Lwla000946.1
Basic Information
- Insect
- Lacanobia wlatinum
- Gene Symbol
- Bcl11a
- Assembly
- GCA_947578705.1
- Location
- OX388042.1:5413222-5440834[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 25 0.13 12 7.3 8.6 1 23 282 304 282 304 0.96 2 25 1.7e-05 0.0015 19.5 1.9 2 23 312 333 311 333 0.95 3 25 0.15 13 7.2 0.3 1 23 337 359 337 359 0.97 4 25 0.00018 0.016 16.3 2.8 1 23 364 387 364 387 0.97 5 25 0.0029 0.26 12.5 0.2 3 23 393 414 392 414 0.96 6 25 0.0072 0.63 11.3 0.1 2 20 430 448 430 450 0.94 7 25 0.0018 0.16 13.2 0.1 3 23 464 485 464 485 0.95 8 25 0.0012 0.1 13.7 1.3 2 23 508 530 508 530 0.96 9 25 0.058 5.1 8.4 2.1 2 23 542 563 541 563 0.96 10 25 0.00039 0.034 15.3 4.9 1 23 569 591 569 591 0.99 11 25 5.4e-05 0.0048 18.0 0.2 1 22 597 618 597 618 0.95 12 25 5.1 4.5e+02 2.3 1.8 8 23 640 655 639 655 0.88 13 25 5.4e-05 0.0048 18.0 0.2 1 22 661 682 661 682 0.95 14 25 5.1 4.5e+02 2.3 1.8 8 23 704 719 703 719 0.88 15 25 5.4e-05 0.0048 18.0 0.2 1 22 725 746 725 746 0.95 16 25 5.1 4.5e+02 2.3 1.8 8 23 768 783 767 783 0.88 17 25 5.4e-05 0.0048 18.0 0.2 1 22 789 810 789 810 0.95 18 25 5.4e-05 0.0048 18.0 0.2 1 22 853 874 853 874 0.95 19 25 5.1 4.5e+02 2.3 1.8 8 23 896 911 895 911 0.88 20 25 5.4e-05 0.0048 18.0 0.2 1 22 917 938 917 938 0.95 21 25 5.4e-05 0.0048 18.0 0.2 1 22 981 1002 981 1002 0.95 22 25 0.0028 0.24 12.6 0.1 1 22 1045 1066 1045 1066 0.95 23 25 0.0028 0.24 12.6 0.1 1 22 1109 1130 1109 1130 0.95 24 25 4.7e-06 0.00041 21.3 0.3 1 23 1173 1195 1173 1195 0.98 25 25 0.0015 0.13 13.4 0.9 1 23 1201 1224 1201 1224 0.98
Sequence Information
- Coding Sequence
- ATGGGGGACATTCAAGTGTGCCGTATTTGTTTAAATATGGATGTGAAAATGCAGGACCTGGCGGCATACCCATTAGAATCTTATTTTGCATCATTCATGATGGAAAGTAAACCCTTATTCACCAGCTTGCCACCATATGCCTGCTACGAGTGTGCAGCTCTCGTCAAGAAGTTTTATTTATTTAGAGAGAAGTGTCTGCGGAGCCAGGGTCTGCTGTGTGGAATCATTGATGATTGTGGAAAGTTGACACGTCCAGCAATAAAATCCATCCCCCGAAAAAATCTCCTCGCAGTTTACAATGTCACTAACATAAACATAGACCAGGATAGCACAACAGAAAGACCACAGTTTGTCATAGAAGTTATCAAGCAGGAGGATCATGATCACATTGATGTTCCTGATCATGTCAGTCCTGATAATAGCTCTAGTGATGATGATGATGATGAGGGATGTGGGAAGAGTGATAAGAATAAAATACATGAAGTGGAGAAGGTGGAGATTTCTGTGAAGATGGATCTTGAGGAAGAGTCTGATAGTCCAGAGTTTCCCGATACAAAAATCGAGAAGCCAAAATTGACAGTCAAGAAATCCCAGTCAACCCAGTCCAAAAAGCGAGTAAGACAAAAGAGAACTCGTACGACTGTTGCTAAGAAGAGTTCAGCCAAAGTCAAGAAGGACGACACAGAATGTGGCGACAACACTGATGATTTGATTAATGTTATTACACTGTCGAAAACTTTGGATGAATCTGTGCTTTTAGAAATGACTTCTTACCCACAGCTCGAAGACCAGTTGGAAGAGATGAACAAACGCAAGCAGTCGTCCAACTACCTCGACTGTCCGTACAAATGTCACCAGTGCTACCGGGGCTTCAACAACACACATGCCTGGAAACATCACCTTACCAAACACTCCCCGAATCTCGGCGACATAGAGTGTAAAATCTGCAAGTACAGGTTCAAAACGAAACGAAACCTTCAGAGACACGCTCTAAACCACGGCAAGAGATATGTTTGTAATTTATGTCCGTACAACTCTAGCAATATAACTACTGTGAAGCAGCATCAAGGGTCACATAAGGGAGTCACGCATAAATGCAAATATTGTGATGAAGTTTTCAATGTAAGAACGACGTATGTCAGTCACATGCGAATCAAACATCCTTCAGAAAATATCTGCGGTTTTTGTGGGTACTCCTTCTATAGCAAGCAGGGGCTCGTCGTACATAAGAACATGATGCACAAGGATCTTGATACAAAACAAGAAGAGAATGCGGAAGAAGGTCCATACTGTGAAGATTGTGACGTCAAGTTTATATCGACGGAGGCGTACAAGAGACACATGGTGATGTCAGTCAAACACACGCGGACTACACACTCTATGAACGGGTGTCGTGTTTGCGGCGAGATATTCACGGACCCTGAGGAGTTACGTTTGCACAATCGTGAGGAGCATCCCAAGAAACAACCGAAGCACTACAATTATCAACGGAAGAGTCAAGTTCGAACGAAATGGCCGGCTAAGTGTCAACATTGTCCAGAAGAGTTCGCCACCCCTCGTTCGTACTGGAATCACTACCGGCTCAAGCATCCTGACAAGTATGAGCCAGTGAGGAAGAACTGCGTCTGTGATATATGTGGCAAGAGATATGCGTGCAACGCCGTCCTAGAGCTGCACAAGCGCACCCACTTCGGCGAGCGCCCCTACAAGTGCTCCCAGTGCGACAAGGCGTGCTTCTCAGCGCACGACCTGCGCGTGCACCAGCAGAAACACTCGGACACCAGACCCTTCCCCTGCAGCGTGTGCTCGCAAGCCTTCAAGCGGAAAGAAGCGCTGGAGAGACACTTGAAGCGTGTGCTCGCAAGCCTTCAAGCGGAAAGAAGCGCTGGAGAGACACTTGAAGGTAAGTTGTTACACAAGGCGTGCTTCTCAGCGCACGACCTGCGCGTGCACCAGCAGAAACACTCGGTCACCAGACCCTTCCCCTGCAGCGTGTGCTCGCAAGCCTTCAAGCGGAAAGAAGCACTGGAGAGACACTTGAAGCGTGTGCTCGCAAGCCTTCAAGCGGAAAGAAGCACTGGAGAGACACTTGAAGGTAAGTTGTTACACAAGGCGTGCTTCTCAGCGCACGACCTGCGCGTGCACCAGCAGAAACACTCGGTCACCAGACCCTTCCCCTGCAGCGTGTGCTCGCAAGCCTTCAAGCGGAAAGAAGCACTGGAGAGACACTTGAAGCGTGTGCTCGCAAGCCTTCAAGCGGAAAGAAGCACTGGAGAGACACTTGAAGGTAAGTTGTTACACAAGGCGTGCTTCTCAGCGCACGACCTGCGCGTGCACCAGCAGAAACACTCGGTCACCAGACCCTTCCCCTGCAGCGTGTGCTCGCAAGCCTTCAAGCGGAAAGAAGCACTGGAGAGACACTTGAAGCGTGTGCTCGCAAGCCTTCAAGCGGAAAGAAGCACTGGAGAGACACTTGAAGGTAAGTTGTTACACAAGGCGTGCTTCTCAGGGCACGACCTGCGCGTGCACCAGCAGAAACACTCGGACACCAGACCCTTCCCCTGCAGCGTGTGCTCGCAAGCCTTCAAGCGGAAAGAAGCACTGGAGAGACACTTGAAGCGTGTGCTCGCAAGCCTTCAAGCGGAAAGAAGCGCTGGAGAGACACTTGAAGGTAAGTTGTTACACAAGGCGTGCTTCTCAGCGCACGACCTGCGCGTGCACCAGCAGAAACACTCGGTCACCAGACCCTTCCCCTGCAGCGTGTGCTCGCAAGCCTTCAAGCGGAAAGAAGCACTGGAGAGACACTTGAAGCGTGTGCTCGCAAGCCTTCAAGCGGAAAGAAGCACTGGAGAGACACTTGAAGGTAAGTTGTTACACAAGGCGTGCTTCTCAGGGCACGACCTGCGCGTGCACCAGCAGAAACACTCGGACACCAGACCCTTCCCCTGCAGCGTGTGCTCGCAAGCCTTCAAGCGGAAAGAAGCACTGGAGAGACACTTGAAGCGTGTGCTCGCAAGCCTTCAAGCGGAAAGAAGCGCTGGAGAGACACTTGAAGGTAAGTTGTTACACAAGGCGTGCTTCTCAGGGCACGACCTGCGCGTGCACCAGCAGAAACACTCGGACACCAGACCCTTCCCCTGCAGCGTGTGCTCGCAAGCCTTAAAGCAGAAAGAAGCGCTGGAGAGACACTTGAAGCGTGTGCTCGCAAGCCTTAAAGCGGAAAGAAGCGCTGGAGAGACACTTGAAGGTAAGTTGTTACACAAGGCGTGCTTCTCAGGGCACGACCTGCGCGTGCACCAGCAGAAACACTCGGACACCAGACCCTTCCCCTGCAGCGTGTGCTCGCAAGCCTTAAAGCAGAAAGAAGCGCTGGAGAGACACTTGAAGCGTGTGCTTGCAAGCCTTAAAGCAGAAAGAAGCGCTGGAGAGACACTTGAAGGTAAGTTGTTACACAAGGCGTGCTTCTCAGGGCACGACCTGCGCGTGCACCAGCAGAAACACTCGGACACCAGACCCTTCCCCTGCAGCGTGTGCTCGCAAGCCTTCAAGCGGAAAGAAGCGCTGGAGAGACACTTGAAGATCCACTCCGGCGACAATCCATACAAGTGTGAAATTTGCGGCGTAGCATTCGCAAAGTCTTGTACGAGAACGCTTCACGTCCGCACCGTACACACGAAGGAACCGCCGCCGCCGCGCAAACGACGGAACAAAGTCAATAAGTAA
- Protein Sequence
- MGDIQVCRICLNMDVKMQDLAAYPLESYFASFMMESKPLFTSLPPYACYECAALVKKFYLFREKCLRSQGLLCGIIDDCGKLTRPAIKSIPRKNLLAVYNVTNINIDQDSTTERPQFVIEVIKQEDHDHIDVPDHVSPDNSSSDDDDDEGCGKSDKNKIHEVEKVEISVKMDLEEESDSPEFPDTKIEKPKLTVKKSQSTQSKKRVRQKRTRTTVAKKSSAKVKKDDTECGDNTDDLINVITLSKTLDESVLLEMTSYPQLEDQLEEMNKRKQSSNYLDCPYKCHQCYRGFNNTHAWKHHLTKHSPNLGDIECKICKYRFKTKRNLQRHALNHGKRYVCNLCPYNSSNITTVKQHQGSHKGVTHKCKYCDEVFNVRTTYVSHMRIKHPSENICGFCGYSFYSKQGLVVHKNMMHKDLDTKQEENAEEGPYCEDCDVKFISTEAYKRHMVMSVKHTRTTHSMNGCRVCGEIFTDPEELRLHNREEHPKKQPKHYNYQRKSQVRTKWPAKCQHCPEEFATPRSYWNHYRLKHPDKYEPVRKNCVCDICGKRYACNAVLELHKRTHFGERPYKCSQCDKACFSAHDLRVHQQKHSDTRPFPCSVCSQAFKRKEALERHLKRVLASLQAERSAGETLEGKLLHKACFSAHDLRVHQQKHSVTRPFPCSVCSQAFKRKEALERHLKRVLASLQAERSTGETLEGKLLHKACFSAHDLRVHQQKHSVTRPFPCSVCSQAFKRKEALERHLKRVLASLQAERSTGETLEGKLLHKACFSAHDLRVHQQKHSVTRPFPCSVCSQAFKRKEALERHLKRVLASLQAERSTGETLEGKLLHKACFSGHDLRVHQQKHSDTRPFPCSVCSQAFKRKEALERHLKRVLASLQAERSAGETLEGKLLHKACFSAHDLRVHQQKHSVTRPFPCSVCSQAFKRKEALERHLKRVLASLQAERSTGETLEGKLLHKACFSGHDLRVHQQKHSDTRPFPCSVCSQAFKRKEALERHLKRVLASLQAERSAGETLEGKLLHKACFSGHDLRVHQQKHSDTRPFPCSVCSQALKQKEALERHLKRVLASLKAERSAGETLEGKLLHKACFSGHDLRVHQQKHSDTRPFPCSVCSQALKQKEALERHLKRVLASLKAERSAGETLEGKLLHKACFSGHDLRVHQQKHSDTRPFPCSVCSQAFKRKEALERHLKIHSGDNPYKCEICGVAFAKSCTRTLHVRTVHTKEPPPPRKRRNKVNK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -