Lhir006177.1
Basic Information
- Insect
- Lagria hirta
- Gene Symbol
- -
- Assembly
- GCA_947359425.1
- Location
- OX375796.1:22716708-22726466[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 20 6.3 3.1e+02 2.8 2.3 2 23 190 212 190 212 0.95 2 20 2.5 1.2e+02 4.1 1.8 1 21 338 358 338 359 0.91 3 20 4.6 2.3e+02 3.3 5.1 1 23 388 411 388 411 0.91 4 20 0.2 9.9 7.6 0.1 5 20 421 436 420 438 0.92 5 20 0.21 11 7.5 0.3 1 23 444 467 444 467 0.91 6 20 0.00015 0.0077 17.4 0.2 2 23 539 560 539 560 0.98 7 20 0.72 36 5.8 0.3 1 23 577 598 577 598 0.87 8 20 9.9e-05 0.005 17.9 2.2 2 23 602 623 601 623 0.97 9 20 8.5e-05 0.0043 18.2 1.0 2 23 654 675 653 675 0.96 10 20 0.00044 0.022 15.9 3.4 2 23 723 744 722 744 0.97 11 20 1.8e-05 0.00088 20.3 4.0 2 23 782 803 781 803 0.97 12 20 0.061 3 9.2 4.1 3 23 823 844 823 844 0.90 13 20 0.00011 0.0058 17.7 1.7 1 23 864 886 864 886 0.98 14 20 0.00025 0.013 16.7 0.5 2 23 899 921 898 921 0.95 15 20 2.7e-05 0.0013 19.7 0.6 1 23 938 960 938 960 0.95 16 20 0.2 9.9 7.6 0.5 1 23 990 1013 990 1013 0.95 17 20 0.11 5.4 8.4 1.2 2 23 1024 1045 1023 1045 0.96 18 20 0.00036 0.018 16.2 0.6 1 23 1056 1079 1056 1079 0.97 19 20 5.2e-05 0.0026 18.8 1.2 1 23 1085 1107 1085 1107 0.99 20 20 0.0017 0.088 14.0 0.3 1 23 1137 1160 1137 1160 0.96
Sequence Information
- Coding Sequence
- ATGGATTGGCACATTTCGACGTGGAATTCCTGTTGCAGATTGTGTTTGTCGAACGCATTAGGCAATCTTCTATCTGTTTTTCATCGCGAAACAAACACTGTAGATTTGCAACAGAATGTTCTTAAATTCCTGGAGGTTAAGATTTTAGCTGATGATAAGCTTACAACTATGATCTGCGCTAATTGTATTGAAAAAATCAACAACTGGCAAACTTTCAAGCGAACATGTACAGAAAATCAAAGTAAATTGGAAGAATGGTTTACTGCTTCTACTGCTGCTACTACCAATGTCCAATCTAGCAATGATATTTCGAATAACGATATCCAAATTAAAGAAGAACCAATAGAAAATGTAATAATACCACCACCAGAAGTGATTCTTACAAATGGTGATGGACCAGTAATGAAGAATGAACCAATCGAAGAGGATTTCAATGATCTACCTCCGCCACTAACACCACAAGGCGAAGAAACTGAAGAGGTTGAAGTTGTTGCTTATTCTGAAAATGATAACAATGTAATGAATCCTGATACAAGTCAAGATTCTGAAATCATTGCTGATCCTCGTCGTTGCAAAACATGTTCGAAATTGTTAAGTTCGGTAACCAATCGGAAGAAACATGAAAAGGTCATGCATGGAGTAAGAAATCGCAACACATTTCCTGTTGCTGGAGGATCTACAGATTCTGATTTGGGTTCATTAAGCCAAGATGATCGCTCACAAAATTCGGTCGATTCTCAGCTCGATCAACCGAAAGCAGCCCAGCAGCGTGTCATATCAGAAGAGGATAAGAAAATCTTATTTGCTGCTGGATTAAAACTTTTACAGCGTGATTCAGCGCCTCCAATTGCAAGCGAGGAGCTTTCTCGAATTGAATTGAGTTATATTGATAAATGTAAAGCAATGTATAATATGTATACAACATTAGTGTGTGCCTGCCATAATGTTTCACATCCAAATCTGAAAGGATTATTATCGCATTTGCGGGCTTTGCGTGTCTGGTTTCCAGTTTTTACATGTTATCATTGTATGATTACTTTTACCGATCGATCGGCAAGTACCAAACATTATTTACGATGTCCACGATCGAATTTGGAAACATTAGTGAAATTATCGAATCTCAAAAGACGAAGTGAAGTGAAAACAAGGCTGTATCAAGTATATAAGTGTAATGATTGTAGATTTTTGTATTCGTTTCATGAAGATTATTGTAAGCATGTCGATGAAGAACATAGTCAAATTACGTTACCGTTAATTTGTACATGTGGTCGACAATTTTCAACACAAGAAGATTACAAAGATCATGTTTATATTAGTTGTTTGGTTGATTTTTATTGTGATGTTTGTTTTATCACTGTTAAAACGTTAACGGCTTTTAAGAAACATGCGGAAGAGGTACATGATGCATCTGAAGGATTTATATTGAGACAAGATGATAATTATAGACAAAGAAGATCTTTGCCAATGAGAGAAGCAAAAGTACCTAGTGTTAAAAGAGAGTATACCGATGAAAAGAATATTATAAGTGGAAAGAGACGTACATCATATAAACCAATTATTGATGATGATGAAGAGAAAGTTGTAAATCCATTATCAATTAAATATCCGGGTAACGAATGTCCAATATGTGTACGTGAATACTCTACAAATGCTAATATGTTACGTCATTATCGGACACACTTTAATGATGATGGCAGTTTAAAGGAGGAACATGTTGATAATTCAATATATTGTTGTCCCGATTGTGGTGGTATGTTTAATGTTGAGGAATGGGAATTGCATAAAGAGATGCATAAGAAAAAAACATGTAGTGAATGTAATAAATCATTCCAATTCCAATCCGAATTAGAACAACATCGAAGTACTCATTTGAATCTCAAACTCTACCGTGATTCCAAGACCCAAAATTATAAAAGTACAATGGCTAGTCCTAATAGTGAGGCTAATAATATAGTAATGATGTGTGAAGTTTGTGATCGAATGTTTACATCGAAAGAGAAACTTAAAGAGCATAAGTTAACTCATGATAAAAAGTTAATGCCGGTTCTAAAATCGAAAATCTCCGATGATGATGATGATGAAAAGCCAAGTAAACTTGATATTAAAAATCTATGGGTAGAAAATAATAAAAAAAGATCGATTTCAAAAGTTGATGAATTTCCTAAGCGATGTCAGCATTGTCCTAAACTCTTCAACACAAATGGTTCGTACACCAATCATATGCAAATGCATGAACGTGCTGGCAAAGCTAGAATTGTACCAGTTCGGGAATCAACTCGTATTCGGACGCCTGTACTCAAACAGGAAGTCAAAGATGAAGAATCAGAAGGAGAATCATATCAGACTTGCAAACGATGCTTTAAAGTATTTTCAAGCAAATCAACACTTCGAAATCATATGAAATCACACGGTGTAAATACCCCTCCCATAAACAAACCTAAGAAATATAATGCGAAAAAAGTCTGGTGTGATATATGTCATTGCGCGTTTGAAAATCTAGCTCATTTGAAGCGGCATAAAGCTGACGATCATGAAGAATCAATGCCTAATCTAGCACCTGAAGATGATGATTTGAAATCGCCATTTATTTTCACTTGTGACATTTGTGTGCAAACATTTACCTCAAAGACGGCGCTGAAAAAACACAAAGAACGTCATGAAAACGATGTGAAACCGATAGTTCGGAAACAGGTATATTGCAAATATTGTAAAATACCATTTATTAATCCTCATCAATTATCTATTCATATGAAAGAGGAGCATATGGAAGGTACTAAAGAGAAACCTGCCCCCAAAGATAGACCACTTGAATTCAAATGCAAAATATGTGGTAAAGTTTTTAATAGTTTTTCAGCGATGAATACACATCAAGGTTGGCATAAACGGGTTAGGCCGGAAAATAGTACTGTTGTTGATAAAAAAATTGAGTTGTTGCCGATTAAGGAAGAGCCTCTAGAAACAAAAGGTTTCAGATGTAACAAATGTAGTGTTATATGTCCGAGTGATACAGCACTACAAATACATATTCTGGAGAAACATCGAAATATTAATGCAACTGTTATGATGTCACGGTGTAGTATGTGTAATTTAGATTTCAGTTCGCTTGAAGAATATGATCAACATAAACGATTCCATGCAATGGTTGAAAAACAGCCGAAAAAGACATATTCCTGTAATCAATGCCCGGCGGCATTCAGCAAACTTGATGCTCTAAAAACACATACTCGACAATTTCACACCAAACAGCAAGGATACAAATGTCATTATTGTGATCGAGTATTTGAAAAAGCGAATTCATTGGGTATTCACCTAAAAGTACATGAAAAACAAAAACAGATCACTGGAACGCCTAGTACTGTAGCTCATACACCCCCTCCCGCACCATCAACACAATCTGCCCCCAAAAAATTCACTTGCTCGATTTGTAGCAAAGGTTTTGATATACCGAAAGAGCTCAGAACACATACAATGCAAGCACATCCTTTCTGA
- Protein Sequence
- MDWHISTWNSCCRLCLSNALGNLLSVFHRETNTVDLQQNVLKFLEVKILADDKLTTMICANCIEKINNWQTFKRTCTENQSKLEEWFTASTAATTNVQSSNDISNNDIQIKEEPIENVIIPPPEVILTNGDGPVMKNEPIEEDFNDLPPPLTPQGEETEEVEVVAYSENDNNVMNPDTSQDSEIIADPRRCKTCSKLLSSVTNRKKHEKVMHGVRNRNTFPVAGGSTDSDLGSLSQDDRSQNSVDSQLDQPKAAQQRVISEEDKKILFAAGLKLLQRDSAPPIASEELSRIELSYIDKCKAMYNMYTTLVCACHNVSHPNLKGLLSHLRALRVWFPVFTCYHCMITFTDRSASTKHYLRCPRSNLETLVKLSNLKRRSEVKTRLYQVYKCNDCRFLYSFHEDYCKHVDEEHSQITLPLICTCGRQFSTQEDYKDHVYISCLVDFYCDVCFITVKTLTAFKKHAEEVHDASEGFILRQDDNYRQRRSLPMREAKVPSVKREYTDEKNIISGKRRTSYKPIIDDDEEKVVNPLSIKYPGNECPICVREYSTNANMLRHYRTHFNDDGSLKEEHVDNSIYCCPDCGGMFNVEEWELHKEMHKKKTCSECNKSFQFQSELEQHRSTHLNLKLYRDSKTQNYKSTMASPNSEANNIVMMCEVCDRMFTSKEKLKEHKLTHDKKLMPVLKSKISDDDDDEKPSKLDIKNLWVENNKKRSISKVDEFPKRCQHCPKLFNTNGSYTNHMQMHERAGKARIVPVRESTRIRTPVLKQEVKDEESEGESYQTCKRCFKVFSSKSTLRNHMKSHGVNTPPINKPKKYNAKKVWCDICHCAFENLAHLKRHKADDHEESMPNLAPEDDDLKSPFIFTCDICVQTFTSKTALKKHKERHENDVKPIVRKQVYCKYCKIPFINPHQLSIHMKEEHMEGTKEKPAPKDRPLEFKCKICGKVFNSFSAMNTHQGWHKRVRPENSTVVDKKIELLPIKEEPLETKGFRCNKCSVICPSDTALQIHILEKHRNINATVMMSRCSMCNLDFSSLEEYDQHKRFHAMVEKQPKKTYSCNQCPAAFSKLDALKTHTRQFHTKQQGYKCHYCDRVFEKANSLGIHLKVHEKQKQITGTPSTVAHTPPPAPSTQSAPKKFTCSICSKGFDIPKELRTHTMQAHPF
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -