Basic Information

Gene Symbol
-
Assembly
GCA_013368075.1
Location
JABVZV010001401.1:637700-648593[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.061 0.86 10.3 1.4 1 23 97 119 97 119 0.98
2 12 0.0065 0.091 13.4 0.5 1 23 124 146 124 146 0.99
3 12 0.0005 0.0071 16.9 4.8 1 23 151 173 151 173 0.99
4 12 0.018 0.26 12.0 0.3 1 23 178 200 178 200 0.98
5 12 0.002 0.028 15.0 0.7 1 23 205 227 205 227 0.99
6 12 2.1e-05 0.0003 21.2 2.6 1 23 232 254 232 254 0.99
7 12 0.13 1.8 9.3 0.5 1 23 259 281 259 281 0.97
8 12 1.9e-05 0.00027 21.3 2.9 1 23 286 308 286 308 0.99
9 12 3e-05 0.00043 20.7 2.0 1 23 313 335 313 335 0.99
10 12 0.0063 0.089 13.4 1.6 1 23 340 362 340 362 0.99
11 12 0.76 11 6.9 1.9 1 23 367 389 367 389 0.95
12 12 6.7e-06 9.5e-05 22.8 2.9 1 23 394 416 394 416 0.99

Sequence Information

Coding Sequence
ATGGATGTCGATAATAATGAAAGTAATCCAGTAAAAACGGAAGTGATTGTaaaggaaacatttttattttgtgaaaaatatgaagtttataacaaaaatgttcagtatttttgtaaggaatgtaacatTAACACTTGGTTCGCATGTTCGATAAAAGAACATTTCAGGATACATAACAGTGTTGCTTGTAGACATACTACTAAATCATGTACCTTTAAGAGACCACAGTTGAAAACGCCTTTGAAAGGAAGATTAAAGGCACATGTAAAAAATCGTAccggtgaagaatataagtgtaaggaatgcgattataaaacgcagtggaaacggagtctaaaggaacatgcgagaattcatactggtgatcaatataaatgtaaggaatgtgattataaaacagtttggaaacagagtctagaggcacatctgaaaattcatactggtgatgaatataagtgtaaagaatgtgattataaaacgacgACGAAAcgttgtctaaaggaacatgtgagaattcatactggtgatcaatataaatgtaacgaatgtgattataaagctGTTTGGAAACAGAGCCTACAGGCACatctaaaaattcatactggtgaagaatataagtgtaaggaatgtgattataaaacagttcgGAAACTGAGACTAATTGAACATATacaaatccatactggtgatgaatataagtgtaaagaatgtaactataaaacagtgcgaaaaaatgatctaaagaaacatataaaaattcatactggtgaagaatataagtgtaaggaatgtgattataaaacaatttggaaACAGAGACTAATTGAACATATacaaattcacactggtgatgaatataagtgtaaggaatgtaactataaaacagtgagaaaagatagtctaaagaaacatctgaaaattcatattggtgaaaaatataagtgtaaggaatgtaactataaaacagtgagaaaagaTGATCTaatgaaacatgtaaaaatgcatactggtgaagaatataagtgtaaggaatgtgattataaaacagtttggaaacaCAGTCTAGAGGCAcatctgaaaattcatactggtgaagaatataagtgtaagaaatgtgattataaaacggtttgGAAACAGAGACTAtttgaacatgtaaaaattcatactggtgatgaatataagtgtaaggaatgtaactataaaacagttagaaaagataatctaaagaaacatctgAAAATTCATGCTGGcgaaaaatataagtgtaaggaaggTAACTATAAAACAGCGAGAAAAGATAGTTTAAAGAAACATcctaaaattcatactggtgaagaatataagtaa
Protein Sequence
MDVDNNESNPVKTEVIVKETFLFCEKYEVYNKNVQYFCKECNINTWFACSIKEHFRIHNSVACRHTTKSCTFKRPQLKTPLKGRLKAHVKNRTGEEYKCKECDYKTQWKRSLKEHARIHTGDQYKCKECDYKTVWKQSLEAHLKIHTGDEYKCKECDYKTTTKRCLKEHVRIHTGDQYKCNECDYKAVWKQSLQAHLKIHTGEEYKCKECDYKTVRKLRLIEHIQIHTGDEYKCKECNYKTVRKNDLKKHIKIHTGEEYKCKECDYKTIWKQRLIEHIQIHTGDEYKCKECNYKTVRKDSLKKHLKIHIGEKYKCKECNYKTVRKDDLMKHVKMHTGEEYKCKECDYKTVWKHSLEAHLKIHTGEEYKCKKCDYKTVWKQRLFEHVKIHTGDEYKCKECNYKTVRKDNLKKHLKIHAGEKYKCKEGNYKTARKDSLKKHPKIHTGEEYK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-