Basic Information

Gene Symbol
-
Assembly
GCA_013368075.1
Location
JABVZV010002194.1:55963-57193[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.0072 0.1 13.2 0.4 1 21 67 87 67 88 0.96
2 12 0.37 5.3 7.8 1.8 1 23 94 116 94 116 0.97
3 12 0.17 2.3 8.9 5.6 1 23 121 143 121 143 0.98
4 12 0.0031 0.044 14.4 2.0 1 23 148 170 148 170 0.99
5 12 0.014 0.2 12.3 0.9 1 23 175 197 175 197 0.98
6 12 0.007 0.099 13.3 1.1 1 23 202 224 202 224 0.98
7 12 0.014 0.2 12.3 1.1 1 23 229 251 229 251 0.98
8 12 0.011 0.15 12.7 0.5 1 23 256 278 256 278 0.97
9 12 0.0035 0.05 14.2 5.0 1 23 283 305 283 305 0.97
10 12 0.00016 0.0023 18.4 1.0 1 23 310 332 310 332 0.98
11 12 0.018 0.25 12.0 0.9 1 23 337 359 337 359 0.99
12 12 0.033 0.47 11.1 1.0 1 23 364 386 364 386 0.98

Sequence Information

Coding Sequence
ATGGACGTtgatgttattgaaaattctgcaataaaatctgaagtgattttaacagaaacgttttcgttttgtgaaaaatatgaagaTTGTTCCAGTGAAAAGCTGAAACCAGAACCAATAGATTACGAAGaatcatttaaatgtaacaaagaTGATGTTGCAGAGGACACGAATATACAGTCTACTGCCATTCAACAATAtacttgtaatgaatgtaattttgagaCAACGGAGAAAAGTTTCCTAATTCAACatttaagaattattaaaaatgttcaatatttttgtaatgaatgtaattataccacattaatcaaaaattatctaaggaaacatgtgaaaattcataaaaatactGAATATACTTGcgagaaatgtgattataaaacaaggtGGAAACATTGTCTAAAgatacacatcaaaattcatacaggtaacgaatataagtgtaatgaatgtaattataaaaccgTGTGGAAAACGAATTTAAGGCAACATGTCAAGACTCATataggtgataaatataagtgtagcaaatgtgattttaaaacggtgtggaaaagtagtctaaatgtacatgtcaaaatccatacagaggatgaatataagtgtaatgaatgtaattataaaacagtgtggaaaactaatttaaaggaacatgtcaagattcatataggtgatgaatacaagtgtaacaaatgtgattttaaaaccgtgtggaaaagtagtctaaacgaacatgtcaaaattcatacagatgacgaatataagtgtatagaatgtgattataaaacagtgcagcCAAATTACCTCAaacaacatgttaaaattcatacaggtaatgaatataaatgcaatgtatgtaattataaaacatttcatcaaaaatctctaaagcaacatgtcaaaattcatacaggtaacgaatataagtgtaacgaatgtgattataaaacaatccAGCCAAAATATCTAAAGCAACATGCCAAAATTCATGCTGGTAACGAATATAAATGtagagaatgtgattacaaaacagtgtggaaaaacagtctaaaggaacatataaaaattcatacaggtgatgaatataagtgtaaggaatgtgattttaaaacagtgtggaaaggtaatctaaacgaacatttcaaaattcatacaggtgacgaatattag
Protein Sequence
MDVDVIENSAIKSEVILTETFSFCEKYEDCSSEKLKPEPIDYEESFKCNKDDVAEDTNIQSTAIQQYTCNECNFETTEKSFLIQHLRIIKNVQYFCNECNYTTLIKNYLRKHVKIHKNTEYTCEKCDYKTRWKHCLKIHIKIHTGNEYKCNECNYKTVWKTNLRQHVKTHIGDKYKCSKCDFKTVWKSSLNVHVKIHTEDEYKCNECNYKTVWKTNLKEHVKIHIGDEYKCNKCDFKTVWKSSLNEHVKIHTDDEYKCIECDYKTVQPNYLKQHVKIHTGNEYKCNVCNYKTFHQKSLKQHVKIHTGNEYKCNECDYKTIQPKYLKQHAKIHAGNEYKCRECDYKTVWKNSLKEHIKIHTGDEYKCKECDFKTVWKGNLNEHFKIHTGDEY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-