Basic Information

Gene Symbol
-
Assembly
GCA_013368075.1
Location
JABVZV010002186.1:1743648-1746711[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 31 0.1 1.4 9.6 0.2 1 19 68 86 68 89 0.94
2 31 0.0013 0.018 15.6 4.8 1 23 113 135 113 135 0.98
3 31 0.0067 0.095 13.3 1.0 1 23 140 162 140 162 0.98
4 31 0.013 0.18 12.5 3.9 1 23 194 216 194 216 0.97
5 31 0.0047 0.067 13.8 1.2 1 23 221 243 221 243 0.99
6 31 1.7 24 5.8 3.5 1 23 275 297 275 297 0.96
7 31 0.028 0.4 11.3 5.9 1 23 302 324 302 324 0.98
8 31 2.5 35 5.2 2.8 1 23 329 351 329 351 0.94
9 31 0.018 0.26 12.0 3.8 1 23 356 378 356 378 0.97
10 31 3.9e-05 0.00056 20.3 2.2 1 23 383 405 383 405 0.99
11 31 0.6 8.5 7.2 1.5 1 23 410 432 410 432 0.95
12 31 2.2 31 5.4 3.3 1 23 437 459 437 459 0.96
13 31 0.00022 0.0031 18.0 1.1 1 23 464 486 464 486 0.99
14 31 0.0093 0.13 12.9 2.6 1 23 491 513 491 513 0.99
15 31 5.8 82 4.1 3.0 1 23 518 540 518 540 0.93
16 31 0.018 0.26 12.0 3.8 1 23 545 567 545 567 0.97
17 31 3e-05 0.00043 20.7 2.0 1 23 572 594 572 594 0.99
18 31 1.4 20 6.0 1.6 1 23 599 621 599 621 0.94
19 31 2.2 31 5.4 3.3 1 23 626 648 626 648 0.96
20 31 0.015 0.21 12.3 1.1 1 23 653 675 653 675 0.98
21 31 0.00031 0.0044 17.5 0.9 1 23 680 702 680 702 0.99
22 31 0.00093 0.013 16.0 4.3 1 23 707 729 707 729 0.98
23 31 0.012 0.17 12.5 3.1 1 23 734 756 734 756 0.99
24 31 0.0046 0.065 13.8 3.5 1 23 761 783 761 783 0.98
25 31 9.9 1.4e+02 3.3 3.1 1 23 788 810 788 810 0.90
26 31 0.2 2.8 8.7 3.5 1 23 815 837 815 837 0.97
27 31 0.00022 0.0031 18.0 1.1 1 23 842 864 842 864 0.99
28 31 0.0093 0.13 12.9 2.6 1 23 869 891 869 891 0.99
29 31 0.2 2.8 8.7 3.5 1 23 923 945 923 945 0.97
30 31 3.6e-05 0.00051 20.5 2.6 1 23 950 972 950 972 0.99
31 31 0.026 0.37 11.5 1.4 1 23 977 1000 977 1000 0.97

Sequence Information

Coding Sequence
atggatTATGATTATAATGAAAGTTACCCGATGAAATCAGATGTAACTCTACAGGAAACATTTTCCTATTGCGGAAATTATAAAGATGATGAGAATGGAGACTTGAAAACGGACCTGATAAAgatagaaaaacattttaaatacgaagaaGAGGATAATCGGGGGAAGCTCACCGTTGTGTGTGTTGTACCCATACATCAATATagttgtaatgaatgtaattttgttacaaCAGAGAAAGATTCTTTAATAGAACACTTCTCTGTAGCACCATTAAGTGGTATCAAACGTATTTGTAAGGAAAgtgtttataaaacaaaacagaaagcGAATGAGTATAAGTGCaaggaatgcgattataaaacacgaAGGAAATATTGTCTAAAGGGACATATGttaattcatactggtgatgaatatacatgtaaagaatgtgattacaaaacgccatggaaatataatctaaaggaacatttaaaaattcataccggcgaagaatataagtgtaaggaatgtgattttaaaacactatggaaacagagtctaaagacacatttaaaaattcatactggtgataaatataagtgtaaagattgtgattataaaaccttacagaaaagtcatctaaaggaacatagattaattcacactggtgatgaatataaatgtaaagaatgtgattataaaacaccatggaagtataatctaaaggaacatttaaaaattcataccggcgaagaatataagtgcaaggaatgtgattttaaaacactatggaaacagagtctaaagacacatttaaaaattcatactggtgataaatataagtgtaaagagtgtaaTTATAAAGCCTTACATAAAAGTCGCCTAAAGGAACATAGAttaattcacactggtgatgaatatacatgtaaagagtgtgattataaaacaacatgcaaaagttatctaaagaaacatttaaaaattcacaccggtgaagaatataagtgtaaggaatgtgattttaaaacattatggAAAGAGAGTCTAAAGACACATTtaagaattcatactggtgatgaatataagtgtaaagaatgtgattataaaaccttACAGAAAAGTCACCTAAAGGAACATAGAttaattcacactggtgatgaatataaatgtaaagagtgtgattataaaacaccaaggaaatataatctaaagcaacatgtaaaaattcataccagtgaagaatataagtgtaaggaatgtgattttaaaacactatGGAAAGACAGTCTAAAGACACATTtaagaattcatactggtgatgaatataagtgtaaagtatGTAATTATAAAGCCTTACATAAAagtcgtctaaaggaacatagattaattcacactggtgatgaatataaatgtaaagagtgtgattatataACACCATACAAAagttatctaaaggaacatttaaaaattcataacggcgaagaatataagtgtaacgaatgtgattataaaacaacatggaaaaataattttaataaacatttaaaaattcataacggcgaagaatataagtgtaaggaatgtgattttaaaacattatggAAAGAGAGTCTaaagacacatttaaaaattcatactggtgatgaatataagtgtaaggaatgtgattataaaaccttACAGAAAAGTCACCTAAAGGAACATAGAttaattcacactggtgatgaatataaatgtaaagagtgtgattataaaacaccaaggaaatataatctaaaggaacatttaaaaattcataccagtgaagaatataagtgtaaagaatgtgattttaaaacactatGGAAAGACAGTCTaaagacacatttaaaaattcatactggtgatgaatataagtgtaaagtatGTAATTATAAAGCCTTACATAAAagtcgtctaaaggaacatagattaattcacactggtgatgaatataaatgtaaagagtgtgattataaaacaccatggaagtataatctaaaggaacatagattaattcacactggtgatgaatatacatgtaaagagtgtgattatataACACCATACAAAagttatctaaaggaacatttaaaaattcataacggcgaagaatataagtgtaacgaatgtgattataaaacacgaaGGAAATATTGTCTAAAGGGACATATGttaattcatactggtgatgaatataaatgtaaagaatgtgattataaaacaacatggaaaaataattttaataaacatttaaaaattcatactggtgataaatataagtgtaacgaatgtgattataaaaccttacagaaaagtcatctaaaggaacatttaaaaattcataccggcgaagaatataagtgtaaggaatgtgattttaaatcaCTATGGAAAGAGAGTCTaaagacacatttaaaaattcatactggtgataaatataagtgtgaaaaatgtgattataaaaccttACATAAAAgccttctaaaggaacataaattaattcacactggtgatgaatataaatgtaaagagtgtgattatataACACCATACAAAagttatctaaaggaacatttaaaaattcataacggcgaagaatataagtgtaacgaatgtgattataaaacaacatggaaaaataattttaataaacatttaaaaattcataccggtgaaGAATATaactgtaaggaatgtgattttaaatcaCTATGGAAAGAGAGTCTaaagacacatttaaaaattcatactggtgataaatataagtgtgaaaaatgtgattataaaaccttACATAAAAgccttctaaaggaacataaattaattcacactggtgatgaatataaatgtaaagagtgtgattataaaacaacacgCAAAAGTTATCTAAacgaacatttaaaaattcataccggcgaagaatataagtgtaacgaatgtgattataaaacagtgtggacaagtaatttaaaaagtcaTGTGCGTAATAAACATCTAAAACTCtaa
Protein Sequence
MDYDYNESYPMKSDVTLQETFSYCGNYKDDENGDLKTDLIKIEKHFKYEEEDNRGKLTVVCVVPIHQYSCNECNFVTTEKDSLIEHFSVAPLSGIKRICKESVYKTKQKANEYKCKECDYKTRRKYCLKGHMLIHTGDEYTCKECDYKTPWKYNLKEHLKIHTGEEYKCKECDFKTLWKQSLKTHLKIHTGDKYKCKDCDYKTLQKSHLKEHRLIHTGDEYKCKECDYKTPWKYNLKEHLKIHTGEEYKCKECDFKTLWKQSLKTHLKIHTGDKYKCKECNYKALHKSRLKEHRLIHTGDEYTCKECDYKTTCKSYLKKHLKIHTGEEYKCKECDFKTLWKESLKTHLRIHTGDEYKCKECDYKTLQKSHLKEHRLIHTGDEYKCKECDYKTPRKYNLKQHVKIHTSEEYKCKECDFKTLWKDSLKTHLRIHTGDEYKCKVCNYKALHKSRLKEHRLIHTGDEYKCKECDYITPYKSYLKEHLKIHNGEEYKCNECDYKTTWKNNFNKHLKIHNGEEYKCKECDFKTLWKESLKTHLKIHTGDEYKCKECDYKTLQKSHLKEHRLIHTGDEYKCKECDYKTPRKYNLKEHLKIHTSEEYKCKECDFKTLWKDSLKTHLKIHTGDEYKCKVCNYKALHKSRLKEHRLIHTGDEYKCKECDYKTPWKYNLKEHRLIHTGDEYTCKECDYITPYKSYLKEHLKIHNGEEYKCNECDYKTRRKYCLKGHMLIHTGDEYKCKECDYKTTWKNNFNKHLKIHTGDKYKCNECDYKTLQKSHLKEHLKIHTGEEYKCKECDFKSLWKESLKTHLKIHTGDKYKCEKCDYKTLHKSLLKEHKLIHTGDEYKCKECDYITPYKSYLKEHLKIHNGEEYKCNECDYKTTWKNNFNKHLKIHTGEEYNCKECDFKSLWKESLKTHLKIHTGDKYKCEKCDYKTLHKSLLKEHKLIHTGDEYKCKECDYKTTRKSYLNEHLKIHTGEEYKCNECDYKTVWTSNLKSHVRNKHLKL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-