Basic Information

Gene Symbol
-
Assembly
GCA_013368075.1
Location
JABVZV010001223.1:5531987-5533399[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 0.27 3.8 8.3 0.4 5 23 64 82 62 82 0.93
2 14 0.00072 0.01 16.4 1.3 1 23 87 109 87 109 0.99
3 14 2.8 40 5.1 6.1 1 23 114 136 114 136 0.98
4 14 3.5e-05 0.00049 20.5 3.0 1 23 141 163 141 163 0.99
5 14 0.2 2.8 8.7 2.3 1 23 168 190 168 190 0.98
6 14 0.0055 0.078 13.6 0.9 1 23 195 217 195 217 0.98
7 14 5.1e-05 0.00073 20.0 3.2 1 23 222 244 222 244 0.99
8 14 0.00018 0.0025 18.3 3.0 1 23 249 271 249 271 0.98
9 14 6.5e-06 9.2e-05 22.8 1.9 1 23 276 298 276 298 0.99
10 14 1.5e-06 2.1e-05 24.8 1.0 1 23 303 325 303 325 0.99
11 14 0.00012 0.0017 18.8 1.5 1 23 330 352 330 352 0.99
12 14 0.001 0.015 15.9 1.3 1 23 357 379 357 379 0.98
13 14 1.1e-05 0.00016 22.1 1.3 1 23 384 406 384 406 0.99
14 14 0.001 0.015 15.9 1.3 1 23 411 433 411 433 0.98

Sequence Information

Coding Sequence
ATGGATGCTGaatgtaatgaaagttatttgataaaatcggAAATAAAACAGGAAGTGGTTGTAAATGAGACATTCTCCTTTAgtggaaaatatgaagattataGAAGTGTAGAAAGTCTGGCAAATTGTAGAGCAGCTTTTAAACAGGAAAGAGGGATGGATATGGAGCACGCCAATACATCCAAATgtgaatgtgactttaaagcaGGGAGACAAGATACACTTAAAGCACACATCAGAaaccatactggtgatgaatttCAATgttatgaatgtaattataaaacaatgagGAAAGATAGACTAAACGCAcacatcagaatccatactggtaATGAACATAAGTGTggggaatgtgactacaaaacaccatggaaacagtgTTTTAAGAAACATATAAAACGGCATACTGGTGATTgctataaatgtaatgaatgtgactttaaaacagtgacaaaatttcatcttaaagcacacatcagaatccatactggtgatgagcataagtgtaaggaatgtgacttcAAAACACCATGGgaacagaattttataaaacatataaaaatgcaTACTGGTGATCGCTATAATTGTAACGAATGTGGCTTTCAAACAGCATGGAAAAATCATCTTAAAGCAcacatcagaatccatactggtgatgaatttaaatgtaatgaatgtgactttaaaacggtgacaaaatttcatcttaaagcacacatcagaatccatactggtgatgagcataagtgtaaggaatgtgattacaaaacagtaagGAAAGATCAACTTAAAGCACACAACAGAATCCATAgtggtgatgagtataagtgtaaggaatgtggcTACAAAACAGTAAGGAAAGATCAATTTAAAGCACACATCAGAAaccatactggtgatgagtataagtgtaaggaatgtgactacaaaacagtAAGGAAAGATCAACTTAAAGCAcacatcagaatccatactggtgatgaatttaaatgtaacgaatgtgactttaaaacagtgaggaaagatCGACTTAACACAcacatcagaatccatactggagatgaatttaaatgtaacgaatgtgactttaaaacagtgaggaaagatCGACTTACTGCACACAacagaatccatactggtgatgaatttaaatgtaacgaatgtgactttaaaacagtgaggaaagatCAACTTAACACAcacatcagaatccatactggagatgaatttaaatgtaatgaatgtgactttaaaacagtgaggaaagatCGACTTACTGCACATAacagaatccatactggtgatgagcATAAGTGTAAGGAACAAaaaaacaccatggaagcagaattttaa
Protein Sequence
MDAECNESYLIKSEIKQEVVVNETFSFSGKYEDYRSVESLANCRAAFKQERGMDMEHANTSKCECDFKAGRQDTLKAHIRNHTGDEFQCYECNYKTMRKDRLNAHIRIHTGNEHKCGECDYKTPWKQCFKKHIKRHTGDCYKCNECDFKTVTKFHLKAHIRIHTGDEHKCKECDFKTPWEQNFIKHIKMHTGDRYNCNECGFQTAWKNHLKAHIRIHTGDEFKCNECDFKTVTKFHLKAHIRIHTGDEHKCKECDYKTVRKDQLKAHNRIHSGDEYKCKECGYKTVRKDQFKAHIRNHTGDEYKCKECDYKTVRKDQLKAHIRIHTGDEFKCNECDFKTVRKDRLNTHIRIHTGDEFKCNECDFKTVRKDRLTAHNRIHTGDEFKCNECDFKTVRKDQLNTHIRIHTGDEFKCNECDFKTVRKDRLTAHNRIHTGDEHKCKEQKNTMEAEF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-