENCPKSDNPQVFTDPSNLQRHIRTHHVGARSHACTECGKTFATSSGLKQHTHIHSSVKPFQCEVCFKAYTQFSNLCRHKRMHADCRMQIKCVKCGQSFSTVTSLSKHKRFCDSTPPSGPPGAMPQLPTSAGSPFLVYPRPPVNLPGRLPFYPPSLMSPYPGIFPNAPNFINTPLLFPPKVEEAEKRSDSPKKERFTPPRVLPQHSKVSPSTAEEATSSFRPSPARPPVQPTPDSDDDPSKKRESGNRTTEKKMDSDLASSAANEETTDQPLDLRVQTKKQNTNSSAAERKSHSPSPVPPSMEEAPPPPDPPKHEEETSAPMEIDPKDVRSSPHIRTSLSAEQPPTSTPPHMAYPRPIHPMFLEAMYRGPAGGFPGFPGGPLPPGGAAPESRLLPPLPPFGPPRGLPFLGTLMNGLSGARPGAGGFDLLGRPPLGPFPGVKPFQEAVIAPHHHHHHHHHPHGKMKDRYSCKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHDKQRPFKCPLCERCFGQQTNLDRHLKKHEADDGSGVVSVADSPGSSNENEREDTYFDEIRSFMGKVTYGGEAGYGLPHHPAYLPSRLHEMHESKMETEYDEDEDSEEGVSPLDETDGLSPVETKETTPPPQYNLKLREKQELLNNNTAEPVIEIST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01539779;
90% Identity: iTF_00118172;
80% Identity: -