Basic Information

Insect: Lasioglossum malachurum
Gene Symbol: zfh1
Assembly: GCA_028455605.1
Location: CM052317.1:203120-208795[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.2 15 6.3 0.8 2 23 107 128 107 128 0.95

2 7 2.7e-05 0.002 18.5 0.6 2 23 147 168 146 168 0.97

3 7 4.1e-06 0.0003 21.1 5.6 1 23 177 199 177 199 0.99

4 7 1.6e-05 0.0012 19.2 1.9 1 21 205 225 205 226 0.95

5 7 0.00035 0.026 15.0 4.6 1 23 676 698 676 698 0.93

6 7 0.00039 0.029 14.9 8.4 1 23 704 726 704 726 0.98

7 7 0.0017 0.13 12.9 4.3 1 21 732 752 732 753 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.2	15	6.3	0.8	2	23	107	128	107	128	0.95
2	7	2.7e-05	0.002	18.5	0.6	2	23	147	168	146	168	0.97
3	7	4.1e-06	0.0003	21.1	5.6	1	23	177	199	177	199	0.99
4	7	1.6e-05	0.0012	19.2	1.9	1	21	205	225	205	226	0.95
5	7	0.00035	0.026	15.0	4.6	1	23	676	698	676	698	0.93
6	7	0.00039	0.029	14.9	8.4	1	23	704	726	704	726	0.98
7	7	0.0017	0.13	12.9	4.3	1	21	732	752	732	753	0.96

