Basic Information

Gene Symbol
-
Assembly
GCA_030620095.1
Location
JAUTXW010004349.1:560084-566307[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 4.7e-08 1.2e-05 28.3 1.4 1 23 150 172 150 172 0.98
2 10 0.00077 0.19 15.1 0.3 2 23 179 200 178 200 0.96
3 10 5.9e-06 0.0015 21.7 5.7 1 23 205 227 205 227 0.98
4 10 0.64 1.6e+02 5.9 3.2 3 23 235 256 234 256 0.87
5 10 0.00011 0.027 17.8 0.3 1 23 261 283 261 283 0.98
6 10 1.1e-05 0.0028 20.9 4.6 1 23 293 316 293 316 0.96
7 10 2.6e-06 0.00065 22.9 0.4 1 23 322 344 322 344 0.99
8 10 0.00019 0.049 17.0 0.3 1 23 350 372 350 372 0.95
9 10 3.5e-05 0.009 19.3 4.1 1 21 378 398 378 400 0.96
10 10 3.8e-05 0.0097 19.2 2.2 5 23 409 427 404 427 0.95

Sequence Information

Coding Sequence
ATGCGTACTCAAAGTTCAACTTTGCACACTCTCGTAGAAAAACCTATTTTCCCACAACTCCAAAGAAAACAATTTGAACAACCGGACAAAGTAGGCGCGAAAACAAATGACAACACCACgattatcTTTCATGACAGTATTTATCCTTCCTTCAACATAGATTCACTACCCCATAATTTAAATCTCATGGAGTCTTTTGATTGTCAGAAGTCTGAAAATATGCCAGCAAGCTCAGTAGTAGATCAACTAAATGCTTCAGATGAATTGCTGAATCTTCTATCGACTGAAGAAGAATGCACCGCCATTTTGAACAACATAGCGAGAAATGACCAGTTCCAGACATTGATTCCTGAAAGCGATTTTGTGAAGATGACTGATGTTCAACCGCTGTCTGGCCGTCTAAGTGAAATTCCGAATACGTATGCCAAAGCCCATAGGCAGAACTTGTTCACTTGTGATATTTGTGGTAAGGTATTTACAACGAAAAAACTTCTAAAGAAACATTTAATTCGCCACAACGAAAAACCCACAATCCCCTGTGAGACATGTGGAAAACTGTTTCGATTTAAATATGAAGTTACTGATCATGCGCGATCCCATTCCAAGCCTACGTTTCAATGTGATATCTGTTCTAAAATGTTCATTCACAAATCGCATTTAAATGCTCACAAAAAGCGACATTTAGAACAGTTCGTTGCCTTTTGTGATATTTGCAATAAAGGTTTCATATCACAGCATGAATGTGTCAGCCACAAGAATGCTACGCATAACAACACTGGTTTTGTTTGCGAGACGTGTGGTCAAAAATTGAGCAGTTCGTTTGCACTAAAAGAGCACATGAATCTTCACAGCCTCTCTCATGGAAAGGAAAGGAATCATGTTTGTGAAGTGTGTCATAAAACTTataccacaaaaagaaatctcAAAGCTCATTACATGAAAATTCATTCTAATACTAAAAGGTATGTCTGCTCAATTTGTCGGAAGTCCTTAAGTAGTAAAAGTGCTCTTGAAACTCATATTAAAATGCATACAGGTCTCAAAGACTTTCTGTGTACTATATGTGAGAAACTGTTTGCTTCAAAGGAATATTTAGATGTTCATCAAAGAATTCACACCGAATACAAGCCTTACCAATGCACGTTATGCCCTaaaaaatttactcaaaaaaCGTCTCTTACAGTTCATTTAAGATGTCATACTGGCGAGAGGCCATACAAATGTGAGTGTGGAAAGAACTTTATTTCAAAAAGTCATTTAATGTCTCATTACAGAACTCATGACGTAGGTGGGGTGGATATTGATTATTTGAACTATCAGTTGCATGATTccttacagtaa
Protein Sequence
MRTQSSTLHTLVEKPIFPQLQRKQFEQPDKVGAKTNDNTTIIFHDSIYPSFNIDSLPHNLNLMESFDCQKSENMPASSVVDQLNASDELLNLLSTEEECTAILNNIARNDQFQTLIPESDFVKMTDVQPLSGRLSEIPNTYAKAHRQNLFTCDICGKVFTTKKLLKKHLIRHNEKPTIPCETCGKLFRFKYEVTDHARSHSKPTFQCDICSKMFIHKSHLNAHKKRHLEQFVAFCDICNKGFISQHECVSHKNATHNNTGFVCETCGQKLSSSFALKEHMNLHSLSHGKERNHVCEVCHKTYTTKRNLKAHYMKIHSNTKRYVCSICRKSLSSKSALETHIKMHTGLKDFLCTICEKLFASKEYLDVHQRIHTEYKPYQCTLCPKKFTQKTSLTVHLRCHTGERPYKCECGKNFISKSHLMSHYRTHDVGGVDIDYLNYQLHDSLQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-