Basic Information

Gene Symbol
hang
Assembly
GCA_013368075.1
Location
JABVZV010002352.1:5118603-5165698[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 19 0.67 9.5 7.0 2.1 2 19 200 217 200 222 0.92
2 19 1.5 22 5.9 2.7 1 20 329 348 329 350 0.94
3 19 3.4 49 4.8 0.9 1 19 438 456 438 461 0.90
4 19 0.00036 0.0051 17.3 1.4 3 23 561 582 559 582 0.95
5 19 1.4 20 6.0 1.5 2 23 590 612 589 612 0.90
6 19 0.24 3.4 8.4 0.1 1 23 629 651 629 651 0.98
7 19 0.005 0.071 13.7 0.2 3 23 656 676 655 676 0.97
8 19 7e-05 0.00099 19.5 3.1 2 23 700 721 699 721 0.94
9 19 2.6 37 5.2 0.2 2 23 778 799 777 799 0.96
10 19 4.2e-05 0.00059 20.3 6.6 1 23 834 856 834 856 0.98
11 19 0.88 12 6.7 1.8 3 23 880 900 878 900 0.97
12 19 7.3e-05 0.001 19.5 0.8 1 23 918 940 918 940 0.98
13 19 0.029 0.41 11.3 0.1 2 23 954 976 953 976 0.95
14 19 0.0012 0.017 15.7 0.3 1 23 992 1014 992 1014 0.94
15 19 0.053 0.75 10.5 1.0 1 23 1047 1070 1047 1070 0.95
16 19 0.018 0.25 12.0 1.3 2 23 1081 1102 1080 1102 0.97
17 19 3e-05 0.00042 20.7 0.3 1 23 1113 1136 1113 1136 0.97
18 19 4.6e-05 0.00065 20.1 3.2 1 23 1142 1164 1142 1164 0.99
19 19 0.0098 0.14 12.8 0.1 1 23 1185 1208 1185 1208 0.95

Sequence Information

Coding Sequence
ATGAGTGAACGCAGGTGGGGCAATTTTAGCTCCTGCTGTAGATTATGTTTGTCGGAAAAGTTGGGTACGTTGAAGTCCATTTTTGAGGATCCAATACATAGCAAAGATATCGTAGTTAATATTCATGAATGCGTTGGAGTCGAAgtTAAACCAAATGACAAATTATCCACAATGATTTGTGATAAGTGTTCAACACAAGTAAGTTCTTGGCGGAATTTCAGAGATATATCTTATGATAATCAATCGAAATTGGTGGGATGGCTGAACGACTGGAATTCCAATAATTGTATTGAGGAGTTGAATACGaaTATAAGAATTAAACATGAAGTGCTTGATGAACCAGAAAATGGGGCTGCACATCATGCTGATGAAGATGGCAATgaGGTACATGTTAAAACTGAACCCATTGAAGCTATATATCATGTTGAAACGGAGATGGGAGGTGAAGATTTATATGAATGTCCGCCAGCACTTACTCCCGAACATCTTATAGAAACATCATTTGTCCCCGCTGAAATGGAAATAGACGGTagcattaatttaataaatggaaATGgGAGAGACAGGCCGCCAGACGTTACTGCTGTTGATGGTAGAAAATGTTTCATGTGTAATAAAAGTTTCTCTAGCGTTGGTAATAAACACAGGCATGATGCAGTCTTTCATCGAGgcactaaaagaaaatacgaaggaaaagCAAAAGATTCAAGAAAGATAGTTACTGAACATCTACTAAATGGCGAAGTTGAACTTCAAAAGATTCAGTTTGCAGCAGGACTACAATTGCAGCAAAAATCAGCAAACTCCGAAGAAGTTGCATTAGAAGATATGAAGTTAACTAAGGTAGAAGAAAGCTATTTagataaatgtaaaacattggTGTCCATGACTGATACGCTAACCTGTGTTTGTCACAATGATAAGTTTGCTAATGCAAAGGATCTTcacatacatttaaaaaaacaaaaacaatggttTGCGATGTTTACTTGCTACAATTGCTTAATTACGTTTACAGAAAGGTCTTCGTATATGAAGCATTTTTGCGCTTGCACTAAAgatttattgcataatttaaGGCGTTTAACAGAATCACCGTTGAATCCAGAAATTAAAATGCGATTGTATCAAAATTACAAATGCATCAGGTGTAGTTGCATCTTTGCTTTCTACGAAGATTTCTGTAGTCATTTTGATGTTGAGCATATGGAAATATTACAAAGTGCTTCGCCGTTCAtatgtttttgttctaaaagTTTTGAAGAAATGGAGGATTATAAGCAACATTTGCACATATCATGCTTTTTGCGATATTTCTGTGATGTTTGTTTTGGAGTGTTTATCAGTGCCGatgaatttaaaattcattGTGAGAGTGAACACGATCATTCTGAACCTGGCAATTTATTGCCTTATGATCCTTTGATTAAACAGAAATCATCAGTTGGGTTGCTTCATCCAAGACGATCTCTGCCTCtcgaaaataatataaaaagggAGAGAGATGAACCTCGGGCGATGACCAGACGTAGAACCATTAACTTACCTAATATGCCATCATCCGAAAATTCGAGTCAAATCTCTGAAACAATTCCTGATTTGGAAGATGATCCTGATTATGAACCGGAACAGCCGGTGATTATTTCACCACAAACTGTGAAATCAGCAACTCCTACGGCTTGTCCACAGTGTGGCAAGGTGTACTCAACCTATCATAACATGTTGCGCCATTATAAATTATCTCATGATCAAAGTGGGAGAAttcttaaatgtaaatattgtaagagTAGATTTAGACTTATTactgaattaaaagaacacgAAGTGAAATATCATGAATGTGACACTGACAATGAGGCGAGCGATTCAgaaaaagtttgtaatttttcttgtcCAGAATGCAGGTCTCTATTTGCAGACGTGGAGAGCTGGACTGAACATATGAAGCAACATCCTAAAAAGGCTTGTGATCAGTGTGATAGAGAATTTGTTACGCAAACTGAATTGGATCAACATAGAAGTGTGCACTTGAATATTAAACTGTATAGAGATTCAGaaacaaaagattataaaaGCGAAATGGTTAGTCCATTACTTATTTGTCAGACGTGTGATAAAACATTCTCAACAAAAAGTGAATTACGCCACCATAAATTACTACATGAGAAAATGCCGGTGCTCAGTGTTCAAGATGGCAGTGAGCATGACGAAAAAGTCGATCTTAGCAAAAAATTTAGCTGTATTCCTTGTGGCAAACATTACGTTAGTTATGGAGGAATTTGGGATCATAATAAGAAGCATCATCCTAATAAAAATGCACAGTATCCTAAAGAATGCCCATTATGTTTCAAGCTATTGTCATCACGAGGGGCTTGGGTAAATCACGAAAAAATGCATGAACGACTGCTTAATATGAAAGAAGATATTGACGACGAGATAAGTAtacaaaaagtaattaagtataAGTCCATAAAGacagatgatgatgatgagtCATATCATACTTGTAAAAGGTGCTTTAAGGTATTTTCTAGTAAGTATAATCTTAAAAACCATATGAAGTCGCATGGTATTAATGTGAATCCTAGTAGTAGTAGGAGTAGTACAAAAACTgggaaaatcattaaaacatATTGGTGTAATATTTGCCATCAAGCATGTCCAGGATATTTTGAACTACAAGAGCATAAGCGTGAACATAAGATTCATGTTAATACCCAAGAAGAAGTTGAGGATAAGAAACCTgttatatttgaatgtaatgAGTGTTCCTTGACATTTACTACAAGTTTTGCATTGGCTAGACATCAAGAAAAACATGTTAAAAAACTGGAGTCGCCTCAAAAGTTAATATCAGTGTATTGCAAGTATTGCAAGGTACCATTCCCAAGTGTGATGGATTTGAACGAACATATGGATAAGGATCATAATGACATGGAATCAAAGCCAAAACTGCAACTGCCTAAAACGAAGCATACttgtaaattgtgtaaaaagGTGTTTGACAACGCAGGTGCTCTGGCTTCTCATCAAGGTTGGCATAAGAGAGTTAAATTTAATAGAGTTCGTGCTCAAGAacagttaatcaaatctttggGAAAACAGGCAAGGACACCATCACCTCAGCCTATCCATAAATATCCATGTCATTCTTGTTCTGCTCACTTTTCAAGCGACGCAAGTTTGCAAATTCATATATTAGAGACCCATCGTAATATCAATACAACTGTGTTGCTTATGAAATGTAACAGTTGCAAAATGAGTTTTGATAAGAAATCAGCGTTTGATATACATATGCAGTTGCATAAACAGGTTGAAAGTAAGACTCCAAAACCATACAGTTGCAAATATTGCCCTGCTGGTTTTAGTCGACCAGAAGCTTTGAATACACATATGAAACAGCAGCATAAAGAGTTTGTTGAATATAAATGTCACGAATGCGAACGTTCATTTGATAAACAAAATTCTCTCACTGTGCACTTAAAAATGCATGAGCGTCACAGGCTTTCTGGACAGACGGCTTCACCTAAGccaatacataataaaaacatttacttttgcTCTATTTGTGATTTAGGATTCTCTATAGCCAAAGATCTACGCAATCATGTAGTTACTGCACATCCTTTTTAA
Protein Sequence
MSERRWGNFSSCCRLCLSEKLGTLKSIFEDPIHSKDIVVNIHECVGVEVKPNDKLSTMICDKCSTQVSSWRNFRDISYDNQSKLVGWLNDWNSNNCIEELNTNIRIKHEVLDEPENGAAHHADEDGNEVHVKTEPIEAIYHVETEMGGEDLYECPPALTPEHLIETSFVPAEMEIDGSINLINGNGRDRPPDVTAVDGRKCFMCNKSFSSVGNKHRHDAVFHRGTKRKYEGKAKDSRKIVTEHLLNGEVELQKIQFAAGLQLQQKSANSEEVALEDMKLTKVEESYLDKCKTLVSMTDTLTCVCHNDKFANAKDLHIHLKKQKQWFAMFTCYNCLITFTERSSYMKHFCACTKDLLHNLRRLTESPLNPEIKMRLYQNYKCIRCSCIFAFYEDFCSHFDVEHMEILQSASPFICFCSKSFEEMEDYKQHLHISCFLRYFCDVCFGVFISADEFKIHCESEHDHSEPGNLLPYDPLIKQKSSVGLLHPRRSLPLENNIKRERDEPRAMTRRRTINLPNMPSSENSSQISETIPDLEDDPDYEPEQPVIISPQTVKSATPTACPQCGKVYSTYHNMLRHYKLSHDQSGRILKCKYCKSRFRLITELKEHEVKYHECDTDNEASDSEKVCNFSCPECRSLFADVESWTEHMKQHPKKACDQCDREFVTQTELDQHRSVHLNIKLYRDSETKDYKSEMVSPLLICQTCDKTFSTKSELRHHKLLHEKMPVLSVQDGSEHDEKVDLSKKFSCIPCGKHYVSYGGIWDHNKKHHPNKNAQYPKECPLCFKLLSSRGAWVNHEKMHERLLNMKEDIDDEISIQKVIKYKSIKTDDDDESYHTCKRCFKVFSSKYNLKNHMKSHGINVNPSSSRSSTKTGKIIKTYWCNICHQACPGYFELQEHKREHKIHVNTQEEVEDKKPVIFECNECSLTFTTSFALARHQEKHVKKLESPQKLISVYCKYCKVPFPSVMDLNEHMDKDHNDMESKPKLQLPKTKHTCKLCKKVFDNAGALASHQGWHKRVKFNRVRAQEQLIKSLGKQARTPSPQPIHKYPCHSCSAHFSSDASLQIHILETHRNINTTVLLMKCNSCKMSFDKKSAFDIHMQLHKQVESKTPKPYSCKYCPAGFSRPEALNTHMKQQHKEFVEYKCHECERSFDKQNSLTVHLKMHERHRLSGQTASPKPIHNKNIYFCSICDLGFSIAKDLRNHVVTAHPF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-