Basic Information

Gene Symbol
-
Assembly
GCA_013368075.1
Location
JABVZV010000380.1:1365927-1368639[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 24 0.36 5.1 7.9 1.4 1 23 98 120 98 120 0.97
2 24 0.025 0.36 11.5 1.5 1 23 152 174 152 174 0.97
3 24 0.0047 0.066 13.8 1.2 1 23 219 241 219 241 0.99
4 24 6.1e-05 0.00087 19.7 1.9 1 23 246 268 246 268 0.98
5 24 2.6 37 5.2 4.0 1 23 273 295 273 295 0.97
6 24 0.051 0.73 10.5 2.6 1 23 300 322 300 322 0.98
7 24 0.01 0.15 12.7 2.0 1 23 327 349 327 349 0.98
8 24 0.017 0.23 12.1 1.4 1 23 354 376 354 376 0.98
9 24 0.01 0.15 12.7 2.0 1 23 381 403 381 403 0.98
10 24 0.087 1.2 9.8 3.1 1 23 408 430 408 430 0.98
11 24 0.0017 0.024 15.2 4.0 1 23 435 457 435 457 0.99
12 24 1 14 6.4 1.8 1 23 462 484 462 484 0.94
13 24 0.00041 0.0058 17.1 1.6 1 23 489 511 489 511 0.99
14 24 0.00012 0.0017 18.8 0.8 1 23 516 538 516 538 0.99
15 24 5.8 82 4.1 0.3 5 23 540 558 539 558 0.93
16 24 0.01 0.14 12.8 3.4 1 23 563 585 563 585 0.98
17 24 0.01 0.15 12.7 2.0 1 23 590 612 590 612 0.98
18 24 0.087 1.2 9.8 3.1 1 23 617 639 617 639 0.98
19 24 0.0025 0.035 14.7 4.0 1 23 644 666 644 666 0.99
20 24 1 14 6.4 1.8 1 23 671 693 671 693 0.94
21 24 0.00041 0.0058 17.1 1.6 1 23 698 720 698 720 0.99
22 24 0.00012 0.0017 18.8 0.8 1 23 725 747 725 747 0.99
23 24 0.011 0.15 12.7 4.4 1 23 752 774 752 774 0.99
24 24 3 42 5.0 7.2 1 19 779 797 779 797 0.98

