Basic Information

Gene Symbol
-
Assembly
GCA_013368075.1
Location
JABVZV010000424.1:249587-250728[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 5.1e-05 0.00073 20.0 2.0 1 23 67 89 67 89 0.98
2 9 1 14 6.5 1.8 12 23 92 103 90 103 0.92
3 9 3.3 47 4.8 1.7 1 23 108 130 108 130 0.78
4 9 0.00024 0.0034 17.9 4.6 1 23 135 157 135 157 0.99
5 9 0.057 0.8 10.4 1.9 1 23 162 184 162 184 0.97
6 9 0.012 0.17 12.5 1.4 1 23 189 212 189 212 0.98
7 9 8.5 1.2e+02 3.5 2.9 1 23 217 239 217 239 0.87
8 9 0.39 5.5 7.8 5.1 1 23 244 266 244 266 0.98
9 9 0.4 5.7 7.7 6.5 5 23 301 319 298 319 0.95

Sequence Information

Coding Sequence
atgaagGAGAATGAAGAATTGAAAAGGGAATTGGTAAATTTTGAAACACCTTTTAAATGGGAAGAGGATAACCTTCTGGAGCACAAAGATATACATGCTTTACCCACGcatcaatatatttataatgaatgtaattttattatgccaaaagttttttttttatcaccaCAGTTGGACACTTCAAAAAGTAATGATAAATTTgaatgtaacgaatgtgattataaaacaccgcGGAAGCACAACCTAAAGgagcatgtaaaaattcatagtgtgaggaattatcatttaaaaatgcatatgagaattcatactggCAATCcgtataagtgtaaggaatgtgatcataaaacaccatggaaacagacAATAAAGGAGCATGCGAAACTTCATGCTGATgtagaatataagtgtaataaatgtaactataaaacaacTAAGAAACGCACTCTACAAATGCATATGAAGATTCAtactggcgatgaatataaatgtaacgaatgTAATTACAAATCTCTGCGGAAGCAGAATATAAAAGAACATctgaaaattcataccggtgctgaatataaatgtaaggaatgtggttATAGAACACAGTGGAAACGAAGTCTAAAAGAGCATGTGAGAAGAATTCATAGTAGTGATAAATAtacatgtaaaaaatgtgattataatatgtCATGGATACgttatctaaaggaacatgtgaaaattcatactagagatgaatataagtgtaaagaatgtgattataaaacgcagtGTAAACAAAGTCTAAaacaacatgtaaaaattcatactggagATGAATATAAGTATAAGgactgtgattataaaacattgtggaaacaaaatctacagcatcatgtgaaaattcatacaggtgatgaacataagtgtgaatgtgactataaaacagtgagcaATCAccatttaaaaatgcatatgaaaattcatactggcgcACACTAG
Protein Sequence
MKENEELKRELVNFETPFKWEEDNLLEHKDIHALPTHQYIYNECNFIMPKVFFLSPQLDTSKSNDKFECNECDYKTPRKHNLKEHVKIHSVRNYHLKMHMRIHTGNPYKCKECDHKTPWKQTIKEHAKLHADVEYKCNKCNYKTTKKRTLQMHMKIHTGDEYKCNECNYKSLRKQNIKEHLKIHTGAEYKCKECGYRTQWKRSLKEHVRRIHSSDKYTCKKCDYNMSWIRYLKEHVKIHTRDEYKCKECDYKTQCKQSLKQHVKIHTGDEYKYKDCDYKTLWKQNLQHHVKIHTGDEHKCECDYKTVSNHHLKMHMKIHTGAH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-