Basic Information

Gene Symbol
-
Assembly
GCA_013368075.1
Location
JABVZV010001931.1:2452009-2453146[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.25 3.6 8.4 0.3 1 21 64 84 64 85 0.93
2 9 0.019 0.26 11.9 0.6 1 23 148 170 148 170 0.98
3 9 7.7e-05 0.0011 19.4 3.9 1 23 175 197 175 197 0.99
4 9 0.0027 0.039 14.5 1.1 1 23 202 224 202 224 0.99
5 9 6.3e-05 0.00089 19.7 2.4 1 23 229 251 229 251 0.99
6 9 2.4e-05 0.00034 21.0 1.1 1 23 256 278 256 278 0.99
7 9 0.019 0.26 11.9 2.6 1 23 283 305 283 305 0.98
8 9 6.6e-05 0.00093 19.6 1.5 1 23 310 332 310 332 0.99
9 9 3.5e-05 0.00049 20.5 5.2 1 23 337 359 337 359 0.99

Sequence Information

Coding Sequence
atGGATGTTGATCctattgaaagttgtgcaataaaatctgaagtgattttaacagaaacgttttcattttgtggACAATACCTAGATTGTGGGGATAGAGATTTAAAAACAGAGCCAGTGGATTATGAAGAATGTAAGGAAGATGTTTCTGTAGAACAGATGAGCATGCATGTTGTTCCGatgcaacaatttttttgtaatgagtGCGACTTTATGACATTGCAAAAAGATTCTCTAAAAGAACACTTGaatattactaaaaatgttcaatatttttgtaaggagcGTAACTTTACAACTCAATTACAATGTTCAGTAAAAAAGCAATTCGGGACTCACAAAGGGGTAGatgataaatatattattggagAATTTAATTCTCAAACATCGCAGAATTTCTGTTTAACACCGCAgtggaaaacaacaaaaagtagtgacaaatatatatgtaatgaatgtaattatactacATTAATCAAAGGCTACTTAAGAagacatattaaaattcataaaggggctaagtataagtgtaaagaatgtgactataaaacagtgcgaaaatatcatctaaaggaacatgtcaaaattcatacaggtgatgaatataagtgtaaagaatgtgattataaaactatatggcaaagtagtctaaagacacatgtcaaaattcataccggcgataaatataagtgtaaagaatgtgattataaaacagtacgaaaaTATTACCTAAAccaacatgtgaaaattcatacaggtgatgaatataagtgtaaagaatgtgactataaaacagtgcaaaaagattatctaaaggcacatgtcaaaattcacaccggtgataaatataagtgtaaagaatgtgattataaaacagtgtggcataGTAGTCTAAAgacacatgtcaaaattcataccggcgataaatataaatgtaaagaatgtgattatgaaacagTACGAAAATATTACCTAAaccaacatgtcaaaattcatacaggtgatgaatataaatgtaaagaatgcgactataaaacagtgcgaaaagatcatctaaagaaacatgtcaagaGACACAGGTGA
Protein Sequence
MDVDPIESCAIKSEVILTETFSFCGQYLDCGDRDLKTEPVDYEECKEDVSVEQMSMHVVPMQQFFCNECDFMTLQKDSLKEHLNITKNVQYFCKERNFTTQLQCSVKKQFGTHKGVDDKYIIGEFNSQTSQNFCLTPQWKTTKSSDKYICNECNYTTLIKGYLRRHIKIHKGAKYKCKECDYKTVRKYHLKEHVKIHTGDEYKCKECDYKTIWQSSLKTHVKIHTGDKYKCKECDYKTVRKYYLNQHVKIHTGDEYKCKECDYKTVQKDYLKAHVKIHTGDKYKCKECDYKTVWHSSLKTHVKIHTGDKYKCKECDYETVRKYYLNQHVKIHTGDEYKCKECDYKTVRKDHLKKHVKRHR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-