Sequence Information

Coding Sequence
ATGGATATCGACTCGTTAGAGTTTATTGAAAGTcgtgctataaaatcagaagtgattttaacagagacATTTCCTTTTTATGGGAAGTACGAAGatTGTGGGAGTAATGAACTGAAAGCAGAGCCAGTAAATTACGAAGAATCACTTAAATGTAAAGAAGGAAATGATCTGGCAGAACCCATAGATATACACGGTGCTCCGATGCAACAAGATTTTTGTGATGACTCTAATTTTACAACAATGGGAGAAAACTCTCAAATACAAGTTTTAAGAGTtaccaaaaacgttaaatttttctgtaaggaatgtaactttacaacccAGTTAGAAAGTTCTATAAAAGAGCATATGAAGATTCACAATGACaaatataatattgaagaatgtaattttaagatgcCACAGATTATTTCTCTATCGACACAGTTGAATACTCCAAGAAGCGagaatgaatatttttgtaatgaatgtaattacacaaCATTGAACAAAGATTATCTAATGAAACATGTGAAGATTCACAAAGGTACTTCATATAGTTGcgagaaatgtgattataatacacAGTGCCAAGGTCACTTTACAGCAGATGcaaaaattcattctggtgaACATtttctaaaggaacatctcaaaattcacactagcgaagaatataagtgtaaagaatgtgattataaaacaatatggaaaaataatctaaacagacatgttaaaattcatacaggcggtgaatttaagtgtaaagaatgtgattataaaacagtacaaaaatataatctaaatcaacatgtcaaaattcataccggtaatgaacataagtgtaacaaatgtgattataaaacaatatggaaaaagcttctaaaggaacatttcaaaattcatactggtgatgaatataagtgtgtggaatgtgattataagacaaAATGGAGAAATAATCTAAAGCATCATGccagaattcatacaggtgatgaatataagtgtaaagattgtgattataaaacaacatggaaaaatcttctaaaggaacatctcaaaatgcatactggtgaagaatataagtgtaacgaatgtgattataagacaaaatggaaaaatcttctaaaggaacatctcaaaattcatactggtaatgaatataagtgtaaagattgtgattataaaacaacatggaaaaatcttctaaaggaacatctcaaaatGCATAccggtgaagaatataagtgtaaagaatgtgattatgaaacgGTATGGAAACATCATCTAAacgaacatgtcaaaattcatactggtgaagaatataagtgtaatgaatgcgattataaaacaataaggaaacattttctaaaggaacatctcaaaattcatactggcgaagaatataagtgtaaagaatgtgattataaaacaatatggaaacatcTTATAAAGGAACATCTccaaattcatactggtgaagtatataagtgtaaagaatgtgattataaaacagtacgaaaaaGTCGGCTAAACGAACAtgtcaaaatacatacaggtgaacaatataagtgtaaagaatgtgattataaaacgatacGGAAAGgtgatctaatgcaacatgtcaaaattcatacagattgtgattataaaacaacatggaaaaatcttctaaaggaacatctcaaaatGCATAccggtgaagaatataagtgtaacgaatgtgattataaaacaaaatggaaaaataatctaaagcaTCATGccagaattcatacaggtaatgaatataagtgtaaagattgtgattataaaacaacatggaaaaatcttctaaaggaacatctcaaaatGCATAccggtgaagaatataagtgtaaagaatgtgattatgaaacgGTATGGAAACATCATCTAAacgaacatgtcaaaattcatactggtgaagaatataagtgtagtgaatgcgattataaaacaataaggaaacattttctaaaggaacatctcaaaattcatactggcgaagaatataagtgtaaagaatgtgattataaaacaatatggaaacatcTTATAAAGGAACATCTccaaattcatactggtgaagaatataagtgtaaagaatgtgattataaaacagtacgaaaaaGTCGGCTAAACGAACAtgtcaaaatacatacaggtgaacaatataagtgtaaagaatgtgattataaaacgatacGGAAAGgtgatctaatgcaacatgtcaaaattcatacaggtaataaatataagtgtaatgaatgtgattataaaacaacatggaaaaAGCATCTTAagcaacatctcaaaattcacattggtgatgaacataagtgtaaagaatgtgattataaaacagtatcgAAACATTGTCTAAAgcaacattaa
Protein Sequence
MDIDSLEFIESRAIKSEVILTETFPFYGKYEDCGSNELKAEPVNYEESLKCKEGNDLAEPIDIHGAPMQQDFCDDSNFTTMGENSQIQVLRVTKNVKFFCKECNFTTQLESSIKEHMKIHNDKYNIEECNFKMPQIISLSTQLNTPRSENEYFCNECNYTTLNKDYLMKHVKIHKGTSYSCEKCDYNTQCQGHFTADAKIHSGEHFLKEHLKIHTSEEYKCKECDYKTIWKNNLNRHVKIHTGGEFKCKECDYKTVQKYNLNQHVKIHTGNEHKCNKCDYKTIWKKLLKEHFKIHTGDEYKCVECDYKTKWRNNLKHHARIHTGDEYKCKDCDYKTTWKNLLKEHLKMHTGEEYKCNECDYKTKWKNLLKEHLKIHTGNEYKCKDCDYKTTWKNLLKEHLKMHTGEEYKCKECDYETVWKHHLNEHVKIHTGEEYKCNECDYKTIRKHFLKEHLKIHTGEEYKCKECDYKTIWKHLIKEHLQIHTGEVYKCKECDYKTVRKSRLNEHVKIHTGEQYKCKECDYKTIRKGDLMQHVKIHTDCDYKTTWKNLLKEHLKMHTGEEYKCNECDYKTKWKNNLKHHARIHTGNEYKCKDCDYKTTWKNLLKEHLKMHTGEEYKCKECDYETVWKHHLNEHVKIHTGEEYKCSECDYKTIRKHFLKEHLKIHTGEEYKCKECDYKTIWKHLIKEHLQIHTGEEYKCKECDYKTVRKSRLNEHVKIHTGEQYKCKECDYKTIRKGDLMQHVKIHTGNKYKCNECDYKTTWKKHLKQHLKIHIGDEHKCKECDYKTVSKHCLKQH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-