Basic Information

Gene Symbol
-
Assembly
GCA_029255805.1
Location
JARACZ010000025.1:2321919-2337256[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.019 1.6 10.2 2.9 1 23 249 271 249 271 0.98
2 10 0.039 3.3 9.2 2.8 2 23 279 301 278 301 0.92
3 10 0.00084 0.07 14.5 2.3 2 23 333 355 332 355 0.94
4 10 1.4 1.1e+02 4.4 0.1 3 23 364 385 363 385 0.95
5 10 0.0025 0.21 13.0 0.0 2 20 390 408 390 410 0.94
6 10 0.37 30 6.2 0.1 2 23 418 440 417 440 0.88
7 10 0.32 27 6.4 0.2 2 21 445 464 444 465 0.93
8 10 4.4e-05 0.0037 18.5 1.7 1 23 521 543 521 543 0.99
9 10 2.8e-05 0.0023 19.2 0.7 1 23 549 571 549 571 0.99
10 10 0.00039 0.033 15.6 0.4 1 23 577 600 577 600 0.97

Sequence Information

Coding Sequence
ATGAGTTTAGACAATATTAAATCTGAAGGCGAGGAGGTGTTGGCATGTCGCGGGTGCCTGGCGACCGGAGTCAGCCTCTACAGCATTCACGAAAAAGGACTGGCTCAAGTCTTCGGAGATTTTACTGGGTTTCCTGTGGTACCATCAGACAGCTACCCTCAGCGGCTCTGTGCCATGTGTGTGGCGCAGGTACAGAAGTTCCTTGCGTTCGGCATCCGCTGCCACTCTGCCATGTACATTCTCCAGCAGATGGAGATGACCAGCTGCAAGATAACAACAGATTCTCTGGCAAACATTGAAAGAGCACACATCAAacttaatttacaaaaaacaaacgTAGAAACTATTAGTTTTGACGGCGTCAAAACCACAGACCCTAGAGAATCAAACCACACTGAGAAAAAGTATGAGAACGAGACAAAAACTATAGAACAATGCATGGTCAATGAAGATTTGACGGAAGATGATGATAAACCGTTAAAACATTTGGTGTCAGCGTTGTTTGGGAGCGAACTGAGTATTCCCAAGGAGGAAGATGATTTTAGTGAAAATAATGGAGCAGTTGATGATACGCATATGGATTCAGATAGCGACTGTTCAGCGAAGAGATCCACTAGGCATTCAGTAAATCTAACCCGGCAACTATCCCAGCTATACAATATGGAGGTCAAATTCCTGAGCATAGAAGACCACAAACGGGAGATAGAAGACCGCAGAAACTCTGACAAGTTCGTCAACGCCCCCTATCGGTGTGAGCTGTGCTGCAAAGTATATGTTTTTGAAGATACCTACAAAAGGCACATGATTTCTCATGATCCGAGTAGCGGTGACGTAGAATGCGAGATATGTCAATACCGCTTCAAAAACAGGAAGCGGTACATGAACCATTTCCACATTTATCACACAAAGAAGATCATATGCAAAGAGTGTGGAGTGGTCAATAGAGCGTGGAATTTCGCGAAACAGCACTACAAGTGGCATGGCGGCGTCACTACTGTCTGTGACCAGTGTGGCAAGCATTTCCCCGACAAAAAACTGTACTGCATGCACGTGAGAGCCGTCCACCGCGCGGAATTAGCAACTACCCTCTGCTTGCTCTGTGGCGACACCTACAACGGGGAAACTGGGCTGCGCATGCACATGGACAAAGCCCATAGACagGCGGCGCGGTGCGTTGATTGCGGTGCGATGTTCCGCAGCACAGACGCACTTGAAGCACACATAGCCAATACTTGTACACCGGGCGGGAgTTCGTGTCCGTTGTGCGGCGCCAACTTCCCATCTGACAGCGTCATGCGCGACCACTACGACCAACTGCACAAGACCACGCTCGTCTGTGAACAGTGCAACAAACTACTGCCTACCCTCGTGCTGTTCAAGAAGCATGTGAAAAGGTGTCTCTTACCGCGCGAGCAGGAGACGCGGCGGCGGGGAAACAAGGAGAGAGGCACCAAGCAGATCTACAACCTCAATCTCATGTGCGAACTGTGCGGCAAGGGGAACTTCAAGtGTTTCTCAACGTTACGAAGCCACCAGCGCGTGCACACCGGCGAGCGCCCGTACAGTTGTGACATCTGTCAAAAAGGCTTCAGGGAAATGCAGTTCCTCAAGAACCACATGAAAACTCACACTGACGAGCGTCGCTACAAGTGTCCGTTCTGCCCAAAAGCTTTCCGCCAGATGGGGCATCGCGCCGCCCACATACTCACACACACGAAGGAGCGCCCGTTCGCTTGCACCACGTGCACCAAACGCTACACGGGTTTGACAGCTCTTAAGGAACACATCAACACCGCGCACCGAGGGTTGCCGCCCCGCCAGCGCGGCAGGCATCGCGACAAACAGGAGTTGTAA
Protein Sequence
MSLDNIKSEGEEVLACRGCLATGVSLYSIHEKGLAQVFGDFTGFPVVPSDSYPQRLCAMCVAQVQKFLAFGIRCHSAMYILQQMEMTSCKITTDSLANIERAHIKLNLQKTNVETISFDGVKTTDPRESNHTEKKYENETKTIEQCMVNEDLTEDDDKPLKHLVSALFGSELSIPKEEDDFSENNGAVDDTHMDSDSDCSAKRSTRHSVNLTRQLSQLYNMEVKFLSIEDHKREIEDRRNSDKFVNAPYRCELCCKVYVFEDTYKRHMISHDPSSGDVECEICQYRFKNRKRYMNHFHIYHTKKIICKECGVVNRAWNFAKQHYKWHGGVTTVCDQCGKHFPDKKLYCMHVRAVHRAELATTLCLLCGDTYNGETGLRMHMDKAHRQAARCVDCGAMFRSTDALEAHIANTCTPGGSSCPLCGANFPSDSVMRDHYDQLHKTTLVCEQCNKLLPTLVLFKKHVKRCLLPREQETRRRGNKERGTKQIYNLNLMCELCGKGNFKCFSTLRSHQRVHTGERPYSCDICQKGFREMQFLKNHMKTHTDERRYKCPFCPKAFRQMGHRAAHILTHTKERPFACTTCTKRYTGLTALKEHINTAHRGLPPRQRGRHRDKQEL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-