Basic Information

Gene Symbol
-
Assembly
GCA_013368075.1
Location
JABVZV010001931.1:2046846-2048564[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.42 5.9 7.7 0.0 1 21 68 88 68 89 0.94
2 16 0.0015 0.022 15.3 1.8 1 23 151 173 151 173 0.98
3 16 0.00054 0.0076 16.8 1.3 1 23 178 200 178 200 0.99
4 16 0.0063 0.089 13.4 1.4 1 23 205 227 205 227 0.99
5 16 0.0019 0.027 15.0 0.9 1 23 232 254 232 254 0.99
6 16 0.34 4.8 8.0 2.7 1 23 259 281 259 281 0.98
7 16 0.0009 0.013 16.1 0.9 1 23 286 308 286 308 0.99
8 16 0.004 0.056 14.0 0.9 1 23 313 335 313 335 0.98
9 16 0.019 0.28 11.9 1.3 1 23 340 362 340 362 0.99
10 16 0.0071 0.1 13.2 0.6 1 23 367 389 367 389 0.98
11 16 0.0009 0.013 16.1 0.9 1 23 394 416 394 416 0.99
12 16 0.0071 0.1 13.2 0.6 1 23 421 443 421 443 0.98
13 16 9e-05 0.0013 19.2 1.1 1 23 448 470 448 470 0.99
14 16 5.2e-05 0.00074 20.0 1.5 1 23 475 497 475 497 0.99
15 16 0.00034 0.0049 17.4 1.1 1 23 502 524 502 524 0.99
16 16 0.0075 0.11 13.2 0.8 1 23 529 551 529 551 0.98

Sequence Information

Coding Sequence
atggatgttgattctattgaaagttgtgcaataaaatctgaagtgattttaacagaaacttTTTCGTTTTGTGAACAATACGGAGGTTATGGGGGTAAAGAACTAAAAATAGAGCCCATAGATTgcgaagaatcttttaaatgtaaggaagaagATATTTCTGTAAAGCAAACAGATGTGCATTCTGCTCTGATGcaacaattttcttgtaatgagtgtGACTTTATAACAATGGGAAGagattctctaatagaacacttgaaaattactaaaaatgtcCAATATTCTTGTAAGGAGTGTAACTTTGCAACCCATTTACAATGTtccataaaaaaacattttgggATTCACAAAGAGTTAGATGATAAGTATATTATTGAAGCACGTAATTTTCAGAAATCACAGGATCCCTGTTTAACCGCACAGTGGAAAACAAAAAGTAGTGTCCACTAtacttgtaatgaatgtaattataccacattAAACCAAAGTTATCTAagaaaacatgtcaaaattcacacaggtgttgattataagtgtaaagaatgtgattataaaacagtgtggcaaagttccttaaagaaacatatcaaaattcatacaggagataaatataagtgcaAGGAGTGTGATTTTAAATCAACatggcaaagtagtctaaacgaacatgtcaaaactcatacaggtgttgaatataagtgtacagaatgtgattataaaacagtgtggcaaaataatctaaagcagcatatcaaaattcatacaggagataattataagtgtaaggaatgtaattttaaatcagcATGGCAATGtaatctaaaagaacatgtcaaaattcatacaggtgatgaatataagtgtaaagaatgtgattataaaacagcatggcaaagtagtctaaagcaacatatcaaaattcatacaggagataaatataagtgtaaggagtgTGATTTTAAATCAACGTGGCAAAGTAATCTAAacgaacatgtcaaaattcatactggtgttgaatataagtgtaaagaatgtgattttaaaacagtgtggcaaaatACTCTAAAGCAGCATATCAAAATTCACACGggagataaatataaatgtaaggagtGCGATTTTAAATCAGCATGGCAAAGTAATCTAagggaacatgtcaaaattcatacaggtgatgaatataagtgtaaagaatgtgattataaaacagcatggcaaagtagtctaaagcagcatatcaaaattcacacgggagataaatataaatgtaaggagtGCGATTTTAAATCAGCATGGCAAAGTAATCTAagggaacatgtcaaaatccatagaggtgacaaatataagtgtaaagaatgtgactataaaacaatacgaaaaggtagtctaaaggaacatgtcaaaattcatacaggtgatgaatataagtgtaaagaatgtgactataaaacagtacggaaaggtagtctaaagcaacatgtcaaaattcatacaggtgatgaatataagtgtaaggaatgtgattataaaacagtatggcaaagtaatctaaaacaacatatcaaaattcacacaggagatgaatataagtgtaaggaatgtgattttaaatcaGTAtggcaaagtaatctaaaggaTCATGTCAAAATCCATAGTGGTGACAAATaa
Protein Sequence
MDVDSIESCAIKSEVILTETFSFCEQYGGYGGKELKIEPIDCEESFKCKEEDISVKQTDVHSALMQQFSCNECDFITMGRDSLIEHLKITKNVQYSCKECNFATHLQCSIKKHFGIHKELDDKYIIEARNFQKSQDPCLTAQWKTKSSVHYTCNECNYTTLNQSYLRKHVKIHTGVDYKCKECDYKTVWQSSLKKHIKIHTGDKYKCKECDFKSTWQSSLNEHVKTHTGVEYKCTECDYKTVWQNNLKQHIKIHTGDNYKCKECNFKSAWQCNLKEHVKIHTGDEYKCKECDYKTAWQSSLKQHIKIHTGDKYKCKECDFKSTWQSNLNEHVKIHTGVEYKCKECDFKTVWQNTLKQHIKIHTGDKYKCKECDFKSAWQSNLREHVKIHTGDEYKCKECDYKTAWQSSLKQHIKIHTGDKYKCKECDFKSAWQSNLREHVKIHRGDKYKCKECDYKTIRKGSLKEHVKIHTGDEYKCKECDYKTVRKGSLKQHVKIHTGDEYKCKECDYKTVWQSNLKQHIKIHTGDEYKCKECDFKSVWQSNLKDHVKIHSGDK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-