Basic Information

Gene Symbol
-
Assembly
GCA_013368075.1
Location
JABVZV010001223.1:1995858-1998222[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.022 0.32 11.7 0.1 1 21 68 88 68 89 0.95
2 16 0.01 0.15 12.7 1.3 1 23 152 174 152 174 0.98
3 16 0.05 0.7 10.6 0.5 1 23 179 201 179 201 0.98
4 16 2 28 5.5 0.9 1 23 206 228 206 228 0.95
5 16 0.0015 0.022 15.3 2.5 1 23 233 255 233 255 0.99
6 16 0.32 4.6 8.0 0.5 1 23 260 282 260 282 0.96
7 16 0.091 1.3 9.8 3.9 1 23 287 309 287 309 0.98
8 16 0.00047 0.0066 17.0 1.2 1 23 314 336 314 336 0.99
9 16 3.2 46 4.9 0.9 1 23 368 390 368 390 0.95
10 16 0.0037 0.053 14.1 1.0 1 23 395 417 395 417 0.99
11 16 9.3e-05 0.0013 19.2 2.0 1 23 422 444 422 444 0.98
12 16 0.13 1.9 9.3 0.5 1 23 449 471 449 471 0.97
13 16 0.00019 0.0028 18.2 5.0 1 23 476 498 476 498 0.98
14 16 0.1 1.5 9.6 0.7 1 23 505 527 505 527 0.97
15 16 0.5 7.1 7.4 1.4 1 23 532 554 532 554 0.98
16 16 0.033 0.47 11.1 2.6 1 23 559 581 559 581 0.99

Sequence Information

Coding Sequence
ATGGACGTCgattataatgaaagttatccaataaaatcagaagtaattGTACAGGAAACATTTTCTTACTgtggaaaatatgaagATTATGGGAATGAAACATTGAAAATGGAGAAAGTAGGTTTTGAAGATTCTTTTAAATCTgaatttgacaataattttgTGAAGCACATCAATATATGCGGTGTACCCACAtatcaatatatttgtaatgaatgtaattttattacaacagaGAAAGATTCTCTAacagaacatttgaaaattactaagaacattcaatatttttgtaaggtaTGTGACTTTAACAGCAGGATGAGATGTGCGATAAGAGAGCATTCCAGTATTCACAACAAGATTGGTAGTAGACAAAttggtaaaaaatataactttaagACATTACGACTTTTCGCTTTACCATCTGAAttgaaaattccaaaaaatgatGGTGAATATAACTGTacagaatgtgactataaaacacagAGGAAAGGGaggctaaaggaacatgtgaaaattcatattgatgatcaatataagtgtaaggaatgtgattacaaaacaccgtGGAAAGAAAGTCTAAAAGGTCATGTGAAAATTCATTCCGGTGATGAATATAcgtgtaataaatgtatttataaaacgcCATGGAAAGggagtttaaaaaaacatgtgaaaattcacactgacgataaatataaatgtaaggaatgtgattataaaacaagttGGAGACGGAGTCTAAAGATTCATATGAAAACTCATACTgatgatgaatacaagtgtaaagaatgtgattttaaaacagtatggaaacggAGTTTAGTGGAACATGccaaaattcatagtggtgatgaatacaagtgtaaggaatgtcaCTATAAAACACTGAGGAAAGATAGACTAAAggcacatgtgaaaattcattccggtgatgaatataagtgtaaagaatgcgactataaaacagtgaggaaagatAGACTAaatgaacatgtaaaaattcatactggtgatgaatataagtgtaacaaaTGCATTTATAAAACGCCTTGGAAACGGAGGCTAAGTGAACATGTGAAACTTCATACTGATcccaaatataagtgtaacgaatgtatttataaaacaccatggaaacagagtttaaaaaaacatgcgaaaattcatactgacgataaatataagtgtaaggaatgtgattataaaacaccgtgGAAAGAAAGCCTAAAAagacatgtgaaaattcatactgatgataAATATGATtgtaagaaatgtgattatCAAACAAGTTATAAAGCAAGTCTAAAGGTTCATATGAAAACTCATACGGATGATGGatacaagtgtaaggaatgtgattttaaaacagtatggaaacagAGTTTGGAGGTACATGCCAAAATTCATTGTAGTGATGAATATAACTGTAAGGAATGCGACTATAAAACATGCAGAAAACGGAATCTAAATGATCACATAAAAACTCATAAAAGCACTGGCcatcaatataagtgtaaggagtgtgattataaaacaggatggaaacagagtttaaaggaacatgtgcaAATTCATGCCgctgatgaatataaatgtaatgagtgtatttataaaacaccattTAAACAGAAGTTAAGAGAACATGTGAAGATTCATACTAAttctgaatataagtgtaagaagtgtgattataaaacatggCGGGAATGGTATTTAAAGCAACATGTAAAAACTCATACTGAAGATCACTag
Protein Sequence
MDVDYNESYPIKSEVIVQETFSYCGKYEDYGNETLKMEKVGFEDSFKSEFDNNFVKHINICGVPTYQYICNECNFITTEKDSLTEHLKITKNIQYFCKVCDFNSRMRCAIREHSSIHNKIGSRQIGKKYNFKTLRLFALPSELKIPKNDGEYNCTECDYKTQRKGRLKEHVKIHIDDQYKCKECDYKTPWKESLKGHVKIHSGDEYTCNKCIYKTPWKGSLKKHVKIHTDDKYKCKECDYKTSWRRSLKIHMKTHTDDEYKCKECDFKTVWKRSLVEHAKIHSGDEYKCKECHYKTLRKDRLKAHVKIHSGDEYKCKECDYKTVRKDRLNEHVKIHTGDEYKCNKCIYKTPWKRRLSEHVKLHTDPKYKCNECIYKTPWKQSLKKHAKIHTDDKYKCKECDYKTPWKESLKRHVKIHTDDKYDCKKCDYQTSYKASLKVHMKTHTDDGYKCKECDFKTVWKQSLEVHAKIHCSDEYNCKECDYKTCRKRNLNDHIKTHKSTGHQYKCKECDYKTGWKQSLKEHVQIHAADEYKCNECIYKTPFKQKLREHVKIHTNSEYKCKKCDYKTWREWYLKQHVKTHTEDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-