Basic Information

Insect: Lacanobia wlatinum
Gene Symbol: THAP3
Assembly: GCA_947578705.1
Location: OX388051.1:8972401-8999021[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.41 36 5.8 0.7 1 23 354 376 354 376 0.91

2 10 0.014 1.2 10.4 1.1 1 23 383 406 383 406 0.93

3 10 0.17 15 7.0 0.2 1 23 410 432 410 432 0.92

4 10 0.11 9.2 7.6 0.9 1 23 437 460 437 460 0.97

5 10 0.0032 0.28 12.4 0.7 1 23 464 487 464 487 0.95

6 10 1.3 1.1e+02 4.2 0.1 2 20 499 517 499 519 0.81

7 10 0.29 26 6.2 0.2 2 23 575 597 574 597 0.95

8 10 0.0038 0.33 12.1 0.6 2 20 613 631 612 634 0.92

9 10 2.9e-05 0.0025 18.8 3.1 1 23 640 662 640 662 0.99

10 10 0.00033 0.029 15.5 1.0 1 20 669 688 669 690 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.41	36	5.8	0.7	1	23	354	376	354	376	0.91
2	10	0.014	1.2	10.4	1.1	1	23	383	406	383	406	0.93
3	10	0.17	15	7.0	0.2	1	23	410	432	410	432	0.92
4	10	0.11	9.2	7.6	0.9	1	23	437	460	437	460	0.97
5	10	0.0032	0.28	12.4	0.7	1	23	464	487	464	487	0.95
6	10	1.3	1.1e+02	4.2	0.1	2	20	499	517	499	519	0.81
7	10	0.29	26	6.2	0.2	2	23	575	597	574	597	0.95
8	10	0.0038	0.33	12.1	0.6	2	20	613	631	612	634	0.92
9	10	2.9e-05	0.0025	18.8	3.1	1	23	640	662	640	662	0.99
10	10	0.00033	0.029	15.5	1.0	1	20	669	688	669	690	0.96

Sequence Information

Coding Sequence: ATGAGGTGTAGTGTTCAAAATTGTTCTAATGATACAAGAAGAAATAACAAAAGCCATGGAATCACATTTCATCTGTACCCAAAACAGCTAAACCAGCGGAATGCCTGGGTGGAAGCACTGGGCATGTCAGACTGGGAACCTAAAGAAAGAAGCTGCGTATGTTCCGAGCACTTCCGGAACGAAGACTTCTATACAACCAAGGGTGGCTTAAGGAGAATCAAGTGTGGAGCTGTGCCCTCTGCCATGACTGAAGCGCTAGGCGATCTTGATGCGCCAGCCTCGTTGAGGGTGTGCCGGATATGTCTCGTAATGGACACTAAAATGTACCACATTAGAGAACACAAGCTGGATCAAATGTACGAGCATATCACTGGGTTAGTGGCTAGTCCAGAAGACCGGTTCCCGCAGCGTGTGTGTTGGGAGTGCGCCGGCCGACTGTCCGCGGCGTGTCGCTTCAGGAGCAAGGCGCTACGCAGCGATGCGGTGCTACACGAGATGTTGCGCTCTGATACTTATATAAAAATCCGTGATATAAGAGCAGTCAACAGGAAACATAACGACCTAAGTTCAACTTTAGTTCAACACATATACGAAAACGACGATTTTGATGTTCTCGTTAAAGATTTAGCGATTAAAACTGAAGAAATGAACGATACAACAGATGCGCCTACAGATACTGAAACTGAAGATATTGATGTAAAAATAACTGAAGTCCCAGTAAAGGACGAAAGTAATCACAATGAGATATTCTTCGATGAGTACGACCATTTTGATGATGATGACGAGAAGGCATTAAGTGAAGTTTATGTGGAACAGAAAGAGATCCCTAAAGTAAAGAAGAAAAGGGTGAAAGTCGTTAAAAAGGATAAGGCGAAGAAAGTTGAGGAGGAGAATGATCCGGATACTTGTGGTGATAAGTTCAAAACAACAGACGTAAAACGCCGTCGTACTACGGAAAGCTTTGAGGAGACTCTGTTCACTGTCACGCCGCTAACATACGACCAACAGATAGAGGAGATCATGAAGAGACAGGAGAGTTACAACTATACAAGTGCTCCTTATAAGTGTACAGTATGTTATCGGGGGTTCCAGATAAAGGATCGGTTCGATGCTCATGTTGTGAGGCATAGTGAGCAATGCGGTGCTTACGAGTGTTTTATCTGCAAATCTAGGTTGAAAACTAGTCGCGCGCTTCGAAAGCATTTAACAGCTCAGCACACAGAACAATATACGTGTAAGGGATGTCCGTTTGTCACTAGGAATCGTGGTGTAGCGAGGGAGCACGAAAAATGGCATTCAGGCACTAAATACCAGTGTCCACACTGTGCCAGTGAGTTTGATAAAATAACGACATACATGGGTCATATTCGTATCAAACATGTGTCAGACTTCGTTTGCGAGCTCTGTGGGTATACATTCATCAGTAAAAAGGGGATCGATGTACATAAGAAGAAGAAACATCGaatgtataaggagATCCCATTAGAGGGGCCGTACTGCGAAATATGTGATGTGAAGTTCGTCTCAGAAGACGCCCATGACAGACATCTGAAGCTATCTTCAAGGCACAGCAGTGATCATGACCCTAACCGAATCAGAAACGATTCTCAAAGTATGAACGCAGAAAAAAGCGGTCGAGTTATGCGCCGCATAGAGAGGAGGCCGGTCATACATCCTCGCTTACCTACCGACGACGAGCAACAGGAGACCCACGCGCCCGTCAGCTGTGAACAGTGTGGCATGCAGCTAGAAAACCTGCGACTCTACGCGCAACACTTCAGACGCGCCCACCCCGATAAGAACCGCACCAAGTATCCCGCAGTGAAGACACCCTGCATGTGCGAGCAATGCGGCAAGATATTCCAGAGCATGGCCCTCCTAAAAGACCACATGTGGGTTCACACCGGAGAAAAGCGATTCAAATGTGATCGCTGCACGAAAAGCTTTACACAGAAGACTAACCTAGTGTTCCATATGCGGGTCCATAGCGCGACGCGACCTAGCTACGAGTGTCCCTTATGTGGCAAACACTTCGCGTTCTACAATAATAGGAGACGACATATGTTTGCGGATCCACTGCGCGACGCGGCCGAGCTATGA
Protein Sequence: MRCSVQNCSNDTRRNNKSHGITFHLYPKQLNQRNAWVEALGMSDWEPKERSCVCSEHFRNEDFYTTKGGLRRIKCGAVPSAMTEALGDLDAPASLRVCRICLVMDTKMYHIREHKLDQMYEHITGLVASPEDRFPQRVCWECAGRLSAACRFRSKALRSDAVLHEMLRSDTYIKIRDIRAVNRKHNDLSSTLVQHIYENDDFDVLVKDLAIKTEEMNDTTDAPTDTETEDIDVKITEVPVKDESNHNEIFFDEYDHFDDDDEKALSEVYVEQKEIPKVKKKRVKVVKKDKAKKVEEENDPDTCGDKFKTTDVKRRRTTESFEETLFTVTPLTYDQQIEEIMKRQESYNYTSAPYKCTVCYRGFQIKDRFDAHVVRHSEQCGAYECFICKSRLKTSRALRKHLTAQHTEQYTCKGCPFVTRNRGVAREHEKWHSGTKYQCPHCASEFDKITTYMGHIRIKHVSDFVCELCGYTFISKKGIDVHKKKKHRMYKEIPLEGPYCEICDVKFVSEDAHDRHLKLSSRHSSDHDPNRIRNDSQSMNAEKSGRVMRRIERRPVIHPRLPTDDEQQETHAPVSCEQCGMQLENLRLYAQHFRRAHPDKNRTKYPAVKTPCMCEQCGKIFQSMALLKDHMWVHTGEKRFKCDRCTKSFTQKTNLVFHMRVHSATRPSYECPLCGKHFAFYNNRRRHMFADPLRDAAEL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01339466;
90% Identity: iTF_00851871;
80% Identity: iTF_00851871;