Lpop016562.1
Basic Information
- Insect
- Laothoe populi
- Gene Symbol
- ZEB2
- Assembly
- GCA_905220505.1
- Location
- HG992159.1:18051220-18070811[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 0.64 61 5.3 0.1 2 23 7 28 6 28 0.97 2 14 0.005 0.47 12.0 0.8 1 23 984 1007 984 1007 0.93 3 14 8 7.6e+02 1.9 0.2 1 23 1078 1100 1078 1100 0.90 4 14 3e-05 0.0029 18.9 1.6 2 23 1103 1124 1102 1124 0.97 5 14 4.6e-05 0.0043 18.4 1.1 1 23 1130 1152 1130 1152 0.99 6 14 0.03 2.8 9.5 2.5 2 23 1159 1180 1158 1181 0.95 7 14 0.061 5.8 8.5 1.2 5 23 1194 1212 1193 1212 0.96 8 14 0.00026 0.025 16.0 1.7 3 23 1219 1240 1218 1240 0.97 9 14 0.038 3.6 9.2 0.2 2 23 1271 1291 1270 1291 0.96 10 14 0.0081 0.76 11.3 0.7 5 20 1301 1316 1297 1319 0.85 11 14 0.0069 0.66 11.5 2.5 1 23 1327 1349 1327 1349 0.98 12 14 0.0092 0.87 11.1 7.0 1 23 1355 1377 1355 1377 0.98 13 14 7.1e-06 0.00067 20.9 1.3 1 23 1383 1407 1383 1407 0.98 14 14 0.0011 0.11 14.0 5.1 1 23 1413 1435 1413 1436 0.95
Sequence Information
- Coding Sequence
- ATGGATCACTCGCAAGTGCAGTGCCCCGTATGTACTCTGTACCTTCGCAATGGGATGACCCTGGAGTCTCACCTGGACACTCATCCCAAAGACCAGGTGATCAAAGCTCTTTGCTGTCTTACTACCAAGGGCAACAACTTTGGAAGCAGAACCTCCACCCCACTGCATTCAGAGCGCTCTTTCAGGAGTCGATCCCGCACCCCTGCTGCTGATGATAGATGGAATGGTTCACAAAGCGCTGAACATGATAGATACTGGAGGAGACCACCAAGCAGGACACCTAAATCTACACCTGTGACTAGTGTGTCTGGAAGTGGAACTCCAGAAATAAGGATGACGGAAATGCAATTTGAAGGTGTTTCAAATGGACAGCATTCATTGCCACCTTATCTTATGAAAAGTGATAAGACACAGCAAACATATCAGAATACAACAATGTCAGACTATGATCCGTCATATAGTTTCTATCAAGACCAGCAAGAAGATAGAGAGATCAAGTTCTCCCGCAGTGCAGAATACTCTGCAATGGATAGTAGTAATGTGTTCACATATAACATGCCCACAGTGGCCACAGGAGTGAGGTTCCAAGCAAATAACAATCTGTTACCAAGTACATCAAAGAAACAACctgattttgttaaaattttaccAAAACCAAGCAATATTGTAGTCAAAACTAATGTTGGTGGTGTCCAGTACATAGCATCTGGAGTGAAGCCCATGCATGTGATGATGCCATCGACACCTACCTTCGTACCGAAAAATATCCACAACAATATGATACTGCCAAGCAGTACCCACTCGTCTATGAATATTGACAAGGCAGTACCTTCACAAATGAACTCCAACCCTTTTAATATAATGCCTGGAAATTTACCACCAGGAATGTCGACAGTCATGACGCAGAACTCACAGATAATATACAGAGAAATGGTGCATAATATAGATGGTAAACCTTTTATTTCTAGTGTGCCTGCCGTCATGACAACAGGGAGTGCATCTACCTTAGCTCAGACCAGTCCTTTATACCAAAATGTGATGGTCGTGGATCAATTTGGTTCATGTATGTACAGCACCCCACAGCATCTCCTTCCTAAGTCTTGCACTACTTCTATTTATCCTGAGAGTGGATCTATTGTACCTGGCAGTCAAATGAATAAATCACCTGTTCCTAGTGATCCTAAGACTTTGGTAATTGAAGTAGGTCCTATATTACCATCACAGAGTGCTTCTCCTTGCACTACAGCACCAAGCACTGCCATATCTACCCCAGCAACAATTATAAAGACTGATAAAGATAGTATCAGTGTGAAATCAGACTCTAGAAGTGATGCATCTGGGTCAACTAAGGGTCTGAAAATTTTAAGCAATATTAAAGTAGAAGTGCCTGTtcaacataacaaaaatatggTGAACACAATCATGGATCTAACGGAGTCTAATGACCAGGAGTACTTAGAAGAGGAAAAAAACTGTCCAAAACCAGagaaaataatgttaaaaatgaATGACAAACTAAGTTCAGAAAACAGCACACCTCGACCTTCCAGTTCTAGTAATGACAGTGTAGTTTCTCATTCGTTCTCTGTGATAAAAAATGTCGGCAACCCTCCATCGTACAAAGGCTCGTCCAGCAAAGCATTAGATAGCAAATTGGACACTGAGTATGGTGACAGCTGTCCTGTGCCTGATCTTATATGTAACGAGAAACCCTCAATCTCACCTTGCAGTGAATTATCTGAGAATGGGGAGAATTCAATAGACCGCACATCACCATCTCCGAAACTGGATCATGAtaggaaaataaaaaagaaagagaTAGAGGATAACATTCAAGTAACTGTAAAGCCATATAGGTTAAATGCACTAAGACTGAACAATCTTTATGTTAAAAAGAACAAGAaagttttacaaataaaaaatgctaAGCAACTTGGGACAAGTAGTTCCAGTAATATGGATACAGAGCCAATGCCATCCTCCAGCAGGTTACCAGAAGATTATTCAATAAAGAATCACATTGAGAGAGTTGAAAACATAGATCATTCAACCTTACAAACTGTATCTGTTGAAGAAATAAAGGATAATGACGATAATGATGACAACAATGGGTTTGACGCAGACACAGAAGAGCATTCTTTAGATATGGAACCCCCATTGCAGCCCATAATCAATAGCACAACAGAGTTCTCGACAACTGTAGACATGGTACAAGTGAAAGAAGAAATAAGCACTAGCAACGAAAGCGCATTTAGCAGTGCGACTCCAGACCGTGTTCTCGCGCCAATGGAGACACTTAGACCTGTTAATGTGATAACCTACGGCAATCTCCCTGCAGACAATTTTGACGAAGAATCAAACCACAGAGAACTAATGAGCATTGAAGCCGCGTCCAAAAACAAACAGTTCGTAAGCATGATGAACGAAAATTACTTTGGCGATAATTTGTATGCGGATTACTTTTCGCAAGATCGGGCAGAACCGTTCGAAAATCGACAACCTCCAGTGAAAGAACCCATGTATGGTATGTGGGGGGAATCCTCGCAGAAAGACAATGAGTTCATACTGCCAAATTTTATTCACGAGAGCTACAAAATAACTGAAGGTGGGTATTCAGAGATTGGAAGCAGGGAAGTTATTGCTGATGGTGATGGGGATGTGTGCGAGAGGGACAGTAAAGCAGACGTTCTGAGTGAGGGTAGGAGTGAGGGAGAGGCTCCATTGAACATCTGTGCGGACGAGCGTATGCCGCCGCGCGGGGAGCTTAGCGGCCAGGAGAGCAATGGGGATATGGAGTCAGCTTGGAATGgaATGTACCCTGAGGTGGCTCCTCCGGAGTCGTACGACCTGATGGCGCGCGAGAGCTGGATCTCGGACGGATCTGACATCGATGTTGGAGAGAAGAGAGAGACGTTAGACGAGGATATACAGTACCCCAAAGCCCGCACGCACACATGTGTACAATGCAATTTGAAGTTTCCGACGCCCAAGGAGTTGCGCATGCATCGTGCGCAGGCGCATGCTACACCCGGGAAGACTTCATACAGCCGTATGATCACAGCACGGGCTATAAAGAAAGAAGAGAAGACGGATGACAATATGATGGGATGCGCAATAATAGACTCGAAGGAATCAATCACATCATCAATACTCCAAGTGTACGAAATGGATGAGACGAAGACGAAGATCGAAGGCATCATCAAGCAGGAGGCCAAGCGGAGACGGAAAGACTTTGTCTGCCCCACCTGCAAGGTGGACCAGCAGTCGGCCGCGGCGTTTCATGCACACCTCAAAATCCACCCCCTCGAGTGCCTTACTTGCGGGAAATGCTTTTACAGAAGAGCTTACCTCGCACTGCATATAAAAACGCATTTaggtattaaaaattacaaGTGTGACGTGTGCGAGAAGCGGTTCATAACCCGTCAGAAGTTGTCCGAGCATCAGAACGTGCACACCGGCCGCGCGCCCGTCAAGTGCACCGTCTGCGAGGACACCTTCCGCAGATACTCCAACATGGTGCAGCATAGGGACCGTCACCACTTCGGCAAGCGGGCCCGCGTGCGCGACTTCGTGTGCCAGTGCGGCGCCGTGTTCCACTCGCGGGCCAAGCTGCGCTGGCACCAGGAGACGCACGAGCCGCGACCGAAGGCCTGCATGTACTGCAGCGAGAAGTTCGTGCACGCGTCGTCGCTCACACGTCACGTGCGACGCACGCACAACCAGTACTACGTGCCACCACCCCTtaccaccgccaccaccactgcCGCCACCACCACCAAGACACGACGGCCGGCGCCGGAGAATGTGCCGTGTCCTGTCTGCAAACAGATATACCTCCGAACGAACCTGCGCTCTCATCTCCAAACGCACAGCGGAAAGCGGCCGTTCCTCTGCATCGTGTGCAACAAGGCGTTCACCACCAAATGGAACCTCAAACTGCATCGCTGGACCCACATGAGCCGCTCATCTAAGCCGTTCAAATGCCACCTCTGTAAAGGTGCCTTCTACAAACAGACAGAGTTCATCTCGCATATGAACGCGCACAAGTCTGTCAGACCGTACACTTGTAACTACTGCGGCTGCCAGTTCATAAGGAGGTATAACTGTCAGAGGCATGTCAGAGAACACGAAATGGATAAGAAGTACGTGTGTAAAGTGCCAGAGTGCGGGAAGTCGTTCCACAGGAGCTATTACTTGTCTGAACATATGAAGGTACATAGCGGTGCGCGGCCCTTCTCCTGCAATATTTGCGGTAAGACGTCTAGTAACAAATCTAATCATAATAAACATGTTAAGATACATCATGCCCGCGAGCCGGTCGCCACTGAGGCGTAA
- Protein Sequence
- MDHSQVQCPVCTLYLRNGMTLESHLDTHPKDQVIKALCCLTTKGNNFGSRTSTPLHSERSFRSRSRTPAADDRWNGSQSAEHDRYWRRPPSRTPKSTPVTSVSGSGTPEIRMTEMQFEGVSNGQHSLPPYLMKSDKTQQTYQNTTMSDYDPSYSFYQDQQEDREIKFSRSAEYSAMDSSNVFTYNMPTVATGVRFQANNNLLPSTSKKQPDFVKILPKPSNIVVKTNVGGVQYIASGVKPMHVMMPSTPTFVPKNIHNNMILPSSTHSSMNIDKAVPSQMNSNPFNIMPGNLPPGMSTVMTQNSQIIYREMVHNIDGKPFISSVPAVMTTGSASTLAQTSPLYQNVMVVDQFGSCMYSTPQHLLPKSCTTSIYPESGSIVPGSQMNKSPVPSDPKTLVIEVGPILPSQSASPCTTAPSTAISTPATIIKTDKDSISVKSDSRSDASGSTKGLKILSNIKVEVPVQHNKNMVNTIMDLTESNDQEYLEEEKNCPKPEKIMLKMNDKLSSENSTPRPSSSSNDSVVSHSFSVIKNVGNPPSYKGSSSKALDSKLDTEYGDSCPVPDLICNEKPSISPCSELSENGENSIDRTSPSPKLDHDRKIKKKEIEDNIQVTVKPYRLNALRLNNLYVKKNKKVLQIKNAKQLGTSSSSNMDTEPMPSSSRLPEDYSIKNHIERVENIDHSTLQTVSVEEIKDNDDNDDNNGFDADTEEHSLDMEPPLQPIINSTTEFSTTVDMVQVKEEISTSNESAFSSATPDRVLAPMETLRPVNVITYGNLPADNFDEESNHRELMSIEAASKNKQFVSMMNENYFGDNLYADYFSQDRAEPFENRQPPVKEPMYGMWGESSQKDNEFILPNFIHESYKITEGGYSEIGSREVIADGDGDVCERDSKADVLSEGRSEGEAPLNICADERMPPRGELSGQESNGDMESAWNGMYPEVAPPESYDLMARESWISDGSDIDVGEKRETLDEDIQYPKARTHTCVQCNLKFPTPKELRMHRAQAHATPGKTSYSRMITARAIKKEEKTDDNMMGCAIIDSKESITSSILQVYEMDETKTKIEGIIKQEAKRRRKDFVCPTCKVDQQSAAAFHAHLKIHPLECLTCGKCFYRRAYLALHIKTHLGIKNYKCDVCEKRFITRQKLSEHQNVHTGRAPVKCTVCEDTFRRYSNMVQHRDRHHFGKRARVRDFVCQCGAVFHSRAKLRWHQETHEPRPKACMYCSEKFVHASSLTRHVRRTHNQYYVPPPLTTATTTAATTTKTRRPAPENVPCPVCKQIYLRTNLRSHLQTHSGKRPFLCIVCNKAFTTKWNLKLHRWTHMSRSSKPFKCHLCKGAFYKQTEFISHMNAHKSVRPYTCNYCGCQFIRRYNCQRHVREHEMDKKYVCKVPECGKSFHRSYYLSEHMKVHSGARPFSCNICGKTSSNKSNHNKHVKIHHAREPVATEA*
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00859741;
- 90% Identity
- -
- 80% Identity
- -