Lfig014919.1
Basic Information
- Insect
- Lasioglossum figueresi
- Gene Symbol
- Zfa
- Assembly
- GCA_028455805.1
- Location
- CM052195.1:892338-897733[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 18 0.69 64 4.5 0.6 2 23 69 89 68 89 0.91 2 18 0.00043 0.04 14.6 4.6 1 23 94 117 94 117 0.98 3 18 0.043 4 8.3 4.8 1 23 123 146 123 146 0.95 4 18 0.00014 0.013 16.1 1.4 1 23 152 174 152 174 0.98 5 18 6.8 6.4e+02 1.3 1.0 2 22 180 200 179 202 0.79 6 18 0.00037 0.035 14.8 1.5 1 23 209 231 209 231 0.97 7 18 1.1e-06 0.00011 22.7 0.2 1 23 235 257 235 257 0.98 8 18 5.3e-05 0.005 17.4 2.3 1 23 263 285 263 285 0.98 9 18 4.1e-06 0.00038 20.9 1.0 1 23 291 314 291 314 0.97 10 18 9.1e-05 0.0085 16.7 0.9 1 23 461 484 461 484 0.96 11 18 1.7e-05 0.0016 19.0 4.0 1 23 490 512 490 512 0.98 12 18 0.011 1 10.2 7.6 1 23 521 544 521 544 0.94 13 18 0.00082 0.076 13.7 1.2 1 23 550 572 550 572 0.95 14 18 1.9e-05 0.0018 18.8 2.4 1 23 577 600 577 600 0.96 15 18 0.0085 0.8 10.5 2.8 1 23 606 628 606 628 0.97 16 18 5.6e-07 5.2e-05 23.6 0.5 1 23 632 654 632 654 0.98 17 18 0.00064 0.059 14.0 7.4 1 23 660 682 660 682 0.99 18 18 4.6e-05 0.0043 17.6 3.2 1 23 688 710 688 710 0.97
Sequence Information
- Coding Sequence
- ATGTCCCCGGCACGACGCTGGAAATCAATGTTGCAGAGACTGAAGAGAAGAGAGGTGAGACGAAGAGTTCTAGTCAAAACGCCGTCGTCGCTAACGGCTTCGTTCTCGAGAAGATCGAAGAACGCTGCGAAGAAGTCGATGAAAGAGAAGCTGAAGCAAAAGGAGAGAAAGAGATACGAAGAAACGCTGGAGCTCGAGAAAATTTACTGCGACGTCTGCAAAGCTACGGTTTTCGAACGGAATTACAAGAAACATTTGCTACGGCACAACTTCAAGGACTACCAATGCGACACGTGCTTGAAGAAGTACAAACATAAACGAGCATTGACCAAACACAAACTGACTATTCACGGAGACGCGCCTCTGCACAATTGCCAATACTGCGACTTCATGACGGTCCACTTCTCCTACTTACGGgtacacgtgatgcgcaagcacaacaatacgtttccgttttcctgtcagaaatgcgaccgcagatttcgcataagagccgactacatgaagcacatagtgacccacgacggcgagccgtgcatctgcgacgtgtgcggcgcgaaagtgccgaataaaatatcgctgtacttccacaagaactacaatcacacggtgaaggacgccaagttcccgtgtaccatgtgcaacaagaagctgcagagccagaagaacctggacagccacatgcaacagcacagccggaagttcatctgcgaggagtgcggactcggattgacccgcaagtccggcctcagaaagcacataaggacgcattccggcgagaaatcgttttcgtgtcacatttgccagaagacgttcgccagtgcgacgagcagaaaagtacaccttttgacgcattccggtgttagaccctacgtttgcacgatttgcggacagagtttcacccaacgaccggccctttgcgtgcactggaagaagcagcatccagatgccacggaaacgttaccttctgtgtccataactaacattatccacagcgtcacgaagaaCATTAAGTTGGATGACGCGAAATCAGCGCAACATTTAACACGGAGGAATAAGCACACCCCCGATGAACAGGTTAACGAGCCGAAAGCTCCACGTAAAATCCCGGCTAATCATCACAGGAGAATAGCATTTCGAGTTTCAAAGAACCAAAAACGTAACAAGTGTCCTAACAAAAAGGAACCAGAGAATGGTCCAAACCCGCGAGAAGAGAACGCAGTTCTCCAAAAGAGGGTACGAAGAGTGTCCACGAGCCGGAAGTCAGTGTTGAACACGAGGAAGAACGGATCGACGAAGAACAGCAGCTTGGACAGCTTGCGGAGCAATGAAAGCACCGGCCAGCAAGAAGACCTATACAAGAAGCTTCACGACGGCTCCTacacctgcgacatttgccagacggtgttcgagcagaagagcaagatccttcggcacatcaccagcaagcacagtttccatcggccgttcaagtgcgcgacctgcgacaagacgttcaagtacaaatgcgacttgaaggcgcatagactcgtgcaccaggacgtggactcgagcctcctccattgctgcgacaaatgtgactatcgtacgaagacgaagaacaacctgaagtcccactacatccgacggcacaccgacgactacaagttcgcctgcgagcactgcggcaagcgcttcaagatggaatgggacttgaagttccacatcggcacgcacggcacgtctcagcacatgtgcgacgtgtgcgggaagttttacacgagcaattactccctgtacaagcaccggaaggtggcacatttgaacgagtacaagttccactgcaccgtttgcaacaaacgactcctcacgcaggagaacctggacaatcacatgaagcagcataacagaacgtacgagtgcaaggagtgcggcaaggtgttcgcctcgaaaaggtacctggccactcacgtgaccacacacaccggggtcaagccgtacacctgtcacatttgcaaaaagaacttccgcacgtcgcacatgaggaacacgcatctgctgacccactcggccgagaggccgcatatttgcgatctctgtggacagtctttcaaaaggcggtactacatgatcgagcaccggagaaagcatcccgatgcgcatttgtcTTCGCCTCCTATACCTCTTGGGAAAAACAAAGGCGTTGTTGACACGGGACTAGACGGCGTGACTGAATCTCAGACAGATATTTCATAG
- Protein Sequence
- MSPARRWKSMLQRLKRREVRRRVLVKTPSSLTASFSRRSKNAAKKSMKEKLKQKERKRYEETLELEKIYCDVCKATVFERNYKKHLLRHNFKDYQCDTCLKKYKHKRALTKHKLTIHGDAPLHNCQYCDFMTVHFSYLRVHVMRKHNNTFPFSCQKCDRRFRIRADYMKHIVTHDGEPCICDVCGAKVPNKISLYFHKNYNHTVKDAKFPCTMCNKKLQSQKNLDSHMQQHSRKFICEECGLGLTRKSGLRKHIRTHSGEKSFSCHICQKTFASATSRKVHLLTHSGVRPYVCTICGQSFTQRPALCVHWKKQHPDATETLPSVSITNIIHSVTKNIKLDDAKSAQHLTRRNKHTPDEQVNEPKAPRKIPANHHRRIAFRVSKNQKRNKCPNKKEPENGPNPREENAVLQKRVRRVSTSRKSVLNTRKNGSTKNSSLDSLRSNESTGQQEDLYKKLHDGSYTCDICQTVFEQKSKILRHITSKHSFHRPFKCATCDKTFKYKCDLKAHRLVHQDVDSSLLHCCDKCDYRTKTKNNLKSHYIRRHTDDYKFACEHCGKRFKMEWDLKFHIGTHGTSQHMCDVCGKFYTSNYSLYKHRKVAHLNEYKFHCTVCNKRLLTQENLDNHMKQHNRTYECKECGKVFASKRYLATHVTTHTGVKPYTCHICKKNFRTSHMRNTHLLTHSAERPHICDLCGQSFKRRYYMIEHRRKHPDAHLSSPPIPLGKNKGVVDTGLDGVTESQTDIS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -