Lhir010296.3
Basic Information
- Insect
- Lagria hirta
- Gene Symbol
- ZFY
- Assembly
- GCA_947359425.1
- Location
- OX375801.1:22064934-22082218[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 15 7e-06 0.00035 21.6 1.2 1 21 17 37 17 38 0.96 2 15 0.072 3.6 8.9 7.2 1 21 38 62 38 63 0.93 3 15 0.08 4 8.8 0.1 1 20 71 90 71 92 0.93 4 15 0.0048 0.24 12.6 1.3 1 21 95 115 95 116 0.94 5 15 0.00045 0.023 15.9 1.6 1 23 124 147 124 147 0.95 6 15 0.0014 0.072 14.3 2.3 1 21 189 209 189 210 0.96 7 15 0.0099 0.5 11.6 0.5 1 20 218 237 218 239 0.93 8 15 3.2e-05 0.0016 19.5 1.7 1 21 242 262 242 263 0.95 9 15 0.00057 0.029 15.5 0.2 1 23 271 294 271 294 0.90 10 15 2.4e-05 0.0012 19.9 2.0 2 21 306 325 305 326 0.94 11 15 0.038 1.9 9.8 3.2 1 17 334 350 334 351 0.95 12 15 0.0036 0.18 13.0 1.4 1 21 355 375 355 376 0.95 13 15 0.25 13 7.2 1.9 1 17 384 400 384 401 0.93 14 15 0.0015 0.075 14.2 0.8 1 20 408 427 408 429 0.94 15 15 2.2e-06 0.00011 23.2 7.0 1 23 437 459 437 459 0.99
Sequence Information
- Coding Sequence
- ATGCGCAGAGGATCTTTTTACGAAACTTTTTGCTATGGGACTTTGGGTTACGTTTGTTACACATGTGGGAAACAATATAAGCAGAGAAGCTCTTTAAAGCGCCACATCAAGTATGAGTGCTCTGATTTTAAATGCAActgtgggcggttttataaacataaacattctctgcgtcaacaccaaaaatatgaatgtggtaaggagcccagttttgcctgtgcaagctgtccttataaagctaaaacgaaagggaatctgaaatctcaCACAATTAACCCTCCTTTTCCTTGCGATACCTGTGGACGGCGCTACAAATACATCAAATCGCTTAATCAGCATAAAAAATTTGAATGCCAAAAGGAACCTTCGTTTTTCTGCAGCTACTGCTCATACAGATCAAAAACAAAAGGAAATCTGAAACTGCATATCAAAGGTGTTCATTTGAAAATACGATGTACTGCTAGATGTTGTTTAGTGTTTTTAACTTTTTGGAAGCATATAGACCAATACTGCCGAAGGAAAAGTAAAGACAATGTGCGCGGCAAAGGCTTGCTCATTGCTGATTTTCAGTGCGGAGGCTGTGGAAGGTTGTACAAATATAAGCAAACTTTGCGTCATCATCAAAAATATGAATGTGGTAAGGAGCCGACTTTTGCTTGTTCAAGTTGTCCGTATAAATCGAAGACAAAGGGAAATTTGAAAACTCACACGATCAACCGCAAATTTCCCTGTTCCACTTGCGGGAGGCGATACAGGCACAGAGAATCGCTTCAGAAGCATATTAAATACGAATGCCAGAAAGAACCTAGCTTTTTCTGCCCCTATTGTCCCTATAAAGCGAAAAGAAAAGGGAATTTAAAGGTTCATGTCGATGGGGTGCACCTCAAACTGAGAAGAAAAAATAATGGAATCATTCATTGTCCAAAATGTGGACGAAGCTACAGACATAAGAGCTCGCTCTACAAACATTTAAAATGGGAATGTGGCGTAGAATCGCAGTTTAAATGTCATTTATGTCACTATGTTTGTAAGCAAAGAGGCCATTTACAAAGTGACAAATTGTATTCTTGCGATCAGTGCTCAAATACGTACAAACACAGAGCCTCTTTATGGAAACATTTAAACTACGAGTGTGGCAAAACATCGGTTTTTTTCTGTAATCATTGTAATTACGCTTCTAAACATAAATCACTCTTAACGTATATGACTGATTCTGGACGCTATGCGTGTGGCCGATGTGGCTCAAATTACAAGAACAAGGGCCATTTGCAACGGCATTTGAGCTACGAATGTGGAGTTGATCCCCAATTTAAATGTAACATTTGCTCGAAAAGCTTTAAGCATAAAGCTCATCTTCGGAATCATTTGATGCGACATGTTAGTTCAAATAAATATTGA
- Protein Sequence
- MRRGSFYETFCYGTLGYVCYTCGKQYKQRSSLKRHIKYECSDFKCNCGRFYKHKHSLRQHQKYECGKEPSFACASCPYKAKTKGNLKSHTINPPFPCDTCGRRYKYIKSLNQHKKFECQKEPSFFCSYCSYRSKTKGNLKLHIKGVHLKIRCTARCCLVFLTFWKHIDQYCRRKSKDNVRGKGLLIADFQCGGCGRLYKYKQTLRHHQKYECGKEPTFACSSCPYKSKTKGNLKTHTINRKFPCSTCGRRYRHRESLQKHIKYECQKEPSFFCPYCPYKAKRKGNLKVHVDGVHLKLRRKNNGIIHCPKCGRSYRHKSSLYKHLKWECGVESQFKCHLCHYVCKQRGHLQSDKLYSCDQCSNTYKHRASLWKHLNYECGKTSVFFCNHCNYASKHKSLLTYMTDSGRYACGRCGSNYKNKGHLQRHLSYECGVDPQFKCNICSKSFKHKAHLRNHLMRHVSSNKY
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -