Lmin015478.1


Basic Information
Transcription Factor Domain
Sequence Information
Similar Transcription Factors

Basic Information

Insect
Labia minor
Gene Symbol
Pol_2
Assembly
GCA_963082975.1
Location
OY720346.1:29228734-29242638[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.038 6 8.6 2.7 1 23 269 291 269 291 0.95
2 11 0.0013 0.21 13.2 7.0 1 23 297 319 297 319 0.95
3 11 8.6e-05 0.014 16.9 5.1 1 23 325 347 325 347 0.99
4 11 1.6e-05 0.0025 19.2 2.7 1 23 353 375 353 375 0.97
5 11 0.00063 0.099 14.2 3.4 1 23 381 403 381 403 0.92
6 11 1.7e-05 0.0027 19.1 0.3 1 23 409 431 409 431 0.98
7 11 0.0025 0.39 12.3 1.3 1 23 436 458 436 458 0.96
8 11 4e-05 0.0063 18.0 0.1 1 23 464 486 464 486 0.95
9 11 0.00085 0.13 13.8 0.0 2 23 493 514 492 514 0.96
10 11 6e-05 0.0094 17.4 3.4 1 23 572 594 572 594 0.96
11 11 0.00082 0.13 13.8 2.2 1 23 604 626 604 626 0.97

Sequence Information

Coding Sequence
ATGAATGGGGTAATGGTTTTAAATGTTTACCCGACATTACAAACATGTTGTATAGGATGGGGTAGTTCTTTTATACCCATGCACTTTGACTCATTAAAAGTTGTATCAGAACATCTAGTGGAAAGAATCAAGCTGGAAGAGTCCGTTTTTAGGGATGTTTTACAAAATGCAACTCCATGCCCAATGTATGCCCCAACGAATTCGAATAACCCAGTCTTTAACCCCTGGGCCATAACAACCCAATATAATGTGAATAGTGGTGGAAGTTCTCTTAATATTGGCTTACCGAAATTACCACAGTCAAATGAAAATATCAACGAAGGGAATAATACTAGTGCAAAATCAAATACCAATTCCAACATGAACAATAATCTAATGTGTACTACAATGTTTTTcatgaatgaaaatattcaacAGAATACAGCTCATCAACCGAATAATAATGGTAAAAAACatcatgaaatatttaattttgcatgCGAGAAAGGTTGCAATTGTGAATCTACCCTTTTCCGTAATGGAAATACAATATTTGCTCCTGATAAGCAAATATCAAGTAAACATATTATGACCCCGTTGCCATTAACAGCCCAAGATTGTGGAgattttcttcttaaaaaaaCGACTGATGTCACAAATAATCAAAatgtaaatacaaataatacacCACCAAATGTACCTCATAAACCCCGTCAAGAGTTAACCCCTGGACAAGATCAACAGCAACAACCACCGCCACAACCTCCATTAATCCCACCTAGAAAACCACACGATCGTAAATATCGAGGTGACAAAGAACGGCCATTTACATGCATTGAATGTGGCAAATCATTTCTATTAAAACATCATTTGGTCACTCATGCAAGAATACATACAGGCGAACGCCCACATATATGCCCATCATGTGGGAAAAGTTTCGCCCATAAACATTGCTTAAGTACCCATCTTCTTTTACATAGCAGTGATCGGCCATATAAATGTCTTGAATGTAAAAAGTCATTTACTTTAAAACATCATCTTGTAACACACGCCCGAATCCATAGCAGAGAGAGGCCGTTTGTATGCCAAGAGTGTGGACAAACATTCACACAAAAGAGACATTTGGTAACACATGGAAAATATCATAGTGGCGAGAGGCCGTATGTATGTGACGAATGTGGAGAGTCGTTCTCTCAAAAAGAGCATCTTGTGTGCCATTCAAGATTCCATGGTGGATTACATTCATATGTTTGTTCTGATTGTGGTAGTAGTTTTGcaagaaaatttgaattagttAATCATGAAAGATTACATGGAAGAATTCCACATAGTTGTGATGTCTGTGGAAAAGAGTTTCTACAAAAAAGAACTCTCTTAGCACATTCAAGATTACATACAGAAGAAAGATCCTTTGTCTGTCAAGAATGTGGAGAAATGTTCACTAATAAAGCAGAACTTGTTGAACATAGTACGATTCATTCAGATAATAAATCTCTTATTTGTAGGGAATGCGGCAATGTTTTTGCTAGCCGAGAAGGTTTAGCACTTCATTTAAGACTTCATTCTGGTGATAGAAACGTTGTCGCTGATTTGTGTGGTTTGGCAACTGCACTACAACAACCTGCACATTTTCTATGTCCATCAACCCCACCAGCTGGTACCAGTAAATTTAATCAAGCATCTCAGGCGACTCCACCAACTGCAGCCACACCTAATCAACCCAAACCGAAACCCCATATTTGTAGAGATTGTGGTAAAGCATTTTCACAAAAACATGGTTTGGCGCAGCATAATAAGAGACATTCTGGAGGTACTTGTGATCTGCGTCAACATGTTTGTGAAAAATGCGGAAAAGCTTTCCTACAGAAAAATCATCTTGCATTACACGCTCGTCAACATTTAGATCCTGCTGAAAGAGCAGCACTTGATCAGGCTAGGCAACAAGCTCAACAACAAGCTCAGCAACAGGCTCAACAACAAGCCCAACAACAGGCAGCCCAGCATGTGCAACAgcaacagcaacaacaacaacaacagcagcAGCAACAACAACCACCACCGCCACAGCATCCGCCTCCTCCTCATCAACCTGAGCCCCCTGaaGCCTTCGATTGTGTAAATCACGTGAAGATAATTGAGATCTTGGAGTCTGTGGGTTTGGACAGGGGTGACCTGAACATCATCGCTAATCTCTTCTGGAGTCAAACGACCGAAATCAAAATAGAAGAACTAACAAGCGAAGCAATTTCCATCAAGAAAGGAGTACGCCAGGGCTGTGTCCTGTCCCCGCTTTTGTTCAACGTGTATTCCGAAGTGGTTTTTAGAGAGGCACTTGAGGAAACATCTGGCGGAATCAAGTTGAACGGAGTAAGAATCAACAACTTAAGATACGCAGATGACACGATAATCATCGCAGGCAGCCCTGGTGAATTACAACGGATGATTGATAATGTGGTACAGCACGAAAACTTTGGACTACATATTAATATCTCAAAGACCAAGCTAATGGTATTCTCAAAAACACCGAAAGCTGTCTCActtaaaataaacaacaaaactgTCAGTCAGGTGACTTATCTTAAATACCTGGGAGCCGTAGTAAATCAGGAATTCTAA
Protein Sequence
MNGVMVLNVYPTLQTCCIGWGSSFIPMHFDSLKVVSEHLVERIKLEESVFRDVLQNATPCPMYAPTNSNNPVFNPWAITTQYNVNSGGSSLNIGLPKLPQSNENINEGNNTSAKSNTNSNMNNNLMCTTMFFMNENIQQNTAHQPNNNGKKHHEIFNFACEKGCNCESTLFRNGNTIFAPDKQISSKHIMTPLPLTAQDCGDFLLKKTTDVTNNQNVNTNNTPPNVPHKPRQELTPGQDQQQQPPPQPPLIPPRKPHDRKYRGDKERPFTCIECGKSFLLKHHLVTHARIHTGERPHICPSCGKSFAHKHCLSTHLLLHSSDRPYKCLECKKSFTLKHHLVTHARIHSRERPFVCQECGQTFTQKRHLVTHGKYHSGERPYVCDECGESFSQKEHLVCHSRFHGGLHSYVCSDCGSSFARKFELVNHERLHGRIPHSCDVCGKEFLQKRTLLAHSRLHTEERSFVCQECGEMFTNKAELVEHSTIHSDNKSLICRECGNVFASREGLALHLRLHSGDRNVVADLCGLATALQQPAHFLCPSTPPAGTSKFNQASQATPPTAATPNQPKPKPHICRDCGKAFSQKHGLAQHNKRHSGGTCDLRQHVCEKCGKAFLQKNHLALHARQHLDPAERAALDQARQQAQQQAQQQAQQQAQQQAAQHVQQQQQQQQQQQQQQQPPPPQHPPPPHQPEPPEAFDCVNHVKIIEILESVGLDRGDLNIIANLFWSQTTEIKIEELTSEAISIKKGVRQGCVLSPLLFNVYSEVVFREALEETSGGIKLNGVRINNLRYADDTIIIAGSPGELQRMIDNVVQHENFGLHINISKTKLMVFSKTPKAVSLKINNKTVSQVTYLKYLGAVVNQEF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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