Sequence Information

Coding Sequence: ATGCTGCATCCCCATAAAATCATCGGGACGCTCGGTGTGGATGCAGCCGCGAACACAGACCGCGGTCTGTTATTACTACGCTATGTATCTACAGCGAGAGGTTGCAGCGAGGACGAGGCAGCAGGTGTCGTGAACGCGGAGGTGGGCGGAGGTTGCGCGGCCGGGGCGCCAACCACAGGAGGTGCTGTTGGAGGTGGTAGCGGGCCAGGTAGCGAGGCTGTCAGTGGTGGTGGTGGTGGTGGTGGTGCTGGTGGTGGTGGCAGTGGCAACGCGGGGGCGGGTGGTAGCGAGGGTGGATCGACGAAACAGGGTGGCGAGAGGTGTCCACAGTGCGGCATCCTCTGCCGGGACGTCCACGTCCTTCAGGTCCATCTCGAGGAGCACAAGACCACCTACGCCATCGACAAGAACGATCTCAACGCTCAGTTCCCCCAAGTGTCCTGCAAGGTGTGCAGCAAGACCTTTGCAAACGTCTACCGACTCCAGAGGCACATGATCAGCCATGATGAGAGTGCCGTGCTTCGTAAGTTTAAGTGTCCCAATTGCGAGAAAGCCTTCAAGTTTAAGCATCACCTCAAGGAGCACCTTCGCATCCACAGCGGTGAAAAGCCATTCCAATGCAACAATTGCGGCAAACGTTTCTCTCACTCTGGCTCGTACTCGAGTCACATGACATCGAAGAAGTGCTTGATCGTGAACCTGAAGAAGTCGAGGCACGCGAACGTGACGAGCGTCGATCGCGGCCCGAAAAAACCGCAACAGCCTCTGCCGCCTTTGAGACGCGAGGTCGATTTACTTGCCGCGAACAATAACACTTTCCTCCCCATTCTACCAAAGCTTTCGCCCTCGGACTACCAGGAAATACAACGAGAAGGAGCAGGTATTTACGACATACCGACACTCCTGCCCCGAATGATGGCGTTCGGCAGCTACTTCCTGCAGACGTCTCTGGGCAAAATGCTAAATCAGCTGCATTCGAAGAGATTGGACGAGGTAGCCGAGCAATTCGAGTCTCATCGGGAGCTGATGAGCCCATCGACAGCGGATTCTGAAGGGACCGAGGGCACGGAAGGAACGGAAGGCAAAGAATCCCCTGCGCCGACTGATTCTCAGGGTTTGGATGCGGTTCGACGGATCTTGGAAACGGTCAACACCTCGGTGACGAAACAGCTGTTGGAAGCGAACGTGCGAAAACTGTCGACTTCACCGGCTACCATGAAGAGAGAGTTCGATGACGATTATCAAGATCAAGATAGCGAAATGTCCAGCGAGATGGCTCACTATCCAGATTGGTCGACGACGGATCAATATGATTCCCAGAGCGAAGGTTTAGCTGCGAAGCTCGAGGACGTAAATCAGCCGAGCGCGAAATCGAGCTGCAAGAGGAAAGCCGAAGACAGCTCGGAAGCGGACTCTGAGGACGAGGAGGATGCCACGCAGACACACAACGACAACGGGAGGAGGGTGAGGGCCAGATCGTTGATAGACGACGAGCAATTGGCCGTCCTGAAAGGATACTACGCCATTAATCCTCGGCCTAAGAAGGAGGAGATCATCATGATCGCGAATTACATCAATTTCCCCACTCGAGTCGTACAGGTATGGTTCCAAAATTCCCGAGCGAGGGATCGACGGGAATCGAAGATCCCAGCCCTGGTACCGCTGACAAATCCAGCTAGTCAGACTGCCATCGAGCAACCCTTGGACCTATCGAAAAAGGAGGCTCTCACGGAGTCAGCGTGCAAGGAGAACGACACCAGTTGGGTCAAGGTAGCGACTTCCTCACCTGACGAGCCAAAGAACGACAACCCTCCGTCGCATAATCCAGACGCGGACGACATGGAGGACTCGCCTCTAGTTATAGACGAAGAGACCACCACCGACTCCGTGGAAACGAAACGCACGGCTCCAACTCCTGTTGGAGAAACTGTTCCGAAGACTCAACCTCAGGCGAACGTGAAGAACGAGAACGAAAACGCGAGTCAATCTGAGGCAACGCCAGCTGCTGAAGTCGAGCAGGGTGTCTTCTTCTGTGATCGGTGTGACAAAACATTTTCCAAACACAGTTCCCTAGCGAGACATAAATACGAACATTCCGGGCAAAGGCCGTACAAATGTGTAGAGTGCACAAGGGCATTCAAGCACAAGCACCATCTGACCGAACACAAGCGACTGCACAGCGGCGAAAAGCCTTTCCAGTGCTCCAAGTGCCTAAAGCGCTTCTCTCACTCCGGCTCCTACAGCCAGCACATGAATCACCGTTTCTCTTACTGCAAACCGTATAGAGAATAG
Protein Sequence: MLHPHKIIGTLGVDAAANTDRGLLLLRYVSTARGCSEDEAAGVVNAEVGGGCAAGAPTTGGAVGGGSGPGSEAVSGGGGGGGAGGGGSGNAGAGGSEGGSTKQGGERCPQCGILCRDVHVLQVHLEEHKTTYAIDKNDLNAQFPQVSCKVCSKTFANVYRLQRHMISHDESAVLRKFKCPNCEKAFKFKHHLKEHLRIHSGEKPFQCNNCGKRFSHSGSYSSHMTSKKCLIVNLKKSRHANVTSVDRGPKKPQQPLPPLRREVDLLAANNNTFLPILPKLSPSDYQEIQREGAGIYDIPTLLPRMMAFGSYFLQTSLGKMLNQLHSKRLDEVAEQFESHRELMSPSTADSEGTEGTEGTEGKESPAPTDSQGLDAVRRILETVNTSVTKQLLEANVRKLSTSPATMKREFDDDYQDQDSEMSSEMAHYPDWSTTDQYDSQSEGLAAKLEDVNQPSAKSSCKRKAEDSSEADSEDEEDATQTHNDNGRRVRARSLIDDEQLAVLKGYYAINPRPKKEEIIMIANYINFPTRVVQVWFQNSRARDRRESKIPALVPLTNPASQTAIEQPLDLSKKEALTESACKENDTSWVKVATSSPDEPKNDNPPSHNPDADDMEDSPLVIDEETTTDSVETKRTAPTPVGETVPKTQPQANVKNENENASQSEATPAAEVEQGVFFCDRCDKTFSKHSSLARHKYEHSGQRPYKCVECTRAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRFSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00086058;
90% Identity: iTF_00864529;
80% Identity: iTF_00863168;