Lcon024643.1
Basic Information
- Insect
- Lapara coniferarum
- Gene Symbol
- ZFX
- Assembly
- GCA_949316025.1
- Location
- OX438930.1:28923030-28929162[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 24 0.033 2.8 9.5 0.2 2 21 113 132 112 133 0.94 2 24 0.2 17 7.0 0.9 1 23 163 185 163 185 0.96 3 24 0.00034 0.029 15.7 0.2 1 23 189 211 189 211 0.96 4 24 0.0016 0.14 13.6 2.6 1 23 244 267 244 267 0.94 5 24 0.00023 0.019 16.3 1.0 1 23 273 295 273 295 0.98 6 24 0.004 0.33 12.4 4.2 1 23 302 324 302 324 0.98 7 24 0.00046 0.038 15.3 0.1 1 21 339 359 339 360 0.95 8 24 0.0079 0.67 11.4 2.4 2 22 469 489 468 489 0.88 9 24 0.16 13 7.3 0.3 3 23 495 515 494 515 0.94 10 24 0.64 54 5.4 3.9 2 23 521 543 520 543 0.94 11 24 0.099 8.4 8.0 5.9 1 23 548 570 548 570 0.97 12 24 0.4 34 6.1 4.9 1 21 573 593 573 594 0.95 13 24 0.00031 0.026 15.9 0.4 1 23 606 629 606 629 0.95 14 24 5.2e-06 0.00044 21.4 2.1 1 23 635 657 635 657 0.99 15 24 0.00098 0.083 14.3 0.6 1 23 722 745 722 745 0.95 16 24 0.0047 0.39 12.1 1.1 2 20 856 874 855 876 0.91 17 24 0.003 0.25 12.7 0.8 3 23 911 932 910 932 0.98 18 24 0.00033 0.028 15.8 1.1 2 23 938 959 937 959 0.97 19 24 0.65 55 5.4 1.6 2 21 963 982 963 983 0.93 20 24 1.2e-06 9.9e-05 23.5 0.4 1 23 1009 1032 1009 1032 0.96 21 24 0.00052 0.044 15.1 0.5 1 23 1038 1060 1038 1060 0.95 22 24 0.091 7.7 8.1 0.1 1 23 1066 1088 1066 1088 0.97 23 24 0.0012 0.099 14.0 0.8 1 23 1094 1117 1094 1117 0.95 24 24 0.00055 0.047 15.0 3.6 2 23 1124 1146 1124 1146 0.96
Sequence Information
- Coding Sequence
- ATGGTGGGGACCAGCTCCGTGCTGCCAAATAAATTGTGCAATCTCTGCATGGCGCACATAACCGCCTTCATACCATTCCTGCTCCTGTGCAAGGAGTCCGCCCAGCGGTGGGACCAAATCACAGGAATGTTGAAGGATATCAAAGTCCCAAAGAAAGCAAAAAGTTATTACGTCTTAGTTCTAAAGGATATACGGGCTTATTCTAGTACGAGAACCGCTGAAAGCGAAAAAGATGCTTTACAGAATTTGAAGACTAAGATAACAAATAGAAAATCTTACACCAAGAGGTTAGCAAAAGAGGGTCGCATGACTAGAATGAGGGATGCGACGAAAATGACGTGCCCCGAATGCAAAAGTGTCTTTACAAACATTGTAAAGTTTAATACacatataaaaaacataaacaagAGAATGTGCGCACTCTGTAACGTTCTAATAGACTTGAAGACGTACGAAGCACATTTGAACACTCACGCTGACAGGGTTTTTACTTGTAATATGTGCCCCGAGGCATTTCTAAAAGAAAAGTCCCtatatcttcataaattaaaacacaaagGAGACCATGTTTGCGTGGAATGCAAGTTGAGTTTCGTGACGTCTGCGAACCTCTCCGCTCATTTAGTAATACACCAGTCGCAAGTCTGCGCTGGGTGCGGTAATAAGTTCAATAGGATATGCTACACGAAACATAAACAAAAGTGCTCATTTATagaagaaaatagaagatttatCTGTGACTACTGTTCCAAAGAATACAACCGAAGAACTACGCTAAAAATGCATATAATTCACAACCATTTGGCTGGAAAGCAATTTCAGTGTGACCAGTGTGGTAAGACGTTCCTCAGTCGCGCGCATTTGGCAGAGCACGGCAACACTCACAACAAAATTCTCGATCGATACATCTGCTCGAAGTGCGGCACCAAGTTCAGCACAAGGAGAGGCCATGAGAGGCATTTGAGGAAACACGAGTCTGGCACTTACGGAGTTAGGTCCAAAAAGAAGACCAAATATGTTTGTCCGATTTGTAAGAAGGTTTACTCCCAAAAGAAAAGTATTGACAGTCATCTGAGGGTGCGAGAGGAGCCCGCGTTGCCGCAGGGCCTGTGCAGGAGCTGTTCCGAGCAGGCCATGGCTGCCGTGCGGTACCGGCAGCTATGCATCCAGTCCAACCAACAATGGAGAGACGCCACTGTCTGCCTTGCACAGATACACGCCGCCGCAGATGACGACAAAACCTTCTTCATACTCTACAACGGGCACATGATGATCATCAAGGACCAGGTCGCGCGCGTGCCGAACGAAACCGAGGCTGTAAAGAGGATCAATCTCAGATTCACTGATCCAGAGCCTCACCGGCCGCCCAAAAGGGTAAAGCGCTCATTCCCGCCTGTTAGTTGCCAATGCCCGGACTGTGATAAGAGATTTTCAAATACGGAATTCTTGAACTTCCACCTAAAGACCTCATTGAAACGAGCATGTCAAATATGCGGCGTAGTCATTCAAAAAAAGAACCTGTCGAAACACTTGCAAGAAAAACATGACATATCAGTGGTGGAGTGTAGTGTGTGCCACAGCATCTTCGACACGCATCAGCAACTCGAACAGCACAGCGCCACTTGCCATGGCCCTGACACGTATTCCTGTCACTGCTGCGGCAGCGGATTCAGCAACCACAGAGCCCTGCGCGCCCACATGTACTCGCACACGCTGTTCCATTGCGATGCTTGTGGAACGAGCTTCGAGAATCGTAAATGCTACAAGTATCATCAGAAACAGTGCAAGAGATCAGACGGGCCGCAGCAAGATCTGTACATATGTGACTACTGCAATATAGAGTACAATAGGAAACCGTCGTTACGAATCCATATGATTCAGAAGCACTTGAATATCAACCCGTACGTGTGCCAAGTGTGCGGCAAAAGGGCTTCGACGATGTCGCACTTGAAATCGCACATGAAGACGCACAACGCGACGCGCAGCGTATACCAGTGCCACTGTGGCGCGAAGATGCGTACGGAGGTCGGATACCAGCTACACCAACGGATCCACTCGGGGGAGAGACCGTACGAGTGCGAGGCGTGTGGCGACCGGTTCCTATCGGCGTCGCGACGGCTCGACCATATAAAGCGGAGGCACCGCGGCTCCGCGGACATGCCGCACGCCTGCTACAAGTGCTCCGCCACTTTCATTAGACCTTGGGAGCTGCGGAAGCACTACGCGACTGTTCACAACGATATAAAGGAAGAATCATTATGTCCGAACACGGCATGCGTGGCGTGTGCCAGCACGGCCCTGGCCGCGCAGGAATTCAGATACTTCGTCCAATCGTCGCATAACATGTGGAATAAAGCCATCACTAACCTCTCGGGGCTGCCAACCACAATGTCTTCCCCTCTGAAGTCTCTCTGTGTGCTCATAACGCCGAACGACATGCGCGTACAGACAGTGAAAAACTACGCCAATGGTGATGCTAAAACTGTATTAAACAGGCTCAAAGCAGGGATCGGTAGAAAGCCATTTGGGCGGAAACCTCGCACCGACCGCACGGGCCCTTCGTGCACGTGTCCAGACTGTGGCAAGAGCTTCCTCAGTCCACACTTCTTGAACATGCACCTTATAAACAGTGGACAGAAGGAAGCGTGCGTGCTATGCGGCAACGTGGTGTTACGCGGCCAGCAGATGAAGGAACACATGAGCGCCGCGCATCGCACCGACCTACTACTCTGCAATGAATGCCCGCTATTGTTCTCCACTGAACAAGAGCTAGCCAAACACATAAAAATGTGTCACCAACCAGGTTGTTCAACGTGCGGTGAATGCGGCAGGAGTTTTCCGAGAAAAGTGGCCTTCGATCATCACACACAGATGCATATGGTGAGGACGTGTCGCAGCTGTGGCGCGCAGTTCACGAACCGAGGGTGTTACAGAGAGCACAGGATGCAGTGTGAGCCTGACGCGAAACCGAACATCGATAGTGTGCCTCGTGCTCGCCGCTCCAACATCCGCGACCCGGCGACCTACACATGCGACTACTGCGGCAAGACGTACTCGTCGAGGCCGCAGCTCAAGAACCACATCCTATGGATCCATATGGACGTGCGCCCGCATCAGTGCCAGTGGTGCGGGAAACGGTTCTACACGCCGGCTCGACTTGCCGAGCACACAGTGGTACACACGCGAGTGAGAAACTTTGAGTGCGACATCTGTGGTGCTAAATTGGTGACAAAAATGGCAGCGATATATCACAAGCGACGGCATACCGGTGAGCGGCCGTATAAGTGCGAGGACTGCGGGGAGAGCTTCATATCATCCTCGCGCAGATCCGAGCATGCTAAGCGGAAACACAATAGAGGCATAAAGCCGCAGTGCCATTTATGTCCAGCCAATTTTGTCAGGAAGCATGAGTTGAAGAAACACATAGAAAAGAACCACCCGTGA
- Protein Sequence
- MVGTSSVLPNKLCNLCMAHITAFIPFLLLCKESAQRWDQITGMLKDIKVPKKAKSYYVLVLKDIRAYSSTRTAESEKDALQNLKTKITNRKSYTKRLAKEGRMTRMRDATKMTCPECKSVFTNIVKFNTHIKNINKRMCALCNVLIDLKTYEAHLNTHADRVFTCNMCPEAFLKEKSLYLHKLKHKGDHVCVECKLSFVTSANLSAHLVIHQSQVCAGCGNKFNRICYTKHKQKCSFIEENRRFICDYCSKEYNRRTTLKMHIIHNHLAGKQFQCDQCGKTFLSRAHLAEHGNTHNKILDRYICSKCGTKFSTRRGHERHLRKHESGTYGVRSKKKTKYVCPICKKVYSQKKSIDSHLRVREEPALPQGLCRSCSEQAMAAVRYRQLCIQSNQQWRDATVCLAQIHAAADDDKTFFILYNGHMMIIKDQVARVPNETEAVKRINLRFTDPEPHRPPKRVKRSFPPVSCQCPDCDKRFSNTEFLNFHLKTSLKRACQICGVVIQKKNLSKHLQEKHDISVVECSVCHSIFDTHQQLEQHSATCHGPDTYSCHCCGSGFSNHRALRAHMYSHTLFHCDACGTSFENRKCYKYHQKQCKRSDGPQQDLYICDYCNIEYNRKPSLRIHMIQKHLNINPYVCQVCGKRASTMSHLKSHMKTHNATRSVYQCHCGAKMRTEVGYQLHQRIHSGERPYECEACGDRFLSASRRLDHIKRRHRGSADMPHACYKCSATFIRPWELRKHYATVHNDIKEESLCPNTACVACASTALAAQEFRYFVQSSHNMWNKAITNLSGLPTTMSSPLKSLCVLITPNDMRVQTVKNYANGDAKTVLNRLKAGIGRKPFGRKPRTDRTGPSCTCPDCGKSFLSPHFLNMHLINSGQKEACVLCGNVVLRGQQMKEHMSAAHRTDLLLCNECPLLFSTEQELAKHIKMCHQPGCSTCGECGRSFPRKVAFDHHTQMHMVRTCRSCGAQFTNRGCYREHRMQCEPDAKPNIDSVPRARRSNIRDPATYTCDYCGKTYSSRPQLKNHILWIHMDVRPHQCQWCGKRFYTPARLAEHTVVHTRVRNFECDICGAKLVTKMAAIYHKRRHTGERPYKCEDCGESFISSSRRSEHAKRKHNRGIKPQCHLCPANFVRKHELKKHIEKNHP
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -