Lhir023090.1
Basic Information
- Insect
- Lagria hirta
- Gene Symbol
- Rreb1
- Assembly
- GCA_947359425.1
- Location
- OX375795.1:17647292-17652093[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 15 1e-05 0.0005 21.1 1.0 1 23 55 77 55 77 0.99 2 15 0.00026 0.013 16.6 0.5 1 23 90 112 90 112 0.98 3 15 0.00033 0.017 16.3 6.1 1 23 118 140 118 140 0.98 4 15 7.1 3.6e+02 2.7 0.5 2 21 201 221 200 224 0.74 5 15 0.00056 0.028 15.6 2.1 2 23 230 252 230 252 0.97 6 15 0.14 7.3 8.0 0.1 1 23 454 476 454 476 0.96 7 15 1.6e-05 0.00082 20.4 0.8 1 23 485 507 485 507 0.99 8 15 0.0017 0.084 14.1 3.1 1 23 513 536 513 536 0.97 9 15 0.00099 0.05 14.8 3.0 1 23 910 933 910 933 0.97 10 15 0.0011 0.056 14.6 0.5 2 23 1151 1172 1150 1172 0.97 11 15 0.25 13 7.2 6.3 1 23 1178 1201 1178 1201 0.97 12 15 0.27 14 7.1 4.6 1 20 1229 1249 1229 1253 0.95 13 15 0.35 17 6.8 0.5 1 23 1306 1329 1306 1329 0.93 14 15 0.033 1.7 10.0 0.4 3 23 1376 1396 1374 1396 0.93 15 15 0.00072 0.036 15.2 4.7 1 23 1402 1424 1402 1424 0.98
Sequence Information
- Coding Sequence
- ATGGACGCATCATCAGATTTTAACCAAGCAGCCAAAGAAAATCTTTTAAACCAAAGTATCCAAAGCGACTCTGGAGTGTTTTCTGCAACGAATAACTCAAATATCGGCACCGAAAACGGTGATTCCGACACCAGAAGCGAATGCAGCACTCCTGAAAGAAGATATGTTTGTCCCATTTGTGACAAAATGTTGACTTCTCAACATGATTTTACTCTTCATATTCGATCTCATAACAACGATAACGAAATTCAAGAAAGTGATAAAGGCTTTACATGCAAAATTTGTTTCAAAGTTTTAAGCTCAAATTCGAGCTTAGATCGACATGTTTTGGTTCACAGCGGAGAAAGGCCTTTTCACTGTAGATATTGTGGAGATTCATTTACAACAAATGGCAATATGCACAGACATATGAGAACGCACAACCAAAAAAATGATAGTTATGAATCTGACGAAAGTGACAGCAACGTCAGTGGTAGTTCCAAAAGCACAGAATTTAACAACAATAAAATTGAATCTAAAAAAAGAAAACTGGAACATGAAAATGAAGTAAAGAAGAAAGTTAAGAGTTGTAGTGACAGCGAAGATGCCACTTCATTTTGTAGATGTCCAGTATGTGATAGAACTGATTTTGACTCAACTATTGCTTTAGAGACTCACTTAGAAGATAATCATCCTGATTATCCAGCGAAATGCAATCAATGCAACAAAATCTTCCAAAATAACAAACAACTCACTATTCATCGTAGCACTGTACATGTGCAATCTAAAACACATACAGTGTCTGGTTTTAAAGATCTAACATTTGTTGATTTTTCAAGCAAAAAGTTCCCCCATATTGCACGATATGAATGTGAAAAAAATCTACATACAGCTTCCGAAGGTTTGAACTTTCAATGCAGAGCTTGTTTTAGAGCTTTTCCTTGTAGTACATCGTTAGAAATTCATGAGAAGGAATGCACGTTCAACTCTTCCAGCAATGGAATTGATTTGAGCAAACCAAATCAAGTTTCTGATACTGATATACGCCGAAACGAGTTTTTCTCAATTTTGCATCTTCAGGATAATTCTCCAGAAAAATTAATTCCTCAAACTTTAAAACATGAATCTTCTACCAAGTTGCGTCAGCAACTACTAGCAAAAGTTATGACTAATGACTCTAGTAAAGACTTAGCAGATATTCAAACTATTATTTCTATGACTACAAATGGAAGTCTTTTACAACATCTTCAAACTAAAACAGACCTAGGAATTTCTCCCAAAAACTTAGACATGTCCCAAGACATCAACCGTTCAGAACAAGAAGAAGAATCTCAAGATATTTTTGCTGTAGAATTTAGAAAGATGAAACTTCGAGGCGAGTTTCCGTGTCGATTATGTACGGCAGTTTTTCCAAACTTGAGAGCTTTAAAAGGTCATAACAGAGCTCACCTTAACGGCAATAGTAATGGTATGTACAGATGCAATATGTGTCCACATTCTTCCATAGATAAAGCGGCTTTAATAAGACATATGCGAACTCATAATGGTGACAGACCTTATGAATGCTCTCTTTGTAATTATGCTTTTACAACTAAAGCAAACTGTGAACGCCATTTAAGAAATAGACACGCTAAAACAACTCGAGAAGAAGTAAAAAAATCTATTATCTATCATCCTTCAGAAGATCCAACTAATGAAGAATTAAACAAATTAGCTCATAAAGACGATATTAGAAGACCTGTAATGTCTAACAATGAATCGCCTGAAAAAAGTCATTGCACTACTCCAAAAATCTCAGATTTGCGTAATTTTTCCTCTGAGATAAACAAACAAGAACTGATTCCACCTTTGATTCCTAGTTTACTAAAAGAGAGTCTTCATATAGATGCCCCCAAAACATACTCGAATATAACTAATATTATTCGAAATGAAAATCTAAAGACTTTCAAAGATCACAGAATGCAAACTGAGCAACTATCTCCATATATCCCCACTAACTACAACTTTTCACCAAAATCGTCAAACGTATCGACACCGCATAATCTTTCATCAAAAATACATGTAAAAAATCTACAAGAATTAAAAGAAAATTTCAATTATGATCAACATTCAGATGACGAGCCTTCTATACAAGAAGAAGAAGAGGAAGAAGAGCCAATGGATTTGAGCAAGAAAAGTAACGACAAAGATTTCAAAGATGATTTTTTGCCAGAAGATCTTTCTAAGAAAGCCCCAATTAGTCCATTAAATGTACGTGAACTTTTTACACAACAGCTATTAAAAAGTTCACCAAAGATTGATCCAGCTGCATGGTATGCTAGCCAACTTGCACTTTACAGAAACAGTTTCCCAGGATTCACAGGCTGGCCTGGGCTTCCAATAAATCCACTATTGTTTCCATCTTTGCAAGCTCCCTTATTACCACAAGAGTCCCAAGAAATGAAAGATCGTCTTCAAAGATTGCAGCTGGCAAGCGGCGGGTCCTTGATTGCAGACAGTTTTACAGATCGTTTAAAAAATTTTAAAACCGAAATCAAATCCGAAAATGTTTTTCCTCCCAGCGAAAATATTCAATCGCCATCTCTAAGTATTGATCCTAATTATGGAGATAATTTTAATGCTTTACACAGTCCAGTTGCCCAAAACAAACTTGATTTACAACATTCGCCAAATTCTGTTAAAATGGTAATTAAAAACGGCGTGCTAATGCCTAAACAAAAACAAAGACGATATAGAACTGAACGACCTTTCACTTGCGAACATTGCTCCGCAAGATTTACTTTGCGCTCTAATATGGAACGCCATATCAAGCAACAGCATCCACAATTTTGGTCACAACGCCAAAGAGGACATATTTCCAATCCCGGCAGAAAAAGTCAATCTAACATGAAACCAAATTATTGTGATCTTAGCATACCAAACTTCGAAATATCAAAATCACAAGACTTTGACGAAACCAAAGAACCGATCGACGAAAAACTAAAATACGCCTTATTAGCACAGCATTTGCAATCAAATCAATTAAACATGAATTTAGATATTAAGAAAGAAGATGACGATGACGGTGCATTAGTTATTGATGAACATGTTGATAAAGAACTTAAGACTGATGATTTTAACCAAAGATATGAAATAACACAGCGCACGAGAATTTTAGAAGAAAAGTTAAAAGAGTTGCATGCAAGACAAATGAAAATTGAAAACAAAGCCAAGCATGAGGAAAATCAAGATCTGGTACCTGTTTCTCGTTTGCTAGACAATGCATCTCAGCAGCAATTTAAAGAATATTTTAAAAGAGACAACGAAGAACCAGAAATAGGTGGAGCGAGTGAAGAAGATGAAGAAGGACTTGTTGCTAGCGGAAGTACTAGCGAAAGCAATGCTTCAGGAAATGAAGAAAATAAATGTGAGTCGGAAACTGTAGCACCTGTCAAGAAAAAATCGGCTTATTCAATGGCACCAAACCGTGTGAGTTGTCCATTTTGTAGTCGTAAATTTCCATGGAGCTCGTCTTTACGTCGACATATACTAACTCATACTGGTCAAAAACCATTCAAGTGCAGTCACTGTCCTCTCCTTTTCACGACAAAGTCAAATTGTGATCGGCATTTATTGCGAAAGCATGGTAATAATGCTACTACAATATCAAATGATGCAGTTACTAATAATACTAATTACATGATGAGAAATGTTCCCGAAAGACCGTTTAAATGTTCTAATTGTCCAAGTAGCACTTTTTCTACATATTCCAATTTGAAAAAGCATATTAGTTGCAAACATTCAAGTAACTCTCCAGACGATATTAAAGGATACGAAGGTGGAAGTTCCGAAGACGAAAAACTTCCATCAAATGGGGAACTCAAAGTAGAATGGGATAATCACTCCGGCAAACCTCTCAATGAAAATATGGGCGCTGTGCAGAATTCTGATTTGCCTTTTAAATGCCATTTATGTGATGGGTCTTTTGCAGAACGAGAAGTAGCTTTGAAGCATATTAAAGAAAATCATTATGCCGAATTTGATTTACTCATATCTAAAAATGCTCTTGATACAAATGCTACAACACCTGATGACAATGGTCATCATGAAGATGAGGACAACGAAATGCGAGGAAAATTTCCAGATTACTCAAACAGAAAAGTGATATGTGCTTTTTGTATGCGAAGATTTTGGTCTGCAGAGgatttacgaaggcacatgcgtactcatacaggagagagaccttttagttgcgatatatgcggcagaaaatttacactaaaacatAGTATGCTACGTCATCGAAAGAAGCATAATATTAACATGGATAGTGAGATTATAAACAGTGATGAAGATATTAATGGAGCTCCAACTCTTGAAAAGTTTACAAAACATGATAATATTCTTAATATGATGAAAGATAAAACAGATGAGTCTGATGGAAATGAAGGAAGTGATCTAATTAGTAATTTATTAGGAATTAGAGATAGATCGTTTATTGATAAGGTGTTAACAGCTTCTGCTGATGATGCCGCTAAACTACTAGGGGTTAAAAATGGAATAAGAGAATAA
- Protein Sequence
- MDASSDFNQAAKENLLNQSIQSDSGVFSATNNSNIGTENGDSDTRSECSTPERRYVCPICDKMLTSQHDFTLHIRSHNNDNEIQESDKGFTCKICFKVLSSNSSLDRHVLVHSGERPFHCRYCGDSFTTNGNMHRHMRTHNQKNDSYESDESDSNVSGSSKSTEFNNNKIESKKRKLEHENEVKKKVKSCSDSEDATSFCRCPVCDRTDFDSTIALETHLEDNHPDYPAKCNQCNKIFQNNKQLTIHRSTVHVQSKTHTVSGFKDLTFVDFSSKKFPHIARYECEKNLHTASEGLNFQCRACFRAFPCSTSLEIHEKECTFNSSSNGIDLSKPNQVSDTDIRRNEFFSILHLQDNSPEKLIPQTLKHESSTKLRQQLLAKVMTNDSSKDLADIQTIISMTTNGSLLQHLQTKTDLGISPKNLDMSQDINRSEQEEESQDIFAVEFRKMKLRGEFPCRLCTAVFPNLRALKGHNRAHLNGNSNGMYRCNMCPHSSIDKAALIRHMRTHNGDRPYECSLCNYAFTTKANCERHLRNRHAKTTREEVKKSIIYHPSEDPTNEELNKLAHKDDIRRPVMSNNESPEKSHCTTPKISDLRNFSSEINKQELIPPLIPSLLKESLHIDAPKTYSNITNIIRNENLKTFKDHRMQTEQLSPYIPTNYNFSPKSSNVSTPHNLSSKIHVKNLQELKENFNYDQHSDDEPSIQEEEEEEEPMDLSKKSNDKDFKDDFLPEDLSKKAPISPLNVRELFTQQLLKSSPKIDPAAWYASQLALYRNSFPGFTGWPGLPINPLLFPSLQAPLLPQESQEMKDRLQRLQLASGGSLIADSFTDRLKNFKTEIKSENVFPPSENIQSPSLSIDPNYGDNFNALHSPVAQNKLDLQHSPNSVKMVIKNGVLMPKQKQRRYRTERPFTCEHCSARFTLRSNMERHIKQQHPQFWSQRQRGHISNPGRKSQSNMKPNYCDLSIPNFEISKSQDFDETKEPIDEKLKYALLAQHLQSNQLNMNLDIKKEDDDDGALVIDEHVDKELKTDDFNQRYEITQRTRILEEKLKELHARQMKIENKAKHEENQDLVPVSRLLDNASQQQFKEYFKRDNEEPEIGGASEEDEEGLVASGSTSESNASGNEENKCESETVAPVKKKSAYSMAPNRVSCPFCSRKFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNNATTISNDAVTNNTNYMMRNVPERPFKCSNCPSSTFSTYSNLKKHISCKHSSNSPDDIKGYEGGSSEDEKLPSNGELKVEWDNHSGKPLNENMGAVQNSDLPFKCHLCDGSFAEREVALKHIKENHYAEFDLLISKNALDTNATTPDDNGHHEDEDNEMRGKFPDYSNRKVICAFCMRRFWSAEDLRRHMRTHTGERPFSCDICGRKFTLKHSMLRHRKKHNINMDSEIINSDEDINGAPTLEKFTKHDNILNMMKDKTDESDGNEGSDLISNLLGIRDRSFIDKVLTASADDAAKLLGVKNGIRE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -