Basic Information

Insect: Kuschelorhynchus macadamiae
Gene Symbol: ZFHX3
Assembly: GCA_030620095.1
Location: JAUTXW010000108.1:597699-626649[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 9.6 2.4e+03 2.2 0.2 2 23 40 62 39 62 0.87

2 16 0.00037 0.094 16.1 1.8 2 23 202 224 201 224 0.95

3 16 9.2e-05 0.023 18.0 0.7 1 23 256 280 256 280 0.92

4 16 0.014 3.4 11.2 0.4 1 22 322 343 322 346 0.91

5 16 0.74 1.9e+02 5.7 1.4 1 23 595 619 595 619 0.91

6 16 2 5.2e+02 4.3 0.2 1 22 701 722 701 724 0.80

7 16 0.19 49 7.5 0.6 2 23 741 763 740 763 0.93

8 16 0.09 23 8.6 1.6 2 22 845 865 845 868 0.90

9 16 0.085 22 8.7 1.3 1 23 881 906 881 906 0.92

10 16 0.0063 1.6 12.2 1.6 1 23 924 946 924 946 0.97

11 16 0.0014 0.35 14.3 0.7 2 23 953 975 952 975 0.94

12 16 0.00075 0.19 15.1 3.0 1 23 1086 1110 1086 1110 0.92

13 16 0.011 2.7 11.5 0.6 1 22 1130 1151 1130 1154 0.89

14 16 0.0022 0.55 13.7 0.2 1 23 1203 1227 1203 1227 0.93

15 16 0.0064 1.6 12.2 0.5 3 21 1293 1311 1291 1312 0.91

16 16 1.1 2.8e+02 5.2 1.4 2 19 1444 1461 1443 1466 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	9.6	2.4e+03	2.2	0.2	2	23	40	62	39	62	0.87
2	16	0.00037	0.094	16.1	1.8	2	23	202	224	201	224	0.95
3	16	9.2e-05	0.023	18.0	0.7	1	23	256	280	256	280	0.92
4	16	0.014	3.4	11.2	0.4	1	22	322	343	322	346	0.91
5	16	0.74	1.9e+02	5.7	1.4	1	23	595	619	595	619	0.91
6	16	2	5.2e+02	4.3	0.2	1	22	701	722	701	724	0.80
7	16	0.19	49	7.5	0.6	2	23	741	763	740	763	0.93
8	16	0.09	23	8.6	1.6	2	22	845	865	845	868	0.90
9	16	0.085	22	8.7	1.3	1	23	881	906	881	906	0.92
10	16	0.0063	1.6	12.2	1.6	1	23	924	946	924	946	0.97
11	16	0.0014	0.35	14.3	0.7	2	23	953	975	952	975	0.94
12	16	0.00075	0.19	15.1	3.0	1	23	1086	1110	1086	1110	0.92
13	16	0.011	2.7	11.5	0.6	1	22	1130	1151	1130	1154	0.89
14	16	0.0022	0.55	13.7	0.2	1	23	1203	1227	1203	1227	0.93
15	16	0.0064	1.6	12.2	0.5	3	21	1293	1311	1291	1312	0.91
16	16	1.1	2.8e+02	5.2	1.4	2	19	1444	1461	1443	1466	0.90

Sequence Information

Coding Sequence: ATGCTCCGGCAGCCCACTCGACCTTCGGAGCTCCCAGCCGTGCACAGTTATCGCGTGGTGGCTTTGAGGGACGCCAGACCGCCCAGGCCGGCCTCCCTGCCAGTCAAACCTATCCTCATGTGCTTCGTGTGCCGACTGTCGTTCGGGTTCGCTCGGTCGTTTGCGAGCCACGCGAGCGCGGAACATGGAGTGGCGCTGCAGGATGCGGAGCGCGAAGTGCTTGCACAGGACTGCGGCGCAATCCTCCAGTGCGTGGGAGCCGAAAAGCGACCGATGGTTTCGCTGCTAGAACCTCTAGGAAGCCCCGTCGCTTCGGAACCTCAATTGATGCAACAACAAACCTCAATCTCCAGCCGAGTGGACATTAAGCAACCATTACCTCATCAGCAGCAAACGCAGTCTACTCCCGGAAAGTCCCCCAGTCCACCTTTCGCCTCTCCGCCCGCCTTCATGACGGGTACGACGATAGGTGTATGTCCCGAGCACCTCCAAGGTAGGCCATCGGGAGTGGATTGTCAACGTTGCGAGATGATATTGGCTTCAGGAAGGCTGGGCCCCGCCGGTTTGGCCAACGTTCATAGTAGGAACTCGTGCAAAACATTGAAATGTCCCAAGTGCAACTGGCACTACAAGTACCAAGAAACCTTGGAAATTCACATGAAAGAAAAACATCCCGAAGCGGAAACGAGCTGTATATATTGTATAGCGGGCCAACCTCATCCCCGGTTAGCAAGGGGCGAAACGTATACTTGCGGCTACAAACCGTACAGATGCGAAGTGTGCAATTACTCTACCACTACCAAAGGCAATCTGAGCATTCACATGCAGTCGGACAAACACCTGAACAACATGCAAGAGTTACAGAATGGAGGAGGTCCCAACGGTGAGGCGAGGCAAGCCTCCCCCAAAGCTCCCTCGCTTCATCATTCTCCTGTCAGTTCTGGGCACAAACCTAAACCTAGTTTTCGATGTGACGTATGCAATTACGAGACTAACGTGGCGCGAAATTTAAGGATACACATGACGAGCGAGAAACACACGCACAATATGTTGGTTTTACAACAGAACGTGAAACATATGCAAACCCTAAGTGCGTTGCATCACCAGCAACACCCACAGCAGCACATGGAGAGCTTATACGGAATGTACCCTGGACTTGGAGACAAGCCTGAGGCCGCTCTCGCGGACATGGCCTACAATCAAGCCCTGTTGATACAAATGATGACTGGAGGTCAACTCCCAGGCCACGCAAGCCCCGCGGAAATGGCTGCTCACTCCGACTTAGGTTTAAACCCCGAAACGATGGAACCTCCTCCGGAACCAGCGGATCCTGATCCGGATAAGACCTATCAATGTTGCGTTTGCAACCTATTCCAAACGGACTCCTTGGAAGAACTGGGGAGACATTTAGCTTTAGATAGAACCAGACTGAGGGAGCAAGAAATCCTAGCCGTGGTGGCGGGGCATTACGTGTGTAAGCTCTGCACGTACAAAACGAATCTCAAGGCTAATTTCCAGCTACATTGCAAGACTGATAAACATCTCCAAAGGCTGCAACATGTGAACCACGTGAAAGAAGGTGGTCCTCGAAACGAATGGAAATTAAAATACGCTTCAGCCCCCGGAGGTGTTCAAATTAGATGTAACGCCTGTGACTACTACACCAACTCGGCCCATAAGCTTCAGCTTCATTCGGCTGCTGGCAGACACGATGCTGGAGTGGCATTACTTAGACATCTCCTTGATAGATGTTCGAGTCTTCAACCGAACCAGCCAAGAGTGTTCCATTGCTCGCTTTGCGGGTTTTCATCTACGAACAGGTTACCTTTGTTGCAACACGTGAGGTCTCTGAAACACCTGCACATGGAACAGTTGCATCAGCTGCAAAGGCGGGCGGAAGGAAAGGAATCGTCTCCGGATATTGGGGAAGTTTTCCATGTGGTTCCTGGTCCTGTCGATCAAAGTCTGCAGCAGAGACAGACGCCTGaacaCCGCGACAGTATCACCTCTGAGCTTTCCCAAATGGACAATTCCAACCAAGTCAAAGCGGAACCCGGCGACCTAGAAGAACCCAATCACCTGGATTCGAACCCGGGTCCGCATATGTGTCCCTACTGTGATTATTCTAGCGACAGCGAGATGCGTATACAAGCACATGTTTTAGCGCAACACGGTCCCAACCATCCCGCCAATATTCAACAACAAGAACACCAAGTGATCCACTGTCCCTTATGTCAAGATTTGTTTAAAGACCGGACAAGCCTGGAAAGACACGTCATGCAGATCCATTCGGTCAACAGCGAGGGCCTTCAGAGGCTCCTGATGCTCGTGGACCAGAGTCATTGGCTGAATCAGGCTTCTAGAACGTCTACTCCGAACAACAACAGTGCTACAGCTCAAAATCAAGTTTCGCCCACTTCAGCGTCTTCCAAAGACTCCAGCAAGCTGGAAAAATGCGACAGTAGTCACAATGAAGAGAATCCCGACCTTTTGTCACCAGTTAGTGACGACACTAACGAGAATGAAAGTGAGAGGTGTAGTGCTTGCTATAAAACGTTTAGAAATGTTGATGAGTTATGTTTACATCAAAACGAGACTGGACATCAGTTAGAAGTCAAACAGACGCCTAGCGGCCCTGGTTACGTTTGTTGGAAGAAGGGTTGCAACCAGTTTTTTCCTACCGCTCATACTCTTCAAATGCACTTCAAAGAAGTGCACGCCAGAAACTCAATTGCCAATATGTCTGTAAGCGAGAAGCACGTGTACAAGTATAGGTGCAACCAGTGTTCCCTGGCCTTCAAAACGTTAGAAAAATTACAGTTACACTCTCAATACCATATGATAAGAGACGCCACCAAGTGTGTACTATGTGGACGCAGCTTTAGATCTCTGGTAGCGCTGCACAAGCACGTAGAGAGCGTGCATTCGGAGCTTACAGATGAAGAGCTGAACGCGTATAAACAAAGCTTGATGAACAATCCTTTATTGTTGGCAGGGCTTCAAGGACAGATCCTTGACAGTAATACGAACGATTTATTGAGAAAAGAAAGCATGAGAGGAGACGAGAACGAAACAAGTACAGCCGAATGCGATGACAGTAAAGATCTGAGCACTAGTCAGTCGTTGGACGAGAGCAACCAGAATGACGGGGAAAACTCTGACGATAGTATTATATACAAAGATCAGCAGTTTCTCGAGGACTACCTCAACAGCCAAGCCATGGCGGAGGATAGTTACAACGACCCCAATAGAAAGTACAAATGCCACAGGTGTAGAGTAGCCTTTACGCGACAGAGCTATTTGACGGCGCACAATAAGACTTTGTTGCATAGGAAAGGAGAAAAGCTAACTTATCCGATGGAAAAATACTTAGACCCGAATAGGCCCTATAAGTGCGACGTGTGCAAGGAGAGTTTTACGCAAAAGAATATTCTGCTTGTGCATTACAATTCGGTTAGTCACTTGCATAAATTAAAACGGGCCATGCAAGAGCAGGCGAACAATAACAATAACTCCCCAGTGTCGCCGATCATAGGCACTACGCAGGCGCAAAACCTTTCCTTGACCCCAAAAAGTACGGCCAGTGAAGAGGATGACAAGAAAAAATATCGGTGCAATATTTGTAAAGTCGCGTATACGCAAGGCAGCACGCTCGACATCCATATGCGGAGCGTTTTACATCAAACAAGGGCCAGTAAACTGCAAGATTTAGCGATGACCGGTCAAATCGACCTGTCCAAGCCGCTAATCGAGCAACCCGACGTCATACAGTCTCCGAAACAACCCTCTCCGATACCGAGTGGAGGGGAGGCGGCGAAACAACCCTGTCCTACCCCGCCCAGTCCGTCAGGTATGCCAGGTAGTCAAGGGATGTGCTGTGCCAAATGCGGGTCTTCTTTCGCGACACAGGATCAGTTGAGCGCGCACCAGCTGTACTGTCTCTTCGCGACGCCTATGGCAGTGCTTCAGGGCGCTACTAACGATGACAGGCCAGAATCCGAACAAGACGCACAGTCAAGAGCTATGTCCGGCAAAAAGGGTTCTCCGATTTACAAGCATTTGTTAGAAGGTTACGGGTTCGATCTGGTGATGCAATACAACGAGAGCCATCAGAGAAGACAAAGACAAGCGGAAAAAGAAAAAGCAGAGGCCGAGCAAAAGTTAAAGGAAAGCAAAGAGGAGGTTTCCACTGAGGACATTATGCAGGAGTCTCCGCAGGAGGTGACCGTCATTCCCGAGGTCAAAGAGGAAAAGTGCGAAGAGCCGGAAAAACAAAGTTTCAGTGATAAAGAGGAAGAAGTGACTAATCTACCCGAAGTGAGCAAATCTACGTGCCAAACGTGCAACAAAGAGTTTTCTAGTGTGTGGGTGCTGAAAAGCCATTGTGAGGAAGTGCATAAAGACCTGGTGCCTCTGGAATATCTCGAGAAGTACGCGCAACAGCTAAAAAATGAAATCGAGAAAAAGACTGTTGTGGTCACCGCGGCCACGAGTTCAACCACGAACGCTTTGCCCCGCGTTACCACCCCCACTACCGCAGTCGGGGGCAGTGCAACTCCTGAAACAGAGAACATTACACCCGAGAAAGAACCTGACGACAATAAAGAGGCACTGCACGTAAAACTCAACCTGCAAACGCCTCCAGAAGCAGCTTCAACGGCTCCAAGCACGCCTACGAGTAGCACAACACCTGCTAGCTCGACGGACTCCCTTCCTGCGAATATCCAAGCTATGCTGGCTCAAACGATGGCCCAAAACCCTATGGCTTTGGCCCAACAGATGTCCGAAATGCAAGCAGCTTTGAACGTGATGCAGCTTCAGCAGCTCAATTTTAACCCCGTGATGCAAATGATGGGAATGGGTCTGCCTCTTGGACTCAACGCTTTGGCTGCGATGAACCTGCAGCCGCCTTTGGTACCCCTCATGATGCCTCCCCCGCCCTACGATCCCATGGGACAATATGGCGGTCAGGACCAGCAGGCTATGATGGCTAAACAGCAAGCTGCGATGTTACAGCAGCAGGCGGTAAGTGTTtactaa
Protein Sequence: MLRQPTRPSELPAVHSYRVVALRDARPPRPASLPVKPILMCFVCRLSFGFARSFASHASAEHGVALQDAEREVLAQDCGAILQCVGAEKRPMVSLLEPLGSPVASEPQLMQQQTSISSRVDIKQPLPHQQQTQSTPGKSPSPPFASPPAFMTGTTIGVCPEHLQGRPSGVDCQRCEMILASGRLGPAGLANVHSRNSCKTLKCPKCNWHYKYQETLEIHMKEKHPEAETSCIYCIAGQPHPRLARGETYTCGYKPYRCEVCNYSTTTKGNLSIHMQSDKHLNNMQELQNGGGPNGEARQASPKAPSLHHSPVSSGHKPKPSFRCDVCNYETNVARNLRIHMTSEKHTHNMLVLQQNVKHMQTLSALHHQQHPQQHMESLYGMYPGLGDKPEAALADMAYNQALLIQMMTGGQLPGHASPAEMAAHSDLGLNPETMEPPPEPADPDPDKTYQCCVCNLFQTDSLEELGRHLALDRTRLREQEILAVVAGHYVCKLCTYKTNLKANFQLHCKTDKHLQRLQHVNHVKEGGPRNEWKLKYASAPGGVQIRCNACDYYTNSAHKLQLHSAAGRHDAGVALLRHLLDRCSSLQPNQPRVFHCSLCGFSSTNRLPLLQHVRSLKHLHMEQLHQLQRRAEGKESSPDIGEVFHVVPGPVDQSLQQRQTPEHRDSITSELSQMDNSNQVKAEPGDLEEPNHLDSNPGPHMCPYCDYSSDSEMRIQAHVLAQHGPNHPANIQQQEHQVIHCPLCQDLFKDRTSLERHVMQIHSVNSEGLQRLLMLVDQSHWLNQASRTSTPNNNSATAQNQVSPTSASSKDSSKLEKCDSSHNEENPDLLSPVSDDTNENESERCSACYKTFRNVDELCLHQNETGHQLEVKQTPSGPGYVCWKKGCNQFFPTAHTLQMHFKEVHARNSIANMSVSEKHVYKYRCNQCSLAFKTLEKLQLHSQYHMIRDATKCVLCGRSFRSLVALHKHVESVHSELTDEELNAYKQSLMNNPLLLAGLQGQILDSNTNDLLRKESMRGDENETSTAECDDSKDLSTSQSLDESNQNDGENSDDSIIYKDQQFLEDYLNSQAMAEDSYNDPNRKYKCHRCRVAFTRQSYLTAHNKTLLHRKGEKLTYPMEKYLDPNRPYKCDVCKESFTQKNILLVHYNSVSHLHKLKRAMQEQANNNNNSPVSPIIGTTQAQNLSLTPKSTASEEDDKKKYRCNICKVAYTQGSTLDIHMRSVLHQTRASKLQDLAMTGQIDLSKPLIEQPDVIQSPKQPSPIPSGGEAAKQPCPTPPSPSGMPGSQGMCCAKCGSSFATQDQLSAHQLYCLFATPMAVLQGATNDDRPESEQDAQSRAMSGKKGSPIYKHLLEGYGFDLVMQYNESHQRRQRQAEKEKAEAEQKLKESKEEVSTEDIMQESPQEVTVIPEVKEEKCEEPEKQSFSDKEEEVTNLPEVSKSTCQTCNKEFSSVWVLKSHCEEVHKDLVPLEYLEKYAQQLKNEIEKKTVVVTAATSSTTNALPRVTTPTTAVGGSATPETENITPEKEPDDNKEALHVKLNLQTPPEAASTAPSTPTSSTTPASSTDSLPANIQAMLAQTMAQNPMALAQQMSEMQAALNVMQLQQLNFNPVMQMMGMGLPLGLNALAAMNLQPPLVPLMMPPPPYDPMGQYGGQDQQAMMAKQQAAMLQQQAVSVY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -